SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1m68'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FWE_C_HAEC989_1
(UREASE)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		5 / 6 HIS A   7
HIS A  40
HIS A 101
HIS A 131
ASP A 192
 ZN  A 302 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 303 (-3.2A)
ZN  A 303 (-3.4A)
ZN  A 302 (-2.6A)
 1.23A 1fweC-1m68A:
6.2		 1fweC-1m68A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IIU_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		5 / 11 LEU A 228
LEU A 220
ALA A 148
ALA A 154
LEU A  95
 None
 1.16A 1iiuA-1m68A:
0.0		 1iiuA-1m68A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ITU_A_CILA451_1
(RENAL DIPEPTIDASE)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		6 / 12 ASP A 192
GLU A  73
HIS A  40
HIS A 101
HIS A 131
ASN A 134
 ZN  A 302 (-2.6A)
ZN  A 303 ( 2.3A)
ZN  A 301 (-3.2A)
ZN  A 303 (-3.2A)
ZN  A 303 (-3.4A)
None
 1.12A 1ituA-1m68A:
8.1		 1ituA-1m68A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ITU_A_CILA451_1
(RENAL DIPEPTIDASE)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		5 / 12 GLU A  73
HIS A 101
HIS A   7
ASN A 158
ASP A 192
 ZN  A 303 ( 2.3A)
ZN  A 303 (-3.2A)
ZN  A 302 (-3.2A)
None
ZN  A 302 (-2.6A)
 1.38A 1ituA-1m68A:
8.1		 1ituA-1m68A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT5_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		5 / 12 LEU A 228
LEU A 220
ALA A 148
ALA A 154
LEU A  95
 None
 1.12A 1kt5A-1m68A:
0.0		 1kt5A-1m68A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		4 / 4 HIS A  40
GLU A  73
HIS A   9
HIS A 194
 ZN  A 301 (-3.2A)
ZN  A 303 ( 2.3A)
ZN  A 302 (-3.3A)
ZN  A 301 (-3.3A)
 1.12A 1utzA-1m68A:
undetectable		 1utzA-1m68A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_A_CRNA401_1
(CREATININE
AMIDOHYDROLASE)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		5 / 8 GLU A  73
HIS A   9
ASP A 192
HIS A 131
HIS A  40
 ZN  A 303 ( 2.3A)
ZN  A 302 (-3.3A)
ZN  A 302 (-2.6A)
ZN  A 303 (-3.4A)
ZN  A 301 (-3.2A)
 1.13A 1v7zA-1m68A:
undetectable		 1v7zA-1m68A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_B_CRNB3401_1
(CREATININE
AMIDOHYDROLASE)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		5 / 8 GLU A  73
HIS A   9
ASP A 192
HIS A 131
HIS A  40
 ZN  A 303 ( 2.3A)
ZN  A 302 (-3.3A)
ZN  A 302 (-2.6A)
ZN  A 303 (-3.4A)
ZN  A 301 (-3.2A)
 1.14A 1v7zB-1m68A:
undetectable		 1v7zB-1m68A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_C_CRNC4401_1
(CREATININE
AMIDOHYDROLASE)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		5 / 8 GLU A  73
HIS A   9
ASP A 192
HIS A 131
HIS A  40
 ZN  A 303 ( 2.3A)
ZN  A 302 (-3.3A)
ZN  A 302 (-2.6A)
ZN  A 303 (-3.4A)
ZN  A 301 (-3.2A)
 1.14A 1v7zC-1m68A:
undetectable		 1v7zC-1m68A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_D_CRND5401_1
(CREATININE
AMIDOHYDROLASE)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		5 / 8 GLU A  73
HIS A   9
ASP A 192
HIS A 131
HIS A  40
 ZN  A 303 ( 2.3A)
ZN  A 302 (-3.3A)
ZN  A 302 (-2.6A)
ZN  A 303 (-3.4A)
ZN  A 301 (-3.2A)
 1.15A 1v7zD-1m68A:
undetectable		 1v7zD-1m68A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_E_CRNE6401_1
(CREATININE
AMIDOHYDROLASE)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		5 / 8 GLU A  73
HIS A   9
ASP A 192
HIS A 131
HIS A  40
 ZN  A 303 ( 2.3A)
ZN  A 302 (-3.3A)
ZN  A 302 (-2.6A)
ZN  A 303 (-3.4A)
ZN  A 301 (-3.2A)
 1.15A 1v7zE-1m68A:
undetectable		 1v7zE-1m68A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_F_CRNF7401_1
