SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mhz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		5 / 10 ALA D 171
PHE D 358
ASN D 155
VAL D 220
ILE D 154
 None
 1.31A 1claA-1mhzD:
0.0		 1claA-1mhzD:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.36A 1k2rA-1mhzD:
0.0
1k2rB-1mhzD:
0.0		 1k2rA-1mhzD:
20.89
1k2rB-1mhzD:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.34A 1k2rA-1mhzD:
0.0
1k2rB-1mhzD:
0.0		 1k2rA-1mhzD:
20.89
1k2rB-1mhzD:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.37A 1k2sA-1mhzD:
0.0
1k2sB-1mhzD:
undetectable		 1k2sA-1mhzD:
20.89
1k2sB-1mhzD:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.31A 1k2sA-1mhzD:
0.0
1k2sB-1mhzD:
0.0		 1k2sA-1mhzD:
20.89
1k2sB-1mhzD:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.32A 1k2tA-1mhzD:
undetectable
1k2tB-1mhzD:
undetectable		 1k2tA-1mhzD:
20.89
1k2tB-1mhzD:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.34A 1k2tA-1mhzD:
undetectable
1k2tB-1mhzD:
undetectable		 1k2tA-1mhzD:
20.89
1k2tB-1mhzD:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.34A 1k2uA-1mhzD:
0.0
1k2uB-1mhzD:
0.0		 1k2uA-1mhzD:
20.89
1k2uB-1mhzD:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.32A 1k2uA-1mhzD:
0.0
1k2uB-1mhzD:
0.0		 1k2uA-1mhzD:
20.89
1k2uB-1mhzD:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT3_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 LEU D 448
TYR D 464
LEU D 458
GLN D 456
 None
 1.06A 1kt3A-1mhzD:
0.0		 1kt3A-1mhzD:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.33A 1lzxA-1mhzD:
undetectable
1lzxB-1mhzD:
undetectable		 1lzxA-1mhzD:
20.89
1lzxB-1mhzD:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.30A 1lzxA-1mhzD:
0.0
1lzxB-1mhzD:
0.0		 1lzxA-1mhzD:
20.89
1lzxB-1mhzD:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.30A 1lzzA-1mhzD:
undetectable
1lzzB-1mhzD:
undetectable		 1lzzA-1mhzD:
20.89
1lzzB-1mhzD:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.32A 1lzzA-1mhzD:
undetectable
1lzzB-1mhzD:
undetectable		 1lzzA-1mhzD:
20.89
1lzzB-1mhzD:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.32A 1m00A-1mhzD:
0.0
1m00B-1mhzD:
0.0		 1m00A-1mhzD:
20.89
1m00B-1mhzD:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.33A 1m00A-1mhzD:
undetectable
1m00B-1mhzD:
undetectable		 1m00A-1mhzD:
20.89
1m00B-1mhzD:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.34A 1mmvA-1mhzD:
undetectable
1mmvB-1mhzD:
undetectable		 1mmvA-1mhzD:
20.89
1mmvB-1mhzD:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.36A 1mmvA-1mhzD:
undetectable
1mmvB-1mhzD:
undetectable		 1mmvA-1mhzD:
20.89
1mmvB-1mhzD:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.31A 1mmwA-1mhzD:
0.0
1mmwB-1mhzD:
0.0		 1mmwA-1mhzD:
20.89
1mmwB-1mhzD:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.31A 1mmwA-1mhzD:
0.0
1mmwB-1mhzD:
0.0		 1mmwA-1mhzD:
20.89
1mmwB-1mhzD:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA734_1
(ALPHA AMYLASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 TRP D 371
HIS D 344
TYR D 376
GLY D 378
 None
 1.42A 1mxdA-1mhzD:
undetectable		 1mxdA-1mhzD:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.33A 1om4A-1mhzD:
undetectable
1om4B-1mhzD:
undetectable		 1om4A-1mhzD:
20.85
1om4B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.32A 1om4A-1mhzD:
undetectable
1om4B-1mhzD:
undetectable		 1om4A-1mhzD:
20.85
1om4B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 8 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.37A 1om5A-1mhzD:
0.0
1om5B-1mhzD:
0.0		 1om5A-1mhzD:
20.89
1om5B-1mhzD:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.35A 1om5A-1mhzD:
0.0
1om5B-1mhzD:
0.0		 1om5A-1mhzD:
20.89
1om5B-1mhzD:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.35A 1p6hA-1mhzD:
0.0
1p6hB-1mhzD:
0.0		 1p6hA-1mhzD:
20.89
1p6hB-1mhzD:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.32A 1p6hA-1mhzD:
0.0
1p6hB-1mhzD:
0.0		 1p6hA-1mhzD:
20.89
1p6hB-1mhzD:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.34A 1p6iA-1mhzD:
0.0
1p6iB-1mhzD:
0.0		 1p6iA-1mhzD:
20.89
1p6iB-1mhzD:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.35A 1p6iA-1mhzD:
0.0
1p6iB-1mhzD:
0.0		 1p6iA-1mhzD:
20.89
1p6iB-1mhzD:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.34A 1p6jA-1mhzD:
undetectable
1p6jB-1mhzD:
undetectable		 1p6jA-1mhzD:
20.89
1p6jB-1mhzD:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.36A 1p6jA-1mhzD:
0.0
1p6jB-1mhzD:
0.0		 1p6jA-1mhzD:
20.89
1p6jB-1mhzD:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.34A 1p6kA-1mhzD:
0.0
1p6kB-1mhzD:
0.0		 1p6kA-1mhzD:
20.89
1p6kB-1mhzD:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.32A 1p6kA-1mhzD:
0.0
1p6kB-1mhzD:
0.0		 1p6kA-1mhzD:
20.89
1p6kB-1mhzD:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_1
(DNA TOPOISOMERASE II)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 HIS D 163
THR D 501
LEU D 506
GLN D 498
 None
 1.11A 1qzrA-1mhzD:
undetectable		 1qzrA-1mhzD:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_2
(DNA TOPOISOMERASE II)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 HIS D 163
THR D 501
LEU D 506
GLN D 498
 None
 1.11A 1qzrB-1mhzD:
undetectable		 1qzrB-1mhzD:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.35A 1rs6A-1mhzD:
0.0
1rs6B-1mhzD:
0.0		 1rs6A-1mhzD:
20.89
1rs6B-1mhzD:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 8 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.32A 1rs6A-1mhzD:
undetectable
1rs6B-1mhzD:
undetectable		 1rs6A-1mhzD:
20.89
1rs6B-1mhzD:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.37A 1rs7A-1mhzD:
undetectable
1rs7B-1mhzD:
undetectable		 1rs7A-1mhzD:
20.89
1rs7B-1mhzD:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.34A 1rs7A-1mhzD:
0.0
1rs7B-1mhzD:
0.0		 1rs7A-1mhzD:
20.89
1rs7B-1mhzD:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVL_A_H4BA900_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.35A 1zvlA-1mhzD:
0.0
1zvlB-1mhzD:
0.0		 1zvlA-1mhzD:
20.93
1zvlB-1mhzD:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVL_B_H4BB920_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.35A 1zvlA-1mhzD:
0.0
1zvlB-1mhzD:
0.0		 1zvlA-1mhzD:
20.93
1zvlB-1mhzD:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.32A 1zzqA-1mhzD:
undetectable
1zzqB-1mhzD:
undetectable		 1zzqA-1mhzD:
20.85
1zzqB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.32A 1zzqA-1mhzD:
undetectable
1zzqB-1mhzD:
undetectable		 1zzqA-1mhzD:
20.85
1zzqB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 8 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.31A 2g6hA-1mhzD:
undetectable
2g6hB-1mhzD:
undetectable		 2g6hA-1mhzD:
20.85
2g6hB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.33A 2g6hA-1mhzD:
0.0
2g6hB-1mhzD:
0.0		 2g6hA-1mhzD:
20.85
2g6hB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.31A 2g6kA-1mhzD:
0.0
2g6kB-1mhzD:
0.0		 2g6kA-1mhzD:
20.85
2g6kB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.35A 2g6kA-1mhzD:
undetectable
2g6kB-1mhzD:
undetectable		 2g6kA-1mhzD:
20.85
2g6kB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.33A 2g6mA-1mhzD:
0.0
2g6mB-1mhzD:
0.0		 2g6mA-1mhzD:
20.85
2g6mB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.34A 2g6mA-1mhzD:
0.0
2g6mB-1mhzD:
0.0		 2g6mA-1mhzD:
20.85
2g6mB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX3_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.33A 2hx3A-1mhzD:
0.0
2hx3B-1mhzD:
0.0		 2hx3A-1mhzD:
20.85
2hx3B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX3_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.40A 2hx3A-1mhzD:
0.0
2hx3B-1mhzD:
0.0		 2hx3A-1mhzD:
20.85
2hx3B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.35A 2hx4A-1mhzD:
0.0
2hx4B-1mhzD:
0.0		 2hx4A-1mhzD:
20.85
2hx4B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.37A 2hx4A-1mhzD:
0.0
2hx4B-1mhzD:
0.0		 2hx4A-1mhzD:
20.85
2hx4B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_CCSB417_0
(ESTROGEN RECEPTOR)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		3 / 3 GLN D 422
LYS D 185
VAL D 187
 None
 0.83A 2jfaB-1mhzD:
0.2		 2jfaB-1mhzD:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_A_HSMA145_1
(D7R4 PROTEIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 ILE D 459
ARG D 463
ASP D 196
GLU D 199
 None
 1.16A 2qebA-1mhzD:
0.0		 2qebA-1mhzD:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1500_1
(CYTOCHROME P450 3A4)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		5 / 11 LEU D 204
ILE D 193
PHE D 192
ALA D 189
GLU D 460
 None
 1.21A 2v0mA-1mhzD:
0.0		 2v0mA-1mhzD:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1498_1
(CYTOCHROME P450 3A4)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		5 / 11 LEU D 204
ILE D 193
PHE D 192
ALA D 189
GLU D 460
 None
 1.27A 2v0mD-1mhzD:
1.4		 2v0mD-1mhzD:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1161_1
(ALLERGEN ARG R 1)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 5 TYR D 405
VAL D 415
ASP D 414
SER D 428
 None
 0.71A 2x45A-1mhzD:
0.0		 2x45A-1mhzD:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1161_1
(ALLERGEN ARG R 1)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 5 TYR D 405
VAL D 415
ASP D 414
SER D 428
 None
 0.70A 2x45C-1mhzD:
undetectable		 2x45C-1mhzD:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_B_J01B500_1
(ORF12)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		5 / 9 VAL D 239
ILE D 217
LEU D 204
GLY D 113
ALA D 117
 None
 1.30A 2xf3B-1mhzD:
0.0		 2xf3B-1mhzD:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_B_J01B500_1
(ORF12)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		5 / 9 VAL D 239
ILE D 217
LEU D 204
GLY D 113
ALA D 117
 None
 1.32A 2xfsB-1mhzD:
0.0		 2xfsB-1mhzD:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_B_J01B1436_1
(ORF12)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		5 / 9 VAL D 239
ILE D 217
LEU D 204
GLY D 113
ALA D 117
 None
 1.29A 2xh9B-1mhzD:
0.0		 2xh9B-1mhzD:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMB_A_PXBA692_1
(LACTOTRANSFERRIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		3 / 3 PRO D 300
GLU D 373
TYR D 376
 None
 0.68A 2zmbA-1mhzD:
undetectable		 2zmbA-1mhzD:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		5 / 12 TYR D 115
ARG D 175
GLY D 113
ASP D 242
VAL D 239
 None
 1.23A 2zznA-1mhzD:
0.0		 2zznA-1mhzD:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		5 / 8 ILE D 318
LEU D 321
ARG D 330
THR D 269
LEU D 267
 None
 1.49A 3abkA-1mhzD:
1.7
3abkJ-1mhzD:
undetectable		 3abkA-1mhzD:
21.42
3abkJ-1mhzD:
6.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.35A 3b3mA-1mhzD:
0.0
3b3mB-1mhzD:
0.0		 3b3mA-1mhzD:
20.85
3b3mB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.34A 3b3mA-1mhzD:
0.0
3b3mB-1mhzD:
0.0		 3b3mA-1mhzD:
20.85
3b3mB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.33A 3b3nA-1mhzD:
undetectable
3b3nB-1mhzD:
undetectable		 3b3nA-1mhzD:
20.85
3b3nB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.32A 3b3nA-1mhzD:
undetectable
3b3nB-1mhzD:
undetectable		 3b3nA-1mhzD:
20.85
3b3nB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.35A 3b3oA-1mhzD:
undetectable
3b3oB-1mhzD:
undetectable		 3b3oA-1mhzD:
20.85
3b3oB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.35A 3b3oA-1mhzD:
0.0
3b3oB-1mhzD:
0.0		 3b3oA-1mhzD:
20.85
3b3oB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.37A 3b3pA-1mhzD:
0.0
3b3pB-1mhzD:
0.0		 3b3pA-1mhzD:
20.85
3b3pB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 8 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.34A 3b3pA-1mhzD:
undetectable
3b3pB-1mhzD:
undetectable		 3b3pA-1mhzD:
20.85
3b3pB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWC_B_SAMB501_1
(SPERMIDINE SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 5 GLN D  33
GLN D 133
ASP D  38
THR D 129
 None
 1.48A 3bwcB-1mhzD:
undetectable		 3bwcB-1mhzD:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_O_SAMO302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		5 / 12 LEU D 206
GLY D 314
VAL D 309
LEU D 271
LEU D 267
 None
 0.97A 3cjtO-1mhzD:
undetectable		 3cjtO-1mhzD:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.32A 3fc5A-1mhzD:
0.0
3fc5B-1mhzD:
0.0		 3fc5A-1mhzD:
20.85
3fc5B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.32A 3fc5A-1mhzD:
undetectable
3fc5B-1mhzD:
undetectable		 3fc5A-1mhzD:
20.85
3fc5B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.34A 3hsnA-1mhzD:
undetectable
3hsnB-1mhzD:
undetectable		 3hsnA-1mhzD:
20.85
3hsnB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.31A 3hsnA-1mhzD:
undetectable
3hsnB-1mhzD:
undetectable		 3hsnA-1mhzD:
20.85
3hsnB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.32A 3hsoA-1mhzD:
undetectable
3hsoB-1mhzD:
undetectable		 3hsoA-1mhzD:
20.85
3hsoB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.33A 3hsoA-1mhzD:
undetectable
3hsoB-1mhzD:
undetectable		 3hsoA-1mhzD:
20.85
3hsoB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.32A 3hspA-1mhzD:
undetectable
3hspB-1mhzD:
undetectable		 3hspA-1mhzD:
20.85
3hspB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.35A 3hspA-1mhzD:
0.0
3hspB-1mhzD:
0.0		 3hspA-1mhzD:
20.85
3hspB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.39A 3jt3A-1mhzD:
0.0
3jt3B-1mhzD:
0.0		 3jt3A-1mhzD:
20.85
3jt3B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.38A 3jt3A-1mhzD:
undetectable
3jt3B-1mhzD:
undetectable		 3jt3A-1mhzD:
20.85
3jt3B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.36A 3jt4A-1mhzD:
0.0
3jt4B-1mhzD:
0.0		 3jt4A-1mhzD:
20.85
3jt4B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.35A 3jt4A-1mhzD:
0.0
3jt4B-1mhzD:
0.0		 3jt4A-1mhzD:
20.85
3jt4B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.36A 3jt5A-1mhzD:
undetectable
3jt5B-1mhzD:
undetectable		 3jt5A-1mhzD:
20.85
3jt5B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.37A 3jt5A-1mhzD:
0.0
3jt5B-1mhzD:
0.0		 3jt5A-1mhzD:
20.85
3jt5B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.40A 3jt6A-1mhzD:
0.0
3jt6B-1mhzD:
0.0		 3jt6A-1mhzD:
20.85
3jt6B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.43A 3jt6A-1mhzD:
0.0
3jt6B-1mhzD:
0.0		 3jt6A-1mhzD:
20.85
3jt6B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.38A 3jt7A-1mhzD:
undetectable
3jt7B-1mhzD:
undetectable		 3jt7A-1mhzD:
20.85
3jt7B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.36A 3jt7A-1mhzD:
0.0
3jt7B-1mhzD:
0.0		 3jt7A-1mhzD:
20.85
3jt7B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.34A 3jt8A-1mhzD:
undetectable
3jt8B-1mhzD:
undetectable		 3jt8A-1mhzD:
20.85
3jt8B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.34A 3jt8A-1mhzD:
undetectable
3jt8B-1mhzD:
undetectable		 3jt8A-1mhzD:
20.85
3jt8B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.35A 3jt9A-1mhzD:
undetectable
3jt9B-1mhzD:
undetectable		 3jt9A-1mhzD:
20.85
3jt9B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.34A 3jt9A-1mhzD:
undetectable
3jt9B-1mhzD:
undetectable		 3jt9A-1mhzD:
20.85
3jt9B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.39A 3jtaA-1mhzD:
0.0
3jtaB-1mhzD:
0.0		 3jtaA-1mhzD:
20.85
3jtaB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.36A 3jtaA-1mhzD:
undetectable
3jtaB-1mhzD:
undetectable		 3jtaA-1mhzD:
20.85
3jtaB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.41A 3jwsA-1mhzD:
0.0
3jwsB-1mhzD:
0.0		 3jwsA-1mhzD:
20.85
3jwsB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.41A 3jwsA-1mhzD:
undetectable
3jwsB-1mhzD:
undetectable		 3jwsA-1mhzD:
20.85
3jwsB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.43A 3jwtA-1mhzD:
undetectable
3jwtB-1mhzD:
undetectable		 3jwtA-1mhzD:
20.85
3jwtB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.42A 3jwtA-1mhzD:
undetectable
3jwtB-1mhzD:
undetectable		 3jwtA-1mhzD:
20.85
3jwtB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.43A 3jx0A-1mhzD:
0.0
3jx0B-1mhzD:
0.0		 3jx0A-1mhzD:
20.85
3jx0B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.41A 3jx0A-1mhzD:
undetectable
3jx0B-1mhzD:
undetectable		 3jx0A-1mhzD:
20.85
3jx0B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.44A 3jx1A-1mhzD:
0.0
3jx1B-1mhzD:
0.0		 3jx1A-1mhzD:
20.85
3jx1B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		3 / 3 LEU D 206
TRP D 313
GLY D 314
 None
 0.80A 3l35B-1mhzD:
0.0
3l35K-1mhzD:
undetectable		 3l35B-1mhzD:
6.55
3l35K-1mhzD:
3.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.36A 3n2rA-1mhzD:
undetectable
3n2rB-1mhzD:
undetectable		 3n2rA-1mhzD:
20.85
3n2rB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.35A 3n2rA-1mhzD:
undetectable
3n2rB-1mhzD:
undetectable		 3n2rA-1mhzD:
20.85
3n2rB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.39A 3n5yA-1mhzD:
0.0
3n5yB-1mhzD:
0.0		 3n5yA-1mhzD:
20.85
3n5yB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.38A 3n5yA-1mhzD:
0.0
3n5yB-1mhzD:
0.0		 3n5yA-1mhzD:
20.85
3n5yB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.42A 3n5zA-1mhzD:
0.0
3n5zB-1mhzD:
0.0		 3n5zA-1mhzD:
20.85
3n5zB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.46A 3n61A-1mhzD:
0.0
3n61B-1mhzD:
0.0		 3n61A-1mhzD:
20.85
3n61B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.43A 3n65A-1mhzD:
0.0
3n65B-1mhzD:
0.0		 3n65A-1mhzD:
21.03
3n65B-1mhzD:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.45A 3nlkA-1mhzD:
undetectable
3nlkB-1mhzD:
undetectable		 3nlkA-1mhzD:
20.85
3nlkB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.38A 3nlmA-1mhzD:
undetectable
3nlmB-1mhzD:
undetectable		 3nlmA-1mhzD:
20.85
3nlmB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.41A 3nlmA-1mhzD:
0.0
3nlmB-1mhzD:
0.0		 3nlmA-1mhzD:
20.85
3nlmB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.43A 3nlvA-1mhzD:
undetectable
3nlvB-1mhzD:
undetectable		 3nlvA-1mhzD:
20.85
3nlvB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.42A 3nlvA-1mhzD:
0.0
3nlvB-1mhzD:
0.0		 3nlvA-1mhzD:
20.85
3nlvB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.40A 3nlwA-1mhzD:
0.0
3nlwB-1mhzD:
0.0		 3nlwA-1mhzD:
20.85
3nlwB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.38A 3nlwA-1mhzD:
undetectable
3nlwB-1mhzD:
undetectable		 3nlwA-1mhzD:
20.85
3nlwB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.39A 3nlxA-1mhzD:
0.0
3nlxB-1mhzD:
0.0		 3nlxA-1mhzD:
20.85
3nlxB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.39A 3nlxA-1mhzD:
undetectable
3nlxB-1mhzD:
undetectable		 3nlxA-1mhzD:
20.85
3nlxB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.44A 3nlyA-1mhzD:
0.0
3nlyB-1mhzD:
0.0		 3nlyA-1mhzD:
20.85
3nlyB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.41A 3nlzA-1mhzD:
0.0
3nlzB-1mhzD:
0.0		 3nlzA-1mhzD:
20.85
3nlzB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.40A 3nlzA-1mhzD:
0.0
3nlzB-1mhzD:
0.0		 3nlzA-1mhzD:
20.85
3nlzB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.39A 3nm0A-1mhzD:
undetectable
3nm0B-1mhzD:
undetectable		 3nm0A-1mhzD:
20.85
3nm0B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.38A 3nm0A-1mhzD:
0.0
3nm0B-1mhzD:
0.0		 3nm0A-1mhzD:
20.85
3nm0B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.41A 3nnyA-1mhzD:
undetectable
3nnyB-1mhzD:
undetectable		 3nnyA-1mhzD:
20.85
3nnyB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.42A 3nnyA-1mhzD:
undetectable
3nnyB-1mhzD:
undetectable		 3nnyA-1mhzD:
20.85
3nnyB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.40A 3nnzA-1mhzD:
0.0
3nnzB-1mhzD:
0.0		 3nnzA-1mhzD:
20.85
3nnzB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.40A 3nnzA-1mhzD:
undetectable
3nnzB-1mhzD:
undetectable		 3nnzA-1mhzD:
20.85
3nnzB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_2
(CYTOCHROME P450 3A4)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 ARG D 419
ILE D 417
THR D 277
ARG D 463
 None
 1.29A 3nxuA-1mhzD:
0.0		 3nxuA-1mhzD:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.44A 3pneA-1mhzD:
0.0
3pneB-1mhzD:
0.0		 3pneA-1mhzD:
20.85
3pneB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.40A 3pneA-1mhzD:
0.0
3pneB-1mhzD:
0.0		 3pneA-1mhzD:
20.85
3pneB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.38A 3pnfA-1mhzD:
undetectable
3pnfB-1mhzD:
undetectable		 3pnfA-1mhzD:
20.85
