SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1md6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB514_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 1md6 INTERLEUKIN 1
FAMILY, MEMBER 5
(DELTA)
(Mus
musculus) 		5 / 12 ILE A  84
LEU A  79
SER A  42
ILE A  41
LEU A  25
 None
 1.15A 3k2hB-1md6A:
undetectable		 3k2hB-1md6A:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_3
(NS3 PROTEASE, NS4A
PROTEIN)		 1md6 INTERLEUKIN 1
FAMILY, MEMBER 5
(DELTA)
(Mus
musculus) 		4 / 5 SER A  42
PRO A  45
TYR A  88
VAL A  56
 None
 1.35A 3sufC-1md6A:
undetectable		 3sufC-1md6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1md6 INTERLEUKIN 1
FAMILY, MEMBER 5
(DELTA)
(Mus
musculus) 		4 / 5 GLY A  62
GLY A  63
ASN A  83
GLU A  40
 None
 0.80A 4fglC-1md6A:
undetectable		 4fglC-1md6A:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1md6 INTERLEUKIN 1
FAMILY, MEMBER 5
(DELTA)
(Mus
musculus) 		4 / 6 GLY A  62
GLY A  63
ASN A  83
GLU A  40
 None
 0.90A 4fglD-1md6A:
undetectable		 4fglD-1md6A:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_B_ADNB503_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 1md6 INTERLEUKIN 1
FAMILY, MEMBER 5
(DELTA)
(Mus
musculus) 		4 / 5 LEU A  79
VAL A  60
GLU A  39
LEU A  20
 None
 1.01A 5xooB-1md6A:
0.0		 5xooB-1md6A:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_C_ADNC502_2
(-)		 1md6 INTERLEUKIN 1
FAMILY, MEMBER 5
(DELTA)
(Mus
musculus) 		4 / 4 GLN A 151
THR A 107
THR A 122
LEU A  15
 None
 1.32A 6f3mC-1md6A:
undetectable		 6f3mC-1md6A:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_2
(-)		 1md6 INTERLEUKIN 1
FAMILY, MEMBER 5
(DELTA)
(Mus
musculus) 		4 / 5 GLN A 151
THR A 107
THR A 122
LEU A  15
 None
 1.36A 6gbnB-1md6A:
undetectable		 6gbnB-1md6A:
15.81