SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mam'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAV_A_RAVA183_1
(FERRITIN LIGHT CHAIN)
1mam IGG2B-KAPPA YST9.1
FAB (HEAVY CHAIN)

(Mus
musculus)
4 / 6 LEU H  48
SER H  63
TYR H  62
ALA H  64
None
1.02A 3ravA-1mamH:
undetectable
3ravA-1mamH:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)
1mam IGG2B-KAPPA YST9.1
FAB (HEAVY CHAIN)

(Mus
musculus)
4 / 5 THR H  87
GLY H  16
VAL H  12
PRO H  14
None
0.85A 4grkA-1mamH:
undetectable
4grkA-1mamH:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMA_A_CXXA603_1
(TRANSPORTER)
1mam IGG2B-KAPPA YST9.1
FAB (HEAVY CHAIN)

(Mus
musculus)
5 / 11 PRO H 129
VAL H 127
SER H 185
SER H 184
THR H 211
None
1.31A 4mmaA-1mamH:
undetectable
4mmaA-1mamH:
19.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MTH_A_ACTA302_0
(ANTIBODY FAB HEAVY
CHAIN)
1mam IGG2B-KAPPA YST9.1
FAB (HEAVY CHAIN)

(Mus
musculus)
4 / 5 SER H 118
ALA H 120
PHE H 152
LEU H 176
None
0.40A 5mthA-1mamH:
24.5
5mthA-1mamH:
63.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGJ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
1mam IGG2B-KAPPA YST9.1
FAB (HEAVY CHAIN)

(Mus
musculus)
3 / 3 VAL H 142
VAL H 189
GLN H 197
None
0.58A 5qgjA-1mamH:
undetectable
5qgjA-1mamH:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
1mam IGG2B-KAPPA YST9.1
FAB (HEAVY CHAIN)

(Mus
musculus)
3 / 3 VAL H 142
VAL H 189
GLN H 197
None
0.57A 5qglA-1mamH:
undetectable
5qglA-1mamH:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGM_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
1mam IGG2B-KAPPA YST9.1
FAB (HEAVY CHAIN)

(Mus
musculus)
3 / 3 VAL H 142
VAL H 189
GLN H 197
None
0.63A 5qgmA-1mamH:
0.0
5qgmA-1mamH:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
1mam IGG2B-KAPPA YST9.1
FAB (HEAVY CHAIN)

(Mus
musculus)
3 / 3 VAL H 142
VAL H 189
GLN H 197
None
0.61A 5qgnA-1mamH:
0.0
5qgnA-1mamH:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
1mam IGG2B-KAPPA YST9.1
FAB (HEAVY CHAIN)

(Mus
musculus)
3 / 3 VAL H 142
VAL H 189
GLN H 197
None
0.62A 5qguA-1mamH:
undetectable
5qguA-1mamH:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
1mam IGG2B-KAPPA YST9.1
FAB (HEAVY CHAIN)

(Mus
musculus)
3 / 3 VAL H 142
VAL H 189
GLN H 197
None
0.67A 5qgvA-1mamH:
undetectable
5qgvA-1mamH:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
1mam IGG2B-KAPPA YST9.1
FAB (HEAVY CHAIN)

(Mus
musculus)
3 / 3 VAL H 142
VAL H 189
GLN H 197
None
0.69A 5qgwA-1mamH:
undetectable
5qgwA-1mamH:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
1mam IGG2B-KAPPA YST9.1
FAB (HEAVY CHAIN)

(Mus
musculus)
3 / 3 VAL H 142
VAL H 189
GLN H 197
None
0.68A 5qgxA-1mamH:
undetectable
5qgxA-1mamH:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH0_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
1mam IGG2B-KAPPA YST9.1
FAB (HEAVY CHAIN)

(Mus
musculus)
3 / 3 VAL H 142
VAL H 189
GLN H 197
None
0.67A 5qh0A-1mamH:
undetectable
5qh0A-1mamH:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
1mam IGG2B-KAPPA YST9.1
FAB (HEAVY CHAIN)

(Mus
musculus)
3 / 3 VAL H 142
VAL H 189
GLN H 197
None
0.70A 5qh1A-1mamH:
undetectable
5qh1A-1mamH:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
1mam IGG2B-KAPPA YST9.1
FAB (HEAVY CHAIN)

(Mus
musculus)
3 / 3 VAL H 142
VAL H 189
GLN H 197
None
0.66A 5qh4A-1mamH:
undetectable
5qh4A-1mamH:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
1mam IGG2B-KAPPA YST9.1
FAB (HEAVY CHAIN)

(Mus
musculus)
3 / 3 VAL H 142
VAL H 189
GLN H 197
None
0.67A 5qh7A-1mamH:
undetectable
5qh7A-1mamH:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
1mam IGG2B-KAPPA YST9.1
FAB (HEAVY CHAIN)

(Mus
musculus)
3 / 3 VAL H 142
VAL H 189
GLN H 197
None
0.66A 5qh9A-1mamH:
undetectable
5qh9A-1mamH:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
1mam IGG2B-KAPPA YST9.1
FAB (HEAVY CHAIN)

(Mus
musculus)
3 / 3 VAL H 142
VAL H 189
GLN H 197
None
0.65A 5qhcA-1mamH:
undetectable
5qhcA-1mamH:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
1mam IGG2B-KAPPA YST9.1
FAB (HEAVY CHAIN)

(Mus
musculus)
3 / 3 VAL H 142
VAL H 189
GLN H 197
None
0.65A 5qheA-1mamH:
undetectable
5qheA-1mamH:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
1mam IGG2B-KAPPA YST9.1
FAB (HEAVY CHAIN)

(Mus
musculus)
3 / 3 VAL H 142
VAL H 189
GLN H 197
None
0.67A 5qhfA-1mamH:
undetectable
5qhfA-1mamH:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
1mam IGG2B-KAPPA YST9.1
FAB (HEAVY CHAIN)

(Mus
musculus)
3 / 3 VAL H 142
VAL H 189
GLN H 197
None
0.65A 5qhgA-1mamH:
undetectable
5qhgA-1mamH:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
1mam IGG2B-KAPPA YST9.1
FAB (HEAVY CHAIN)

(Mus
musculus)
3 / 3 VAL H 142
VAL H 189
GLN H 197
None
0.67A 5qhhA-1mamH:
0.0
5qhhA-1mamH:
19.57