SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mho'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q7K_A_TESA304_1 (ANDROGEN RECEPTOR)	1mho	S-100 PROTEIN (Bos taurus)	5 / 12	LEU A 35 LEU A 32 MET A 74 VAL A 77 LEU A 10	None	1.43A	2q7kA-1mhoA: undetectable	2q7kA-1mhoA: 16.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CR5_X_PNTX94_0 (PROTEIN S100-B)	1mho	S-100 PROTEIN (Bos taurus)	3 / 3	PHE A 43 CYH A 84 PHE A 88	None	1.01A	3cr5X-1mhoA: 18.4	3cr5X-1mhoA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CR5_X_PNTX95_0 (PROTEIN S100-B)	1mho	S-100 PROTEIN (Bos taurus)	3 / 3	CYH A 84 PHE A 87 PHE A 88	None	0.93A	3cr5X-1mhoA: 18.4	3cr5X-1mhoA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3LK0_D_Z80D92_1 (PROTEIN S100-B)	1mho	S-100 PROTEIN (Bos taurus)	3 / 3	HIS A 42 PHE A 87 PHE A 88	None	0.59A	3lk0D-1mhoA: 18.2	3lk0D-1mhoA: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NWV_A_ACAA18_1 (SCRFP-TAG,GP41)	1mho	S-100 PROTEIN (Bos taurus)	5 / 12	SER A 30 GLU A 39 GLU A 34 LEU A 35 GLU A 31	None None None None CA A 90 (-2.1A)	1.13A	5nwvA-1mhoA: 0.1	5nwvA-1mhoA: 15.85

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2Q7K_A_TESA304_1","ANDROGEN RECEPTOR","1mho","S-100 PROTEIN","Bos taurus",5,"LEU A  35;LEU A  32;MET A  74;VAL A  77;LEU A  10","None","1.43A","2q7kA-1mhoA:undetectable","2q7kA-1mhoA:16.93"],["3CR5_X_PNTX94_0","PROTEIN S100-B","1mho","S-100 PROTEIN","Bos taurus",3,"PHE A  43;CYH A  84;PHE A  88","None","1.01A","3cr5X-1mhoA:18.4","3cr5X-1mhoA:100.00"],["3CR5_X_PNTX95_0","PROTEIN S100-B","1mho","S-100 PROTEIN","Bos taurus",3,"CYH A  84;PHE A  87;PHE A  88","None","0.93A","3cr5X-1mhoA:18.4","3cr5X-1mhoA:100.00"],["3LK0_D_Z80D92_1","PROTEIN S100-B","1mho","S-100 PROTEIN","Bos taurus",3,"HIS A  42;PHE A  87;PHE A  88","None","0.59A","3lk0D-1mhoA:18.2","3lk0D-1mhoA:100.00"],["5NWV_A_ACAA18_1","SCRFP-TAG,GP41","1mho","S-100 PROTEIN","Bos taurus",5,"SER A  30;GLU A  39;GLU A  34;LEU A  35;GLU A  31","None;None;None;None; CA A  90 (-2.1A)","1.13A","5nwvA-1mhoA:0.1","5nwvA-1mhoA:15.85"]]