SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mab'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_0
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 1mab PROTEIN (F1-ATPASE
BETA CHAIN)
(Rattus
norvegicus) 		5 / 12 TYR B 219
GLY B 185
ALA B 233
ILE B 255
GLN B 308
 None
 1.16A 1nt2A-1mabB:
undetectable		 1nt2A-1mabB:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_1
(TRANSTHYRETIN)		 1mab PROTEIN (F1-ATPASE
BETA CHAIN)
(Rattus
norvegicus) 		4 / 6 LYS B 175
ALA B 174
LEU B 169
VAL B 215
 None
 1.02A 1sn5A-1mabB:
undetectable		 1sn5A-1mabB:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6K_A_ADNA699_1
(CHLORINASE)		 1mab PROTEIN (F1-ATPASE
BETA CHAIN)
(Rattus
norvegicus) 		4 / 7 PHE B 113
TYR B 242
PRO B  85
THR B  90
 None
 1.47A 2q6kA-1mabB:
undetectable		 2q6kA-1mabB:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID5_B_SAMB301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 1mab PROTEIN (F1-ATPASE
BETA CHAIN)
(Rattus
norvegicus) 		5 / 11 TYR B 219
GLY B 185
ALA B 233
ILE B 255
GLN B 308
 None
 1.11A 3id5B-1mabB:
undetectable		 3id5B-1mabB:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID5_B_SAMB301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 1mab PROTEIN (F1-ATPASE
BETA CHAIN)
(Rattus
norvegicus) 		5 / 11 TYR B 219
GLY B 185
ASP B 256
ILE B 255
GLN B 308
 None
None
PO4  B 601 ( 4.4A)
None
None
 1.32A 3id5B-1mabB:
undetectable		 3id5B-1mabB:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID5_F_SAMF301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 1mab PROTEIN (F1-ATPASE
BETA CHAIN)
(Rattus
norvegicus) 		5 / 11 TYR B 219
GLY B 185
ALA B 233
ILE B 255
GLN B 308
 None
 1.11A 3id5F-1mabB:
undetectable		 3id5F-1mabB:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID5_F_SAMF301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 1mab PROTEIN (F1-ATPASE
BETA CHAIN)
(Rattus
norvegicus) 		5 / 11 TYR B 219
GLY B 185
ASP B 256
ILE B 255
GLN B 308
 None
None
PO4  B 601 ( 4.4A)
None
None
 1.31A 3id5F-1mabB:
undetectable		 3id5F-1mabB:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID6_C_SAMC301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 1mab PROTEIN (F1-ATPASE
BETA CHAIN)
(Rattus
norvegicus) 		5 / 12 TYR B 219
GLY B 185
ALA B 233
ILE B 255
GLN B 308
 None
 1.13A 3id6C-1mabB:
undetectable		 3id6C-1mabB:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECLA600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1mab PROTEIN (F1-ATPASE
BETA CHAIN)
PROTEIN (F1-ATPASE
GAMMA CHAIN)
(Rattus
norvegicus) 		5 / 8 LEU B 391
GLY G  76
ALA G 228
THR G  17
ILE G  13
 None
 1.09A 3jusA-1mabB:
undetectable		 3jusA-1mabB:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1mab PROTEIN (F1-ATPASE
BETA CHAIN)
PROTEIN (F1-ATPASE
GAMMA CHAIN)
(Rattus
norvegicus) 		5 / 8 LEU B 391
GLY G  76
ALA G 228
THR G  17
ILE G  13
 None
 1.09A 3jusA-1mabB:
undetectable		 3jusA-1mabB:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECLB600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1mab PROTEIN (F1-ATPASE
BETA CHAIN)
PROTEIN (F1-ATPASE
GAMMA CHAIN)
(Rattus
norvegicus) 		5 / 8 LEU B 391
GLY G  76
ALA G 228
THR G  17
ILE G  13
 None
 1.12A 3jusB-1mabB:
undetectable		 3jusB-1mabB:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECNB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1mab PROTEIN (F1-ATPASE
BETA CHAIN)
PROTEIN (F1-ATPASE
GAMMA CHAIN)
(Rattus
norvegicus) 		5 / 9 LEU B 391
GLY G  76
ALA G 228
THR G  17
ILE G  13
 None
 1.12A 3jusB-1mabB:
undetectable		 3jusB-1mabB:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 1mab PROTEIN (F1-ATPASE
BETA CHAIN)
(Rattus
norvegicus) 		5 / 12 ILE B 108
THR B  90
THR B 110
ILE B  84
PRO B 101
 None
 1.18A 3kpbC-1mabB:
undetectable		 3kpbC-1mabB:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPC_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 1mab PROTEIN (F1-ATPASE
BETA CHAIN)
(Rattus
norvegicus) 		5 / 11 ILE B 108
THR B  90
THR B 110
ILE B  84
PRO B 101
 None
