SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1m7h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMA_A_SAMA105_0
(PROTEIN (MET
REPRESSOR))		 1m7h ADENYLYLSULFATE
KINASE
(Penicillium
chrysogenum) 		4 / 8 GLU A  82
ARG A  85
ARG A  86
LEU A  73
 None
 0.85A 1cmaA-1m7hA:
undetectable
1cmaB-1m7hA:
undetectable		 1cmaA-1m7hA:
19.51
1cmaB-1m7hA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NNC_A_ZMRA479_2
(NEURAMINIDASE N9)		 1m7h ADENYLYLSULFATE
KINASE
(Penicillium
chrysogenum) 		4 / 4 ASP A 112
ARG A 113
TRP A  29
ILE A  87
 None
 1.50A 1nncA-1m7hA:
undetectable		 1nncA-1m7hA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 1m7h ADENYLYLSULFATE
KINASE
(Penicillium
chrysogenum) 		5 / 12 PHE A 133
ALA A  91
ALA A  95
ALA A 116
TYR A 199
 None
 1.26A 2igtC-1m7hA:
undetectable		 2igtC-1m7hA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_A_X2NA1480_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 1m7h ADENYLYLSULFATE
KINASE
(Penicillium
chrysogenum) 		5 / 12 TYR A 205
PRO A 207
ALA A 208
ALA A 101
ALA A  95
 None
 1.04A 2x2nA-1m7hA:
undetectable		 2x2nA-1m7hA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_C_DX2C270_1
(PTERIDINE REDUCTASE
1)		 1m7h ADENYLYLSULFATE
KINASE
(Penicillium
chrysogenum) 		4 / 8 SER A 107
PHE A 105
VAL A  90
LEU A  69
 None
SO4  A1002 (-4.8A)
None
None
 1.13A 3jq7C-1m7hA:
5.2		 3jq7C-1m7hA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REM_A_SALA301_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 1m7h ADENYLYLSULFATE
KINASE
(Penicillium
chrysogenum) 		4 / 8 VAL A 134
VAL A 182
TYR A 199
ILE A 196
 None
 0.98A 3remA-1m7hA:
undetectable		 3remA-1m7hA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REM_B_SALB301_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 1m7h ADENYLYLSULFATE
KINASE
(Penicillium
chrysogenum) 		4 / 8 VAL A 134
VAL A 182
TYR A 199
ILE A 196
 None
 0.98A 3remB-1m7hA:
undetectable		 3remB-1m7hA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SAN_A_ZMRA901_2
(NEURAMINIDASE)		 1m7h ADENYLYLSULFATE
KINASE
(Penicillium
chrysogenum) 		4 / 5 ASP A 112
ARG A 113
TRP A  29
ILE A  87
 None
 1.48A 3sanA-1m7hA:
undetectable		 3sanA-1m7hA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SAN_B_ZMRB901_2
(NEURAMINIDASE)		 1m7h ADENYLYLSULFATE
KINASE
(Penicillium
chrysogenum) 		4 / 5 ASP A 112
ARG A 113
TRP A  29
ILE A  87
 None
 1.49A 3sanB-1m7hA:
undetectable		 3sanB-1m7hA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_B_STRB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1m7h ADENYLYLSULFATE
KINASE
(Penicillium
chrysogenum) 		4 / 6 VAL A 180
VAL A 134
ILE A  28
LEU A  41
 None
 0.97A 4l1wB-1m7hA:
undetectable		 4l1wB-1m7hA:
20.73