SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mai'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LM8_B_VIBB223_1 (THIAMINE PYROPHOSPHOKINASE)	1mai	PHOSPHOLIPASE C DELTA-1 (Rattus norvegicus)	4 / 7	TYR A 42 LEU A 22 LEU A 125 THR A 107	None	1.00A	3lm8B-1maiA: undetectable 3lm8D-1maiA: undetectable	3lm8B-1maiA: 21.46 3lm8D-1maiA: 21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWD_A_377A402_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	1mai	PHOSPHOLIPASE C DELTA-1 (Rattus norvegicus)	5 / 9	ALA A 116 SER A 114 ALA A 21 SER A 26 ALA A 118	None	1.28A	4twdA-1maiA: 0.0 4twdB-1maiA: 0.0 4twdC-1maiA: 0.0 4twdD-1maiA: 0.0 4twdE-1maiA: 0.0	4twdA-1maiA: 17.80 4twdB-1maiA: 17.80 4twdC-1maiA: 17.80 4twdD-1maiA: 17.80 4twdE-1maiA: 17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWD_A_377A402_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	1mai	PHOSPHOLIPASE C DELTA-1 (Rattus norvegicus)	5 / 9	SER A 26 ALA A 118 ALA A 116 SER A 114 ALA A 21	None	1.27A	4twdA-1maiA: 0.0 4twdB-1maiA: 0.0 4twdC-1maiA: 0.0 4twdD-1maiA: 0.0 4twdE-1maiA: 0.0	4twdA-1maiA: 17.80 4twdB-1maiA: 17.80 4twdC-1maiA: 17.80 4twdD-1maiA: 17.80 4twdE-1maiA: 17.80

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3LM8_B_VIBB223_1","THIAMINE PYROPHOSPHOKINASE;THIAMINE PYROPHOSPHOKINASE","1mai","PHOSPHOLIPASE C DELTA-1","Rattus norvegicus",4,"TYR A  42;LEU A  22;LEU A 125;THR A 107","None","1.00A","3lm8B-1maiA:undetectable;3lm8D-1maiA:undetectable","3lm8B-1maiA:21.46;3lm8D-1maiA:21.46"],["4TWD_A_377A402_1","CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL","1mai","PHOSPHOLIPASE C DELTA-1","Rattus norvegicus",5,"ALA A 116;SER A 114;ALA A  21;SER A  26;ALA A 118","None","1.28A","4twdA-1maiA:0.0;4twdB-1maiA:0.0;4twdC-1maiA:0.0;4twdD-1maiA:0.0;4twdE-1maiA:0.0","4twdA-1maiA:17.80;4twdB-1maiA:17.80;4twdC-1maiA:17.80;4twdD-1maiA:17.80;4twdE-1maiA:17.80"],["4TWD_A_377A402_1","CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL","1mai","PHOSPHOLIPASE C DELTA-1","Rattus norvegicus",5,"SER A  26;ALA A 118;ALA A 116;SER A 114;ALA A  21","None","1.27A","4twdA-1maiA:0.0;4twdB-1maiA:0.0;4twdC-1maiA:0.0;4twdD-1maiA:0.0;4twdE-1maiA:0.0","4twdA-1maiA:17.80;4twdB-1maiA:17.80;4twdC-1maiA:17.80;4twdD-1maiA:17.80;4twdE-1maiA:17.80"]]