SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1m9q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.32A 1c9sA-1m9qA:
0.0
1c9sK-1m9qA:
undetectable		 1c9sA-1m9qA:
9.88
1c9sK-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.31A 1c9sA-1m9qA:
0.0
1c9sB-1m9qA:
undetectable		 1c9sA-1m9qA:
9.88
1c9sB-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.31A 1c9sB-1m9qA:
undetectable
1c9sC-1m9qA:
undetectable		 1c9sB-1m9qA:
9.88
1c9sC-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.35A 1c9sC-1m9qA:
undetectable
1c9sD-1m9qA:
0.0		 1c9sC-1m9qA:
9.88
1c9sD-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.30A 1c9sD-1m9qA:
0.0
1c9sE-1m9qA:
undetectable		 1c9sD-1m9qA:
9.88
1c9sE-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.32A 1c9sE-1m9qA:
undetectable
1c9sF-1m9qA:
0.0		 1c9sE-1m9qA:
9.88
1c9sF-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.34A 1c9sF-1m9qA:
0.0
1c9sG-1m9qA:
0.0		 1c9sF-1m9qA:
9.88
1c9sG-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.32A 1c9sG-1m9qA:
0.0
1c9sH-1m9qA:
undetectable		 1c9sG-1m9qA:
9.88
1c9sH-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.35A 1c9sH-1m9qA:
undetectable
1c9sI-1m9qA:
undetectable		 1c9sH-1m9qA:
9.88
1c9sI-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.34A 1c9sJ-1m9qA:
undetectable
1c9sK-1m9qA:
undetectable		 1c9sJ-1m9qA:
9.88
1c9sK-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.34A 1c9sL-1m9qA:
0.0
1c9sM-1m9qA:
0.0		 1c9sL-1m9qA:
9.88
1c9sM-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 1c9sM-1m9qA:
0.0
1c9sN-1m9qA:
0.0		 1c9sM-1m9qA:
9.88
1c9sN-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.35A 1c9sO-1m9qA:
0.0
1c9sP-1m9qA:
0.0		 1c9sO-1m9qA:
9.88
1c9sP-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.35A 1c9sS-1m9qA:
0.0
1c9sT-1m9qA:
0.0		 1c9sS-1m9qA:
9.88
1c9sT-1m9qA:
9.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMI_A_BHSA1610_1
(NITRIC OXIDE
SYNTHASE)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 8 SER A 102
VAL A 104
ARG A 365
ALA A 446
TRP A 447
 None
MPD  A 605 (-4.7A)
MPD  A 605 ( 4.7A)
MPD  A 605 (-3.5A)
MPD  A 605 ( 4.0A)
 0.35A 1dmiA-1m9qA:
60.9
1dmiB-1m9qA:
60.8		 1dmiA-1m9qA:
95.17
1dmiB-1m9qA:
95.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.32A 1gtfA-1m9qA:
undetectable
1gtfK-1m9qA:
undetectable		 1gtfA-1m9qA:
9.88
1gtfK-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.32A 1gtfA-1m9qA:
undetectable
1gtfB-1m9qA:
undetectable		 1gtfA-1m9qA:
9.88
1gtfB-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.33A 1gtfB-1m9qA:
undetectable
1gtfC-1m9qA:
undetectable		 1gtfB-1m9qA:
9.88
1gtfC-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.33A 1gtfC-1m9qA:
undetectable
1gtfD-1m9qA:
undetectable		 1gtfC-1m9qA:
9.88
1gtfD-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.30A 1gtfE-1m9qA:
0.0
1gtfF-1m9qA:
0.0		 1gtfE-1m9qA:
9.88
1gtfF-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.33A 1gtfF-1m9qA:
0.0
1gtfG-1m9qA:
undetectable		 1gtfF-1m9qA:
9.88
1gtfG-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.32A 1gtfG-1m9qA:
undetectable
1gtfH-1m9qA:
undetectable		 1gtfG-1m9qA:
9.88
1gtfH-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.30A 1gtfH-1m9qA:
undetectable
1gtfI-1m9qA:
undetectable		 1gtfH-1m9qA:
9.88
1gtfI-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.34A 1gtfI-1m9qA:
undetectable
1gtfJ-1m9qA:
undetectable		 1gtfI-1m9qA:
9.88
1gtfJ-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 1gtfO-1m9qA:
0.0
1gtfP-1m9qA:
0.0		 1gtfO-1m9qA:
9.88
1gtfP-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.35A 1gtfP-1m9qA:
0.0
1gtfQ-1m9qA:
0.0		 1gtfP-1m9qA:
9.88
1gtfQ-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 1gtfT-1m9qA:
0.0
1gtfU-1m9qA:
0.0		 1gtfT-1m9qA:
9.88
1gtfU-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 11 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.33A 1gtfU-1m9qA:
0.0
1gtfV-1m9qA:
0.0		 1gtfU-1m9qA:
9.88
1gtfV-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.34A 1gtfL-1m9qA:
0.0
1gtfV-1m9qA:
0.0		 1gtfL-1m9qA:
9.88
1gtfV-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 8 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.33A 1gtnA-1m9qA:
undetectable
1gtnB-1m9qA:
undetectable		 1gtnA-1m9qA:
9.88
1gtnB-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 1gtnN-1m9qA:
undetectable
1gtnO-1m9qA:
undetectable		 1gtnN-1m9qA:
9.88
1gtnO-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.35A 1gtnR-1m9qA:
0.0
1gtnS-1m9qA:
0.0		 1gtnR-1m9qA:
9.88
1gtnS-1m9qA:
9.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M8D_A_CLWA906_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 5 PRO A 334
VAL A 336
TYR A 357
MET A 358
GLU A 361
 5NI  A 907 ( 4.8A)
5NI  A 907 (-4.4A)
5NI  A 907 (-4.6A)
HEM  A 901 ( 4.4A)
HEM  A 901 ( 3.1A)
 0.40A 1m8dA-1m9qA:
55.6		 1m8dA-1m9qA:
61.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M8D_B_CLWB907_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 5 PRO A 334
VAL A 336
TYR A 357
MET A 358
GLU A 361
 5NI  A 907 ( 4.8A)
5NI  A 907 (-4.4A)
5NI  A 907 (-4.6A)
HEM  A 901 ( 4.4A)
HEM  A 901 ( 3.1A)
 0.39A 1m8dB-1m9qA:
56.0		 1m8dB-1m9qA:
61.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M9J_A_CLWA906_1
(ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 5 PRO A 334
VAL A 336
TYR A 357
MET A 358
GLU A 361
 5NI  A 907 ( 4.8A)
5NI  A 907 (-4.4A)
5NI  A 907 (-4.6A)
HEM  A 901 ( 4.4A)
HEM  A 901 ( 3.1A)
 0.48A 1m9jA-1m9qA:
63.3		 1m9jA-1m9qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M9J_B_CLWB907_1
(ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 5 PRO A 334
VAL A 336
TYR A 357
MET A 358
GLU A 361
 5NI  A 907 ( 4.8A)
5NI  A 907 (-4.4A)
5NI  A 907 (-4.6A)
HEM  A 901 ( 4.4A)
HEM  A 901 ( 3.1A)
 0.25A 1m9jB-1m9qA:
63.9		 1m9jB-1m9qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OM5_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 8 TRP A  74
TRP A 445
PHE A 460
GLU A 463
 None
MPD  A 603 (-4.6A)
MPD  A 603 (-4.2A)
None
 0.27A 1om5A-1m9qA:
59.4
1om5B-1m9qA:
59.0		 1om5A-1m9qA:
64.72
1om5B-1m9qA:
64.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P6K_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 6 GLN A 189
TRP A 356
VAL A 418
ALA A 423
SER A 426
 None
HEM  A 901 (-3.6A)
MPD  A 604 (-4.2A)
MPD  A 604 ( 4.0A)
MPD  A 604 (-3.1A)
 0.69A 1p6kA-1m9qA:
59.7		 1p6kA-1m9qA:
64.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P6K_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 6 GLY A 186
GLN A 189
TRP A 356
VAL A 418
ALA A 423
 MPD  A 604 (-3.8A)
None
HEM  A 901 (-3.6A)
MPD  A 604 (-4.2A)
MPD  A 604 ( 4.0A)
 0.15A 1p6kA-1m9qA:
59.7		 1p6kA-1m9qA:
64.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P6K_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 8 ARG A 250
ASN A 267
ASN A 338
TRP A 480
 None
 0.76A 1p6kA-1m9qA:
59.7		 1p6kA-1m9qA:
64.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P6K_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 8 ASN A 267
ASN A 338
ASP A 478
TRP A 480
 None
 0.55A 1p6kA-1m9qA:
59.7		 1p6kA-1m9qA:
64.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P6K_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 8 SER A 246
ARG A 250
ASN A 267
ASN A 338
 None
 0.79A 1p6kA-1m9qA:
59.7		 1p6kA-1m9qA:
64.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P6K_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 5 GLN A 189
TRP A 356
VAL A 418
SER A 426
 None
HEM  A 901 (-3.6A)
MPD  A 604 (-4.2A)
MPD  A 604 (-3.1A)
 0.84A 1p6kB-1m9qA:
59.3		 1p6kB-1m9qA:
64.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P6K_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 5 GLY A 186
GLN A 189
TRP A 356
VAL A 418
 MPD  A 604 (-3.8A)
None
HEM  A 901 (-3.6A)
MPD  A 604 (-4.2A)
 0.21A 1p6kB-1m9qA:
59.3		 1p6kB-1m9qA:
64.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P6K_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 8 ARG A 250
ASN A 267
ASN A 338
TRP A 480
 None
 0.80A 1p6kB-1m9qA:
59.3		 1p6kB-1m9qA:
64.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P6K_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 8 ASN A 267
ASN A 338
ASP A 478
TRP A 480
 None
 0.53A 1p6kB-1m9qA:
59.3		 1p6kB-1m9qA:
64.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P6K_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 8 SER A 246
ARG A 250
ASN A 267
ASN A 338
 None
 0.88A 1p6kB-1m9qA:
59.3		 1p6kB-1m9qA:
64.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_A_RBFA100_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 11 SER A 409
LEU A 407
ILE A 452
ILE A 402
VAL A 400
 None
 0.86A 1pkvA-1m9qA:
undetectable
1pkvB-1m9qA:
undetectable		 1pkvA-1m9qA:
15.69
1pkvB-1m9qA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_B_RBFB101_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 11 ILE A 402
VAL A 400
SER A 409
LEU A 407
ILE A 452
 None
 0.89A 1pkvA-1m9qA:
undetectable
1pkvB-1m9qA:
undetectable		 1pkvA-1m9qA:
15.69
1pkvB-1m9qA:
15.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RS6_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 4 GLN A 189
TRP A 356
VAL A 418
SER A 426
 None
HEM  A 901 (-3.6A)
MPD  A 604 (-4.2A)
MPD  A 604 (-3.1A)
 0.73A 1rs6A-1m9qA:
59.7		 1rs6A-1m9qA:
64.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RS6_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 8 ARG A 250
ASN A 267
ASN A 338
ASP A 478
TRP A 480
 None
 0.65A 1rs6A-1m9qA:
59.7		 1rs6A-1m9qA:
64.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RS6_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 8 SER A 246
ARG A 250
ASN A 267
ASN A 338
 None
 0.70A 1rs6A-1m9qA:
59.7		 1rs6A-1m9qA:
64.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RS6_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 5 GLN A 189
TRP A 356
VAL A 418
SER A 426
 None
HEM  A 901 (-3.6A)
MPD  A 604 (-4.2A)
MPD  A 604 (-3.1A)
 0.82A 1rs6B-1m9qA:
59.2		 1rs6B-1m9qA:
64.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RS6_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 5 GLY A 186
GLN A 189
TRP A 356
VAL A 418
 MPD  A 604 (-3.8A)
None
HEM  A 901 (-3.6A)
MPD  A 604 (-4.2A)
 0.22A 1rs6B-1m9qA:
59.2		 1rs6B-1m9qA:
64.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RS6_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 8 TRP A  74
TRP A 445
PHE A 460
GLU A 463
 None
MPD  A 603 (-4.6A)
MPD  A 603 (-4.2A)
None
 0.14A 1rs6A-1m9qA:
59.7
1rs6B-1m9qA:
59.2		 1rs6A-1m9qA:
64.72
1rs6B-1m9qA:
64.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RS6_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 8 ARG A 250
ASN A 267
ASN A 338
ASP A 478
TRP A 480
 None
 0.70A 1rs6B-1m9qA:
59.2		 1rs6B-1m9qA:
64.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RS6_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 8 SER A 246
ARG A 250
ASN A 267
ASN A 338
 None
 0.83A 1rs6B-1m9qA:
59.2		 1rs6B-1m9qA:
64.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RS7_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 5 GLY A 186
ILE A 188
TRP A 356
VAL A 418
SER A 426
 MPD  A 604 (-3.8A)
None
HEM  A 901 (-3.6A)
MPD  A 604 (-4.2A)
MPD  A 604 (-3.1A)
 0.65A 1rs7A-1m9qA:
59.7		 1rs7A-1m9qA:
64.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RS7_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 6 GLY A 186
ILE A 188
GLN A 189
TRP A 356
VAL A 418
 MPD  A 604 (-3.8A)
None
None
HEM  A 901 (-3.6A)
MPD  A 604 (-4.2A)
 0.25A 1rs7B-1m9qA:
59.3		 1rs7B-1m9qA:
64.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RS7_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 6 ILE A 188
GLN A 189
TRP A 356
VAL A 418
SER A 426
 None
None
HEM  A 901 (-3.6A)
MPD  A 604 (-4.2A)
MPD  A 604 (-3.1A)
 0.81A 1rs7B-1m9qA:
59.3		 1rs7B-1m9qA:
64.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RS7_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 8 ARG A 250
ASN A 267
ASN A 338
ASP A 478
TRP A 480
 None
 0.79A 1rs7B-1m9qA:
59.3		 1rs7B-1m9qA:
64.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RS7_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 8 SER A 246
ARG A 250
ASN A 267
ASN A 338
 None
 0.90A 1rs7B-1m9qA:
59.3		 1rs7B-1m9qA:
64.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_A_TRPA81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.32A 1utdA-1m9qA:
undetectable
1utdB-1m9qA:
undetectable		 1utdA-1m9qA:
9.88
1utdB-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_B_TRPB81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 8 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.35A 1utdB-1m9qA:
undetectable
1utdC-1m9qA:
undetectable		 1utdB-1m9qA:
9.88
1utdC-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_C_TRPC81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.34A 1utdC-1m9qA:
undetectable
1utdD-1m9qA:
undetectable		 1utdC-1m9qA:
9.88
1utdD-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_D_TRPD81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.33A 1utdD-1m9qA:
undetectable
1utdE-1m9qA:
undetectable		 1utdD-1m9qA:
9.88
1utdE-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_F_TRPF81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 8 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.34A 1utdF-1m9qA:
undetectable
1utdG-1m9qA:
undetectable		 1utdF-1m9qA:
9.88
1utdG-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_G_TRPG81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.33A 1utdG-1m9qA:
0.0
1utdH-1m9qA:
0.0		 1utdG-1m9qA:
9.88
1utdH-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_J_TRPJ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 8 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.33A 1utdJ-1m9qA:
undetectable
1utdK-1m9qA:
undetectable		 1utdJ-1m9qA:
9.88
1utdK-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_K_TRPK81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.34A 1utdA-1m9qA:
undetectable
1utdK-1m9qA:
undetectable		 1utdA-1m9qA:
9.88
1utdK-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_M_TRPM81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 11 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 1utdM-1m9qA:
0.0
1utdN-1m9qA:
0.0		 1utdM-1m9qA:
9.88
1utdN-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.33A 1utdN-1m9qA:
undetectable
1utdO-1m9qA:
0.0		 1utdN-1m9qA:
9.88
1utdO-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_Q_TRPQ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.33A 1utdQ-1m9qA:
undetectable
1utdR-1m9qA:
0.0		 1utdQ-1m9qA:
9.88
1utdR-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 1utdR-1m9qA:
0.0
1utdS-1m9qA:
undetectable		 1utdR-1m9qA:
9.88
1utdS-1m9qA:
9.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZQ_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 4 GLY A 186
TRP A 356
VAL A 418
SER A 426
 MPD  A 604 (-3.8A)
HEM  A 901 (-3.6A)
MPD  A 604 (-4.2A)
MPD  A 604 (-3.1A)
 0.11A 1zzqA-1m9qA:
59.6		 1zzqA-1m9qA:
65.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZQ_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 8 ARG A 250
ASN A 267
ASN A 338
ASP A 478
TRP A 480
 None
 0.64A 1zzqA-1m9qA:
59.6		 1zzqA-1m9qA:
