SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mda'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_A_RBFA301_1
(PROTEIN (FLAVODOXIN))
1mda METHYLAMINE
DEHYDROGENASE (HEAVY
SUBUNIT)

(Paracoccus
denitrificans)
4 / 7 THR H  37
ASN H  48
THR H  45
GLY H  64
None
0.99A 1bu5A-1mdaH:
undetectable
1bu5A-1mdaH:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3002_1
(SERUM ALBUMIN)
1mda METHYLAMINE
DEHYDROGENASE (HEAVY
SUBUNIT)

(Paracoccus
denitrificans)
4 / 8 LEU H  81
ARG H 119
TYR H  97
SER H  85
None
1.11A 1hk3A-1mdaH:
undetectable
1hk3A-1mdaH:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA444_1
(ALPHA AMYLASE)
1mda METHYLAMINE
DEHYDROGENASE (LIGHT
SUBUNIT)

(Paracoccus
denitrificans)
4 / 7 TYR L 117
ASN L 103
GLY L  93
TRP L  13
None
1.36A 1mxgA-1mdaL:
undetectable
1mxgA-1mdaL:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
1mda AMICYANIN
(Paracoccus
denitrificans)
4 / 4 HIS A  53
CYH A  92
HIS A  95
MET A  98
CU  A   0 ( 2.9A)
CU  A   0 ( 2.1A)
CU  A   0 ( 3.1A)
CU  A   0 ( 2.8A)
0.53A 1oe1A-1mdaA:
3.3
1oe1A-1mdaA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
1mda AMICYANIN
(Paracoccus
denitrificans)
5 / 5 HIS A  53
CYH A  92
PRO A  94
HIS A  95
MET A  98
CU  A   0 ( 2.9A)
CU  A   0 ( 2.1A)
None
CU  A   0 ( 3.1A)
CU  A   0 ( 2.8A)
0.76A 1oe2A-1mdaA:
5.1
1oe2A-1mdaA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
1mda AMICYANIN
(Paracoccus
denitrificans)
4 / 4 HIS A  53
CYH A  92
HIS A  95
MET A  98
CU  A   0 ( 2.9A)
CU  A   0 ( 2.1A)
CU  A   0 ( 3.1A)
CU  A   0 ( 2.8A)
0.56A 1oe3A-1mdaA:
undetectable
1oe3A-1mdaA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q13_A_TESA501_1
(PROSTAGLANDIN-E2
9-REDUCTASE)
1mda METHYLAMINE
DEHYDROGENASE (HEAVY
SUBUNIT)