 1.19A 3kpcA-1mabB:
undetectable		 3kpcA-1mabB:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 1mab PROTEIN (F1-ATPASE
BETA CHAIN)
(Rattus
norvegicus) 		5 / 12 ILE B 108
THR B  90
THR B 110
ILE B  84
PRO B 101
 None
 1.11A 3kpdB-1mabB:
undetectable		 3kpdB-1mabB:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 1mab PROTEIN (F1-ATPASE
BETA CHAIN)
(Rattus
norvegicus) 		5 / 12 ILE B  84
THR B 238
ILE B  98
ILE B  82
VAL B  97
 None
 1.04A 3kpdC-1mabB:
undetectable		 3kpdC-1mabB:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXZ_A_0LIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 1mab PROTEIN (F1-ATPASE
BETA CHAIN)
(Rattus
norvegicus) 		5 / 9 LEU B 208
VAL B  97
ILE B 102
MET B 200
VAL B 182
 None
 1.48A 3oxzA-1mabB:
undetectable		 3oxzA-1mabB:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_D_EVPD1_1
(DNA TOPOISOMERASE
2-BETA)		 1mab PROTEIN (F1-ATPASE
BETA CHAIN)
(Rattus
norvegicus) 		4 / 5 GLY B 185
ASP B 256
ARG B 260
GLN B 293
 None
PO4  B 601 ( 4.4A)
None
None
 1.24A 3qx3B-1mabB:
undetectable		 3qx3B-1mabB:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAE_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 1mab PROTEIN (F1-ATPASE
BETA CHAIN)
(Rattus
norvegicus) 		3 / 4 SER B 353
GLY B 161
GLU B 188
 None
ADP  B 604 (-3.2A)
PO4  B 601 (-3.1A)
 0.66A 3raeA-1mabB:
undetectable
3raeC-1mabB:
undetectable		 3raeA-1mabB:
21.90
3raeC-1mabB:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGF_A_BAXA465_2
(CYCLIN-DEPENDENT
KINASE 8)		 1mab PROTEIN (F1-ATPASE
BETA CHAIN)
(Rattus
norvegicus) 		4 / 7 LEU B  69
VAL B  16
VAL B  38
LEU B 271
 None
 0.93A 3rgfA-1mabB:
undetectable		 3rgfA-1mabB:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA609_0
(GBAA_1210 PROTEIN)		 1mab PROTEIN (F1-ATPASE
BETA CHAIN)
(Rattus
norvegicus) 		3 / 3 LYS B 430
VAL B 460
HIS B 427
 None
 1.18A 3tj7A-1mabB:
undetectable		 3tj7A-1mabB:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTP_A_ASCA802_0
(RRNA N-GLYCOSIDASE)		 1mab PROTEIN (F1-ATPASE
BETA CHAIN)
(Rattus
norvegicus) 		4 / 5 ILE B 102
ASN B 194
TYR B 197
ILE B  94
 None
 0.93A 4jtpA-1mabB:
undetectable		 4jtpA-1mabB:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8Y_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1mab PROTEIN (F1-ATPASE
BETA CHAIN)
(Rattus
norvegicus) 		5 / 12 GLU B 100
ASN B  96
ALA B 216
PHE B 243
VAL B 182
 None
 1.15A 4u8yB-1mabB:
undetectable		 4u8yB-1mabB:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 1mab PROTEIN (F1-ATPASE
BETA CHAIN)
(Rattus
norvegicus) 		5 / 9 TYR B 311
ILE B 310
GLY B 156
GLU B 188
ARG B 260
 None
None
None
PO4  B 601 (-3.1A)
None
 1.38A 4yp2B-1mabB:
undetectable		 4yp2B-1mabB:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CR1_A_T44A201_1
(TRANSTHYRETIN)		 1mab PROTEIN (F1-ATPASE
BETA CHAIN)
(Rattus
norvegicus) 		4 / 5 LYS B 175
ALA B 174
LEU B 169
VAL B 215
 None
 1.00A 5cr1A-1mabB:
undetectable		 5cr1A-1mabB:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1802_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1mab PROTEIN (F1-ATPASE
BETA CHAIN)
(Rattus
norvegicus) 		4 / 7 SER B  78
PHE B  25
HIS B  52
ILE B  32
 None
 1.14A 5vkqA-1mabB:
undetectable
5vkqB-1mabB:
undetectable		 5vkqA-1mabB:
15.56
5vkqB-1mabB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1mab PROTEIN (F1-ATPASE
BETA CHAIN)
(Rattus
norvegicus) 		4 / 8 SER B  78
PHE B  25
HIS B  52
ILE B  32
 None
 1.12A 5vkqB-1mabB:
undetectable
5vkqC-1mabB:
undetectable		 5vkqB-1mabB:
15.56
5vkqC-1mabB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1mab PROTEIN (F1-ATPASE
BETA CHAIN)
(Rattus
norvegicus) 		4 / 7 SER B  78
PHE B  25
HIS B  52
ILE B  32
 None
 1.11A 5vkqC-1mabB:
undetectable
5vkqD-1mabB:
undetectable		 5vkqC-1mabB:
15.56
5vkqD-1mabB:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7P_A_SAMA501_0
(OXAC)		 1mab PROTEIN (F1-ATPASE
BETA CHAIN)
(Rattus
norvegicus) 		5 / 12 GLU B  48
ALA B 230
GLY B 227
LEU B 234
PHE B 261
 None
 1.12A 5w7pA-1mabB:
undetectable		 5w7pA-1mabB:
23.33