SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mg1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB8_0
(GRAMICIDIN A)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		3 / 3 TRP A 159
VAL A 260
TRP A 341
 None
None
MAL  A 456 (-3.9A)
 1.13A 1c4dA-1mg1A:
undetectable
1c4dB-1mg1A:
undetectable		 1c4dA-1mg1A:
2.78
1c4dB-1mg1A:
2.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_A_IPBA600_0
(ODORANT-BINDING
PROTEIN)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		4 / 6 VAL A   9
VAL A  51
ILE A  61
ASN A 268
 None
 0.93A 1e06A-1mg1A:
0.0		 1e06A-1mg1A:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		3 / 3 THR A 246
LEU A 116
LEU A 161
 None
 0.64A 1mz9C-1mg1A:
3.5		 1mz9C-1mg1A:
7.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_1
(RETINOIC ACID
RECEPTOR, BETA)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		5 / 12 LEU A 196
LEU A 199
ILE A 200
LEU A 152
LEU A 161
 None
 1.00A 1xdkF-1mg1A:
0.0		 1xdkF-1mg1A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		4 / 8 ILE A  60
PHE A  62
THR A 287
LEU A 286
 None
 0.93A 2einA-1mg1A:
undetectable
2einJ-1mg1A:
2.3		 2einA-1mg1A:
20.70
2einJ-1mg1A:
7.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_A_SAMA500_0
(HYPOTHETICAL PROTEIN)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		4 / 7 VAL A  98
ALA A 106
PHE A  93
PRO A  92
 None
 1.03A 2q6oA-1mg1A:
undetectable		 2q6oA-1mg1A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		4 / 6 ALA A 189
LEU A 193
ALA A 347
THR A 346
 None
 0.88A 3b6hA-1mg1A:
undetectable		 3b6hA-1mg1A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		4 / 6 ALA A 189
LEU A 193
ALA A 347
THR A 346
 None
 0.92A 3b6hB-1mg1A:
undetectable		 3b6hB-1mg1A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJ8_C_SPMC500_1
(DIAMINE
ACETYLTRANSFERASE 1)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		4 / 6 ASP A  15
LEU A  44
LEU A  21
TRP A  63
 MAL  A 456 (-3.4A)
None
None
MAL  A 456 (-4.3A)
 1.25A 3bj8C-1mg1A:
0.0
3bj8D-1mg1A:
0.0		 3bj8C-1mg1A:
15.71
3bj8D-1mg1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_1
(PHOSPHOLIPASE A2)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		4 / 7 VAL A 111
GLY A 301
PRO A 230
LYS A 306
 None
 0.77A 3bjwC-1mg1A:
undetectable		 3bjwC-1mg1A:
13.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		9 / 12 ASP A  15
LYS A  16
GLU A  45
GLU A  46
ALA A  64
ASP A  66
GLU A 112
PRO A 155
TRP A 231
 MAL  A 456 (-3.4A)
MAL  A 456 (-2.8A)
None
None
MAL  A 456 (-3.1A)
MAL  A 456 (-2.8A)
MAL  A 456 (-2.6A)
MAL  A 456 (-3.5A)
MAL  A 456 ( 4.8A)
 0.60A 3jyrA-1mg1A:
59.7		 3jyrA-1mg1A:
79.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		6 / 7 ASN A  13
TRP A  63
GLU A 154
TYR A 156
MET A 331
TRP A 341
 MAL  A 456 (-4.4A)
MAL  A 456 (-4.3A)
MAL  A 456 (-4.0A)
MAL  A 456 (-3.8A)
MAL  A 456 ( 4.2A)
MAL  A 456 (-3.9A)
 0.33A 3jyrA-1mg1A:
59.7		 3jyrA-1mg1A:
79.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		4 / 7 TYR A 156
MET A 331
TRP A 341
ARG A 345
 MAL  A 456 (-3.8A)
MAL  A 456 ( 4.2A)
MAL  A 456 (-3.9A)
None
 0.83A 3jyrA-1mg1A:
59.7		 3jyrA-1mg1A:
79.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		5 / 11 GLN A 366
ALA A 365
ALA A 163
GLY A 167
ALA A 189
 None
 1.10A 3mg0V-1mg1A:
undetectable
3mg0W-1mg1A:
undetectable		 3mg0V-1mg1A:
19.07
