SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1m8r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 1m8r PHOSPHOLIPASE A2
(Gloydius
halys) 		4 / 8 LEU A   2
GLY A  30
HIS A  48
PHE A 106
 None
BU1  A1002 (-4.3A)
None
None
 0.79A 1sv9A-1m8rA:
20.9		 1sv9A-1m8rA:
54.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 1m8r PHOSPHOLIPASE A2
(Gloydius
halys) 		4 / 7 GLY A  30
HIS A  48
ASP A  49
TYR A  52
 BU1  A1002 (-4.3A)
None
CD  A1001 (-2.4A)
None
 0.44A 1th6A-1m8rA:
21.0		 1th6A-1m8rA:
54.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 1m8r PHOSPHOLIPASE A2
(Gloydius
halys) 		4 / 7 GLY A  32
HIS A  48
TYR A  52
PRO A  68
 CD  A1001 (-3.9A)
None
None
None
 0.94A 1th6A-1m8rA:
21.0		 1th6A-1m8rA:
54.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 1m8r PHOSPHOLIPASE A2
(Gloydius
halys) 		4 / 7 HIS A  48
ASP A  49
TYR A  52
PRO A  68
 None
CD  A1001 (-2.4A)
None
None
 0.36A 1th6A-1m8rA:
21.0		 1th6A-1m8rA:
54.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Y4L_B_SVRB301_1
(PHOSPHOLIPASE A2
HOMOLOG 2)		 1m8r PHOSPHOLIPASE A2
(Gloydius
halys) 		5 / 12 LEU A   2
GLY A  30
GLY A  32
TYR A  52
PRO A  68
 None
BU1  A1002 (-4.3A)
CD  A1001 (-3.9A)
None
None
 1.25A 1y4lA-1m8rA:
19.8		 1y4lA-1m8rA:
50.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1m8r PHOSPHOLIPASE A2
(Gloydius
halys) 		4 / 7 GLY A  30
HIS A  48
ASP A  49
TYR A  52
 BU1  A1002 (-4.3A)
None
CD  A1001 (-2.4A)
None
 0.45A 2armA-1m8rA:
21.0		 2armA-1m8rA:
54.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1m8r PHOSPHOLIPASE A2
(Gloydius
halys) 		4 / 7 GLY A  32
HIS A  48
TYR A  52
PRO A  68
 CD  A1001 (-3.9A)
None
None
None
 0.97A 2armA-1m8rA:
21.0		 2armA-1m8rA:
54.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1m8r PHOSPHOLIPASE A2
(Gloydius
halys) 		4 / 7 HIS A  48
ASP A  49
TYR A  52
PRO A  68
 None
CD  A1001 (-2.4A)
None
None
 0.38A 2armA-1m8rA:
21.0		 2armA-1m8rA:
54.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2B17_A_DIFA701_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1m8r PHOSPHOLIPASE A2
(Gloydius
halys) 		5 / 10 LEU A   2
GLY A  30
HIS A  48
ASP A  49
PHE A 106
 None
BU1  A1002 (-4.3A)
None
CD  A1001 (-2.4A)
None
 0.75A 2b17A-1m8rA:
20.9		 2b17A-1m8rA:
54.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1m8r PHOSPHOLIPASE A2
(Gloydius
halys) 		4 / 6 LEU A   2
HIS A  48
ASP A  49
TYR A  52
 None
None
CD  A1001 (-2.4A)
None
 0.59A 2dpzA-1m8rA:
20.9		 2dpzA-1m8rA:
54.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OTF_A_2TNA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1m8r PHOSPHOLIPASE A2
(Gloydius
halys) 		4 / 5 LEU A   2
SER A  23
GLY A  30
HIS A  48
 None
BU1  A1003 (-3.0A)
BU1  A1002 (-4.3A)
None
 0.68A 2otfA-1m8rA:
21.0		 2otfA-1m8rA:
54.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FO7_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1m8r PHOSPHOLIPASE A2
(Gloydius
halys) 		4 / 5 HIS A  48
ASP A  49
TYR A  52
PRO A  68
 None
CD  A1001 (-2.4A)
None
None
 0.38A 3fo7A-1m8rA:
20.9		 3fo7A-1m8rA:
54.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H1X_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1m8r PHOSPHOLIPASE A2
(Gloydius
halys) 		4 / 5 HIS A  48
ASP A  49
TYR A  52
PRO A  68
 None
CD  A1001 (-2.4A)
None
None
 0.44A 3h1xA-1m8rA:
20.9		 3h1xA-1m8rA:
54.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OSH_A_OINA5811_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 1m8r PHOSPHOLIPASE A2
(Gloydius
halys) 		5 / 9 LEU A   2
PHE A   5
ILE A   9
GLY A  30
HIS A  48
 None
BU1  A1002 ( 4.8A)
None
BU1  A1002 (-4.3A)
None
 0.67A 3oshA-1m8rA:
17.2		 3oshA-1m8rA:
38.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_B_DM5B602_1
(SERUM ALBUMIN)		 1m8r PHOSPHOLIPASE A2
(Gloydius
halys) 		5 / 9 VAL A  47
ALA A 102
PHE A 106
TYR A 113
TYR A  25
 None
 1.48A 4lb2B-1m8rA:
2.0		 4lb2B-1m8rA:
11.90