SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mhs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GEB_A_CAMA418_0
(CYTOCHROME P450-CAM)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		5 / 9 PHE A 685
LEU A 761
VAL A 692
ILE A 293
VAL A 289
 None
 1.35A 1gebA-1mhsA:
0.0		 1gebA-1mhsA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_A_EAAA223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		4 / 8 PHE A 479
GLY A 475
LEU A 513
VAL A 502
 None
 0.87A 1gsfA-1mhsA:
1.5		 1gsfA-1mhsA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_B_EAAB223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		4 / 8 PHE A 479
GLY A 475
LEU A 513
VAL A 502
 None
 0.87A 1gsfB-1mhsA:
1.5		 1gsfB-1mhsA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_C_EAAC223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		4 / 8 PHE A 479
GLY A 475
LEU A 513
VAL A 502
 None
 0.87A 1gsfC-1mhsA:
1.5		 1gsfC-1mhsA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_C_EAAC223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		4 / 8 PHE A 810
LEU A 698
VAL A 693
PHE A 868
 None
 1.02A 1gsfC-1mhsA:
1.5		 1gsfC-1mhsA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_D_EAAD223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		4 / 8 PHE A 479
GLY A 475
LEU A 513
VAL A 502
 None
 0.87A 1gsfD-1mhsA:
1.5		 1gsfD-1mhsA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_D_TFPD207_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		4 / 8 LEU A 702
PHE A 841
PHE A 798
SER A 716
 None
 1.01A 1wrlC-1mhsA:
undetectable
1wrlD-1mhsA:
undetectable		 1wrlC-1mhsA:
7.42
1wrlD-1mhsA:
7.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		5 / 12 SER A 368
GLY A 648
VAL A 665
ALA A 658
ALA A 662
 None
 1.26A 2avdB-1mhsA:
0.6		 2avdB-1mhsA:
14.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_4
(POL POLYPROTEIN)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		3 / 3 ARG A 715
VAL A 723
GLY A 145
 None
 0.45A 2avvE-1mhsA:
undetectable		 2avvE-1mhsA:
8.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_E_GCSE710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		4 / 8 ARG A 414
SER A 441
HIS A   4
ASP A   3
 None
 0.85A 2xadA-1mhsA:
undetectable		 2xadA-1mhsA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_F_GCSF710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		4 / 8 ARG A 414
SER A 441
HIS A   4
ASP A   3
 None
 0.89A 2xadB-1mhsA:
undetectable		 2xadB-1mhsA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_G_GCSG710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		4 / 8 ARG A 414
SER A 441
HIS A   4
ASP A   3
 None
 0.88A 2xadC-1mhsA:
undetectable		 2xadC-1mhsA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_H_GCSH710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		4 / 8 ARG A 414
SER A 441
HIS A   4
ASP A   3
 None
 0.91A 2xadD-1mhsA:
undetectable		 2xadD-1mhsA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_A_J01A500_1
(ORF12)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		5 / 10 VAL A 692
ILE A 696
LEU A 117
LEU A 297
GLY A 294
 None
 1.22A 2xf3A-1mhsA:
undetectable		 2xf3A-1mhsA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZI9_A_CL9A401_2
(DEOXYCYTIDINE KINASE)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		3 / 3 ASP A 423
PHE A 426
LEU A 430
 None
 0.64A 2zi9A-1mhsA:
undetectable		 2zi9A-1mhsA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA3_0
(FERROCHELATASE)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		3 / 3 PRO A 477
LEU A 478
ARG A 911
 None
 0.83A 3aqiA-1mhsA:
undetectable		 3aqiA-1mhsA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB5_0
(FERROCHELATASE)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		3 / 3 PRO A 477
LEU A 478
ARG A 911
 None
 0.84A 3aqiB-1mhsA:
undetectable		 3aqiB-1mhsA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6P_B_TA1B502_1
(TUBULIN BETA CHAIN)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		5 / 12 VAL A 907