(CREATININE
AMIDOHYDROLASE)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		5 / 8 GLU A  73
HIS A   9
ASP A 192
HIS A 131
HIS A  40
 ZN  A 303 ( 2.3A)
ZN  A 302 (-3.3A)
ZN  A 302 (-2.6A)
ZN  A 303 (-3.4A)
ZN  A 301 (-3.2A)
 1.13A 1v7zF-1m68A:
undetectable		 1v7zF-1m68A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_B_RBFB301_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		5 / 12 ILE A 128
ALA A 188
GLY A 190
SER A 191
GLU A 156
 None
 1.27A 2a58A-1m68A:
undetectable
2a58B-1m68A:
undetectable		 2a58A-1m68A:
20.45
2a58B-1m68A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_E_RBFE304_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		5 / 12 ILE A 128
ALA A 188
GLY A 190
SER A 191
GLU A 156
 None
 1.27A 2a58D-1m68A:
undetectable
2a58E-1m68A:
undetectable		 2a58D-1m68A:
20.45
2a58E-1m68A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_F_HAEF3004_1
(COLLAGENASE 3)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		3 / 3 HIS A 194
HIS A  15
HIS A  40
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.1A)
ZN  A 301 (-3.2A)
 0.52A 2ozrF-1m68A:
undetectable		 2ozrF-1m68A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_B_CHDB504_0
(FERROCHELATASE)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		4 / 6 ILE A  96
PRO A  48
SER A  13
MET A  44
 None
 1.01A 2qd3B-1m68A:
undetectable		 2qd3B-1m68A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		5 / 11 HIS A   7
ILE A  97
HIS A 101
ASN A  75
HIS A  40
 ZN  A 302 (-3.2A)
None
ZN  A 303 (-3.2A)
None
ZN  A 301 (-3.2A)
 1.28A 2zweA-1m68A:
undetectable
2zweB-1m68A:
0.0		 2zweA-1m68A:
22.56
2zweB-1m68A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		5 / 11 HIS A   7
ILE A  97
HIS A 101
ASN A  75
HIS A  40
 ZN  A 302 (-3.2A)
None
ZN  A 303 (-3.2A)
None
ZN  A 301 (-3.2A)
 1.23A 2zwfA-1m68A:
undetectable
2zwfB-1m68A:
0.0		 2zwfA-1m68A:
22.56
2zwfB-1m68A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_A_CRNA303_1
(CREATININE
AMIDOHYDROLASE)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		5 / 8 GLU A  73
HIS A   9
ASP A 192
HIS A 131
HIS A  40
 ZN  A 303 ( 2.3A)
ZN  A 302 (-3.3A)
ZN  A 302 (-2.6A)
ZN  A 303 (-3.4A)
ZN  A 301 (-3.2A)
 1.14A 3a6jA-1m68A:
undetectable		 3a6jA-1m68A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_B_CRNB304_1
(CREATININE
AMIDOHYDROLASE)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		5 / 7 GLU A  73
HIS A   9
ASP A 192
HIS A 131
HIS A  40
 ZN  A 303 ( 2.3A)
ZN  A 302 (-3.3A)
ZN  A 302 (-2.6A)
ZN  A 303 (-3.4A)
ZN  A 301 (-3.2A)
 1.13A 3a6jB-1m68A:
undetectable		 3a6jB-1m68A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_C_CRNC305_1
(CREATININE
AMIDOHYDROLASE)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		5 / 8 GLU A  73
HIS A   9
ASP A 192
HIS A 131
HIS A  40
 ZN  A 303 ( 2.3A)
ZN  A 302 (-3.3A)
ZN  A 302 (-2.6A)
ZN  A 303 (-3.4A)
ZN  A 301 (-3.2A)
 1.12A 3a6jC-1m68A:
undetectable		 3a6jC-1m68A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_E_CRNE306_1
(CREATININE
AMIDOHYDROLASE)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		5 / 8 GLU A  73
HIS A   9
ASP A 192
HIS A 131
HIS A  40
 ZN  A 303 ( 2.3A)
ZN  A 302 (-3.3A)
ZN  A 302 (-2.6A)
ZN  A 303 (-3.4A)
ZN  A 301 (-3.2A)
 1.15A 3a6jE-1m68A:
undetectable		 3a6jE-1m68A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_F_CRNF307_1
(CREATININE
AMIDOHYDROLASE)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		5 / 8 GLU A  73
HIS A   9
ASP A 192
HIS A 131
HIS A  40
 ZN  A 303 ( 2.3A)
