SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1m7s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2434_1
(CHITINASE)		 1m7s CATALASE
(Pseudomonas
syringae) 		4 / 6 GLU A 462
ASP A 181
PHE A 185
ARG A 184
 None
 1.44A 2a3bB-1m7sA:
undetectable		 2a3bB-1m7sA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA702_0
(FERROCHELATASE)		 1m7s CATALASE
(Pseudomonas
syringae) 		4 / 7 MET A 214
ARG A  80
PRO A 277
VAL A  84
 None
 1.38A 2hrcA-1m7sA:
undetectable		 2hrcA-1m7sA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 1m7s CATALASE
(Pseudomonas
syringae) 		4 / 8 SER A 261
VAL A 268
TYR A 260
PHE A 325
 None
 1.18A 2wekA-1m7sA:
undetectable		 2wekA-1m7sA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 1m7s CATALASE
(Pseudomonas
syringae) 		4 / 8 SER A 261
VAL A 268
TYR A 260
PHE A 325
 None
 1.14A 2wekB-1m7sA:
undetectable		 2wekB-1m7sA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 1m7s CATALASE
(Pseudomonas
syringae) 		5 / 12 TYR A 139
GLY A 370
GLY A 367
ALA A 390
VAL A 375
 None
 1.12A 2zulA-1m7sA:
undetectable		 2zulA-1m7sA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_1
(CYTOCHROME P450 2R1)		 1m7s CATALASE
(Pseudomonas
syringae) 		4 / 5 ASN A 386
ALA A 359
LEU A 366
GLY A 370
 None
 0.87A 3dl9A-1m7sA:
0.0		 3dl9A-1m7sA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMF_A_SAMA388_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 1m7s CATALASE
(Pseudomonas
syringae) 		5 / 12 TYR A 139
GLY A 370
GLY A 367
ALA A 390
VAL A 375
 None
 1.12A 3dmfA-1m7sA:
undetectable		 3dmfA-1m7sA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA310_1
(BETA-LACTAMASE)		 1m7s CATALASE
(Pseudomonas
syringae) 		5 / 8 LEU A 263
ARG A  80
ALA A  79
GLY A 206
PRO A 208
 None
 1.19A 3ny4A-1m7sA:
undetectable		 3ny4A-1m7sA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_A_CAMA1419_0
(CYTOCHROME P450)		 1m7s CATALASE
(Pseudomonas
syringae) 		4 / 8 THR A 199
LEU A 476
LEU A 479
GLY A 487
 None
 0.85A 4c9nA-1m7sA:
undetectable		 4c9nA-1m7sA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAJ_B_ACAB512_1
(HIV-1 YU2 GP120
ENVELOPE
GLYCOPROTEIN)		 1m7s CATALASE
(Pseudomonas
syringae) 		4 / 6 GLY A 149
ASP A 146
PRO A 336
ARG A 354
 HEM  A 600 (-4.0A)
None
None
HEM  A 600 (-3.5A)
 1.11A 4lajA-1m7sA:
undetectable
4lajB-1m7sA:
0.0		 4lajA-1m7sA:
20.24
4lajB-1m7sA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAJ_B_ACAB512_1
(HIV-1 YU2 GP120
ENVELOPE
GLYCOPROTEIN)		 1m7s CATALASE
(Pseudomonas
syringae) 		4 / 6 GLY A 218
ASP A 146
PRO A 336
ARG A 354
 None
None
None
HEM  A 600 (-3.5A)
 0.99A 4lajA-1m7sA:
undetectable
4lajB-1m7sA:
0.0		 4lajA-1m7sA:
20.24
4lajB-1m7sA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_2
(NUPC FAMILY PROTEIN)		 1m7s CATALASE
(Pseudomonas
syringae) 		3 / 3 THR A 264
ASN A 324
PHE A 326
 None
 0.84A 4pd9A-1m7sA:
undetectable		 4pd9A-1m7sA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 1m7s CATALASE
(Pseudomonas
syringae) 		5 / 12 ASP A 215
ASN A 217
PHE A 138
PHE A 134
GLY A 149
 None
None
None
None
HEM  A 600 (-4.0A)
 1.26A 4pevA-1m7sA:
undetectable		 4pevA-1m7sA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 1m7s CATALASE
(Pseudomonas
syringae) 		5 / 12 ASP A 215
ASN A 217
PHE A 138
PHE A 134
GLY A 149
 None
None
None
None
HEM  A 600 (-4.0A)
 1.24A 4pevB-1m7sA:
0.0		 4pevB-1m7sA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 1m7s CATALASE
(Pseudomonas
syringae) 		5 / 12 ASP A 215
ASN A 217
PHE A 138
PHE A 134
GLY A 149
 None
None
None
None
HEM  A 600 (-4.0A)
 1.25A 4pevC-1m7sA:
undetectable		 4pevC-1m7sA:
23.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QOP_A_HQEA503_1
(CATALASE)		 1m7s CATALASE
(Pseudomonas
syringae) 		5 / 9 ASP A 130
PRO A 131
PHE A 156
LEU A 201
ASP A 181
 None
 0.83A 4qopA-1m7sA:
56.1		 4qopA-1m7sA:
49.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QOP_B_HQEB503_1
(CATALASE)		 1m7s CATALASE
(Pseudomonas
syringae) 		5 / 9 ASP A 130
PRO A 131
PHE A 156
LEU A 201
ASP A 181
 None
 0.83A 4qopB-1m7sA:
55.9		 4qopB-1m7sA:
49.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QOP_C_HQEC503_1
(CATALASE)		 1m7s CATALASE
(Pseudomonas
syringae) 		4 / 8 ASP A 130
PRO A 131
PHE A 156
LEU A 201
 None
 0.60A 4qopC-1m7sA:
55.9		 4qopC-1m7sA:
49.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A5Z_C_WJZC304_0
(BETA-LACTAMASE NDM-1)		 1m7s CATALASE
(Pseudomonas
syringae) 		4 / 7 MET A 214
HIS A  78
GLY A 149
ASN A 150
 None
HEM  A 600 (-3.3A)
HEM  A 600 (-4.0A)
HEM  A 600 (-3.4A)
 1.31A 5a5zC-1m7sA:
undetectable		 5a5zC-1m7sA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H8T_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 1m7s CATALASE
(Pseudomonas
syringae) 		4 / 6 LEU A 350
LYS A 303
THR A 302
GLN A 436
 HEM  A 600 (-4.2A)
None
None
None
 1.30A 5h8tA-1m7sA:
2.7		 5h8tA-1m7sA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_1
(CDL2.3A)		 1m7s CATALASE
(Pseudomonas
syringae) 		5 / 12 LEU A 464
TYR A 486
PHE A 185
PHE A 188
ALA A 194
 None
 1.35A 5ieoA-1m7sA:
undetectable		 5ieoA-1m7sA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M10_A_NCAA603_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 1m7s CATALASE
(Pseudomonas
syringae) 		4 / 5 LEU A 147
PHE A 103
LEU A 281
TRP A 145
 None
 1.30A 5m10A-1m7sA:
undetectable		 5m10A-1m7sA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_1
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 1m7s CATALASE
(Pseudomonas
syringae) 		3 / 3 THR A 264
GLU A 126
HIS A 123
 None
 0.76A 5xioA-1m7sA:
undetectable		 5xioA-1m7sA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_B_HFGB1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 1m7s CATALASE
(Pseudomonas
syringae) 		3 / 3 THR A 264
GLU A 126
HIS A 123
 None
 0.76A 5xiqB-1m7sA:
undetectable		 5xiqB-1m7sA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 1m7s CATALASE
(Pseudomonas
syringae) 		3 / 3 THR A 264
GLU A 126
HIS A 123
 None
 0.74A 5xiqD-1m7sA:
undetectable		 5xiqD-1m7sA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 1m7s CATALASE
(Pseudomonas
syringae) 		4 / 8 TYR A 139
VAL A 375
ASN A 376
ASN A 338
 None
 1.11A 6hzpA-1m7sA:
undetectable		 6hzpA-1m7sA:
22.71