SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1m72'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ILP_C_ACAC7_1
(PROTEIN
(INTERLEUKIN-8
PRECURSOR)
PROTEIN
(INTERLEUKIN-8
RECEPTOR))		 1m72 CASPASE-1
(Spodoptera
frugiperda) 		4 / 5 PRO A  45
HIS A  57
ASP A 127
MET A  55
 None
 1.35A 1ilpA-1m72A:
0.0
1ilpC-1m72A:
undetectable		 1ilpA-1m72A:
13.72
1ilpC-1m72A:
7.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1873_0
(FPRA)		 1m72 CASPASE-1
(Spodoptera
frugiperda) 		3 / 3 ASP A 125
ASP A 122
LYS A 169
 None
 1.16A 1lqtB-1m72A:
undetectable		 1lqtB-1m72A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1430_0
(FPRA)		 1m72 CASPASE-1
(Spodoptera
frugiperda) 		3 / 3 ASP A 125
ASP A 122
LYS A 169
 None
 1.13A 1lquB-1m72A:
undetectable		 1lquB-1m72A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_D_BEZD2385_0
(CES1 PROTEIN)		 1m72 CASPASE-1
(Spodoptera
frugiperda) 		4 / 5 LEU A 236
LEU A 252
LEU A 250
LEU A 240
 None
 0.95A 1yajD-1m72A:
3.2		 1yajD-1m72A:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 1m72 CASPASE-1
(Spodoptera
frugiperda) 		5 / 12 LEU A 154
LEU A 172
MET A 233
LEU A 134
PHE A 214
 None
 1.35A 2oaxA-1m72A:
undetectable		 2oaxA-1m72A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1m72 CASPASE-1
(Spodoptera
frugiperda) 		4 / 4 SER A 230
GLY A 229
HIS A  68
ASP A  72
 None
 1.37A 2oxtC-1m72A:
undetectable		 2oxtC-1m72A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_0
(PUTATIVE
MODIFICATION
METHYLASE)		 1m72 CASPASE-1
(Spodoptera
frugiperda) 		5 / 12 ALA A 126
ALA A 208
PHE A 210
GLY A 168
VAL A  46
 None
 1.14A 2zifB-1m72A:
undetectable		 2zifB-1m72A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AVO_A_PAUA314_0
(PANTOTHENATE KINASE)		 1m72 CASPASE-1
(Spodoptera
frugiperda) 		5 / 11 VAL A 131
LEU A 142
TYR A 149
PHE A 232
ILE A 212
 None
 1.42A 3avoA-1m72A:
0.0		 3avoA-1m72A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1m72 CASPASE-1
(Spodoptera
frugiperda) 		4 / 5 ILE A  65
THR A 118
PHE A 158
PHE A 173
 None
 1.30A 3em0A-1m72A:
0.0		 3em0A-1m72A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ITA_D_AICD501_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC)		 1m72 CASPASE-1
(Spodoptera
frugiperda) 		3 / 3 PRO A 281
PHE A 264
ALA A 235
 None
 0.72A 3itaD-1m72A:
0.0		 3itaD-1m72A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_C_OBNC1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1m72 CASPASE-1
(Spodoptera
frugiperda) 		5 / 11 LEU A 142
VAL A 133
ALA A 132
PHE A 173
PHE A 210
 None
 1.33A 3n23C-1m72A:
2.3		 3n23C-1m72A:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_B_MIYB2001_1
(TETX2 PROTEIN)		 1m72 CASPASE-1
(Spodoptera
frugiperda) 		4 / 8 ARG A  79
HIS A  70
GLY A 229
ASN A  88
 None
 0.98A 3v3nB-1m72A:
3.8		 3v3nB-1m72A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_C_MIYC2001_1
(TETX2 PROTEIN)		 1m72 CASPASE-1
(Spodoptera
frugiperda) 		4 / 8 ARG A  79
HIS A  70
GLY A 229
ASN A  88
 None
 0.98A 3v3nC-1m72A:
3.5		 3v3nC-1m72A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 1m72 CASPASE-1
(Spodoptera
frugiperda) 		5 / 12 VAL A 131
THR A 159
ILE A 115
PHE A 158
TRP A 155
 None
 1.21A 4c49C-1m72A:
0.0		 4c49C-1m72A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1m72 CASPASE-1
(Spodoptera
frugiperda) 		4 / 7 ASN A 112
GLU A 110
ILE A 111
ASP A 146
 None
 1.12A 4d39B-1m72A:
0.0		 4d39B-1m72A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_A_NCTA501_1
(CYTOCHROME P450 2A6)		 1m72 CASPASE-1
(Spodoptera
frugiperda) 		4 / 7 PHE A 173
PHE A 158
THR A 118
ILE A 115
 None
 0.78A 4ejjA-1m72A:
undetectable		 4ejjA-1m72A:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_B_SALB602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 1m72 CASPASE-1
(Spodoptera
frugiperda) 		4 / 7 LEU A 166
THR A 118
ILE A  64
GLY A  61
 None
 0.91A 4eqlB-1m72A:
1.8		 4eqlB-1m72A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_2
(ANDROGEN RECEPTOR)		 1m72 CASPASE-1
(Spodoptera
frugiperda) 		4 / 8 LEU A 240
MET A  55
LEU A 291
ILE A 212
 None
 0.98A 4ok1A-1m72A:
undetectable		 4ok1A-1m72A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1m72 CASPASE-1
(Spodoptera
frugiperda) 		3 / 3 THR A  82
HIS A 148
LEU A  76
 None
 0.80A 5axdA-1m72A:
4.1		 5axdA-1m72A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_C_RBVC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1m72 CASPASE-1
(Spodoptera
frugiperda) 		3 / 3 THR A  82
HIS A 148
LEU A  76
 None
 0.82A 5axdC-1m72A:
3.0		 5axdC-1m72A:
19.05