SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mg7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWH_A_PEMA501_1
(HEMOGLOBIN ALPHA
CHAIN)		 1mg7 EARLY SWITCH PROTEIN
XOL-1 2.2K SPLICE
FORM
(Caenorhabditis
elegans) 		4 / 6 ALA A 236
LYS A 239
ASP A 243
ALA A 244
 None
 0.45A 1iwhA-1mg7A:
0.0		 1iwhA-1mg7A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA156_1
(CALMODULIN)		 1mg7 EARLY SWITCH PROTEIN
XOL-1 2.2K SPLICE
FORM
(Caenorhabditis
elegans) 		5 / 8 ILE A  88
LEU A 104
MET A 136
VAL A  70
ILE A 119
 None
 1.45A 1linA-1mg7A:
undetectable		 1linA-1mg7A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1mg7 EARLY SWITCH PROTEIN
XOL-1 2.2K SPLICE
FORM
(Caenorhabditis
elegans) 		3 / 3 THR A 100
LEU A 104
LEU A 111
 None
 0.59A 1mz9C-1mg7A:
undetectable		 1mz9C-1mg7A:
8.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z35_A_2FAA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1mg7 EARLY SWITCH PROTEIN
XOL-1 2.2K SPLICE
FORM
(Caenorhabditis
elegans) 		5 / 10 MET A 231
GLY A 308
VAL A 304
GLU A 282
SER A 128
 None
 1.37A 1z35A-1mg7A:
undetectable		 1z35A-1mg7A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_2
(ANDROGEN RECEPTOR)		 1mg7 EARLY SWITCH PROTEIN
XOL-1 2.2K SPLICE
FORM
(Caenorhabditis
elegans) 		4 / 6 LEU A 349
MET A 263
MET A  57
LEU A 310
 None
 1.33A 2oz7A-1mg7A:
0.5		 2oz7A-1mg7A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA207_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 1mg7 EARLY SWITCH PROTEIN
XOL-1 2.2K SPLICE
FORM
(Caenorhabditis
elegans) 		5 / 12 PHE A 121
PRO A 124
ALA A 132
MET A 136
LEU A 183
 None
 1.08A 4oaeA-1mg7A:
undetectable		 4oaeA-1mg7A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_A_DGXA1107_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1mg7 EARLY SWITCH PROTEIN
XOL-1 2.2K SPLICE
FORM
(Caenorhabditis
elegans) 		5 / 12 LEU A 292
LEU A 347
PHE A 318
GLU A 295
LEU A 372
 None
 1.07A 4retA-1mg7A:
undetectable		 4retA-1mg7A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJE_A_TOYA202_1
(AADB)		 1mg7 EARLY SWITCH PROTEIN
XOL-1 2.2K SPLICE
FORM
(Caenorhabditis
elegans) 		4 / 8 ASP A  90
ASP A  89
GLU A 118
ILE A  75
 None
 0.98A 4xjeA-1mg7A:
undetectable		 4xjeA-1mg7A:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP9_C_1WEC706_1
(TRANSPORTER)		 1mg7 EARLY SWITCH PROTEIN
XOL-1 2.2K SPLICE
FORM
(Caenorhabditis
elegans) 		4 / 4 PHE A 217
ASP A 126
GLY A 307
SER A 127
 None
 1.45A 4xp9C-1mg7A:
undetectable		 4xp9C-1mg7A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP9_C_1WEC706_1
(TRANSPORTER)		 1mg7 EARLY SWITCH PROTEIN
XOL-1 2.2K SPLICE
FORM
(Caenorhabditis
elegans) 		4 / 4 PHE A 217
ASP A 126
GLY A 308
SER A 127
 None
 1.41A 4xp9C-1mg7A:
undetectable		 4xp9C-1mg7A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 1mg7 EARLY SWITCH PROTEIN
XOL-1 2.2K SPLICE
FORM
(Caenorhabditis
elegans) 		4 / 5 ARG A  66
GLN A  67
PRO A  51
ILE A  64
 None
 1.24A 4z4hA-1mg7A:
1.2		 4z4hA-1mg7A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CFS_A_TOYA203_1
(AAD(2''),GENTAMICIN
2''-NUCLEOTIDYLTRANS
FERASE,GENTAMICIN
RESISTANCE PROTEIN)		 1mg7 EARLY SWITCH PROTEIN
XOL-1 2.2K SPLICE
FORM
(Caenorhabditis
elegans) 		4 / 8 ASP A  90
ASP A  89
GLU A 118
ILE A  75
 None
 0.90A 5cfsA-1mg7A:
0.0		 5cfsA-1mg7A:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KI6_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 1mg7 EARLY SWITCH PROTEIN
XOL-1 2.2K SPLICE
FORM
(Caenorhabditis
elegans) 		4 / 5 ARG A  66
GLN A  67
PRO A  51
ILE A  64
 None
 1.28A 5ki6A-1mg7A:
1.4		 5ki6A-1mg7A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L94_A_TESA502_1
(CYTOCHROME P450)		 1mg7 EARLY SWITCH PROTEIN
XOL-1 2.2K SPLICE
FORM
(Caenorhabditis
elegans) 		5 / 8 VAL A 339
ALA A 330
THR A 333
VAL A  17
VAL A 376
 None
 1.32A 5l94A-1mg7A:
undetectable		 5l94A-1mg7A:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L94_A_TESA502_1
(CYTOCHROME P450)		 1mg7 EARLY SWITCH PROTEIN
XOL-1 2.2K SPLICE
FORM
(Caenorhabditis
elegans) 		5 / 8 VAL A 339
ILE A 331
ALA A 330
VAL A  17
VAL A 376
 None
 1.25A 5l94A-1mg7A:
undetectable		 5l94A-1mg7A:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_0
(REGULATORY PROTEIN
TETR)		 1mg7 EARLY SWITCH PROTEIN
XOL-1 2.2K SPLICE
FORM
(Caenorhabditis
elegans) 		5 / 12 ALA A 181
GLY A 185
SER A 186
GLU A 188
LEU A 349
 None
 1.30A 5vlmF-1mg7A:
0.6		 5vlmF-1mg7A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA816_0
(UNCHARACTERIZED
PROTEIN)		 1mg7 EARLY SWITCH PROTEIN
XOL-1 2.2K SPLICE
FORM
(Caenorhabditis
elegans) 		3 / 3 ARG A  66
ARG A 369
ASP A 345
 None
 0.97A 6d8pA-1mg7A:
0.0		 6d8pA-1mg7A:
18.72