SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1m6z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_A_BEZA295_0
(CHLOROPEROXIDASE T)		 1m6z CYTOCHROME C4
(Pseudomonas
stutzeri) 		5 / 10 GLY A 103
PHE A 107
LEU A 174
THR A 146
LEU A 150
 None
None
None
HEC  A 200 ( 4.2A)
HEC  A 200 (-4.8A)
 1.03A 1a8uA-1m6zA:
undetectable		 1a8uA-1m6zA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_2
(POL POLYPROTEIN)		 1m6z CYTOCHROME C4
(Pseudomonas
stutzeri) 		3 / 3 ASP A  75
ILE A  47
VAL A  11
 None
 0.60A 2avvD-1m6zA:
undetectable		 2avvD-1m6zA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_2
(PROGESTERONE
RECEPTOR)		 1m6z CYTOCHROME C4
(Pseudomonas
stutzeri) 		4 / 7 LEU A  32
GLU A  37
LEU A  41
MET A  66
 HEC  A 199 (-4.7A)
None
None
HEC  A 199 (-2.3A)
 1.18A 2w8yA-1m6zA:
0.0		 2w8yA-1m6zA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_A_J01A500_1
(ORF12)		 1m6z CYTOCHROME C4
(Pseudomonas
stutzeri) 		4 / 8 ARG A 168
GLY A 169
ALA A 172
LYS A 173
 None
 0.94A 2xfsA-1m6zA:
undetectable		 2xfsA-1m6zA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_1
(METHYLTRANSFERASE
WBDD)		 1m6z CYTOCHROME C4
(Pseudomonas
stutzeri) 		3 / 3 GLN A 114
ASP A 178
GLN A 102
 None
 0.84A 4aztA-1m6zA:
undetectable		 4aztA-1m6zA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_B_SAMB501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 1m6z CYTOCHROME C4
(Pseudomonas
stutzeri) 		5 / 12 ALA A  82
GLY A   7
LYS A  10
ASP A  46
ASP A  77
 None
 1.17A 5wwsB-1m6zA:
undetectable		 5wwsB-1m6zA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA604_0
(SERUM ALBUMIN)		 1m6z CYTOCHROME C4
(Pseudomonas
stutzeri) 		4 / 8 GLY A 188
ALA A 100
LYS A 101
GLU A 104
 None
 0.52A 6mdqA-1m6zA:
undetectable		 6mdqA-1m6zA:
23.08