65.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZQ_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 8 SER A 246
ARG A 250
ASN A 267
ASN A 338
 None
 0.73A 1zzqA-1m9qA:
59.6		 1zzqA-1m9qA:
65.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZQ_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 5 GLY A 186
GLN A 189
TRP A 356
VAL A 418
SER A 426
 MPD  A 604 (-3.8A)
None
HEM  A 901 (-3.6A)
MPD  A 604 (-4.2A)
MPD  A 604 (-3.1A)
 0.24A 1zzqB-1m9qA:
59.2		 1zzqB-1m9qA:
65.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZQ_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 8 ARG A 250
ASN A 267
ASN A 338
ASP A 478
TRP A 480
 None
 0.70A 1zzqB-1m9qA:
59.2		 1zzqB-1m9qA:
65.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZQ_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 8 SER A 246
ARG A 250
ASN A 267
ASN A 338
 None
 0.86A 1zzqB-1m9qA:
59.2		 1zzqB-1m9qA:
65.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZU_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 5 GLY A 186
GLN A 189
TRP A 356
VAL A 418
SER A 426
 MPD  A 604 (-3.8A)
None
HEM  A 901 (-3.6A)
MPD  A 604 (-4.2A)
MPD  A 604 (-3.1A)
 0.23A 1zzuA-1m9qA:
59.3		 1zzuA-1m9qA:
65.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZU_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 8 ARG A 250
ASN A 267
ASN A 338
ASP A 478
TRP A 480
 None
 0.57A 1zzuA-1m9qA:
59.3		 1zzuA-1m9qA:
65.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZU_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 8 SER A 246
ARG A 250
ASN A 267
ASN A 338
 None
 0.67A 1zzuA-1m9qA:
59.3		 1zzuA-1m9qA:
65.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZU_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 5 GLN A 189
TRP A 356
VAL A 418
SER A 426
 None
HEM  A 901 (-3.6A)
MPD  A 604 (-4.2A)
MPD  A 604 (-3.1A)
 0.82A 1zzuB-1m9qA:
58.7		 1zzuB-1m9qA:
65.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZU_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 5 GLY A 186
GLN A 189
TRP A 356
VAL A 418
 MPD  A 604 (-3.8A)
None
HEM  A 901 (-3.6A)
MPD  A 604 (-4.2A)
 0.18A 1zzuB-1m9qA:
58.7		 1zzuB-1m9qA:
65.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZU_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 8 ARG A 250
ASN A 267
ASN A 338
TRP A 480
 None
 0.80A 1zzuB-1m9qA:
58.7		 1zzuB-1m9qA:
65.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZU_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 8 ASN A 267
ASN A 338
ASP A 478
TRP A 480
 None
 0.49A 1zzuB-1m9qA:
58.7		 1zzuB-1m9qA:
65.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZU_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 8 SER A 246
ARG A 250
ASN A 267
ASN A 338
 None
 0.91A 1zzuB-1m9qA:
58.7		 1zzuB-1m9qA:
65.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B17_A_DIFA701_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 LEU A 170
ALA A 351
ILE A 228
CYH A 201
ASP A 200
 None
 1.14A 2b17A-1m9qA:
undetectable		 2b17A-1m9qA:
14.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2G6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 8 TRP A  74
TRP A 445
PHE A 460
GLU A 463
 None
MPD  A 603 (-4.6A)
MPD  A 603 (-4.2A)
None
 0.16A 2g6hA-1m9qA:
59.6
2g6hB-1m9qA:
59.2		 2g6hA-1m9qA:
65.02
2g6hB-1m9qA:
65.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PH9_A_GNTA301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 7 TYR A 251
TYR A 357
TYR A 373
ILE A 375
 None
5NI  A 907 (-4.6A)
None
None
 1.34A 2ph9A-1m9qA:
0.0
2ph9B-1m9qA:
0.0		 2ph9A-1m9qA:
21.82
2ph9B-1m9qA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA803_0
(FERROCHELATASE)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 5 LEU A 305
PRO A 306
LEU A 309
ILE A 215
 None
 0.82A 2qd4A-1m9qA:
undetectable		 2qd4A-1m9qA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN1_B_FK5B501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 TYR A 251
PHE A 286
ILE A 362
TRP A 330
TYR A 410
 None
 1.50A 2vn1B-1m9qA:
undetectable		 2vn1B-1m9qA:
15.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3B3P_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 8 TRP A  74
TRP A 445
PHE A 460
GLU A 463
 None
MPD  A 603 (-4.6A)
MPD  A 603 (-4.2A)
None
 0.20A 3b3pA-1m9qA:
59.1
3b3pB-1m9qA:
58.9		 3b3pA-1m9qA:
64.72
3b3pB-1m9qA:
64.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_2
(PHOSPHOLIPASE A2)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 7 VAL A 268
ILE A 275
GLN A 276
GLY A 278
 None
 0.84A 3bjwB-1m9qA:
undetectable		 3bjwB-1m9qA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BSZ_F_RTLF178_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 11 LEU A 165
ALA A 174
PHE A 473
ALA A 177
PHE A 348
 None
None
HEM  A 901 (-4.4A)
None
None
 1.42A 3bszF-1m9qA:
undetectable		 3bszF-1m9qA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_A_DIFA1_1
(TRANSTHYRETIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 6 LEU A 328
ALA A 324
LEU A 315
SER A 409
 None
 1.06A 3cfqA-1m9qA:
undetectable		 3cfqA-1m9qA:
15.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DQT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 7 SER A 102
VAL A 104
ARG A 365
TRP A 447
 None
MPD  A 605 (-4.7A)
MPD  A 605 ( 4.7A)
MPD  A 605 ( 4.0A)
 0.32A 3dqtA-1m9qA:
15.6
3dqtB-1m9qA:
62.1		 3dqtA-1m9qA:
95.17
3dqtB-1m9qA:
95.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3E7G_D_H4BD3902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 8 TRP A  74
TRP A 445
PHE A 460
GLU A 463
 None
MPD  A 603 (-4.6A)
MPD  A 603 (-4.2A)
None
 0.15A 3e7gC-1m9qA:
55.2
3e7gD-1m9qA:
14.4		 3e7gC-1m9qA:
60.10
3e7gD-1m9qA:
60.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N5T_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 7 SER A 102
VAL A 104
ARG A 365
TRP A 447
 None
MPD  A 605 (-4.7A)
MPD  A 605 ( 4.7A)
MPD  A 605 ( 4.0A)
 0.41A 3n5tA-1m9qA:
62.3
3n5tB-1m9qA:
62.2		 3n5tA-1m9qA:
95.17
3n5tB-1m9qA:
95.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N62_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		6 / 8 SER A 246
ARG A 250
ASN A 267
ASN A 338
ASP A 478
TRP A 480
 None
 0.65A 3n62A-1m9qA:
15.0		 3n62A-1m9qA:
64.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N62_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		3 / 3 GLY A 186
TRP A 356
VAL A 418
 MPD  A 604 (-3.8A)
HEM  A 901 (-3.6A)
MPD  A 604 (-4.2A)
 0.09A 3n62B-1m9qA:
59.2		 3n62B-1m9qA:
64.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N62_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 8 ARG A 250
ASN A 267
ASN A 338
ASP A 478
TRP A 480
 None
 0.66A 3n62B-1m9qA:
59.2		 3n62B-1m9qA:
64.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N62_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 8 SER A 246
ARG A 250
ASN A 267
ASN A 338
 None
 0.74A 3n62B-1m9qA:
59.2		 3n62B-1m9qA:
64.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N65_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		3 / 3 GLY A 186
TRP A 356
VAL A 418
 MPD  A 604 (-3.8A)
HEM  A 901 (-3.6A)
MPD  A 604 (-4.2A)
 0.10A 3n65B-1m9qA:
59.2		 3n65B-1m9qA:
64.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N65_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		6 / 9 SER A 246
ARG A 250
ASN A 267
ASN A 338
ASP A 478
TRP A 480
 None
 0.66A 3n65B-1m9qA:
59.2		 3n65B-1m9qA:
64.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N65_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 SER A 246
ARG A 250
ASN A 267
ASN A 338
TYR A 475
 None
None
None
None
HEM  A 901 (-4.2A)
 1.16A 3n65B-1m9qA:
59.2		 3n65B-1m9qA:
64.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N66_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		3 / 3 GLY A 186
TRP A 356
VAL A 418
 MPD  A 604 (-3.8A)
HEM  A 901 (-3.6A)
MPD  A 604 (-4.2A)
 0.10A 3n66B-1m9qA:
30.8		 3n66B-1m9qA:
64.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N66_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		6 / 8 SER A 246
ARG A 250
ASN A 267
ASN A 338
ASP A 478
TRP A 480
 None
 0.56A 3n66B-1m9qA:
30.8		 3n66B-1m9qA:
64.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N6D_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 6 VAL A 104
ARG A 365
TRP A 447
PRO A 451
 MPD  A 605 (-4.7A)
MPD  A 605 ( 4.7A)
MPD  A 605 ( 4.0A)
None
 0.45A 3n6dA-1m9qA:
34.9
3n6dB-1m9qA:
60.3		 3n6dA-1m9qA:
94.93
3n6dB-1m9qA:
94.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NLQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 8 TRP A  74
TRP A 445
PHE A 460
GLU A 463
 None
MPD  A 603 (-4.6A)
MPD  A 603 (-4.2A)
None
 0.23A 3nlqA-1m9qA:
59.2
3nlqB-1m9qA:
58.7		 3nlqA-1m9qA:
65.19
3nlqB-1m9qA:
65.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NLR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 8 SER A 102
VAL A 104
ARG A 365
TRP A 447
 None
MPD  A 605 (-4.7A)
MPD  A 605 ( 4.7A)
MPD  A 605 ( 4.0A)
 0.22A 3nlrA-1m9qA:
59.6
3nlrB-1m9qA:
30.7		 3nlrA-1m9qA:
65.19
3nlrB-1m9qA:
65.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VKX_A_T3A301_1
(PROLIFERATING CELL
NUCLEAR ANTIGEN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 6 LEU A 273
PRO A 479
GLN A 294
PRO A 300
 None
 1.23A 3vkxA-1m9qA:
undetectable		 3vkxA-1m9qA:
21.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CWX_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 7 TRP A  74
TRP A 445
PHE A 460
GLU A 463
 None
MPD  A 603 (-4.6A)
MPD  A 603 (-4.2A)
None
 0.19A 4cwxA-1m9qA:
62.6
4cwxB-1m9qA:
16.1		 4cwxA-1m9qA:
95.17
4cwxB-1m9qA:
95.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CWY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 7 TRP A  74
TRP A 445
PHE A 460
GLU A 463
 None
MPD  A 603 (-4.6A)
MPD  A 603 (-4.2A)
None
 0.19A 4cwyA-1m9qA:
62.6
4cwyB-1m9qA:
16.0		 4cwyA-1m9qA:
95.17
4cwyB-1m9qA:
95.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CWY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 7 TRP A  74
TRP A 445
PHE A 460
GLU A 463
 None
MPD  A 603 (-4.6A)
MPD  A 603 (-4.2A)
None
 0.19A 4cwyA-1m9qA:
62.6
4cwyB-1m9qA:
16.0		 4cwyA-1m9qA:
95.17
4cwyB-1m9qA:
95.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CX7_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 8 TRP A 445
PHE A 460
HIS A 461
GLU A 463
 MPD  A 603 (-4.6A)
MPD  A 603 (-4.2A)
None
None
 0.21A 4cx7A-1m9qA:
55.1
4cx7B-1m9qA:
55.0		 4cx7A-1m9qA:
59.43
4cx7B-1m9qA:
59.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4D33_A_ACTA860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 5 GLY A 186
ILE A 188
TRP A 356
VAL A 418
SER A 426
 MPD  A 604 (-3.8A)
None
HEM  A 901 (-3.6A)
MPD  A 604 (-4.2A)
MPD  A 604 (-3.1A)
 0.27A 4d33A-1m9qA:
61.1		 4d33A-1m9qA:
95.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4D33_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		8 / 8 SER A 246
ARG A 250
ASN A 267
GLU A 269
ILE A 270
ASN A 338
ASP A 478
TRP A 480
 None
 0.60A 4d33A-1m9qA:
61.1		 4d33A-1m9qA:
95.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4D33_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 5 GLY A 186
ILE A 188
TRP A 356
VAL A 418
SER A 426
 MPD  A 604 (-3.8A)
None
HEM  A 901 (-3.6A)
MPD  A 604 (-4.2A)
MPD  A 604 (-3.1A)
 0.27A 4d33B-1m9qA:
61.2		 4d33B-1m9qA:
95.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4D33_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		7 / 7 SER A 246
ARG A 250
ASN A 267
GLU A 269
ILE A 270
ASN A 338
ASP A 478
 None
 0.57A 4d33B-1m9qA:
61.2		 4d33B-1m9qA:
95.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4D39_A_ACTA860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 4 GLY A 186
TRP A 356
VAL A 418
SER A 426
 MPD  A 604 (-3.8A)
HEM  A 901 (-3.6A)
MPD  A 604 (-4.2A)
MPD  A 604 (-3.1A)
 0.20A 4d39A-1m9qA:
62.4		 4d39A-1m9qA:
95.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4D39_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		8 / 8 SER A 246
ARG A 250
ASN A 267
GLU A 269
ILE A 270
ASN A 338
ASP A 478
TRP A 480
 None
 0.48A 4d39A-1m9qA:
62.4		 4d39A-1m9qA:
95.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4D39_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		6 / 6 GLY A 186
ILE A 188
GLN A 189
TRP A 356
VAL A 418
SER A 426
 MPD  A 604 (-3.8A)
None
None
HEM  A 901 (-3.6A)
MPD  A 604 (-4.2A)
MPD  A 604 (-3.1A)
 0.26A 4d39B-1m9qA:
62.4		 4d39B-1m9qA:
95.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4D39_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		7 / 7 SER A 246
ARG A 250
ASN A 267
GLU A 269
ILE A 270
ASN A 338
ASP A 478
 None
 0.51A 4d39B-1m9qA:
62.4		 4d39B-1m9qA:
95.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_A_SUZA201_1
(TRANSTHYRETIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 7 LEU A 326
ALA A 324
LEU A 328
SER A 409
 None
 1.04A 4ikjA-1m9qA:
undetectable
4ikjB-1m9qA:
undetectable		 4ikjA-1m9qA:
15.48
4ikjB-1m9qA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_B_SUZB201_1
(TRANSTHYRETIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 7 SER A 409
LEU A 326
ALA A 324
LEU A 328
 None
 1.04A 4ikkA-1m9qA:
undetectable
4ikkB-1m9qA:
undetectable		 4ikkA-1m9qA:
15.48
4ikkB-1m9qA:
15.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K5J_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 7 SER A 102
VAL A 104
ARG A 365
TRP A 447
 None
MPD  A 605 (-4.7A)
MPD  A 605 ( 4.7A)
MPD  A 605 ( 4.0A)
 0.35A 4k5jA-1m9qA:
62.6
4k5jB-1m9qA:
62.7		 4k5jA-1m9qA:
95.17
4k5jB-1m9qA:
95.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KCN_A_ACTA803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 6 GLY A 186
ILE A 188
GLN A 189
TRP A 356
VAL A 418
 MPD  A 604 (-3.8A)
None
None
HEM  A 901 (-3.6A)
MPD  A 604 (-4.2A)
 0.13A 4kcnA-1m9qA:
59.8		 4kcnA-1m9qA:
64.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KCN_A_ACTA803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 6 ILE A 188
GLN A 189
TRP A 356
VAL A 418
SER A 426
 None
None
HEM  A 901 (-3.6A)
MPD  A 604 (-4.2A)
MPD  A 604 (-3.1A)
 0.64A 4kcnA-1m9qA:
59.8		 4kcnA-1m9qA:
64.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KCN_A_MTLA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 6 ARG A 250
ARG A 365
ASP A 369
ARG A 372
 None
MPD  A 605 ( 4.7A)
None
None
 0.44A 4kcnA-1m9qA:
59.8		 4kcnA-1m9qA:
64.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KCN_B_ACTB804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 4 GLY A 186
GLN A 189
TRP A 356
VAL A 418
 MPD  A 604 (-3.8A)
None
HEM  A 901 (-3.6A)
MPD  A 604 (-4.2A)
 0.19A 4kcnB-1m9qA:
59.1		 4kcnB-1m9qA:
64.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KCN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 6 ARG A 250
ARG A 365
ASP A 369
ARG A 372
 None
MPD  A 605 ( 4.7A)
None
None
 0.42A 4kcnB-1m9qA:
59.1		 4kcnB-1m9qA:
64.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KCN_B_MTLB806_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 7 SER A 246
ASN A 267
ASN A 338
ASP A 478
TRP A 480
 None
 0.46A 4kcnB-1m9qA:
59.1		 4kcnB-1m9qA:
64.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_2
(ANDROGEN RECEPTOR)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 8 LEU A 292
ASN A 245
LEU A 304
ILE A 215
 None
 1.07A 4ok1A-1m9qA:
undetectable		 4ok1A-1m9qA:
19.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UCH_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 8 TRP A  74
TRP A 445
PHE A 460
GLU A 463
 None
MPD  A 603 (-4.6A)
MPD  A 603 (-4.2A)
None
 0.19A 4uchA-1m9qA:
58.8
4uchB-1m9qA:
59.3		 4uchA-1m9qA:
65.64
4uchB-1m9qA:
65.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V3W_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 7 TRP A  74
TRP A 445
PHE A 460
GLU A 463
 None
MPD  A 603 (-4.6A)
MPD  A 603 (-4.2A)
None
 0.17A 4v3wA-1m9qA:
59.3
4v3wB-1m9qA:
58.9		 4v3wA-1m9qA:
64.72
4v3wB-1m9qA:
64.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AD9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 7 TRP A 445
PHE A 460
HIS A 461
GLU A 463
 MPD  A 603 (-4.6A)
MPD  A 603 (-4.2A)
None
None
 0.27A 5ad9A-1m9qA:
59.2
5ad9B-1m9qA:
30.4		 5ad9A-1m9qA:
64.72
5ad9B-1m9qA:
64.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ADL_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 7 SER A 102
VAL A 104
ARG A 365
TRP A 447
 None
MPD  A 605 (-4.7A)
MPD  A 605 ( 4.7A)
MPD  A 605 ( 4.0A)
 0.32A 5adlA-1m9qA:
62.0
5adlB-1m9qA:
14.2		 5adlA-1m9qA:
95.17
5adlB-1m9qA:
95.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.35A 5eeuA-1m9qA:
undetectable
5eeuB-1m9qA:
undetectable		 5eeuA-1m9qA:
9.88
5eeuB-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.30A 5eeuB-1m9qA:
undetectable
5eeuC-1m9qA:
undetectable		 5eeuB-1m9qA:
9.88
5eeuC-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.33A 5eeuC-1m9qA:
undetectable
5eeuD-1m9qA:
undetectable		 5eeuC-1m9qA:
9.88
5eeuD-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.34A 5eeuD-1m9qA:
0.0
5eeuE-1m9qA:
undetectable		 5eeuD-1m9qA:
9.88
5eeuE-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.31A 5eeuE-1m9qA:
undetectable
5eeuF-1m9qA:
undetectable		 5eeuE-1m9qA:
9.88
5eeuF-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.34A 5eeuG-1m9qA:
undetectable
5eeuH-1m9qA:
undetectable		 5eeuG-1m9qA:
9.88
5eeuH-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.32A 5eeuH-1m9qA:
0.0
5eeuI-1m9qA:
undetectable		 5eeuH-1m9qA:
9.88
5eeuI-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.31A 5eeuJ-1m9qA:
0.0
5eeuK-1m9qA:
0.0		 5eeuJ-1m9qA:
9.88
5eeuK-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.37A 5eeuA-1m9qA:
undetectable
5eeuK-1m9qA:
0.0		 5eeuA-1m9qA:
9.88
5eeuK-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 5eeuN-1m9qA:
0.0
5eeuO-1m9qA:
0.0		 5eeuN-1m9qA:
9.88
5eeuO-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.40A 5eeuP-1m9qA:
0.0
5eeuQ-1m9qA:
0.0		 5eeuP-1m9qA:
9.88
5eeuQ-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 5eeuR-1m9qA:
0.0
5eeuS-1m9qA:
0.0		 5eeuR-1m9qA:
9.88
5eeuS-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.33A 5eeuS-1m9qA:
0.0
5eeuT-1m9qA:
0.0		 5eeuS-1m9qA:
9.88
5eeuT-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 5eeuT-1m9qA:
0.0
5eeuU-1m9qA:
0.0		 5eeuT-1m9qA:
9.88
5eeuU-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.35A 5eeuU-1m9qA:
0.0
5eeuV-1m9qA:
0.0		 5eeuU-1m9qA:
9.88
5eeuV-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.31A 5eevB-1m9qA:
undetectable
5eevC-1m9qA:
undetectable		 5eevB-1m9qA:
9.88
5eevC-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.33A 5eevC-1m9qA:
undetectable
5eevD-1m9qA:
0.0		 5eevC-1m9qA:
9.88
5eevD-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.34A 5eevD-1m9qA:
0.0
5eevE-1m9qA:
undetectable		 5eevD-1m9qA:
9.88
5eevE-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.31A 5eevE-1m9qA:
undetectable
5eevF-1m9qA:
undetectable		 5eevE-1m9qA:
9.88
5eevF-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.34A 5eevG-1m9qA:
undetectable
5eevH-1m9qA:
undetectable		 5eevG-1m9qA:
9.88
5eevH-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.32A 5eevH-1m9qA:
0.0
5eevI-1m9qA:
undetectable		 5eevH-1m9qA:
9.88
5eevI-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.31A 5eevJ-1m9qA:
0.0
5eevK-1m9qA:
0.0		 5eevJ-1m9qA:
9.88
5eevK-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.37A 5eevA-1m9qA:
undetectable
5eevK-1m9qA:
0.0		 5eevA-1m9qA:
9.88
5eevK-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 5eevN-1m9qA:
0.0
5eevO-1m9qA:
0.0		 5eevN-1m9qA:
9.88
5eevO-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.40A 5eevP-1m9qA:
0.0
5eevQ-1m9qA:
0.0		 5eevP-1m9qA:
9.88
5eevQ-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 5eevR-1m9qA:
0.0
5eevS-1m9qA:
0.0		 5eevR-1m9qA:
9.88
5eevS-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.33A 5eevS-1m9qA:
0.0
5eevT-1m9qA:
0.0		 5eevS-1m9qA:
9.88
5eevT-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 5eevT-1m9qA:
0.0
5eevU-1m9qA:
0.0		 5eevT-1m9qA:
9.88
5eevU-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.35A 5eevU-1m9qA:
0.0
5eevV-1m9qA:
0.0		 5eevU-1m9qA:
9.88
5eevV-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.31A 5eewB-1m9qA:
undetectable
5eewC-1m9qA:
undetectable		 5eewB-1m9qA:
9.88
5eewC-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.33A 5eewC-1m9qA:
undetectable
5eewD-1m9qA:
undetectable		 5eewC-1m9qA:
9.88
5eewD-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.34A 5eewD-1m9qA:
undetectable
5eewE-1m9qA:
undetectable		 5eewD-1m9qA:
9.88
5eewE-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.31A 5eewE-1m9qA:
undetectable
5eewF-1m9qA:
0.0		 5eewE-1m9qA:
9.88
5eewF-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.34A 5eewG-1m9qA:
0.0
5eewH-1m9qA:
undetectable		 5eewG-1m9qA:
9.88
5eewH-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.32A 5eewH-1m9qA:
0.0
5eewI-1m9qA:
undetectable		 5eewH-1m9qA:
9.88
5eewI-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.31A 5eewJ-1m9qA:
undetectable
5eewK-1m9qA:
0.0		 5eewJ-1m9qA:
9.88
5eewK-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.37A 5eewA-1m9qA:
undetectable
5eewK-1m9qA:
0.0		 5eewA-1m9qA:
9.88
5eewK-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 5eewN-1m9qA:
undetectable
5eewO-1m9qA:
0.0		 5eewN-1m9qA:
9.88
5eewO-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.40A 5eewP-1m9qA:
undetectable
5eewQ-1m9qA:
0.0		 5eewP-1m9qA:
9.88
5eewQ-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 5eewR-1m9qA:
0.0
5eewS-1m9qA:
0.0		 5eewR-1m9qA:
9.88
5eewS-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.33A 5eewS-1m9qA:
0.0
5eewT-1m9qA:
0.0		 5eewS-1m9qA:
9.88
5eewT-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 5eewT-1m9qA:
0.0
5eewU-1m9qA:
undetectable		 5eewT-1m9qA:
9.88
5eewU-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.35A 5eewU-1m9qA:
0.0
5eewV-1m9qA:
0.0		 5eewU-1m9qA:
9.88
5eewV-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.30A 5eexB-1m9qA:
undetectable
5eexC-1m9qA:
undetectable		 5eexB-1m9qA:
9.88
5eexC-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.33A 5eexC-1m9qA:
undetectable
5eexD-1m9qA:
undetectable		 5eexC-1m9qA:
9.88
5eexD-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.34A 5eexD-1m9qA:
undetectable
5eexE-1m9qA:
undetectable		 5eexD-1m9qA:
9.88
5eexE-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.31A 5eexE-1m9qA:
undetectable
5eexF-1m9qA:
0.0		 5eexE-1m9qA:
9.88
5eexF-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.34A 5eexG-1m9qA:
undetectable
5eexH-1m9qA:
undetectable		 5eexG-1m9qA:
9.88
5eexH-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.32A 5eexH-1m9qA:
0.0
5eexI-1m9qA:
undetectable		 5eexH-1m9qA:
9.88
5eexI-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 11 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.33A 5eexI-1m9qA:
undetectable
5eexJ-1m9qA:
0.0		 5eexI-1m9qA:
9.88
5eexJ-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.32A 5eexJ-1m9qA:
0.0
5eexK-1m9qA:
0.0		 5eexJ-1m9qA:
9.88
5eexK-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.37A 5eexA-1m9qA:
undetectable
5eexK-1m9qA:
0.0		 5eexA-1m9qA:
9.88
5eexK-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 5eexN-1m9qA:
0.0
5eexO-1m9qA:
0.0		 5eexN-1m9qA:
9.88
5eexO-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.40A 5eexP-1m9qA:
0.0
5eexQ-1m9qA:
0.0		 5eexP-1m9qA:
9.88
5eexQ-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.38A 5eexQ-1m9qA:
0.0
5eexR-1m9qA:
0.0		 5eexQ-1m9qA:
9.88
5eexR-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 5eexR-1m9qA:
0.0
5eexS-1m9qA:
0.0		 5eexR-1m9qA:
9.88
5eexS-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.33A 5eexS-1m9qA:
undetectable
5eexT-1m9qA:
0.0		 5eexS-1m9qA:
9.88
5eexT-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 5eexT-1m9qA:
0.0
5eexU-1m9qA:
0.0		 5eexT-1m9qA:
9.88
5eexU-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.35A 5eexU-1m9qA:
0.0
5eexV-1m9qA:
0.0		 5eexU-1m9qA:
9.88
5eexV-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.31A 5eeyB-1m9qA:
undetectable
5eeyC-1m9qA:
undetectable		 5eeyB-1m9qA:
9.88
5eeyC-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.33A 5eeyC-1m9qA:
undetectable
5eeyD-1m9qA:
undetectable		 5eeyC-1m9qA:
9.88
5eeyD-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.34A 5eeyD-1m9qA:
undetectable
5eeyE-1m9qA:
undetectable		 5eeyD-1m9qA:
9.88
5eeyE-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.31A 5eeyE-1m9qA:
undetectable
5eeyF-1m9qA:
0.0		 5eeyE-1m9qA:
9.88
5eeyF-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.34A 5eeyG-1m9qA:
undetectable
5eeyH-1m9qA:
undetectable		 5eeyG-1m9qA:
9.88
5eeyH-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.32A 5eeyH-1m9qA:
undetectable
5eeyI-1m9qA:
undetectable		 5eeyH-1m9qA:
9.88
5eeyI-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 11 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.33A 5eeyI-1m9qA:
undetectable
5eeyJ-1m9qA:
0.0		 5eeyI-1m9qA:
9.88
5eeyJ-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.32A 5eeyJ-1m9qA:
0.0
5eeyK-1m9qA:
0.0		 5eeyJ-1m9qA:
9.88
5eeyK-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.37A 5eeyA-1m9qA:
undetectable
5eeyK-1m9qA:
0.0		 5eeyA-1m9qA:
9.88
5eeyK-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 5eeyN-1m9qA:
0.0
5eeyO-1m9qA:
0.0		 5eeyN-1m9qA:
9.88
5eeyO-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.40A 5eeyP-1m9qA:
0.0
5eeyQ-1m9qA:
undetectable		 5eeyP-1m9qA:
9.88
5eeyQ-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.38A 5eeyQ-1m9qA:
0.0
5eeyR-1m9qA:
0.0		 5eeyQ-1m9qA:
9.88
5eeyR-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 5eeyR-1m9qA:
0.0
5eeyS-1m9qA:
0.0		 5eeyR-1m9qA:
9.88
5eeyS-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.33A 5eeyS-1m9qA:
0.0
5eeyT-1m9qA:
0.0		 5eeyS-1m9qA:
9.88
5eeyT-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 5eeyT-1m9qA:
0.0
5eeyU-1m9qA:
0.0		 5eeyT-1m9qA:
9.88
5eeyU-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.35A 5eeyU-1m9qA:
0.0
5eeyV-1m9qA:
0.0		 5eeyU-1m9qA:
9.88
5eeyV-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.31A 5eezB-1m9qA:
undetectable
5eezC-1m9qA:
undetectable		 5eezB-1m9qA:
9.88
5eezC-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.33A 5eezC-1m9qA:
undetectable
5eezD-1m9qA:
0.0		 5eezC-1m9qA:
9.88
5eezD-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.34A 5eezD-1m9qA:
0.0
5eezE-1m9qA:
undetectable		 5eezD-1m9qA:
9.88
5eezE-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.31A 5eezE-1m9qA:
undetectable
5eezF-1m9qA:
undetectable		 5eezE-1m9qA:
9.88
5eezF-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.34A 5eezG-1m9qA:
undetectable
5eezH-1m9qA:
undetectable		 5eezG-1m9qA:
9.88
5eezH-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.32A 5eezH-1m9qA:
undetectable
5eezI-1m9qA:
undetectable		 5eezH-1m9qA:
9.88
5eezI-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 11 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.33A 5eezI-1m9qA:
undetectable
5eezJ-1m9qA:
0.0		 5eezI-1m9qA:
9.88
5eezJ-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.32A 5eezJ-1m9qA:
0.0
5eezK-1m9qA:
0.0		 5eezJ-1m9qA:
9.88
5eezK-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.37A 5eezA-1m9qA:
0.0
5eezK-1m9qA:
0.0		 5eezA-1m9qA:
9.88
5eezK-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 5eezN-1m9qA:
0.0
5eezO-1m9qA:
0.0		 5eezN-1m9qA:
9.88
5eezO-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.40A 5eezP-1m9qA:
0.0
5eezQ-1m9qA:
0.0		 5eezP-1m9qA:
9.88
5eezQ-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.38A 5eezQ-1m9qA:
0.0
5eezR-1m9qA:
0.0		 5eezQ-1m9qA:
9.88
5eezR-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 5eezR-1m9qA:
0.0
5eezS-1m9qA:
0.0		 5eezR-1m9qA:
9.88
5eezS-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.33A 5eezS-1m9qA:
0.0
5eezT-1m9qA:
0.0		 5eezS-1m9qA:
9.88
5eezT-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 5eezT-1m9qA:
0.0
5eezU-1m9qA:
0.0		 5eezT-1m9qA:
9.88
5eezU-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.35A 5eezU-1m9qA:
0.0
5eezV-1m9qA:
0.0		 5eezU-1m9qA:
9.88
5eezV-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.31A 5ef0B-1m9qA:
undetectable
5ef0C-1m9qA:
undetectable		 5ef0B-1m9qA:
9.88
5ef0C-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.33A 5ef0C-1m9qA:
undetectable
5ef0D-1m9qA:
undetectable		 5ef0C-1m9qA:
9.88
5ef0D-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.34A 5ef0D-1m9qA:
0.0
5ef0E-1m9qA:
undetectable		 5ef0D-1m9qA:
9.88
5ef0E-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.31A 5ef0E-1m9qA:
undetectable
5ef0F-1m9qA:
0.0		 5ef0E-1m9qA:
9.88
5ef0F-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.34A 5ef0G-1m9qA:
0.0
5ef0H-1m9qA:
undetectable		 5ef0G-1m9qA:
9.88
5ef0H-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.32A 5ef0H-1m9qA:
undetectable
5ef0I-1m9qA:
undetectable		 5ef0H-1m9qA:
9.88
5ef0I-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 11 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.33A 5ef0I-1m9qA:
undetectable
5ef0J-1m9qA:
undetectable		 5ef0I-1m9qA:
9.88
5ef0J-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.32A 5ef0J-1m9qA:
undetectable
5ef0K-1m9qA:
0.0		 5ef0J-1m9qA:
9.88
5ef0K-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.37A 5ef0A-1m9qA:
0.0
5ef0K-1m9qA:
0.0		 5ef0A-1m9qA:
9.88
5ef0K-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 5ef0N-1m9qA:
0.0
5ef0O-1m9qA:
0.0		 5ef0N-1m9qA:
9.88
5ef0O-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.40A 5ef0P-1m9qA:
0.0
5ef0Q-1m9qA:
0.0		 5ef0P-1m9qA:
9.88
5ef0Q-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.38A 5ef0Q-1m9qA:
0.0
5ef0R-1m9qA:
0.0		 5ef0Q-1m9qA:
9.88
5ef0R-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 5ef0R-1m9qA:
0.0
5ef0S-1m9qA:
0.0		 5ef0R-1m9qA:
9.88
5ef0S-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.33A 5ef0S-1m9qA:
0.0
5ef0T-1m9qA:
0.0		 5ef0S-1m9qA:
9.88
5ef0T-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 5ef0T-1m9qA:
0.0
5ef0U-1m9qA:
0.0		 5ef0T-1m9qA:
9.88
5ef0U-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.35A 5ef0U-1m9qA:
0.0
5ef0V-1m9qA:
0.0		 5ef0U-1m9qA:
9.88
5ef0V-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.31A 5ef1B-1m9qA:
undetectable
5ef1C-1m9qA:
undetectable		 5ef1B-1m9qA:
9.88
5ef1C-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.33A 5ef1C-1m9qA:
undetectable
5ef1D-1m9qA:
undetectable		 5ef1C-1m9qA:
9.88
5ef1D-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.34A 5ef1D-1m9qA:
undetectable
5ef1E-1m9qA:
undetectable		 5ef1D-1m9qA:
9.88
5ef1E-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.31A 5ef1E-1m9qA:
undetectable
5ef1F-1m9qA:
undetectable		 5ef1E-1m9qA:
9.88
5ef1F-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.34A 5ef1G-1m9qA:
0.0
5ef1H-1m9qA:
0.0		 5ef1G-1m9qA:
9.88
5ef1H-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.32A 5ef1H-1m9qA:
0.0
5ef1I-1m9qA:
undetectable		 5ef1H-1m9qA:
9.88
5ef1I-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 11 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.33A 5ef1I-1m9qA:
undetectable
5ef1J-1m9qA:
undetectable		 5ef1I-1m9qA:
9.88
5ef1J-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.32A 5ef1J-1m9qA:
0.0
5ef1K-1m9qA:
0.0		 5ef1J-1m9qA:
9.88
5ef1K-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.38A 5ef1A-1m9qA:
0.0
5ef1K-1m9qA:
0.0		 5ef1A-1m9qA:
9.88
5ef1K-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 5ef1N-1m9qA:
0.0
5ef1O-1m9qA:
0.0		 5ef1N-1m9qA:
9.88
5ef1O-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.40A 5ef1P-1m9qA:
undetectable
5ef1Q-1m9qA:
0.0		 5ef1P-1m9qA:
9.88
5ef1Q-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.39A 5ef1Q-1m9qA:
0.0
5ef1R-1m9qA:
0.0		 5ef1Q-1m9qA:
9.88
5ef1R-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 5ef1R-1m9qA:
0.0
5ef1S-1m9qA:
0.0		 5ef1R-1m9qA:
9.88
5ef1S-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.33A 5ef1S-1m9qA:
0.0
5ef1T-1m9qA:
0.0		 5ef1S-1m9qA:
9.88
5ef1T-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 5ef1T-1m9qA:
0.0
5ef1U-1m9qA:
0.0		 5ef1T-1m9qA:
9.88
5ef1U-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.35A 5ef1U-1m9qA:
0.0
5ef1V-1m9qA:
0.0		 5ef1U-1m9qA:
9.88
5ef1V-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.31A 5ef2B-1m9qA:
undetectable
5ef2C-1m9qA:
0.0		 5ef2B-1m9qA:
9.88
5ef2C-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.33A 5ef2C-1m9qA:
0.0
5ef2D-1m9qA:
undetectable		 5ef2C-1m9qA:
9.88
5ef2D-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.34A 5ef2D-1m9qA:
undetectable
5ef2E-1m9qA:
0.0		 5ef2D-1m9qA:
9.88
5ef2E-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.31A 5ef2E-1m9qA:
undetectable
5ef2F-1m9qA:
0.0		 5ef2E-1m9qA:
9.88
5ef2F-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.34A 5ef2G-1m9qA:
undetectable
5ef2H-1m9qA:
0.0		 5ef2G-1m9qA:
9.88
5ef2H-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.32A 5ef2H-1m9qA:
0.0
5ef2I-1m9qA:
undetectable		 5ef2H-1m9qA:
9.88
5ef2I-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 11 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.33A 5ef2I-1m9qA:
undetectable
5ef2J-1m9qA:
undetectable		 5ef2I-1m9qA:
9.88
5ef2J-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.32A 5ef2J-1m9qA:
undetectable
5ef2K-1m9qA:
0.0		 5ef2J-1m9qA:
9.88
5ef2K-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.38A 5ef2A-1m9qA:
0.0
5ef2K-1m9qA:
0.0		 5ef2A-1m9qA:
9.88
5ef2K-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 5ef2N-1m9qA:
0.0
5ef2O-1m9qA:
0.0		 5ef2N-1m9qA:
9.88
5ef2O-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.40A 5ef2P-1m9qA:
0.0
5ef2Q-1m9qA:
0.0		 5ef2P-1m9qA:
9.88
5ef2Q-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.38A 5ef2Q-1m9qA:
0.0
5ef2R-1m9qA:
0.0		 5ef2Q-1m9qA:
9.88
5ef2R-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 5ef2R-1m9qA:
0.0
5ef2S-1m9qA:
0.0		 5ef2R-1m9qA:
9.88
5ef2S-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.33A 5ef2S-1m9qA:
0.0
5ef2T-1m9qA:
0.0		 5ef2S-1m9qA:
9.88
5ef2T-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 5ef2T-1m9qA:
0.0
5ef2U-1m9qA:
0.0		 5ef2T-1m9qA:
9.88
5ef2U-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.35A 5ef2U-1m9qA:
0.0
5ef2V-1m9qA:
0.0		 5ef2U-1m9qA:
9.88
5ef2V-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.31A 5ef3B-1m9qA:
undetectable
5ef3C-1m9qA:
0.0		 5ef3B-1m9qA:
9.88
5ef3C-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.33A 5ef3C-1m9qA:
0.0
5ef3D-1m9qA:
0.0		 5ef3C-1m9qA:
9.88
5ef3D-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.34A 5ef3D-1m9qA:
0.0
5ef3E-1m9qA:
undetectable		 5ef3D-1m9qA:
9.88
5ef3E-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.32A 5ef3E-1m9qA:
undetectable
5ef3F-1m9qA:
undetectable		 5ef3E-1m9qA:
9.88
5ef3F-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.34A 5ef3G-1m9qA:
undetectable
5ef3H-1m9qA:
undetectable		 5ef3G-1m9qA:
9.88
5ef3H-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.32A 5ef3H-1m9qA:
0.0
5ef3I-1m9qA:
0.0		 5ef3H-1m9qA:
9.88
5ef3I-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 11 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.33A 5ef3I-1m9qA:
undetectable
5ef3J-1m9qA:
undetectable		 5ef3I-1m9qA:
9.88
5ef3J-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 360
THR A 457
HIS A 421
THR A 424
ILE A 448
 None
 1.32A 5ef3J-1m9qA:
undetectable
5ef3K-1m9qA:
0.0		 5ef3J-1m9qA:
9.88
5ef3K-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.37A 5ef3A-1m9qA:
0.0
5ef3K-1m9qA:
0.0		 5ef3A-1m9qA:
9.88
5ef3K-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 5ef3N-1m9qA:
0.0
5ef3O-1m9qA:
0.0		 5ef3N-1m9qA:
9.88
5ef3O-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.41A 5ef3P-1m9qA:
undetectable
5ef3Q-1m9qA:
0.0		 5ef3P-1m9qA:
9.88
5ef3Q-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 9 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.38A 5ef3Q-1m9qA:
0.0
5ef3R-1m9qA:
0.0		 5ef3Q-1m9qA:
9.88
5ef3R-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 5ef3R-1m9qA:
0.0
5ef3S-1m9qA:
0.0		 5ef3R-1m9qA:
9.88
5ef3S-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.33A 5ef3S-1m9qA:
0.0
5ef3T-1m9qA:
0.0		 5ef3S-1m9qA:
9.88
5ef3T-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 5ef3T-1m9qA:
0.0
5ef3U-1m9qA:
0.0		 5ef3T-1m9qA:
9.88
5ef3U-1m9qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 THR A 457
HIS A 421
THR A 424
ILE A 448
THR A 360
 None
 1.36A 5ef3U-1m9qA:
0.0
5ef3V-1m9qA:
0.0		 5ef3U-1m9qA:
9.88
5ef3V-1m9qA:
9.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FJ3_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 7 SER A 102
VAL A 104
ARG A 365
TRP A 447
 None
MPD  A 605 (-4.7A)
MPD  A 605 ( 4.7A)
MPD  A 605 ( 4.0A)
 0.30A 5fj3A-1m9qA:
62.7
5fj3B-1m9qA:
62.6		 5fj3A-1m9qA:
95.17
5fj3B-1m9qA:
95.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		3 / 3 ARG A 187
PRO A 442
ASN A 466
 None
 1.01A 5jwaA-1m9qA:
undetectable
5jwaH-1m9qA:
undetectable		 5jwaA-1m9qA:
19.93
5jwaH-1m9qA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_B_BEZB306_0
(BETA-LACTAMASE VIM-2)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		3 / 3 HIS A 430
ASN A 433
ALA A 437
 None
 0.47A 5n4tB-1m9qA:
undetectable		 5n4tB-1m9qA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NY7_A_NCAA303_0
(AMIDASE)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 6 ARG A 255
GLY A 253
THR A 271
GLU A 272
 None
 1.02A 5ny7A-1m9qA:
undetectable		 5ny7A-1m9qA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_A_ACTA703_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 6 ARG A 179
ALA A 177
PRO A 471
PHE A 172
 None
 1.24A 5odqA-1m9qA:
undetectable		 5odqA-1m9qA:
20.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UO9_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 7 TRP A  74
TRP A 445
PHE A 460
GLU A 463
 None
MPD  A 603 (-4.6A)
MPD  A 603 (-4.2A)