3mg0W-1mg1A:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_B_DIFB585_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		5 / 12 VAL A 197
LEU A 161
GLY A 188
ALA A 189
LEU A 362
 None
 1.01A 3n8yB-1mg1A:
0.0		 3n8yB-1mg1A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		5 / 12 PHE A 157
GLY A 301
LEU A 300
GLU A 112
ALA A 232
 None
None
None
MAL  A 456 (-2.6A)
None
 0.89A 3tbgB-1mg1A:
0.0		 3tbgB-1mg1A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		5 / 12 PHE A 157
GLY A 301
LEU A 300
GLU A 112
ALA A 232
 None
None
None
MAL  A 456 (-2.6A)
None
 0.87A 3tbgD-1mg1A:
0.0		 3tbgD-1mg1A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VWQ_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		5 / 12 ALA A 232
TYR A  18
TYR A 211
ASN A 235
GLY A 229
 None
 1.38A 3vwqA-1mg1A:
0.0		 3vwqA-1mg1A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		4 / 5 ASN A 268
ALA A  52
GLY A  57
ASP A  15
 None
None
None
MAL  A 456 (-3.4A)
 0.98A 4n48A-1mg1A:
undetectable		 4n48A-1mg1A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		4 / 7 ILE A  60
PHE A  62
THR A 287
LEU A 286
 None
 0.92A 5b1bN-1mg1A:
0.0
5b1bW-1mg1A:
2.3		 5b1bN-1mg1A:
20.70
5b1bW-1mg1A:
7.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		4 / 8 VAL A 344
GLY A 192
LEU A 196
THR A 194
 None
 0.94A 5sxqA-1mg1A:
undetectable		 5sxqA-1mg1A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_B_NIZB808_1
(CATALASE-PEROXIDASE)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		4 / 8 VAL A 344
GLY A 192
LEU A 196
THR A 194
 None
 0.97A 5sxqB-1mg1A:
0.0		 5sxqB-1mg1A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		4 / 8 VAL A 344
GLY A 192
LEU A 196
THR A 194
 None
 0.94A 5sxtA-1mg1A:
undetectable		 5sxtA-1mg1A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_B_NIZB808_1
(CATALASE-PEROXIDASE)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		4 / 8 VAL A 344
GLY A 192
LEU A 196
THR A 194
 None
 0.95A 5sxtB-1mg1A:
undetectable		 5sxtB-1mg1A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB809_1
(CATALASE-PEROXIDASE)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		4 / 8 VAL A 344
GLY A 192
LEU A 196
THR A 194
 None
 0.97A 5syjB-1mg1A:
0.0		 5syjB-1mg1A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_1
(RIBOFLAVIN LYASE)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		6 / 12 ALA A 343
ALA A 339
GLY A 167
ALA A 189
PHE A 170
VAL A 182
 None
 1.38A 5w4zA-1mg1A:
0.2		 5w4zA-1mg1A:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_B_RBFB502_1
(RIBOFLAVIN LYASE)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		6 / 12 ALA A 343
ALA A 339
GLY A 167
ALA A 189
PHE A 170
VAL A 182
 None
 1.41A 5w4zB-1mg1A:
undetectable		 5w4zB-1mg1A:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_H_BO2H301_0
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		5 / 12 GLN A 366
ALA A 365
ALA A 163
GLY A 167
ALA A 189
 None
 1.00A 6hwdH-1mg1A:
undetectable
6hwdI-1mg1A:
undetectable		 6hwdH-1mg1A:
11.30
6hwdI-1mg1A:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_V_BO2V301_0
(PROTEASOME SUBUNIT
BETA TYPE-2)		 1mg1 PROTEIN (HTLV-1 GP21
ECTODOMAIN/MALTOSE-B
INDING PROTEIN
CHIMERA)
(Primate
T-lymphotropic
virus
1) 		5 / 11 GLN A 366
ALA A 365
ALA A 163
GLY A 167
ALA A 189
 None
 1.00A 6hwdV-1mg1A:
undetectable		 6hwdV-1mg1A:
11.30