(Paracoccus
denitrificans)
4 / 6 HIS H 169
GLU H 360
PRO H  39
VAL H 122
None
1.43A 1q13A-1mdaH:
undetectable
1q13A-1mdaH:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQD_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)
1mda AMICYANIN
(Paracoccus
denitrificans)
4 / 4 HIS A  53
CYH A  92
HIS A  95
MET A  98
CU  A   0 ( 2.9A)
CU  A   0 ( 2.1A)
CU  A   0 ( 3.1A)
CU  A   0 ( 2.8A)
0.74A 2fqdA-1mdaA:
undetectable
2fqdA-1mdaA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)
1mda AMICYANIN
(Paracoccus
denitrificans)
4 / 4 HIS A  53
CYH A  92
HIS A  95
MET A  98
CU  A   0 ( 2.9A)
CU  A   0 ( 2.1A)
CU  A   0 ( 3.1A)
CU  A   0 ( 2.8A)
0.67A 2fqeA-1mdaA:
3.0
2fqeA-1mdaA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)
1mda AMICYANIN
(Paracoccus
denitrificans)
4 / 4 HIS A  53
CYH A  92
HIS A  95
MET A  98
CU  A   0 ( 2.9A)
CU  A   0 ( 2.1A)
CU  A   0 ( 3.1A)
CU  A   0 ( 2.8A)
0.70A 2fqfA-1mdaA:
undetectable
2fqfA-1mdaA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)
1mda AMICYANIN
(Paracoccus
denitrificans)
4 / 4 HIS A  53
CYH A  92
HIS A  95
MET A  98
CU  A   0 ( 2.9A)
CU  A   0 ( 2.1A)
CU  A   0 ( 3.1A)
CU  A   0 ( 2.8A)
0.70A 2fqgA-1mdaA:
3.0
2fqgA-1mdaA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VJ1_A_BEZA1303_0
(SARS CORONAVIRUS
MAIN PROTEINASE)
1mda AMICYANIN
(Paracoccus
denitrificans)
3 / 3 HIS A  95
MET A  98
MET A  51
CU  A   0 ( 3.1A)
CU  A   0 ( 2.8A)
None
1.44A 2vj1A-1mdaA:
0.0
2vj1A-1mdaA:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1337_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
1mda AMICYANIN
(Paracoccus
denitrificans)
4 / 4 HIS A  53
CYH A  92
HIS A  95
MET A  98
CU  A   0 ( 2.9A)
CU  A   0 ( 2.1A)
CU  A   0 ( 3.1A)
CU  A   0 ( 2.8A)
0.56A 2xxgA-1mdaA:
5.5
2xxgA-1mdaA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
1mda AMICYANIN
(Paracoccus
denitrificans)
5 / 5 HIS A  53
CYH A  92
PRO A  94
HIS A  95
MET A  98
CU  A   0 ( 2.9A)
CU  A   0 ( 2.1A)
None
CU  A   0 ( 3.1A)
CU  A   0 ( 2.8A)
0.81A 2xxgC-1mdaA:
5.5
2xxgC-1mdaA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LTW_A_HLZA300_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)
1mda AMICYANIN
(Paracoccus
denitrificans)
4 / 6 PHE A  57
TYR A  88
VAL A  23
PHE A  82
None
1.35A 3ltwA-1mdaA:
undetectable
3ltwA-1mdaA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_1
(SAM-DEPENDENT
METHYLTRANSFERASE)
1mda METHYLAMINE
DEHYDROGENASE (HEAVY
SUBUNIT)

(Paracoccus
denitrificans)
4 / 4 GLY H 255
GLU H 253
ASP H 250
ASP H 259
None
1.06A 3mb5A-1mdaH:
undetectable
3mb5A-1mdaH:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_0
(2'-O-METHYL
TRANSFERASE)
1mda METHYLAMINE
DEHYDROGENASE (HEAVY
SUBUNIT)

(Paracoccus
denitrificans)
5 / 12 GLY H 236
PRO H 222
GLY H 223
LEU H 234
MET H 245
None
1.49A 3r24A-1mdaH:
undetectable
3r24A-1mdaH:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1001_0
(BLUE COPPER OXIDASE
CUEO)
1mda AMICYANIN
(Paracoccus
denitrificans)
4 / 4 HIS A  53
CYH A  92
HIS A  95
MET A  98
CU  A   0 ( 2.9A)
CU  A   0 ( 2.1A)
CU  A   0 ( 3.1A)
CU  A   0 ( 2.8A)
0.70A 4ef3A-1mdaA:
undetectable
4ef3A-1mdaA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_D_D16D402_1
(THYMIDYLATE SYNTHASE)
1mda METHYLAMINE
DEHYDROGENASE (HEAVY
SUBUNIT)

(Paracoccus
denitrificans)
4 / 8 LYS H 271
TYR H 221
ASP H 237
GLY H 223
None
0.87A 4iqqD-1mdaH:
undetectable
4iqqD-1mdaH:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)
1mda METHYLAMINE
DEHYDROGENASE (HEAVY
SUBUNIT)

(Paracoccus
denitrificans)
4 / 5 GLY H  76
SER H 135
GLU H 367
ASP H  78
None
1.28A 4xueA-1mdaH:
undetectable
4xueA-1mdaH:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
1mda METHYLAMINE
DEHYDROGENASE (HEAVY
SUBUNIT)
METHYLAMINE
DEHYDROGENASE (LIGHT
SUBUNIT)

(Paracoccus
denitrificans)
4 / 5 ALA L 102
HIS H 178
PRO H 184
PHE H 141
None
1.28A 4ze2A-1mdaL:
0.0
4ze2A-1mdaL:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_A_SALA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
1mda METHYLAMINE
DEHYDROGENASE (HEAVY
SUBUNIT)