None
 0.25A 5uo9A-1m9qA:
61.0
5uo9B-1m9qA:
63.0		 5uo9A-1m9qA:
100.00
5uo9B-1m9qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UO9_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 7 TRP A  74
TRP A 445
PHE A 460
GLU A 463
 None
MPD  A 603 (-4.6A)
MPD  A 603 (-4.2A)
None
 0.22A 5uo9C-1m9qA:
62.3
5uo9D-1m9qA:
62.7		 5uo9C-1m9qA:
100.00
5uo9D-1m9qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VUN_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 5 GLN A 189
TRP A 356
VAL A 418
SER A 426
 None
HEM  A 901 (-3.6A)
MPD  A 604 (-4.2A)
MPD  A 604 (-3.1A)
 0.75A 5vunA-1m9qA:
59.7		 5vunA-1m9qA:
64.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VUN_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 5 GLY A 186
GLN A 189
TRP A 356
VAL A 418
 MPD  A 604 (-3.8A)
None
HEM  A 901 (-3.6A)
MPD  A 604 (-4.2A)
 0.15A 5vunA-1m9qA:
59.7		 5vunA-1m9qA:
64.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VUN_A_MTLA805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		6 / 8 SER A 246
ARG A 250
ASN A 267
ASN A 338
ASP A 478
TRP A 480
 None
 0.39A 5vunA-1m9qA:
59.7		 5vunA-1m9qA:
64.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VUN_B_ACTB804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 4 GLY A 186
GLN A 189
TRP A 356
VAL A 418
 MPD  A 604 (-3.8A)
None
HEM  A 901 (-3.6A)
MPD  A 604 (-4.2A)
 0.21A 5vunB-1m9qA:
59.2		 5vunB-1m9qA:
64.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VUN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		6 / 8 SER A 246
ARG A 250
ASN A 267
ASN A 338
ASP A 478
TRP A 480
 None
 0.48A 5vunB-1m9qA:
59.2		 5vunB-1m9qA:
64.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VUO_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 4 GLY A 186
GLN A 189
TRP A 356
VAL A 418
 MPD  A 604 (-3.8A)
None
HEM  A 901 (-3.6A)
MPD  A 604 (-4.2A)
 0.14A 5vuoA-1m9qA:
59.7		 5vuoA-1m9qA:
64.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VUO_B_ACTB804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		3 / 3 GLY A 186
TRP A 356
VAL A 418
 MPD  A 604 (-3.8A)
HEM  A 901 (-3.6A)
MPD  A 604 (-4.2A)
 0.11A 5vuoB-1m9qA:
59.3		 5vuoB-1m9qA:
64.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VUO_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		6 / 8 SER A 246
ARG A 250
ASN A 267
ASN A 338
ASP A 478
TRP A 480
 None
 0.48A 5vuoB-1m9qA:
59.3		 5vuoB-1m9qA:
64.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VV7_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 7 SER A 102
VAL A 104
ARG A 365
TRP A 447
 None
MPD  A 605 (-4.7A)
MPD  A 605 ( 4.7A)
MPD  A 605 ( 4.0A)
 0.29A 5vv7A-1m9qA:
62.6
5vv7B-1m9qA:
62.6		 5vv7A-1m9qA:
95.17
5vv7B-1m9qA:
95.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VV9_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 7 TRP A  74
TRP A 445
PHE A 460
GLU A 463
 None
MPD  A 603 (-4.6A)
MPD  A 603 (-4.2A)
None
 0.28A 5vv9A-1m9qA:
61.7
5vv9B-1m9qA:
61.8		 5vv9A-1m9qA:
95.17
5vv9B-1m9qA:
95.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VVA_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 7 TRP A  74
TRP A 445
PHE A 460
GLU A 463
 None
MPD  A 603 (-4.6A)
MPD  A 603 (-4.2A)
None
 0.23A 5vvaA-1m9qA:
32.3
5vvaB-1m9qA:
62.0		 5vvaA-1m9qA:
95.17
5vvaB-1m9qA:
95.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VVD_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 7 TRP A  74
TRP A 445
PHE A 460
GLU A 463
 None
MPD  A 603 (-4.6A)
MPD  A 603 (-4.2A)
None
 0.19A 5vvdA-1m9qA:
61.0
5vvdB-1m9qA:
62.4		 5vvdA-1m9qA:
100.00
5vvdB-1m9qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VVN_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 7 SER A 102
VAL A 104
ARG A 365
TRP A 447
 None
MPD  A 605 (-4.7A)
MPD  A 605 ( 4.7A)
MPD  A 605 ( 4.0A)
 0.27A 5vvnA-1m9qA:
62.2
5vvnB-1m9qA:
62.2		 5vvnA-1m9qA:
95.17
5vvnB-1m9qA:
95.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_D_DAHD60_1
(PUTATIVE CYTOCHROME
C)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 5 HIS A 214
ASN A 245
VAL A 249
LEU A 333
 None
 1.33A 5xdhD-1m9qA:
0.0		 5xdhD-1m9qA:
13.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AUU_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		3 / 3 GLN A 189
TRP A 356
VAL A 418
 None
HEM  A 901 (-3.6A)
MPD  A 604 (-4.2A)
 0.09A 6auuA-1m9qA:
59.2		 6auuA-1m9qA:
64.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 7 TRP A  74
TRP A 445
PHE A 460
GLU A 463
 None
MPD  A 603 (-4.6A)
MPD  A 603 (-4.2A)
None
 0.14A 6auuA-1m9qA:
59.2
6auuB-1m9qA:
59.3		 6auuA-1m9qA:
10.29
6auuB-1m9qA:
10.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AUU_B_ACTB804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 4 GLY A 186
GLN A 189
TRP A 356
VAL A 418
 MPD  A 604 (-3.8A)
None
HEM  A 901 (-3.6A)
MPD  A 604 (-4.2A)
 0.20A 6auuB-1m9qA:
59.3		 6auuB-1m9qA:
64.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AUU_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		6 / 8 SER A 246
ARG A 250
ASN A 267
ASN A 338
ASP A 478
TRP A 480
 None
 0.47A 6auuB-1m9qA:
59.3		 6auuB-1m9qA:
64.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AV6_B_H4BB501_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 7 SER A 102
VAL A 104
ARG A 365
TRP A 447
 None
MPD  A 605 (-4.7A)
MPD  A 605 ( 4.7A)
MPD  A 605 ( 4.0A)
 0.27A 6av6A-1m9qA:
61.5
6av6B-1m9qA:
63.1		 6av6A-1m9qA:
100.00
6av6B-1m9qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AV6_B_H4BB503_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 7 TRP A  74
TRP A 445
PHE A 460
GLU A 463
 None
MPD  A 603 (-4.6A)
MPD  A 603 (-4.2A)
None
 0.12A 6av6A-1m9qA:
61.5
6av6B-1m9qA:
63.1		 6av6A-1m9qA:
100.00
6av6B-1m9qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AV6_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 7 SER A 102
VAL A 104
ARG A 365
TRP A 447
 None
MPD  A 605 (-4.7A)
MPD  A 605 ( 4.7A)
MPD  A 605 ( 4.0A)
 0.35A 6av6C-1m9qA:
62.0
6av6D-1m9qA:
62.9		 6av6C-1m9qA:
100.00
6av6D-1m9qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AV7_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 7 SER A 102
VAL A 104
ARG A 365
TRP A 447
 None
MPD  A 605 (-4.7A)
MPD  A 605 ( 4.7A)
MPD  A 605 ( 4.0A)
 0.27A 6av7A-1m9qA:
61.2
6av7B-1m9qA:
63.3		 6av7A-1m9qA:
100.00
6av7B-1m9qA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_2
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 6 PHE A 231
ARG A 242
ALA A 198
GLN A 294
 None
 1.08A 6b89B-1m9qA:
undetectable		 6b89B-1m9qA:
15.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CIE_B_H4BB502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 7 TRP A  74
TRP A 445
PHE A 460
GLU A 463
 None
MPD  A 603 (-4.6A)
MPD  A 603 (-4.2A)
None
 0.19A 6cieA-1m9qA:
61.3
6cieB-1m9qA:
63.3		 6cieA-1m9qA:
100.00
6cieB-1m9qA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CIF_C_H4BC502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		4 / 7 TRP A  74
TRP A 445
PHE A 460
GLU A 463
 None
MPD  A 603 (-4.6A)
MPD  A 603 (-4.2A)
None
 0.19A 6cifC-1m9qA:
62.1
6cifD-1m9qA:
54.4		 6cifC-1m9qA:
100.00
6cifD-1m9qA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_1
(PEPTIDYLPROLYL
ISOMERASE)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 TYR A 251
PHE A 286
ILE A 362
TRP A 330
TYR A 410
 None
 1.46A 6mkeC-1m9qA:
undetectable		 6mkeC-1m9qA:
8.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_1
(PEPTIDYLPROLYL
ISOMERASE)		 1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE
(Homo
sapiens) 		5 / 10 TYR A 251
PHE A 286
ILE A 362
TRP A 330
TYR A 410
 None
 1.47A 6mkeD-1m9qA:
undetectable		 6mkeD-1m9qA:
8.67