SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mh6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 1mh6 BLEOMYCIN RESISTANCE
PROTEIN
(Klebsiella
pneumoniae) 		4 / 8 PHE A 220
GLY A 287
THR A 284
ILE A 281
 None
 0.82A 2a1mB-1mh6A:
undetectable		 2a1mB-1mh6A:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_B_SAMB201_1
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 1mh6 BLEOMYCIN RESISTANCE
PROTEIN
(Klebsiella
pneumoniae) 		4 / 5 ALA A 218
ASP A 310
ASP A 254
ASP A 213
 None
 1.20A 2nyuB-1mh6A:
undetectable		 2nyuB-1mh6A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P6G_A_IZPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 1mh6 BLEOMYCIN RESISTANCE
PROTEIN
(Klebsiella
pneumoniae) 		5 / 12 PHE A 272
ILE A 281
ARG A 223
VAL A 279
CYH A 276
 None
 1.47A 3p6gA-1mh6A:
undetectable		 3p6gA-1mh6A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_A_1N1A601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 1mh6 BLEOMYCIN RESISTANCE
PROTEIN
(Klebsiella
pneumoniae) 		3 / 3 MET A 236
ASP A 310
PHE A 260
 None
 0.90A 4xeyA-1mh6A:
0.1		 4xeyA-1mh6A:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_B_1N1B601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 1mh6 BLEOMYCIN RESISTANCE
PROTEIN
(Klebsiella
pneumoniae) 		3 / 3 MET A 236
ASP A 310
PHE A 260
 None
 0.95A 4xeyB-1mh6A:
0.2		 4xeyB-1mh6A:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_2
(CYP51 VARIANT1)		 1mh6 BLEOMYCIN RESISTANCE
PROTEIN
(Klebsiella
pneumoniae) 		3 / 3 PRO A 309
LEU A 245
SER A 216
 None
 0.73A 5fsaB-1mh6A:
undetectable		 5fsaB-1mh6A:
13.42