ASP A 904
GLU A 903
ARG A 570
LEU A 584
 None
 1.05A 3j6pB-1mhsA:
0.1		 3j6pB-1mhsA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN Q5LES9)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		5 / 12 GLY A 587
GLY A 585
PHE A 607
GLU A 582
ALA A 603
 None
 0.98A 3kkzA-1mhsA:
undetectable		 3kkzA-1mhsA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_B_SAMB302_0
(UNCHARACTERIZED
PROTEIN Q5LES9)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		5 / 12 GLY A 587
GLY A 585
PHE A 607
GLU A 582
ALA A 603
 None
 0.86A 3kkzB-1mhsA:
undetectable		 3kkzB-1mhsA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_B_ACTB901_0
(PYRANOSE 2-OXIDASE)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		4 / 6 SER A 283
PHE A 113
HIS A 112
ASN A 291
 None
 1.28A 3lskB-1mhsA:
0.0		 3lskB-1mhsA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_D_ACTD901_0
(PYRANOSE 2-OXIDASE)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		4 / 6 SER A 283
PHE A 113
HIS A 112
ASN A 291
 None
 1.37A 3lskD-1mhsA:
undetectable		 3lskD-1mhsA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_1
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		4 / 6 GLY A 381
THR A 382
LEU A 383
ASP A 534
 None
 1.00A 3ps9A-1mhsA:
undetectable		 3ps9A-1mhsA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_A_SAMA300_0
(PUTATIVE
METHYLTRANSFERASE)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		5 / 12 GLY A 587
GLY A 585
PHE A 607
GLU A 582
ALA A 603
 None
 0.85A 3t7sA-1mhsA:
undetectable		 3t7sA-1mhsA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_B_SAMB300_0
(PUTATIVE
METHYLTRANSFERASE)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		5 / 12 GLY A 587
GLY A 585
PHE A 607
GLU A 582
ALA A 603
 None
 0.84A 3t7sB-1mhsA:
undetectable		 3t7sB-1mhsA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_D_SAMD300_0
(PUTATIVE
METHYLTRANSFERASE)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		5 / 12 GLY A 587
GLY A 585
PHE A 607
GLU A 582
ALA A 603
 None
 0.83A 3t7sD-1mhsA:
undetectable		 3t7sD-1mhsA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UR0_C_SVRC516_1
(RNA-DEPENDENT RNA
POLYMERASE)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		5 / 9 GLY A 207
ALA A 250
ALA A 236
ARG A 253
LEU A 223
 None
 1.27A 3ur0C-1mhsA:
1.8		 3ur0C-1mhsA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_1
(PROTEASE)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		5 / 9 ASP A 663
ALA A 365
VAL A 360
LEU A 353
ILE A 664
 None
 1.30A 3wsjA-1mhsA:
0.0		 3wsjA-1mhsA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_A_CAMA423_0
(CYTOCHROME P450)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		5 / 12 ILE A 554
GLY A 648
THR A 647
VAL A 372
ILE A 374
 None
 0.98A 4c9oA-1mhsA:
undetectable		 4c9oA-1mhsA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_B_CAMB423_0
(CYTOCHROME P450)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		5 / 12 ILE A 554
GLY A 648
THR A 647
VAL A 372
ILE A 374
 None
 0.99A 4c9oB-1mhsA:
undetectable		 4c9oB-1mhsA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_ACTA860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		4 / 5 GLY A 294
ILE A 296
TRP A 756
VAL A 289
 None
 1.23A 4d33A-1mhsA:
0.0		 4d33A-1mhsA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		4 / 5 GLY A 294
ILE A 296
TRP A 756
VAL A 289
 None
 1.23A 4d33B-1mhsA:
undetectable		 4d33B-1mhsA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_2
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		3 / 3 LYS A 379
THR A 380
ILE A 422
 None
 0.93A 4e0fB-1mhsA:
undetectable		 4e0fB-1mhsA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVR_A_SALA203_1
(3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		4 / 7 ASP A 220
GLU A 255
PRO A  10
GLU A 206
 None
 1.13A 4hvrA-1mhsA:
undetectable		 4hvrA-1mhsA:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L3G_F_ACTF401_0
(METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		3 / 3 ARG A 271