ZN  A 302 (-3.3A)
ZN  A 302 (-2.6A)
ZN  A 303 (-3.4A)
ZN  A 301 (-3.2A)
 1.11A 3a6jF-1m68A:
undetectable		 3a6jF-1m68A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID802_0
(GLUTAMATE RECEPTOR 2)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		3 / 3 SER A 193
ASP A   5
ASN A 221
 None
 0.95A 3lslA-1m68A:
undetectable
3lslD-1m68A:
undetectable		 3lslA-1m68A:
22.86
3lslD-1m68A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6A_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		4 / 6 PHE A 242
GLU A 232
MET A 236
ARG A  61
 None
 1.48A 3n6aA-1m68A:
0.0
3n6aB-1m68A:
0.0		 3n6aA-1m68A:
20.31
3n6aB-1m68A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ6_A_SAMA300_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		5 / 12 LEU A  95
ILE A  97
ILE A  72
ILE A 129
HIS A 127
 None
 0.95A 3uj6A-1m68A:
undetectable		 3uj6A-1m68A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1H_A_X8ZA305_1
(BETA-LACTAMASE 2)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		5 / 9 HIS A 131
ASP A 192
HIS A 101
GLY A  41
HIS A   9
 ZN  A 303 (-3.4A)
ZN  A 302 (-2.6A)
ZN  A 303 (-3.2A)
None
ZN  A 302 (-3.3A)
 1.24A 4c1hA-1m68A:
undetectable		 4c1hA-1m68A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EXS_B_X8ZB301_1
(BETA-LACTAMASE NDM-1)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		4 / 8 HIS A 131
ASP A 192
HIS A 101
HIS A   9
 ZN  A 303 (-3.4A)
ZN  A 302 (-2.6A)
ZN  A 303 (-3.2A)
ZN  A 302 (-3.3A)
 0.86A 4exsB-1m68A:
undetectable		 4exsB-1m68A:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H9M_A_HAEA929_1
(UREASE)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		5 / 5 HIS A   7
HIS A  40
HIS A 101
HIS A 131
ASP A 192
 ZN  A 302 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 303 (-3.2A)
ZN  A 303 (-3.4A)
ZN  A 302 (-2.6A)
 1.30A 4h9mA-1m68A:
3.7		 4h9mA-1m68A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		4 / 7 HIS A 101
HIS A 131
HIS A   7
HIS A   9
 ZN  A 303 (-3.2A)
ZN  A 303 (-3.4A)
ZN  A 302 (-3.2A)
ZN  A 302 (-3.3A)
 0.84A 4p6sA-1m68A:
undetectable		 4p6sA-1m68A:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_B_DAHB305_1
(TYROSINASE)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		4 / 7 HIS A 101
HIS A 131
HIS A   7
HIS A   9
 ZN  A 303 (-3.2A)
ZN  A 303 (-3.4A)
ZN  A 302 (-3.2A)
ZN  A 302 (-3.3A)
 0.78A 4p6sB-1m68A:
undetectable		 4p6sB-1m68A:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBP_C_HAEC800_1
(PROTEIN (UREASE
(CHAIN C)))		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		5 / 6 HIS A   7
HIS A   9
HIS A 101
HIS A 131
ASP A 192
 ZN  A 302 (-3.2A)
ZN  A 302 (-3.3A)
ZN  A 303 (-3.2A)
ZN  A 303 (-3.4A)
ZN  A 302 (-2.6A)
 1.04A 4ubpC-1m68A:
6.4		 4ubpC-1m68A:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A5Z_A_WJZA304_0
(BETA-LACTAMASE NDM-1)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		4 / 8 HIS A 131
ASP A 192
HIS A 101
HIS A   9
 ZN  A 303 (-3.4A)
ZN  A 302 (-2.6A)
ZN  A 303 (-3.2A)
ZN  A 302 (-3.3A)
 0.84A 5a5zA-1m68A:
undetectable		 5a5zA-1m68A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		3 / 3 PHE A  35
ILE A  37
ASP A 192
 None
None
ZN  A 302 (-2.6A)
 0.63A 5cswA-1m68A:
undetectable		 5cswA-1m68A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		3 / 3 PHE A  35
ILE A  37
ASP A 192
 None
None
ZN  A 302 (-2.6A)
 0.68A 5cswB-1m68A:
undetectable		 5cswB-1m68A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DWK_C_ACTC207_0
(DIACYLGLYCEROL
KINASE)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		4 / 5 GLU A 203
