SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mbm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_B_DVAB8_0
(GRAMICIDIN A)		 1mbm CHYMOTRYPSIN-LIKE
SERINE PROTEASE
(Equine
arteritis
virus) 		3 / 3 VAL A  32
VAL A  34
TRP A  80
 None
 0.66A 1av2A-1mbmA:
undetectable
1av2B-1mbmA:
undetectable		 1av2A-1mbmA:
12.94
1av2B-1mbmA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OQ5_A_CELA701_2
(CARBONIC ANHYDRASE
II)		 1mbm CHYMOTRYPSIN-LIKE
SERINE PROTEASE
(Equine
arteritis
virus) 		4 / 4 HIS A  39
VAL A  40
THR A 146
LEU A  35
 None
 1.25A 1oq5A-1mbmA:
0.0		 1oq5A-1mbmA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_C_DVAC8_0
(GRAMICIDIN D)		 1mbm CHYMOTRYPSIN-LIKE
SERINE PROTEASE
(Equine
arteritis
virus) 		3 / 3 VAL A  34
TRP A  80
VAL A  32
 None
 0.91A 2izqC-1mbmA:
undetectable
2izqD-1mbmA:
undetectable		 2izqC-1mbmA:
12.94
2izqD-1mbmA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6P_B_TA1B502_1
(TUBULIN BETA CHAIN)		 1mbm CHYMOTRYPSIN-LIKE
SERINE PROTEASE
(Equine
arteritis
virus) 		5 / 12 VAL A 133
PHE A  60
THR A  71
GLY A  13
LEU A  49
 None
 1.16A 3j6pB-1mbmA:
undetectable		 3j6pB-1mbmA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_0
(16S RRNA METHYLASE)		 1mbm CHYMOTRYPSIN-LIKE
SERINE PROTEASE
(Equine
arteritis
virus) 		5 / 12 GLY A  23
GLY A 121
LEU A  35
THR A  48
LEU A  49
 None
 1.00A 3p2kA-1mbmA:
undetectable		 3p2kA-1mbmA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_B_SAMB6735_0
(16S RRNA METHYLASE)		 1mbm CHYMOTRYPSIN-LIKE
SERINE PROTEASE
(Equine
arteritis
virus) 		5 / 12 GLY A  23
GLY A 121
LEU A  35
THR A  48
LEU A  49
 None
 1.11A 3p2kB-1mbmA:
undetectable		 3p2kB-1mbmA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_C_UEGC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 1mbm CHYMOTRYPSIN-LIKE
SERINE PROTEASE
(Equine
arteritis
virus) 		5 / 10 GLY A  23
ALA A  37
GLY A 121
VAL A  15
HIS A  39
 None
 1.44A 4c5lC-1mbmA:
undetectable		 4c5lC-1mbmA:
25.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA502_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 1mbm CHYMOTRYPSIN-LIKE
SERINE PROTEASE
(Equine
arteritis
virus) 		4 / 8 LEU A  58
VAL A  34
VAL A  32
GLN A  73
 None
 0.80A 4em2A-1mbmA:
undetectable		 4em2A-1mbmA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LZR_A_LOCA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 1mbm CHYMOTRYPSIN-LIKE
SERINE PROTEASE
(Equine
arteritis
virus) 		4 / 8 VAL A 189
LEU A 193
ASP A 177
ILE A 178
 None
 0.88A 4lzrA-1mbmA:
undetectable		 4lzrA-1mbmA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM6_A_29EA603_1
(TRANSPORTER)		 1mbm CHYMOTRYPSIN-LIKE
SERINE PROTEASE
(Equine
arteritis
virus) 		5 / 12 ASP A 119
PHE A  14
VAL A  15
SER A 122
GLY A  23
 None
 1.17A 4mm6A-1mbmA:
undetectable		 4mm6A-1mbmA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM6_A_29EA603_1
(TRANSPORTER)		 1mbm CHYMOTRYPSIN-LIKE
SERINE PROTEASE
(Equine
arteritis
virus) 		5 / 12 VAL A 133
ALA A 123
VAL A  15
GLY A  23
THR A 135
 None
 1.32A 4mm6A-1mbmA:
undetectable		 4mm6A-1mbmA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 1mbm CHYMOTRYPSIN-LIKE
SERINE PROTEASE
(Equine
arteritis
virus) 		5 / 12 VAL A 133
ALA A  67
PHE A  60
THR A  71
GLY A  13
 None
 1.13A 5m54E-1mbmA:
undetectable		 5m54E-1mbmA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 1mbm CHYMOTRYPSIN-LIKE
SERINE PROTEASE
(Equine
arteritis
virus) 		5 / 12 VAL A 133
PHE A  60
THR A  71
GLY A  13
LEU A  49
 None
 1.15A 5m54E-1mbmA:
undetectable		 5m54E-1mbmA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5C_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 1mbm CHYMOTRYPSIN-LIKE
SERINE PROTEASE
(Equine
arteritis
virus) 		5 / 12 VAL A 133
ALA A  67
THR A  71
GLY A  13
LEU A  49
 None
 1.11A 5m5cB-1mbmA:
undetectable		 5m5cB-1mbmA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGC_B_TA1B601_1
(TUBULIN BETA CHAIN)		 1mbm CHYMOTRYPSIN-LIKE
SERINE PROTEASE
(Equine
arteritis
virus) 		5 / 12 VAL A 133
PHE A  60
THR A  71
GLY A  13
LEU A  49
 None
 1.06A 5ogcB-1mbmA:
undetectable		 5ogcB-1mbmA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_1
(SERUM ALBUMIN)		 1mbm CHYMOTRYPSIN-LIKE
SERINE PROTEASE
(Equine
arteritis
virus) 		4 / 5 ASN A  30
VAL A  34
LEU A  58
SER A  74
 None
 1.28A 6a7pA-1mbmA:
undetectable		 6a7pA-1mbmA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DYN_A_HSMA901_0
(EBONY)		 1mbm CHYMOTRYPSIN-LIKE
SERINE PROTEASE
(Equine
arteritis
virus) 		4 / 4 GLU A 109
VAL A 158
LEU A 163
THR A  90
 None
 1.32A 6dynA-1mbmA:
0.0		 6dynA-1mbmA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DYO_A_LDPA901_0
(EBONY)		 1mbm CHYMOTRYPSIN-LIKE
SERINE PROTEASE
(Equine
arteritis
virus) 		4 / 5 GLU A 109
VAL A 158
LEU A 163
THR A  90
 None
 1.37A 6dyoA-1mbmA:
0.0		 6dyoA-1mbmA:
19.75