SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mec'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1mec MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP1)
(Cardiovirus
A) 		4 / 5 TYR 1  37
TYR 1 242
PHE 1 120
PRO 1 119
 None
 1.16A 1dfoB-1mec1:
undetectable		 1dfoB-1mec1:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_B_FFOB2002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1mec MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP1)
(Cardiovirus
A) 		4 / 5 TYR 1  37
TYR 1 242
PHE 1 120
PRO 1 119
 None
 1.16A 1dfoA-1mec1:
undetectable		 1dfoA-1mec1:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1mec MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP1)
(Cardiovirus
A) 		4 / 5 TYR 1  37
TYR 1 242
PHE 1 120
PRO 1 119
 None
 1.16A 1dfoD-1mec1:
undetectable		 1dfoD-1mec1:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_D_FFOD4002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1mec MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP1)
(Cardiovirus
A) 		4 / 5 TYR 1  37
TYR 1 242
PHE 1 120
PRO 1 119
 None
 1.16A 1dfoC-1mec1:
undetectable		 1dfoC-1mec1:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_FFOA505_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1mec MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP1)
(Cardiovirus
A) 		4 / 6 TYR 1  37
TYR 1 242
PHE 1 120
PRO 1 119
 None
 1.20A 2vmyA-1mec1:
undetectable		 2vmyA-1mec1:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_0
(REPRESSOR PROTEIN
MPHR(A))		 1mec MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP1)
(Cardiovirus
A) 		5 / 12 THR 1 150
VAL 1 188
LEU 1 240
VAL 1 129
ILE 1  43
 None
 1.28A 3frqA-1mec1:
undetectable		 3frqA-1mec1:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCP_B_CHDB4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1mec MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP1)
(Cardiovirus
A) 		3 / 3 GLY 1  56
PRO 1 154
LEU 1 165
 None
 0.58A 3hcpB-1mec1:
undetectable		 3hcpB-1mec1:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1mec MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP1)
(Cardiovirus
A) 		5 / 8 VAL 1  69
LEU 1 225
ILE 1  43
VAL 1 238
LEU 1 131
 None
 1.17A 3kp6A-1mec1:
undetectable
3kp6B-1mec1:
undetectable		 3kp6A-1mec1:
18.61
3kp6B-1mec1:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG801_0
(GLUTAMATE RECEPTOR 2)		 1mec MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP1)
(Cardiovirus
A) 		3 / 3 PRO 1 232
SER 1  50
ASN 1  62
 None
 0.90A 3lslG-1mec1:
undetectable		 3lslG-1mec1:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_I_ACHI323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 1mec MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP1)
(Cardiovirus
A) 		4 / 8 PHE 1 222
ILE 1  43
TYR 1 242
PHE 1 114
 None
 0.96A 3rqwI-1mec1:
undetectable
3rqwJ-1mec1:
0.0		 3rqwI-1mec1:
21.78
3rqwJ-1mec1:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1mec MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP1)
(Cardiovirus
A) 		3 / 3 SER 1  55
GLY 1  56
GLN 1 157
 None
 0.63A 3v4tH-1mec1:
0.0		 3v4tH-1mec1:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LJ0_A_ACTA505_0
(NAB2)		 1mec MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP1)
(Cardiovirus
A) 		3 / 3 LEU 1 106
LYS 1 107
THR 1 108
 None
 0.55A 4lj0A-1mec1:
undetectable		 4lj0A-1mec1:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD4_C_AOQC4003_1
(CYTOCHROME B)		 1mec MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP1)
(Cardiovirus
A) 		5 / 12 GLY 1  44
VAL 1 238
ILE 1  43
PRO 1  66
LEU 1 225
 None
 1.09A 4pd4C-1mec1:
undetectable		 4pd4C-1mec1:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K4P_A_SORA611_0
(PROBABLE
PHOSPHATIDYLETHANOLA
MINE TRANSFERASE
MCR-1)		 1mec MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP1)
(Cardiovirus
A) 		4 / 6 GLY 1 149
THR 1 148
GLY 1 223
ASN 1 219
 None
 0.89A 5k4pA-1mec1:
undetectable		 5k4pA-1mec1:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA504_1
(-)		 1mec MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP1)
(Cardiovirus
A) 		4 / 8 ILE 1 234
VAL 1  48
ALA 1 176
LEU 1 141
 None
 0.48A 5og9A-1mec1:
undetectable		 5og9A-1mec1:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_A_BEZA301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 1mec MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP1)
(Cardiovirus
A) 		4 / 7 SER 1 192
LEU 1 194
LEU 1 197
PRO 1 218
 None
 1.01A 5u4sA-1mec1:
undetectable		 5u4sA-1mec1:
17.75