SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1m8u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_C_CRNC4401_1
(CREATININE
AMIDOHYDROLASE)		 1m8u GAMMA-E
(Bos
taurus) 		4 / 8 HIS A 113
HIS A 122
TYR A 154
TRP A 157
 None
 0.95A 1v7zC-1m8uA:
undetectable		 1v7zC-1m8uA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_F_CRNF7401_1
(CREATININE
AMIDOHYDROLASE)		 1m8u GAMMA-E
(Bos
taurus) 		4 / 8 HIS A 113
HIS A 122
TYR A 154
TRP A 157
 None
 0.97A 1v7zF-1m8uA:
undetectable		 1v7zF-1m8uA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_A_EAAA222_1
(GLUTATHIONE
S-TRANSFERASE P)		 1m8u GAMMA-E
(Bos
taurus) 		5 / 10 TYR A 151
VAL A 126
GLY A 149
VAL A 132
GLN A 143
 None
 1.28A 3km6A-1m8uA:
undetectable		 3km6A-1m8uA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_A_EAAA214_1
(GLUTATHIONE
S-TRANSFERASE P)		 1m8u GAMMA-E
(Bos
taurus) 		5 / 9 TYR A 151
VAL A 126
GLY A 149
VAL A 132
GLN A 143
 None
 1.31A 3kmoA-1m8uA:
undetectable		 3kmoA-1m8uA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1m8u GAMMA-E
(Bos
taurus) 		3 / 3 SER A  20
HIS A  22
TYR A  16
 None
 0.92A 5y2tA-1m8uA:
undetectable		 5y2tA-1m8uA:
undetectable