SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mc3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GM7_B_PNNB1577_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 1mc3 GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Escherichia
coli) 		4 / 8 SER A 102
ALA A  89
PHE A  90
ILE A  52
 None
 1.10A 1gm7A-1mc3A:
0.0
1gm7B-1mc3A:
0.0		 1gm7A-1mc3A:
18.95
1gm7B-1mc3A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_A_MIYA2001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1mc3 GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Escherichia
coli) 		4 / 8 PHE A  96
GLY A  93
ILE A  52
ALA A  78
 None
 0.84A 3aodA-1mc3A:
undetectable		 3aodA-1mc3A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCS_A_BAXA401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 1mc3 GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Escherichia
coli) 		4 / 6 VAL A 105
LEU A 195
ILE A  46
ILE A   5
 None
 0.93A 3gcsA-1mc3A:
undetectable		 3gcsA-1mc3A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SU9_A_ACTA426_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1mc3 GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Escherichia
coli) 		3 / 3 GLN A  62
GLU A  79
LYS A  58
 None
 0.88A 3su9A-1mc3A:
undetectable		 3su9A-1mc3A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 1mc3 GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Escherichia
coli) 		5 / 9 LEU A 104
ILE A   4
ILE A   5
TYR A  35
ILE A  52
 None
 1.03A 3zosA-1mc3A:
undetectable		 3zosA-1mc3A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_A_STRA601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 1mc3 GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Escherichia
coli) 		4 / 6 ALA A 184
ILE A  52
GLY A  93
ILE A 200
 None
 0.82A 4r21A-1mc3A:
undetectable		 4r21A-1mc3A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 1mc3 GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Escherichia
coli) 		4 / 7 LYS A  58
TYR A  60
LEU A  65
PHE A  71
 None
 1.24A 4yv5A-1mc3A:
undetectable		 4yv5A-1mc3A:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 1mc3 GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Escherichia
coli) 		4 / 7 LYS A  58
TYR A  60
LEU A  65
PHE A  71
 None
 1.14A 4yv5B-1mc3A:
undetectable		 4yv5B-1mc3A:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA602_1
(SERUM ALBUMIN)		 1mc3 GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Escherichia
coli) 		5 / 12 PHE A 219
LEU A 215
GLY A 115
SER A 117
LEU A 120
 None
 1.44A 4zbrA-1mc3A:
undetectable		 4zbrA-1mc3A:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_B_DB8B800_1
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 1mc3 GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Escherichia
coli) 		5 / 10 ALA A  89
ILE A  92
PHE A  90
LEU A  50
ALA A  78
 None
 1.25A 5ajqB-1mc3A:
undetectable		 5ajqB-1mc3A:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_1
(SCRFP-TAG,GP41)		 1mc3 GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Escherichia
coli) 		5 / 12 GLN A 280
LEU A 282
LEU A 283
GLU A 284
LEU A 285
 None
 0.75A 5nwwA-1mc3A:
0.0		 5nwwA-1mc3A:
9.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EFN_A_SAMA501_0
(SPORULATION KILLING
FACTOR MATURATION
PROTEIN SKFB)		 1mc3 GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Escherichia
coli) 		5 / 11 TYR A 204
PHE A  90
SER A 102
THR A 131
LEU A 210
 None
 1.48A 6efnA-1mc3A:
undetectable		 6efnA-1mc3A:
21.52