SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mhm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AJ6_A_NOVA1_1
(GYRASE)		 1mhm S-ADENOSYLMETHIONINE
DECARBOXYLASE
(Solanum
tuberosum) 		5 / 9 GLU B  20
ASP A 112
ARG B  18
ALA A  95
ILE A  99
 None
 1.49A 1aj6A-1mhmB:
undetectable		 1aj6A-1mhmB:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4007_1
(SERUM ALBUMIN)		 1mhm S-ADENOSYLMETHIONINE
DECARBOXYLASE
(Solanum
tuberosum) 		4 / 8 LEU B  70
ASP B  46
LEU B  45
LEU B  49
 PYR  A  73 ( 4.1A)
None
None
None
 0.94A 1e7cA-1mhmB:
undetectable		 1e7cA-1mhmB:
9.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_2
(GLUCOAMYLASE-471)		 1mhm S-ADENOSYLMETHIONINE
DECARBOXYLASE
(Solanum
tuberosum) 		4 / 6 ALA A  95
SER A  79
ARG B  18
LEU A  92
 None
 1.17A 1gahA-1mhmA:
undetectable		 1gahA-1mhmA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1868_0
(FPRA)		 1mhm S-ADENOSYLMETHIONINE
DECARBOXYLASE
(Solanum
tuberosum) 		3 / 3 ALA A 208
HIS A 209
VAL A 212
 None
 0.36A 1lqtB-1mhmA:
undetectable		 1lqtB-1mhmA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1425_0
(FPRA)		 1mhm S-ADENOSYLMETHIONINE
DECARBOXYLASE
(Solanum
tuberosum) 		3 / 3 ALA A 208
HIS A 209
VAL A 212
 None
 0.36A 1lquB-1mhmA:
undetectable		 1lquB-1mhmA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MIC_A_DVAA6_0
(GRAMICIDIN A)		 1mhm S-ADENOSYLMETHIONINE
DECARBOXYLASE
(Solanum
tuberosum) 		3 / 3 ALA A 292
VAL A 330
TRP A 318
 None
 0.87A 1micA-1mhmA:
undetectable
1micB-1mhmA:
undetectable		 1micA-1mhmA:
4.53
1micB-1mhmA:
4.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_D_ADND1504_1
(CLASS B ACID
PHOSPHATASE)		 1mhm S-ADENOSYLMETHIONINE
DECARBOXYLASE
(Solanum
tuberosum) 		4 / 8 ASP A 296
LEU A 302
THR A 183
TYR A 182
 None
 1.00A 1rmtD-1mhmA:
undetectable		 1rmtD-1mhmA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 1mhm S-ADENOSYLMETHIONINE
DECARBOXYLASE
(Solanum
tuberosum) 		3 / 3 THR A 251
THR A 257
PRO A 252
 None
 0.85A 1unjF-1mhmA:
undetectable		 1unjF-1mhmA:
4.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 1mhm S-ADENOSYLMETHIONINE
DECARBOXYLASE
(Solanum
tuberosum) 		3 / 3 THR A 257
PRO A 252
THR A 251
 None
 0.87A 1unjR-1mhmA:
undetectable		 1unjR-1mhmA:
4.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 1mhm S-ADENOSYLMETHIONINE
DECARBOXYLASE
(Solanum
tuberosum) 		3 / 3 THR A 251
THR A 257
PRO A 252
 None
 0.85A 1unjX-1mhmA:
undetectable		 1unjX-1mhmA:
4.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 1mhm S-ADENOSYLMETHIONINE
DECARBOXYLASE
(Solanum
tuberosum) 		4 / 6 GLY A 265
PRO A 268
LYS A 269
THR A 270
 None
 1.37A 2m2oB-1mhmA:
undetectable		 2m2oB-1mhmA:
9.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_B_LDPB502_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 1mhm S-ADENOSYLMETHIONINE
DECARBOXYLASE
(Solanum
tuberosum) 		4 / 5 GLN A 332
PHE A 334
PHE A 289
GLY A 274
 None
 1.25A 2qmzA-1mhmA:
undetectable
2qmzB-1mhmA:
undetectable		 2qmzA-1mhmA:
21.05
2qmzB-1mhmA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1mhm S-ADENOSYLMETHIONINE
DECARBOXYLASE
(Solanum
tuberosum) 		4 / 6 ILE A 248
MET A 188
THR A 189
LEU A 191
 None
 1.02A 3ag1N-1mhmA:
0.0
3ag1W-1mhmA:
0.0		 3ag1N-1mhmA:
21.00
3ag1W-1mhmA:
9.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_D_MTXD164_2
(DIHYDROFOLATE
REDUCTASE)		 1mhm S-ADENOSYLMETHIONINE
DECARBOXYLASE
(Solanum
tuberosum) 		3 / 3 ARG A 101
ILE A  82
THR A  86
 None
 0.74A 3ia4D-1mhmA:
0.6		 3ia4D-1mhmA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILT_E_TRUE800_1
(GLUTAMATE RECEPTOR 2)		 1mhm S-ADENOSYLMETHIONINE
DECARBOXYLASE
(Solanum
tuberosum) 		5 / 10 ILE B  56
SER A  74
MET A 237
SER A 236
SER B  67
 None
PYR  A  73 ( 3.9A)
None
PYR  A  73 ( 4.1A)
None
 1.49A 3iltB-1mhmB:
undetectable
3iltE-1mhmB:
undetectable		 3iltB-1mhmB:
17.98
3iltE-1mhmB:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 1mhm S-ADENOSYLMETHIONINE
DECARBOXYLASE
(Solanum
tuberosum) 		5 / 12 ILE A 329
SER A 328
GLY A 327
HIS A 294
THR A 299
 None
 1.23A 3r75A-1mhmA:
undetectable		 3r75A-1mhmA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 1mhm S-ADENOSYLMETHIONINE
DECARBOXYLASE
(Solanum
tuberosum) 		5 / 12 ILE A 329
SER A 328
GLY A 327
HIS A 294
THR A 299
 None
 1.23A 3r75B-1mhmA:
2.2		 3r75B-1mhmA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R76_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 1mhm S-ADENOSYLMETHIONINE
DECARBOXYLASE
(Solanum
tuberosum) 		5 / 11 ILE A 329
SER A 328
GLY A 327
HIS A 294
THR A 299
 None
 1.25A 3r76A-1mhmA:
undetectable		 3r76A-1mhmA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R76_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 1mhm S-ADENOSYLMETHIONINE
DECARBOXYLASE
(Solanum
tuberosum) 		5 / 11 ILE A 329
SER A 328
GLY A 327
HIS A 294
THR A 299
 None
 1.28A 3r76B-1mhmA:
undetectable		 3r76B-1mhmA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_B_SUZB201_1
(TRANSTHYRETIN)		 1mhm S-ADENOSYLMETHIONINE
DECARBOXYLASE
(Solanum
tuberosum) 		4 / 8 SER A 246
LEU A 293
LEU A 184
SER A 263
 None
 0.84A 4ikjA-1mhmA:
undetectable
4ikjB-1mhmA:
undetectable		 4ikjA-1mhmA:
21.98
4ikjB-1mhmA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_B_LOCB502_1
(TUBULIN BETA CHAIN)		 1mhm S-ADENOSYLMETHIONINE
DECARBOXYLASE
(Solanum
tuberosum) 		5 / 12 LEU A 140
LEU B  19
VAL A 110
LYS A  81
ILE A  99
 None
 0.98A 4x1yB-1mhmA:
undetectable		 4x1yB-1mhmA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZOW_A_CLMA500_0
(MULTIDRUG
TRANSPORTER MDFA)		 1mhm S-ADENOSYLMETHIONINE
DECARBOXYLASE
S-ADENOSYLMETHIONINE
DECARBOXYLASE
(Solanum
tuberosum;
Solanum
tuberosum) 		5 / 11 LEU A  75
LEU A 108
LEU B  40
LEU B  45
LEU A 106
 None
 1.04A 4zowA-1mhmA:
undetectable		 4zowA-1mhmA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_2
(SCRFP-TAG,GP41)		 1mhm S-ADENOSYLMETHIONINE
DECARBOXYLASE
(Solanum
tuberosum) 		3 / 3 LYS A 164
TRP A 165
SER A 119
 None
 1.38A 5nwwA-1mhmA:
0.0		 5nwwA-1mhmA:
9.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1mhm S-ADENOSYLMETHIONINE
DECARBOXYLASE
(Solanum
tuberosum) 		3 / 3 LEU A 293
ALA A 292
LEU A 273
 None
 0.48A 5uunB-1mhmA:
undetectable		 5uunB-1mhmA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8F_A_ACTA803_0
(UNCHARACTERIZED
PROTEIN)		 1mhm S-ADENOSYLMETHIONINE
DECARBOXYLASE
(Solanum
tuberosum) 		3 / 3 GLU A 278
LEU A 281
ARG A 336
 None
 0.81A 6d8fA-1mhmA:
undetectable		 6d8fA-1mhmA:
16.80