SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mfq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A27_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)		 1mfq SIGNAL RECOGNITION
PARTICLE 54KDA
PROTEIN
(Homo
sapiens) 		5 / 12 VAL C 395
GLY C 392
LEU C 421
TYR C 424
VAL C 406
 None
 1.41A 1a27A-1mfqC:
undetectable		 1a27A-1mfqC:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA502_0
(CHORISMATE SYNTHASE)		 1mfq SIGNAL RECOGNITION
PARTICLE 54KDA
PROTEIN
(Homo
sapiens) 		3 / 3 GLY C 392
ASP C 391
SER C 389
 None
 0.74A 2qhfA-1mfqC:
undetectable		 2qhfA-1mfqC:
13.94