GLU A 204
ASN A 159
GLU A 201
 None
 1.41A 5dwkC-1m68A:
undetectable		 5dwkC-1m68A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		4 / 7 HIS A 101
HIS A 131
HIS A   7
HIS A   9
 ZN  A 303 (-3.2A)
ZN  A 303 (-3.4A)
ZN  A 302 (-3.2A)
ZN  A 302 (-3.3A)
 0.79A 5i3aA-1m68A:
undetectable		 5i3aA-1m68A:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		4 / 7 HIS A 101
HIS A 131
HIS A   7
HIS A   9
 ZN  A 303 (-3.2A)
ZN  A 303 (-3.4A)
ZN  A 302 (-3.2A)
ZN  A 302 (-3.3A)
 0.78A 5i3aB-1m68A:
undetectable		 5i3aB-1m68A:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_A_ACTA301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		4 / 6 ASP A 192
HIS A   9
HIS A 194
HIS A 131
 ZN  A 302 (-2.6A)
ZN  A 302 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 303 (-3.4A)
 0.87A 5ncdA-1m68A:
2.1
5ncdD-1m68A:
3.4		 5ncdA-1m68A:
22.02
5ncdD-1m68A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_C_ACTC301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		4 / 6 ASP A 192
HIS A   9
HIS A 194
HIS A 131
 ZN  A 302 (-2.6A)
ZN  A 302 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 303 (-3.4A)
 0.92A 5ncdB-1m68A:
3.4
5ncdC-1m68A:
3.5		 5ncdB-1m68A:
22.02
5ncdC-1m68A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		4 / 8 ASP A 192
HIS A   9
HIS A 194
HIS A 131
 ZN  A 302 (-2.6A)
ZN  A 302 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 303 (-3.4A)
 1.00A 5nekB-1m68A:
3.4		 5nekB-1m68A:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_A_ACTA302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		4 / 6 ASP A 192
HIS A   9
HIS A 194
HIS A 131
 ZN  A 302 (-2.6A)
ZN  A 302 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 303 (-3.4A)
 0.86A 5nelA-1m68A:
3.5
5nelD-1m68A:
3.5		 5nelA-1m68A:
22.02
5nelD-1m68A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		5 / 11 HIS A   7
ILE A  97
HIS A 101
ASN A  75
HIS A  40
 ZN  A 302 (-3.2A)
None
ZN  A 303 (-3.2A)
None
ZN  A 301 (-3.2A)
 1.24A 5z0gA-1m68A:
undetectable
5z0gB-1m68A:
0.0		 5z0gA-1m68A:
15.42
5z0gB-1m68A:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		5 / 11 HIS A   7
ILE A  97
HIS A 101
ASN A  75
HIS A  40
 ZN  A 302 (-3.2A)
None
ZN  A 303 (-3.2A)
None
ZN  A 301 (-3.2A)
 1.26A 5z0iA-1m68A:
undetectable
5z0iB-1m68A:
undetectable		 5z0iA-1m68A:
15.42
5z0iB-1m68A:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		5 / 11 HIS A   7
ILE A  97
HIS A 101
ASN A  75
HIS A  40
 ZN  A 302 (-3.2A)
None
ZN  A 303 (-3.2A)
None
ZN  A 301 (-3.2A)
 1.20A 5z0lA-1m68A:
undetectable
5z0lB-1m68A:
0.0		 5z0lA-1m68A:
15.42
5z0lB-1m68A:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		5 / 11 HIS A   7
ILE A  97
HIS A 101
ASN A  75
HIS A  40
 ZN  A 302 (-3.2A)
None
ZN  A 303 (-3.2A)
None
ZN  A 301 (-3.2A)
 1.24A 5z0mA-1m68A:
undetectable
5z0mB-1m68A:
0.0		 5z0mA-1m68A:
15.66
5z0mB-1m68A:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJ8_A_9DCA303_0
(METALLO-BETA-LACTAMA
SE TYPE 2)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		4 / 8 HIS A 131
ASP A 192
HIS A 101
HIS A   9
 ZN  A 303 (-3.4A)
ZN  A 302 (-2.6A)
ZN  A 303 (-3.2A)
ZN  A 302 (-3.3A)
 0.91A 5zj8A-1m68A:
undetectable		 5zj8A-1m68A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J21_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 1m68 HYPOTHETICAL PROTEIN
YCDX
(Escherichia
coli) 		5 / 12 ASN A 113
ILE A  76
VAL A 104
ILE A 139
HIS A 131
 None
None
None
None
ZN  A 303 (-3.4A)
 1.40A 6j21A-1m68A:
0.0		 6j21A-1m68A:
20.85