SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1m9u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		 1m9u EARTHWORM
FIBRINOLYTIC ENZYME
(Eisenia
fetida) 		5 / 12 ALA A  83
GLY A  69
THR A  80
LEU A 106
LEU A 108
 None
 1.19A 1jipA-1m9uA:
0.0		 1jipA-1m9uA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_0
(VP39)		 1m9u EARTHWORM
FIBRINOLYTIC ENZYME
(Eisenia
fetida) 		5 / 12 ILE A 181
GLY A 211
GLY A 196
VAL A 162
VAL A 210
 None
 1.06A 1vptA-1m9uA:
undetectable		 1vptA-1m9uA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_F_SPMF1433_1
(NITROALKANE OXIDASE)		 1m9u EARTHWORM
FIBRINOLYTIC ENZYME
(Eisenia
fetida) 		5 / 11 LEU A 114
VAL A  66
ALA A  83
SER A  51
LEU A  46
 None
 1.32A 2c12F-1m9uA:
undetectable		 2c12F-1m9uA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P16_A_GG2A298_1
(COAGULATION FACTOR X
(EC 3.4.21.6)
(STUART FACTOR)
(STUART-PROWER
FACTOR))		 1m9u EARTHWORM
FIBRINOLYTIC ENZYME
(Eisenia
fetida) 		5 / 12 TYR A  99
ALA A 190
SER A 195
TRP A 215
TYR A 228
 None
 0.82A 2p16A-1m9uA:
32.9		 2p16A-1m9uA:
29.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA803_0
(FERROCHELATASE)		 1m9u EARTHWORM
FIBRINOLYTIC ENZYME
(Eisenia
fetida) 		4 / 5 LEU A 123
PRO A 124
LEU A 235
ILE A 238
 None
 0.84A 2qd4A-1m9uA:
undetectable		 2qd4A-1m9uA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1m9u EARTHWORM
FIBRINOLYTIC ENZYME
(Eisenia
fetida) 		5 / 11 THR A 188
ILE A 160
GLY A 189
GLY A 186
PRO A 161
 None
 1.28A 2y7kA-1m9uA:
undetectable		 2y7kA-1m9uA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_C_SALC1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1m9u EARTHWORM
FIBRINOLYTIC ENZYME
(Eisenia
fetida) 		5 / 12 THR A 188
ILE A 160
GLY A 189
GLY A 186
PRO A 161
 None
 1.32A 2y7kC-1m9uA:
undetectable		 2y7kC-1m9uA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1000_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1m9u EARTHWORM
FIBRINOLYTIC ENZYME
(Eisenia
fetida) 		5 / 10 THR A 188
ILE A 160
GLY A 189
GLY A 186
PRO A 161
 None
 1.36A 2y7pA-1m9uA:
undetectable		 2y7pA-1m9uA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC59_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1m9u EARTHWORM
FIBRINOLYTIC ENZYME
(Eisenia
fetida) 		3 / 3 GLY A 197
GLY A 193
GLY A  43
 None
 0.37A 3bogC-1m9uA:
undetectable		 3bogC-1m9uA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_2
(PROTEASE)		 1m9u EARTHWORM
FIBRINOLYTIC ENZYME
(Eisenia
fetida) 		5 / 10 ASP A 185
ILE A  17
GLY A  18
GLY A  19
ILE A 138
 None
 0.99A 3em4V-1m9uA:
undetectable		 3em4V-1m9uA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA279_0
(UNIVERSAL STRESS
PROTEIN)		 1m9u EARTHWORM
FIBRINOLYTIC ENZYME
(Eisenia
fetida) 		4 / 4 SER A 242
SER A  48
THR A  50
SER A  51
 None
 1.32A 3loqA-1m9uA:
undetectable		 3loqA-1m9uA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1m9u EARTHWORM
FIBRINOLYTIC ENZYME
(Eisenia
fetida) 		4 / 4 LEU A 123
PRO A 124
LEU A 235
ILE A 238
 None
 0.92A 4f4dB-1m9uA:
undetectable		 4f4dB-1m9uA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 1m9u EARTHWORM
FIBRINOLYTIC ENZYME
(Eisenia
fetida) 		4 / 4 HIS A 107
GLU A  92
HIS A  91
LEU A 235
 None
 1.46A 4m2rA-1m9uA:
undetectable		 4m2rA-1m9uA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_A_ACTA403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 1m9u EARTHWORM
FIBRINOLYTIC ENZYME
(Eisenia
fetida) 		3 / 3 VAL A 209
LEU A 123
VAL A 231
 None
 0.59A 4wq4A-1m9uA:
undetectable		 4wq4A-1m9uA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 1m9u EARTHWORM
FIBRINOLYTIC ENZYME
(Eisenia
fetida) 		5 / 12 GLY A 196
VAL A 231
ALA A  52
LEU A  53
ALA A 121
 None
 0.90A 5kpcA-1m9uA:
undetectable		 5kpcA-1m9uA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_B_SAMB501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 1m9u EARTHWORM
FIBRINOLYTIC ENZYME
(Eisenia
fetida) 		5 / 12 ALA A 171
GLY A 173
ILE A 163
ASP A 185
GLY A 186
 None
 1.14A 5wwsB-1m9uA:
undetectable		 5wwsB-1m9uA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_0
(NS3 PROTEASE)		 1m9u EARTHWORM
FIBRINOLYTIC ENZYME
(Eisenia
fetida) 		5 / 12 HIS A  57
ASP A 102
GLY A 193
SER A 195
VAL A 217
 None
 0.87A 6c2mC-1m9uA:
10.8		 6c2mC-1m9uA:
15.72