SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mex'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1mex FAB 29G12 HEAVY
CHAIN
(Mus
musculus) 		4 / 7 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.76A 1usqA-1mexH:
2.1		 1usqA-1mexH:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1mex FAB 29G12 HEAVY
CHAIN
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.77A 1usqB-1mexH:
undetectable		 1usqB-1mexH:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1mex FAB 29G12 HEAVY
CHAIN
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.76A 1usqC-1mexH:
2.2		 1usqC-1mexH:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1mex FAB 29G12 HEAVY
CHAIN
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.77A 1usqD-1mexH:
2.1		 1usqD-1mexH:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1mex FAB 29G12 HEAVY
CHAIN
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.78A 1usqE-1mexH:
undetectable		 1usqE-1mexH:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1mex FAB 29G12 HEAVY
CHAIN
(Mus
musculus) 		4 / 7 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.76A 1usqF-1mexH:
undetectable		 1usqF-1mexH:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_A_CLMA1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1mex FAB 29G12 HEAVY
CHAIN
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.82A 2jkjA-1mexH:
2.2		 2jkjA-1mexH:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_B_CLMB1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1mex FAB 29G12 HEAVY
CHAIN
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.82A 2jkjB-1mexH:
undetectable		 2jkjB-1mexH:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_C_CLMC1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1mex FAB 29G12 HEAVY
CHAIN
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.82A 2jkjC-1mexH:
2.1		 2jkjC-1mexH:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_E_CLME1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1mex FAB 29G12 HEAVY
CHAIN
(Mus
musculus) 		4 / 7 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.82A 2jkjE-1mexH:
undetectable		 2jkjE-1mexH:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1mex FAB 29G12 HEAVY
CHAIN
(Mus
musculus) 		4 / 7 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.80A 2jklA-1mexH:
undetectable		 2jklA-1mexH:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1mex FAB 29G12 HEAVY
CHAIN
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.81A 2jklB-1mexH:
2.1		 2jklB-1mexH:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1mex FAB 29G12 HEAVY
CHAIN
(Mus
musculus) 		4 / 7 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.80A 2jklC-1mexH:
undetectable		 2jklC-1mexH:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1mex FAB 29G12 HEAVY
CHAIN
(Mus
musculus) 		4 / 7 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.80A 2jklD-1mexH:
2.1		 2jklD-1mexH:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1mex FAB 29G12 HEAVY
CHAIN
(Mus
musculus) 		4 / 7 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.81A 2jklE-1mexH:
undetectable		 2jklE-1mexH:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1mex FAB 29G12 HEAVY
CHAIN
(Mus
musculus) 		4 / 7 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.81A 2jklF-1mexH:
2.1		 2jklF-1mexH:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNP_A_ROCA401_2
(PROTEASE)		 1mex FAB 29G12 HEAVY
CHAIN
(Mus
musculus) 		5 / 11 LEU H 140
VAL H 171
GLY H 164
VAL H 193
VAL H 191
 None
 1.08A 2nnpB-1mexH:
undetectable		 2nnpB-1mexH:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMM_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1mex FAB 29G12 HEAVY
CHAIN
(Mus
musculus) 		4 / 5 MET H  94
LEU H  97
PRO H  52
SER H  52
 None
 1.43A 4kmmB-1mexH:
undetectable		 4kmmB-1mexH:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1mex FAB 29G12 HEAVY
CHAIN
(Mus
musculus) 		3 / 3 SER H 216
ALA H 211
VAL H 210
 None
 0.58A 5eypA-1mexH:
undetectable		 5eypA-1mexH:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_G_ACTG702_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 1mex FAB 29G12 HEAVY
CHAIN
(Mus
musculus) 		3 / 3 GLY H  65
THR H  68
ASN H  82
 None
 0.63A 5odiG-1mexH:
undetectable		 5odiG-1mexH:
16.87