LEU A  52
GLU A  53
 None
 0.68A 4l3gF-1mhsA:
0.0		 4l3gF-1mhsA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		4 / 5 ILE A  16
LEU A 176
ASP A 185
GLU A 190
 None
 1.06A 4nkxB-1mhsA:
0.0		 4nkxB-1mhsA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		4 / 8 ALA A 262
ALA A  67
ALA A 247
ALA A 212
 None
 0.78A 4twdF-1mhsA:
3.9
4twdG-1mhsA:
1.0
4twdH-1mhsA:
2.0
4twdI-1mhsA:
0.0
4twdJ-1mhsA:
0.0		 4twdF-1mhsA:
16.14
4twdG-1mhsA:
16.14
4twdH-1mhsA:
16.14
4twdI-1mhsA:
16.14
4twdJ-1mhsA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_H_TR6H101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		3 / 5 GLY A 594
GLY A 589
GLU A 609
 None
 0.49A 4z2eA-1mhsA:
0.0
4z2eD-1mhsA:
undetectable		 4z2eA-1mhsA:
21.31
4z2eD-1mhsA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNU_A_BEZA319_0
(SHKAI2IB)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		4 / 5 GLN A 826
ILE A 736
ILE A 809
TYR A 738
 None
 1.06A 5dnuA-1mhsA:
undetectable		 5dnuA-1mhsA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNV_A_BEZA304_0
(SHKAI2IB)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		4 / 5 GLN A 826
ILE A 736
ILE A 809
TYR A 738
 None
 1.01A 5dnvA-1mhsA:
undetectable		 5dnvA-1mhsA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I71_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		5 / 12 ILE A 696
GLY A 294
GLY A 757
LEU A 761
GLY A 333
 None
 1.22A 5i71A-1mhsA:
2.6		 5i71A-1mhsA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I75_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		5 / 12 ILE A 696
GLY A 294
GLY A 757
LEU A 761
GLY A 333
 None
 1.24A 5i75A-1mhsA:
0.0		 5i75A-1mhsA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KF8_A_GCSA404_1
(PREDICTED
ACETYLTRANSFERASE)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		4 / 8 ARG A  97
GLY A 199
PRO A 198
ASP A 200
 None
 1.15A 5kf8A-1mhsA:
undetectable		 5kf8A-1mhsA:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_A_GCSA407_1
(PREDICTED
ACETYLTRANSFERASE)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		4 / 8 ARG A  97
GLY A 199
PRO A 198
ASP A 200
 None
 1.08A 5kgpA-1mhsA:
undetectable		 5kgpA-1mhsA:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_B_GCSB405_1
(PREDICTED
ACETYLTRANSFERASE)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		4 / 8 ARG A  97
GLY A 199
PRO A 198
ASP A 200
 None
 1.11A 5kgpB-1mhsA:
undetectable		 5kgpB-1mhsA:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		4 / 5 GLU A 805
SER A 699
ARG A 695
GLY A 333
 None
 1.08A 5kprA-1mhsA:
undetectable		 5kprA-1mhsA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		5 / 11 ALA A 247
GLY A  71
GLY A  70
ALA A  67
ASP A 213
 None
 1.03A 5lf3K-1mhsA:
undetectable
5lf3L-1mhsA:
undetectable		 5lf3K-1mhsA:
12.50
5lf3L-1mhsA:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		5 / 11 ALA A 247
GLY A  71
GLY A  70
ALA A  67
ASP A 213
 None
 1.03A 5lf3Y-1mhsA:
undetectable
5lf3Z-1mhsA:
undetectable		 5lf3Y-1mhsA:
12.50
5lf3Z-1mhsA:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		5 / 12 LEU A 178
VAL A 665
ILE A 649
SER A 654
THR A 647
 None
 1.27A 5tiwB-1mhsA:
undetectable		 5tiwB-1mhsA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6F_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		5 / 12 ILE A 664
ALA A 354
LEU A 363
THR A 680
ILE A 684
 None
 1.25A 5z6fA-1mhsA:
undetectable		 5z6fA-1mhsA:
11.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_A_HISA402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		5 / 10 GLY A 349
THR A 343
VAL A 169
ALA A 165
LEU A 172
 None
 0.97A 6czmA-1mhsA:
undetectable
6czmC-1mhsA:
undetectable		 6czmA-1mhsA:
20.90
6czmC-1mhsA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_S_PCFS603_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 1mhs PLASMA MEMBRANE
ATPASE
(Neurospora
crassa) 		4 / 7 GLY A 816
PHE A 818
VAL A 874
SER A 820
 None
 1.06A 6hu9S-1mhsA:
0.0
6hu9q-1mhsA:
1.2		 6hu9S-1mhsA:
6.73
6hu9q-1mhsA:
9.35