(Paracoccus
denitrificans)
4 / 8 VAL H  98
LEU H 161
GLY H 150
SER H 152
None
0.80A 5f1aA-1mdaH:
0.0
5f1aA-1mdaH:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_A_IPHA101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)
1mda METHYLAMINE
DEHYDROGENASE (HEAVY
SUBUNIT)

(Paracoccus
denitrificans)
4 / 5 CYH H 167
CYH H 183
LEU H 180
HIS H 169
None
1.48A 5hrqA-1mdaH:
undetectable
5hrqB-1mdaH:
undetectable
5hrqF-1mdaH:
undetectable
5hrqA-1mdaH:
9.77
5hrqB-1mdaH:
7.69
5hrqF-1mdaH:
7.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_C_IPHC101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)
1mda METHYLAMINE
DEHYDROGENASE (HEAVY
SUBUNIT)

(Paracoccus
denitrificans)
4 / 5 CYH H 167
CYH H 183
LEU H 180
HIS H 169
None
1.45A 5hrqC-1mdaH:
undetectable
5hrqD-1mdaH:
undetectable
5hrqL-1mdaH:
undetectable
5hrqC-1mdaH:
9.77
5hrqD-1mdaH:
7.69
5hrqL-1mdaH:
7.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5INZ_D_DVAD15_0
(THETA DEFENSIN-2,
D-PEPTIDE
THETA DEFENSIN-2,
L-PEPTIDE)
1mda METHYLAMINE
DEHYDROGENASE (HEAVY
SUBUNIT)

(Paracoccus
denitrificans)
3 / 3 GLY H 181
CYH H 183
CYH H 167
None
0.63A 5inzB-1mdaH:
undetectable
5inzB-1mdaH:
5.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N9X_A_THRA601_0
(ADENYLATION DOMAIN)
1mda METHYLAMINE
DEHYDROGENASE (HEAVY
SUBUNIT)

(Paracoccus
denitrificans)
4 / 7 ASP H 102
PHE H 106
GLY H  26
GLY H  28
None
0.96A 5n9xA-1mdaH:
undetectable
5n9xA-1mdaH:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1471_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)
1mda AMICYANIN
METHYLAMINE
DEHYDROGENASE (LIGHT
SUBUNIT)

(Paracoccus
denitrificans)
5 / 12 ASP L 113
GLY L 111
HIS A  56
ASN A  54
THR A  93
None
1.37A 5x7pB-1mdaL:
0.0
5x7pB-1mdaL:
6.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YN6_A_SAMA401_0
(NSP16 PROTEIN)
1mda METHYLAMINE
DEHYDROGENASE (HEAVY
SUBUNIT)

(Paracoccus
denitrificans)
5 / 12 GLY H 236
PRO H 222
LEU H 234
ASP H 237
MET H 245
None
1.28A 5yn6A-1mdaH:
0.0
5yn6A-1mdaH:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNI_A_SAMA401_0
(NSP16 PROTEIN)
1mda METHYLAMINE
DEHYDROGENASE (HEAVY
SUBUNIT)

(Paracoccus
denitrificans)
5 / 12 GLY H 236
PRO H 222
LEU H 234
ASP H 237
MET H 245
None
1.28A 5yniA-1mdaH:
undetectable
5yniA-1mdaH:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNM_A_SAMA401_0
(NSP16 PROTEIN)
1mda METHYLAMINE
DEHYDROGENASE (HEAVY
SUBUNIT)

(Paracoccus
denitrificans)
5 / 12 GLY H 236
PRO H 222
LEU H 234
ASP H 237
MET H 245
None
1.30A 5ynmA-1mdaH:
undetectable
5ynmA-1mdaH:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1mda METHYLAMINE
DEHYDROGENASE (HEAVY
SUBUNIT)

(Paracoccus
denitrificans)
3 / 3 ARG H 119
PHE H 143
PHE H  66
None
0.82A 6nknC-1mdaH:
undetectable
6nknJ-1mdaH:
0.0
6nknC-1mdaH:
19.30
6nknJ-1mdaH:
10.44