3pnfB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.38A 3pnfA-1mhzD:
0.0
3pnfB-1mhzD:
0.0		 3pnfA-1mhzD:
20.85
3pnfB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.42A 3pngA-1mhzD:
0.0
3pngB-1mhzD:
0.0		 3pngA-1mhzD:
20.85
3pngB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.39A 3pngA-1mhzD:
undetectable
3pngB-1mhzD:
undetectable		 3pngA-1mhzD:
20.85
3pngB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.38A 3q99A-1mhzD:
undetectable
3q99B-1mhzD:
undetectable		 3q99A-1mhzD:
20.85
3q99B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.36A 3q99A-1mhzD:
undetectable
3q99B-1mhzD:
undetectable		 3q99A-1mhzD:
20.85
3q99B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.38A 3q9aA-1mhzD:
undetectable
3q9aB-1mhzD:
undetectable		 3q9aA-1mhzD:
20.85
3q9aB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.36A 3q9aA-1mhzD:
0.0
3q9aB-1mhzD:
0.0		 3q9aA-1mhzD:
20.85
3q9aB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.39A 3rqjA-1mhzD:
0.0
3rqjB-1mhzD:
0.0		 3rqjA-1mhzD:
20.85
3rqjB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.40A 3rqjA-1mhzD:
0.0
3rqjB-1mhzD:
0.0		 3rqjA-1mhzD:
20.85
3rqjB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.44A 3rqkA-1mhzD:
0.0
3rqkB-1mhzD:
0.0		 3rqkA-1mhzD:
20.85
3rqkB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.38A 3rqkA-1mhzD:
0.0
3rqkB-1mhzD:
0.0		 3rqkA-1mhzD:
20.85
3rqkB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.39A 3rqlA-1mhzD:
0.0
3rqlB-1mhzD:
0.0		 3rqlA-1mhzD:
20.85
3rqlB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.39A 3rqmA-1mhzD:
undetectable
3rqmB-1mhzD:
undetectable		 3rqmA-1mhzD:
20.85
3rqmB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.39A 3rqmA-1mhzD:
undetectable
3rqmB-1mhzD:
undetectable		 3rqmA-1mhzD:
20.85
3rqmB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.40A 3rqnA-1mhzD:
undetectable
3rqnB-1mhzD:
undetectable		 3rqnA-1mhzD:
20.85
3rqnB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.37A 3rqnA-1mhzD:
undetectable
3rqnB-1mhzD:
undetectable		 3rqnA-1mhzD:
20.85
3rqnB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		5 / 12 GLY D 167
ASP D 164
ARG D 502
GLY D 357
ALA D 359
 None
 1.08A 3sudA-1mhzD:
undetectable		 3sudA-1mhzD:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUG_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		5 / 12 GLY D 167
ASP D 164
ARG D 502
GLY D 357
ALA D 359
 None
 1.06A 3sugA-1mhzD:
undetectable		 3sugA-1mhzD:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.41A 3svpA-1mhzD:
0.0
3svpB-1mhzD:
0.0		 3svpA-1mhzD:
20.85
3svpB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.39A 3svpA-1mhzD:
0.0
3svpB-1mhzD:
0.0		 3svpA-1mhzD:
20.85
3svpB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.41A 3svqA-1mhzD:
0.0
3svqB-1mhzD:
0.0		 3svqA-1mhzD:
20.85
3svqB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.41A 3svqA-1mhzD:
0.0
3svqB-1mhzD:
0.0		 3svqA-1mhzD:
20.85
3svqB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.36A 3tylA-1mhzD:
undetectable
3tylB-1mhzD:
undetectable		 3tylA-1mhzD:
20.85
3tylB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.34A 3tylA-1mhzD:
undetectable
3tylB-1mhzD:
undetectable		 3tylA-1mhzD:
20.85
3tylB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.37A 3tymA-1mhzD:
undetectable
3tymB-1mhzD:
undetectable		 3tymA-1mhzD:
20.85
3tymB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.37A 3tymA-1mhzD:
undetectable
3tymB-1mhzD:
undetectable		 3tymA-1mhzD:
20.85
3tymB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.36A 3tynA-1mhzD:
undetectable
3tynB-1mhzD:
undetectable		 3tynA-1mhzD:
20.85
3tynB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.41A 3tynA-1mhzD:
undetectable
3tynB-1mhzD:
undetectable		 3tynA-1mhzD:
20.85
3tynB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.39A 3tyoA-1mhzD:
0.0
3tyoB-1mhzD:
0.0		 3tyoA-1mhzD:
20.85
3tyoB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.37A 3tyoA-1mhzD:
undetectable
3tyoB-1mhzD:
undetectable		 3tyoA-1mhzD:
20.85
