SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mdu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD8_0
(GRAMICIDIN A)		 1mdu GELSOLIN PRECURSOR
(Homo
sapiens) 		3 / 3 VAL A  45
VAL A  22
TRP A  20
 None
 0.71A 1av2C-1mduA:
undetectable
1av2D-1mduA:
undetectable		 1av2C-1mduA:
7.87
1av2D-1mduA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_A_SAMA3142_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 1mdu GELSOLIN PRECURSOR
(Homo
sapiens) 		4 / 4 HIS A  62
ASP A  85
ASN A  89
ASP A  60
 None
CA  A 403 (-2.5A)
None
None
 1.25A 1wg8A-1mduA:
undetectable		 1wg8A-1mduA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB8_0
(GRAMICIDIN D)		 1mdu GELSOLIN PRECURSOR
(Homo
sapiens) 		3 / 3 VAL A  45
VAL A  22
TRP A  20
 None
 0.86A 3l8lA-1mduA:
undetectable
3l8lB-1mduA:
undetectable		 3l8lA-1mduA:
7.87
3l8lB-1mduA:
7.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 1mdu GELSOLIN PRECURSOR
(Homo
sapiens) 		4 / 7 TYR A 109
ILE A  46
LEU A 114
GLY A  36
 None
None
None
TRS  A 472 ( 4.7A)
 0.92A 4iqqA-1mduA:
undetectable		 4iqqA-1mduA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 1mdu GELSOLIN PRECURSOR
(Homo
sapiens) 		4 / 7 TYR A 109
ILE A  46
LEU A 114
GLY A  36
 None
None
None
TRS  A 472 ( 4.7A)
 0.83A 4iqqB-1mduA:
undetectable		 4iqqB-1mduA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1mdu GELSOLIN PRECURSOR
(Homo
sapiens) 		4 / 8 TYR A 109
ILE A  46
LEU A 114
GLY A  36
 None
None
None
TRS  A 472 ( 4.7A)
 0.91A 5nooD-1mduA:
undetectable		 5nooD-1mduA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 1mdu GELSOLIN PRECURSOR
(Homo
sapiens) 		4 / 8 GLU A  73
VAL A  22
GLY A  66
THR A  40
 CA  A 402 (-2.3A)
None
None
None
 0.91A 5sxtA-1mduA:
undetectable		 5sxtA-1mduA:
10.64