SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1m93'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 1m93 SERINE PROTEINASE
INHIBITOR 2
SERINE PROTEINASE
INHIBITOR 2
(Cowpox
virus;
Cowpox
virus) 		5 / 11 VAL B 198
PHE C 318
THR B 291
ILE B 284
PHE B 238
 None
 0.95A 1z11A-1m93B:
0.0		 1z11A-1m93B:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 1m93 SERINE PROTEINASE
INHIBITOR 2
SERINE PROTEINASE
INHIBITOR 2
(Cowpox
virus;
Cowpox
virus) 		5 / 11 VAL B 198
PHE C 318
THR B 291
ILE B 284
PHE B 238
 None
 0.93A 1z11B-1m93B:
0.0		 1z11B-1m93B:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_B_DVAB6_0
(GRAMICIDIN D)		 1m93 SERINE PROTEINASE
INHIBITOR 2
(Cowpox
virus) 		3 / 3 TRP B 137
ALA B 293
VAL B 286
 None
 0.85A 2izqA-1m93B:
undetectable
2izqB-1m93B:
undetectable		 2izqA-1m93B:
6.79
2izqB-1m93B:
6.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA802_1
(PROSTAGLANDIN
REDUCTASE 1)		 1m93 SERINE PROTEINASE
INHIBITOR 2
(Cowpox
virus) 		4 / 7 VAL B 273
TYR B 265
ASN B 267
ASP B  75
 None
 0.96A 2y05A-1m93B:
undetectable
2y05B-1m93B:
undetectable		 2y05A-1m93B:
22.19
2y05B-1m93B:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBP_A_SAMA300_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1m93 SERINE PROTEINASE
INHIBITOR 2
(Cowpox
virus) 		5 / 12 LEU B 300
GLY B  67
ILE B 128
SER B 298
LEU B 119
 None
 1.02A 2zbpA-1m93B:
undetectable		 2zbpA-1m93B:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1m93 SERINE PROTEINASE
INHIBITOR 2
SERINE PROTEINASE
INHIBITOR 2
(Cowpox
virus;
Cowpox
virus) 		5 / 10 TYR B 244
GLY B 242
PHE A  17
VAL B 131
LEU B 246
 None
 1.33A 3elzB-1m93B:
undetectable		 3elzB-1m93B:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_B_9PLB501_1
(CYTOCHROME P450 2A6)		 1m93 SERINE PROTEINASE
INHIBITOR 2
(Cowpox
virus) 		5 / 10 VAL B 198
PHE C 318
THR B 291
ILE B 284
PHE B 238
 None
 0.94A 3t3qB-1m93B:
undetectable		 3t3qB-1m93B:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_C_9PLC501_1
(CYTOCHROME P450 2A6)		 1m93 SERINE PROTEINASE
INHIBITOR 2
(Cowpox
virus) 		5 / 10 VAL B 198
PHE C 318
THR B 291
ILE B 284
PHE B 238
 None
 0.92A 3t3qC-1m93B:
undetectable		 3t3qC-1m93B:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_D_9PLD501_1
(CYTOCHROME P450 2A6)		 1m93 SERINE PROTEINASE
INHIBITOR 2
(Cowpox
virus) 		5 / 10 VAL B 198
PHE C 318
THR B 291
ILE B 284
PHE B 238
 None
 0.93A 3t3qD-1m93B:
undetectable		 3t3qD-1m93B:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA2_1
(CYTOCHROME P450 2D6)		 1m93 SERINE PROTEINASE
INHIBITOR 2
(Cowpox
virus) 		5 / 11 THR B  95
VAL B  88
SER B 298
LEU B 125
THR B 123
 None
 1.34A 3tbgA-1m93B:
undetectable		 3tbgA-1m93B:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1m93 SERINE PROTEINASE
INHIBITOR 2
SERINE PROTEINASE
INHIBITOR 2
(Cowpox
virus;
Cowpox
virus) 		5 / 11 ILE A  18
ILE A  23
VAL A  26
LEU A  27
VAL B 258
 None
 0.94A 3w67A-1m93A:
undetectable		 3w67A-1m93A:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PUO_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 1m93 SERINE PROTEINASE
INHIBITOR 2
(Cowpox
virus) 		4 / 8 LEU A  27
VAL B 258
LEU B 250
TYR A  45
 None
 1.05A 4puoC-1m93A:
undetectable		 4puoC-1m93A:
7.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		 1m93 SERINE PROTEINASE
INHIBITOR 2
(Cowpox
virus) 		4 / 6 ASP B 216
LEU B 214
ILE A  18
PHE A   4
 PO4  A 401 (-3.1A)
None
None
None
 1.20A 4y4dA-1m93B:
0.0		 4y4dA-1m93B:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_W_BEZW801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1m93 SERINE PROTEINASE
INHIBITOR 2
SERINE PROTEINASE
INHIBITOR 2
(Cowpox
virus;
Cowpox
virus) 		5 / 5 PHE B  77
ILE A  29
GLY A  33
ILE B  81
LEU A  30
 None
 1.49A 5dzkB-1m93B:
undetectable
5dzkI-1m93B:
undetectable
5dzkW-1m93B:
undetectable		 5dzkB-1m93B:
23.32
5dzkI-1m93B:
22.57
5dzkW-1m93B:
0.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUJ_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 1m93 SERINE PROTEINASE
INHIBITOR 2
(Cowpox
virus) 		4 / 8 PHE B 219
LEU B 214
ILE B 185
VAL B 197
 None
 0.83A 5nujA-1m93B:
0.6		 5nujA-1m93B:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DHB_A_BEZA202_0
(HEPATITIS A VIRUS
CELLULAR RECEPTOR 2)		 1m93 SERINE PROTEINASE
INHIBITOR 2
(Cowpox
virus) 		4 / 6 ARG B  94
ILE B  99
ASN B 100
ASP B  97
 None
 1.29A 6dhbA-1m93B:
0.0		 6dhbA-1m93B:
20.00