SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ma1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA8_0
(GRAMICIDIN A)		 1ma1 SUPEROXIDE DISMUTASE
(Methanothermobac
ter
thermautotrophic
us) 		3 / 3 VAL A 153
TRP A 131
TRP A 168
 None
 1.43A 1c4dA-1ma1A:
undetectable
1c4dB-1ma1A:
undetectable		 1c4dA-1ma1A:
10.42
1c4dB-1ma1A:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA6_0
(GRAMICIDIN A)		 1ma1 SUPEROXIDE DISMUTASE
(Methanothermobac
ter
thermautotrophic
us) 		3 / 3 ALA A 122
VAL A 133
TRP A 131
 None
 0.85A 1gmkA-1ma1A:
undetectable
1gmkB-1ma1A:
undetectable		 1gmkA-1ma1A:
10.42
1gmkB-1ma1A:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC6_0
(GRAMICIDIN A)		 1ma1 SUPEROXIDE DISMUTASE
(Methanothermobac
ter
thermautotrophic
us) 		3 / 3 ALA A 122
VAL A 133
TRP A 131
 None
 0.88A 1gmkC-1ma1A:
undetectable
1gmkD-1ma1A:
undetectable		 1gmkC-1ma1A:
10.42
1gmkD-1ma1A:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JR1_A_MOAA1332_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 1ma1 SUPEROXIDE DISMUTASE
(Methanothermobac
ter
thermautotrophic
us) 		5 / 11 ASN A  86
MET A  87
GLY A  88
CYH A  93
GLY A  95
 None
 1.40A 1jr1A-1ma1A:
undetectable		 1jr1A-1ma1A:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_A_DVAA6_0
(MINI-GRAMICIDIN A)		 1ma1 SUPEROXIDE DISMUTASE
(Methanothermobac
ter
thermautotrophic
us) 		3 / 3 ALA A  90
VAL A 191
TRP A 188
 None
 1.02A 1tkqA-1ma1A:
undetectable		 1tkqA-1ma1A:
5.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1ma1 SUPEROXIDE DISMUTASE
(Methanothermobac
ter
thermautotrophic
us) 		3 / 3 GLU A  96
GLU A 197
LEU A 143
 None
 0.76A 1v8bB-1ma1A:
undetectable		 1v8bB-1ma1A:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_D_MIXD3539_2
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 1ma1 SUPEROXIDE DISMUTASE
(Methanothermobac
ter
thermautotrophic
us) 		3 / 3 VAL A 191
VAL A 164
ASP A 108
 None
 0.62A 2fumD-1ma1A:
undetectable		 2fumD-1ma1A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_D_DVAD6_0
(GRAMICIDIN D)		 1ma1 SUPEROXIDE DISMUTASE
(Methanothermobac
ter
thermautotrophic
us) 		3 / 3 TRP A 131
ALA A 126
VAL A 148
 None
 0.97A 2izqC-1ma1A:
undetectable
2izqD-1ma1A:
undetectable		 2izqC-1ma1A:
10.42
2izqD-1ma1A:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_A_FOLA401_0
(DIHYDROFOLATE
REDUCTASE)		 1ma1 SUPEROXIDE DISMUTASE
(Methanothermobac
ter
thermautotrophic
us) 		5 / 12 ALA A 132
LEU A 163
PHE A 115
ARG A 114
PRO A  97
 None
 1.11A 2w3bA-1ma1A:
undetectable		 2w3bA-1ma1A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI8_A_HNQA255_1
(CATHEPSIN B)		 1ma1 SUPEROXIDE DISMUTASE
(Methanothermobac
ter
thermautotrophic
us) 		4 / 7 GLY A 130
HIS A  32
HIS A  36
HIS A 151
 None
FE  A 206 (-3.2A)
None
None
 1.17A 3ai8A-1ma1A:
undetectable		 3ai8A-1ma1A:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 1ma1 SUPEROXIDE DISMUTASE
(Methanothermobac
ter
thermautotrophic
us) 		3 / 3 GLY A  75
TRP A 131
VAL A 148
 None
 0.47A 3n62B-1ma1A:
undetectable		 3n62B-1ma1A:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 1ma1 SUPEROXIDE DISMUTASE
(Methanothermobac
ter
thermautotrophic
us) 		3 / 3 GLY A  75
TRP A 131
VAL A 148
 None
 0.44A 3n65B-1ma1A:
undetectable		 3n65B-1ma1A:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 1ma1 SUPEROXIDE DISMUTASE
(Methanothermobac
ter
thermautotrophic
us) 		3 / 3 GLY A  75
TRP A 131
VAL A 148
 None
 0.46A 3n66B-1ma1A:
undetectable		 3n66B-1ma1A:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_B_HAEB1270_1
(COLLAGENASE 3)		 1ma1 SUPEROXIDE DISMUTASE
(Methanothermobac
ter
thermautotrophic
us) 		4 / 5 LEU A  29
HIS A  33
HIS A 170
HIS A  80
 None
None
FE  A 206 (-3.3A)
FE  A 206 (-3.2A)
 1.31A 4a7bB-1ma1A:
undetectable		 4a7bB-1ma1A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_A_ASCA303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 1ma1 SUPEROXIDE DISMUTASE
(Methanothermobac
ter
thermautotrophic
us) 		4 / 7 ILE A  24
TYR A 183
PHE A  83
ASN A  86
 None
 1.43A 4o7gA-1ma1A:
0.9
4o7gB-1ma1A:
1.1		 4o7gA-1ma1A:
20.98
4o7gB-1ma1A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_ACTB804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1ma1 SUPEROXIDE DISMUTASE
(Methanothermobac
ter
thermautotrophic
us) 		3 / 3 GLY A  75
TRP A 131
VAL A 148
 None
 0.45A 5vuoB-1ma1A:
undetectable		 5vuoB-1ma1A:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA607_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 1ma1 SUPEROXIDE DISMUTASE
(Methanothermobac
ter
thermautotrophic
us) 		4 / 4 GLY A  43
ARG A  49
ASN A  45
LEU A  47
 None
 1.32A 6b58A-1ma1A:
0.0		 6b58A-1ma1A:
15.16