SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mbs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4S_A_TPVA201_2
(PROTEIN (HIV-1
PROTEASE))		 1mbs MYOGLOBIN
(Phoca
vitulina) 		4 / 8 LEU A  11
ALA A 134
ILE A 111
VAL A  10
 None
 0.79A 1d4sB-1mbsA:
undetectable		 1d4sB-1mbsA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Z_A_COCA301_1
(CHIMERA OF IG KAPPA
CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION)		 1mbs MYOGLOBIN
(Phoca
vitulina) 		4 / 8 LEU A   9
LEU A  76
GLU A 122
TRP A  14
 None
 1.12A 1i7zA-1mbsA:
undetectable		 1i7zA-1mbsA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_A_NPSA5_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 1mbs MYOGLOBIN
(Phoca
vitulina) 		5 / 12 LEU A 115
LEU A 135
VAL A  13
GLY A  15
LEU A  76
 None
 1.08A 3nt1A-1mbsA:
undetectable		 3nt1A-1mbsA:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDA_A_RLTA403_1
(MARINER MOS1
TRANSPOSASE)		 1mbs MYOGLOBIN
(Phoca
vitulina) 		4 / 6 ASP A 141
ASN A 140
ALA A 143
TYR A 146
 None
 1.07A 4mdaA-1mbsA:
undetectable		 4mdaA-1mbsA:
21.62