SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mf1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		4 / 7 GLY A  66
ALA A 134
HIS A 105
THR A 170
 None
 0.86A 1c9sT-1mf1A:
0.0
1c9sU-1mf1A:
0.0		 1c9sT-1mf1A:
12.81
1c9sU-1mf1A:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		5 / 12 LEU A 359
GLY A 296
HIS A 351
ALA A  39
PHE A 432
 None
 1.15A 1dfoA-1mf1A:
undetectable		 1dfoA-1mf1A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_B_FFOB2002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		5 / 12 LEU A 359
GLY A 296
HIS A 351
ALA A  39
PHE A 432
 None
 1.15A 1dfoB-1mf1A:
undetectable		 1dfoB-1mf1A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		5 / 12 LEU A 359
GLY A 296
HIS A 351
ALA A  39
PHE A 432
 None
 1.15A 1dfoC-1mf1A:
undetectable		 1dfoC-1mf1A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_D_FFOD4002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		5 / 12 LEU A 359
GLY A 296
HIS A 351
ALA A  39
PHE A 432
 None
 1.15A 1dfoD-1mf1A:
undetectable		 1dfoD-1mf1A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		4 / 7 GLY A  66
ALA A 134
HIS A 105
THR A 170
 None
 0.90A 1gtfL-1mf1A:
0.0
1gtfM-1mf1A:
0.0		 1gtfL-1mf1A:
12.81
1gtfM-1mf1A:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		4 / 8 GLY A  66
ALA A 134
HIS A 105
THR A 170
 None
 0.88A 1gtfN-1mf1A:
undetectable
1gtfO-1mf1A:
0.0		 1gtfN-1mf1A:
12.81
1gtfO-1mf1A:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_A_VIBA502_1
(THIAMIN
PYROPHOSPHOKINASE)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		4 / 8 LEU A 456
SER A 452
ASP A 421
THR A 414
 None
 1.08A 1ig3A-1mf1A:
0.0
1ig3B-1mf1A:
0.0		 1ig3A-1mf1A:
20.93
1ig3B-1mf1A:
20.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MF1_A_ACTA458_0
(ADENYLOSUCCINATE
SYNTHETASE)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		4 / 4 GLY A  45
LYS A  46
GLY A  47
HIS A  71
 ACT  A 458 (-3.5A)
ACT  A 458 (-3.0A)
ACT  A 458 (-3.6A)
ACT  A 458 (-4.0A)
 0.03A 1mf1A-1mf1A:
72.2		 1mf1A-1mf1A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA140_0
(LYSOZYME C)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		3 / 3 ASN A  67
ALA A  69
ASN A 256
 None
None
AMP  A 459 (-3.9A)
 0.78A 1n4fA-1mf1A:
undetectable		 1n4fA-1mf1A:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_A_ACTA1107_0
(C5A PEPTIDASE)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		4 / 5 LEU A 109
GLY A 108
HIS A 105
ILE A 104
 None
 0.98A 1xf1A-1mf1A:
undetectable		 1xf1A-1mf1A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_0
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		5 / 12 ILE A  98
GLY A 283
GLY A  66
ALA A 134
HIS A 135
 None
 0.86A 2fk8A-1mf1A:
undetectable		 2fk8A-1mf1A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_J_TACJ5888_1
(ELONGATION FACTOR
EF-TU)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		4 / 6 THR A 414
SER A 452
SER A 449
VAL A  74
 None
 1.30A 2hdnI-1mf1A:
0.0
2hdnJ-1mf1A:
2.6
2hdnL-1mf1A:
2.3		 2hdnI-1mf1A:
6.43
2hdnJ-1mf1A:
22.32
2hdnL-1mf1A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_2
(PROTEASE)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		5 / 12 LEU A 406
ASP A 368
ILE A 366
VAL A 375
ILE A 373
 None
 0.85A 2o4lB-1mf1A:
undetectable		 2o4lB-1mf1A:
11.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		4 / 8 ARG A 431
ASP A 343
LEU A 344
GLY A 376
 None
 0.94A 2tsrB-1mf1A:
undetectable		 2tsrB-1mf1A:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_2
(PROTEASE)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		5 / 9 ASP A 132
GLY A  99
LEU A 284
VAL A  95
ILE A 129
 None
 1.21A 3em4B-1mf1A:
undetectable		 3em4B-1mf1A:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_B_H3PB552_1
(GLUTAMATE
DEHYDROGENASE)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		3 / 3 TYR A 301
TYR A 429
ILE A 373
 None
 0.77A 3eteA-1mf1A:
undetectable
3eteB-1mf1A:
undetectable		 3eteA-1mf1A:
21.45
3eteB-1mf1A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_A_C2FA314_0
(UNCHARACTERIZED
PROTEIN)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		5 / 12 LEU A 109
VAL A 102
GLY A  65
LEU A  85
ILE A  89
 None
 1.11A 3ijdA-1mf1A:
undetectable		 3ijdA-1mf1A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		4 / 6 VAL A  50
SER A  96
LEU A 243
ILE A 129
 None
 0.99A 3kk6A-1mf1A:
undetectable		 3kk6A-1mf1A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_2
(HIV-1 PROTEASE)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		5 / 11 LEU A 406
ASP A 368
ILE A 366
VAL A 375
ILE A 373
 None
 0.91A 3oxxD-1mf1A:
undetectable		 3oxxD-1mf1A:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ6_A_SAMA300_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		5 / 12 LEU A 128
ILE A  59
GLY A  99
ILE A 130
LEU A  84
 None
 0.91A 3uj6A-1mf1A:
undetectable		 3uj6A-1mf1A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		5 / 12 LEU A 128
ILE A  59
GLY A  99
ILE A 130
LEU A  84
 None
 0.90A 3uj7B-1mf1A:
undetectable		 3uj7B-1mf1A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_1
(HIV-1 PROTEASE)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		5 / 12 LEU A 406
ASP A 368
ILE A 366
VAL A 375
ILE A 373
 None
 0.83A 4jecA-1mf1A:
undetectable		 4jecA-1mf1A:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE502_0
(RNA POLYMERASE
3D-POL)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		3 / 3 ARG A 385
LYS A 384
LYS A 380
 None
 1.40A 4k50E-1mf1A:
0.0		 4k50E-1mf1A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI506_0
(RNA POLYMERASE
3D-POL)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		3 / 3 ARG A 385
LYS A 384
LYS A 380
 None
 1.42A 4k50I-1mf1A:
0.0		 4k50I-1mf1A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_A_SAMA301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		5 / 12 TRP A 341
GLY A 376
LEU A 347
LEU A 344
GLU A  44
 None
 1.08A 4lg1A-1mf1A:
2.2		 4lg1A-1mf1A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_B_SAMB301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		5 / 12 TRP A 341
GLY A 376
LEU A 347
LEU A 344
GLU A  44
 None
 1.09A 4lg1B-1mf1A:
undetectable		 4lg1B-1mf1A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_B_SAMB301_0
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		5 / 12 LEU A 284
GLY A 254
ASN A 354
ALA A 255
ASN A 256
 None
None
None
None
AMP  A 459 (-3.9A)
 1.37A 4pclB-1mf1A:
2.7		 4pclB-1mf1A:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		5 / 12 GLY A  65
HIS A 135
GLY A  99
ILE A  98
GLY A 278
 None
 0.96A 5d4uC-1mf1A:
undetectable		 5d4uC-1mf1A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		5 / 12 GLY A  65
HIS A 135
GLY A  99
ILE A  98
GLY A 278
 None
 0.97A 5d4uD-1mf1A:
undetectable		 5d4uD-1mf1A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		4 / 8 THR A 170
GLY A  66
ALA A 134
HIS A 105
 None
 0.90A 5eevL-1mf1A:
undetectable
5eevV-1mf1A:
undetectable		 5eevL-1mf1A:
12.81
5eevV-1mf1A:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		4 / 8 THR A 170
GLY A  66
ALA A 134
HIS A 105
 None
 0.90A 5eewL-1mf1A:
undetectable
5eewV-1mf1A:
undetectable		 5eewL-1mf1A:
12.81
5eewV-1mf1A:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		4 / 8 THR A 170
GLY A  66
ALA A 134
HIS A 105
 None
 0.90A 5ef3L-1mf1A:
undetectable
5ef3V-1mf1A:
undetectable		 5ef3L-1mf1A:
12.81
5ef3V-1mf1A:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_A_MMZA503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		3 / 3 ASN A 256
SER A 273
SER A 272
 AMP  A 459 (-3.9A)
None
None
 0.75A 5gsnA-1mf1A:
undetectable		 5gsnA-1mf1A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KXI_A_NCTA402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		4 / 8 TYR A 429
THR A 362
TYR A 301
TRP A 409
 None
 1.48A 5kxiA-1mf1A:
0.0
5kxiB-1mf1A:
0.0		 5kxiA-1mf1A:
21.83
5kxiB-1mf1A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KXI_D_NCTD402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		4 / 8 TYR A 429
THR A 362
TYR A 301
TRP A 409
 None
 1.46A 5kxiD-1mf1A:
0.0
5kxiE-1mf1A:
0.0		 5kxiD-1mf1A:
21.83
5kxiE-1mf1A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0I_B_ACTB303_0
(SWI5-DEPENDENT HO
EXPRESSION PROTEIN 2)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		4 / 5 VAL A 353
THR A 276
ASN A 274
ASP A 263
 None
 1.17A 5m0iB-1mf1A:
undetectable		 5m0iB-1mf1A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_F_CCSF14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		4 / 6 LEU A 251
SER A  96
ARG A 127
GLY A  88
 None
 1.05A 5o4yF-1mf1A:
undetectable		 5o4yF-1mf1A:
2.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW9_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		4 / 8 SER A 131
GLY A 101
ALA A 134
GLY A 283
 None
 0.63A 5vw9A-1mf1A:
undetectable		 5vw9A-1mf1A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WEA_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		4 / 5 LEU A 367
LYS A 363
LEU A 322
GLU A 328
 None
 1.26A 5weaA-1mf1A:
undetectable		 5weaA-1mf1A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_I_PACI1_0
(SERINE PROTEASE NS3
SERINE PROTEASE
SUBUNIT NS2B
PEPTIDE
PAC-DLY-DLY-DAR)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		3 / 3 VAL A  73
TYR A  80
GLU A 253
 None
 0.74A 5zmqD-1mf1A:
undetectable
5zmqE-1mf1A:
undetectable		 5zmqD-1mf1A:
20.45
5zmqE-1mf1A:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNJ_D_NCTD402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 1mf1 ADENYLOSUCCINATE
SYNTHETASE
(Mus
musculus) 		4 / 8 TYR A 429
THR A 362
TYR A 301
TRP A 409
 None
 1.28A 6cnjD-1mf1A:
undetectable
6cnjE-1mf1A:
undetectable		 6cnjD-1mf1A:
11.82
6cnjE-1mf1A:
11.28