SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mdm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_F_ACTF402_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 1mdm C-ETS-1 PROTEIN
(Mus
musculus) 		3 / 3 PHE B 363
ASP B 359
ARG B 413
 None
 0.52A 4eahF-1mdmB:
undetectable		 4eahF-1mdmB:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_G_ACTG401_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 1mdm C-ETS-1 PROTEIN
(Mus
musculus) 		3 / 3 PHE B 363
ASP B 359
ARG B 413
 None
 0.52A 4eahG-1mdmB:
undetectable		 4eahG-1mdmB:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_E_CHDE104_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1mdm C-ETS-1 PROTEIN
(Mus
musculus) 		6 / 11 GLU B 343
ALA B 325
LEU B 326
TYR B 329
LEU B 422
LEU B 421
 None
 1.50A 4wg0C-1mdmB:
undetectable
4wg0D-1mdmB:
undetectable
4wg0E-1mdmB:
undetectable		 4wg0C-1mdmB:
7.05
4wg0D-1mdmB:
7.05
4wg0E-1mdmB:
7.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_1
(SCRFP-TAG,GP41)		 1mdm C-ETS-1 PROTEIN
(Mus
musculus) 		5 / 12 GLY B 376
GLN B 339
LEU B 341
GLU B 343
LEU B 344
 None
 0.88A 5nwwA-1mdmB:
0.0		 5nwwA-1mdmB:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_1
(SCRFP-TAG,GP41)		 1mdm C-ETS-1 PROTEIN
(Mus
musculus) 		5 / 12 GLY B 376
GLN B 339
LEU B 342
GLU B 343
LEU B 344
 None
 1.16A 5nwwA-1mdmB:
0.0		 5nwwA-1mdmB:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_A_8NUA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 1mdm C-ETS-1 PROTEIN
(Mus
musculus) 		5 / 12 LEU B 326
PHE B 414
PHE B 363
LEU B 418
TYR B 396
 None
 1.13A 6a93A-1mdmB:
undetectable		 6a93A-1mdmB:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_D_AM2D301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1mdm C-ETS-1 PROTEIN
(Mus
musculus) 		4 / 8 ARG B 413
HIS B 403
GLU B 362
ASP B 359
 None
 1.02A 6mn4D-1mdmB:
undetectable		 6mn4D-1mdmB:
22.54