3tyoB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.41A 3ufoA-1mhzD:
0.0
3ufoB-1mhzD:
0.0		 3ufoA-1mhzD:
20.85
3ufoB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.39A 3ufqA-1mhzD:
0.0
3ufqB-1mhzD:
0.0		 3ufqA-1mhzD:
20.85
3ufqB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.41A 3ufqA-1mhzD:
0.0
3ufqB-1mhzD:
0.0		 3ufqA-1mhzD:
20.85
3ufqB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.41A 3ufsA-1mhzD:
0.0
3ufsB-1mhzD:
0.0		 3ufsA-1mhzD:
20.85
3ufsB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.46A 3uftA-1mhzD:
0.0
3uftB-1mhzD:
0.0		 3uftA-1mhzD:
20.85
3uftB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.42A 3uftA-1mhzD:
0.0
3uftB-1mhzD:
0.0		 3uftA-1mhzD:
20.85
3uftB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.39A 3ufuA-1mhzD:
undetectable
3ufuB-1mhzD:
undetectable		 3ufuA-1mhzD:
20.85
3ufuB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.37A 3ufuA-1mhzD:
0.0
3ufuB-1mhzD:
0.0		 3ufuA-1mhzD:
20.85
3ufuB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.41A 3ufvA-1mhzD:
undetectable
3ufvB-1mhzD:
undetectable		 3ufvA-1mhzD:
20.85
3ufvB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.37A 3ufvA-1mhzD:
0.0
3ufvB-1mhzD:
0.0		 3ufvA-1mhzD:
20.85
3ufvB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.35A 3ufwA-1mhzD:
0.0
3ufwB-1mhzD:
0.0		 3ufwA-1mhzD:
20.85
3ufwB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.40A 3ufwA-1mhzD:
0.0
3ufwB-1mhzD:
0.0		 3ufwA-1mhzD:
20.85
3ufwB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 5 ASP D 164
GLY D 167
TYR D 162
GLU D 101
 None
 1.49A 3w9tA-1mhzD:
0.0		 3w9tA-1mhzD:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 5 ASP D 164
GLY D 167
TYR D 162
GLU D 101
 None
 1.48A 3w9tC-1mhzD:
0.0		 3w9tC-1mhzD:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 5 ASP D 164
GLY D 167
TYR D 162
GLU D 101
 None
 1.48A 3w9tD-1mhzD:
0.0		 3w9tD-1mhzD:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 5 ASP D 164
GLY D 167
TYR D 162
GLU D 101
 None
 1.48A 3w9tG-1mhzD:
0.0		 3w9tG-1mhzD:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		3 / 3 TRP D 308
TRP D 301
THR D 283
 None
 1.45A 4bboB-1mhzD:
0.0		 4bboB-1mhzD:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.43A 4c39A-1mhzD:
0.0
4c39B-1mhzD:
0.0		 4c39A-1mhzD:
20.85
4c39B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.41A 4c39A-1mhzD:
0.0
4c39B-1mhzD:
0.0		 4c39A-1mhzD:
20.85
4c39B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_A_CAMA1419_0
(CYTOCHROME P450)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 8 THR D 234
LEU D  89
LEU D  86
GLY D  85
 None
 0.62A 4c9nA-1mhzD:
0.0		 4c9nA-1mhzD:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.44A 4camA-1mhzD:
0.0
4camB-1mhzD:
0.0		 4camA-1mhzD:
20.85
4camB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.40A 4camA-1mhzD:
undetectable
4camB-1mhzD:
undetectable		 4camA-1mhzD:
20.85
4camB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.42A 4canA-1mhzD:
undetectable
4canB-1mhzD:
undetectable		 4canA-1mhzD:
20.85
4canB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.37A 4canA-1mhzD:
0.0
4canB-1mhzD:
0.0		 4canA-1mhzD:
20.85
4canB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.39A 4caoA-1mhzD:
0.0
4caoB-1mhzD:
0.0		 4caoA-1mhzD:
20.85
4caoB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.39A 4caoA-1mhzD:
0.0
4caoB-1mhzD:
0.0		 4caoA-1mhzD:
20.85
4caoB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.39A 4capA-1mhzD:
0.0
4capB-1mhzD:
0.0		 4capA-1mhzD:
20.85
4capB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 8 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.39A 4capA-1mhzD:
0.0
4capB-1mhzD:
0.0		 4capA-1mhzD:
20.85
4capB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.36A 4caqA-1mhzD:
0.0
4caqB-1mhzD:
0.0		 4caqA-1mhzD:
20.85
4caqB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.36A 4caqA-1mhzD:
0.0
4caqB-1mhzD:
0.0		 4caqA-1mhzD:
20.85
4caqB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.38A 4cdtA-1mhzD:
0.0
4cdtB-1mhzD:
0.0		 4cdtA-1mhzD:
20.85
4cdtB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.37A 4cdtA-1mhzD:
0.0
4cdtB-1mhzD:
0.0		 4cdtA-1mhzD:
20.85
4cdtB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.41A 4ctpA-1mhzD:
0.0
4ctpB-1mhzD:
0.0		 4ctpA-1mhzD:
20.85
4ctpB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.39A 4ctpA-1mhzD:
undetectable
4ctpB-1mhzD:
undetectable		 4ctpA-1mhzD:
20.85
4ctpB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.36A 4ctqA-1mhzD:
0.0
4ctqB-1mhzD:
0.0		 4ctqA-1mhzD:
20.85
4ctqB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.39A 4ctqA-1mhzD:
undetectable
4ctqB-1mhzD:
undetectable		 4ctqA-1mhzD:
20.85
4ctqB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.40A 4cttA-1mhzD:
0.0
4cttB-1mhzD:
0.0		 4cttA-1mhzD:
20.85
4cttB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.44A 4ctuA-1mhzD:
undetectable
4ctuB-1mhzD:
undetectable		 4ctuA-1mhzD:
20.85
4ctuB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.40A 4ctuA-1mhzD:
undetectable
4ctuB-1mhzD:
undetectable		 4ctuA-1mhzD:
20.85
4ctuB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.38A 4ctvA-1mhzD:
undetectable
4ctvB-1mhzD:
undetectable		 4ctvA-1mhzD:
20.85
4ctvB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.38A 4ctvA-1mhzD:
0.0
4ctvB-1mhzD:
0.0		 4ctvA-1mhzD:
20.85
4ctvB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.37A 4ctwA-1mhzD:
undetectable
4ctwB-1mhzD:
undetectable		 4ctwA-1mhzD:
20.85
4ctwB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.38A 4ctwA-1mhzD:
0.0
4ctwB-1mhzD:
0.0		 4ctwA-1mhzD:
20.85
4ctwB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.38A 4ctxA-1mhzD:
undetectable
4ctxB-1mhzD:
undetectable		 4ctxA-1mhzD:
20.85
4ctxB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.37A 4ctxA-1mhzD:
undetectable
4ctxB-1mhzD:
undetectable		 4ctxA-1mhzD:
20.85
4ctxB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.39A 4cx5A-1mhzD:
0.0
4cx5B-1mhzD:
0.0		 4cx5A-1mhzD:
20.85
4cx5B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.38A 4cx5A-1mhzD:
undetectable
4cx5B-1mhzD:
undetectable		 4cx5A-1mhzD:
20.85
4cx5B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.38A 4cx6A-1mhzD:
0.0
4cx6B-1mhzD:
0.0		 4cx6A-1mhzD:
20.85
4cx6B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.36A 4cx6A-1mhzD:
undetectable
4cx6B-1mhzD:
undetectable		 4cx6A-1mhzD:
20.85
4cx6B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.37A 4d1nA-1mhzD:
undetectable
4d1nB-1mhzD:
undetectable		 4d1nA-1mhzD:
20.82
4d1nB-1mhzD:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.37A 4d1nA-1mhzD:
0.0
4d1nB-1mhzD:
0.0		 4d1nA-1mhzD:
20.82
4d1nB-1mhzD:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.35A 4d1nC-1mhzD:
0.0
4d1nD-1mhzD:
0.0		 4d1nC-1mhzD:
20.82
4d1nD-1mhzD:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.36A 4d1nC-1mhzD:
0.0
4d1nD-1mhzD:
0.0		 4d1nC-1mhzD:
20.82
4d1nD-1mhzD:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.37A 4d2yA-1mhzD:
undetectable
4d2yB-1mhzD:
undetectable		 4d2yA-1mhzD:
20.85
4d2yB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.37A 4d2yA-1mhzD:
undetectable
4d2yB-1mhzD:
undetectable		 4d2yA-1mhzD:
20.85
4d2yB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.39A 4d2zA-1mhzD:
0.0
4d2zB-1mhzD:
0.0		 4d2zA-1mhzD:
20.85
4d2zB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.39A 4d2zA-1mhzD:
undetectable
4d2zB-1mhzD:
undetectable		 4d2zA-1mhzD:
20.85
4d2zB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.36A 4d30A-1mhzD:
undetectable
4d30B-1mhzD:
undetectable		 4d30A-1mhzD:
20.85
4d30B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.37A 4d30A-1mhzD:
undetectable
4d30B-1mhzD:
undetectable		 4d30A-1mhzD:
20.85
4d30B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.35A 4d31A-1mhzD:
0.0
4d31B-1mhzD:
0.0		 4d31A-1mhzD:
20.85
4d31B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.34A 4d31A-1mhzD:
0.0
4d31B-1mhzD:
0.0		 4d31A-1mhzD:
20.85
4d31B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.42A 4d32A-1mhzD:
0.0
4d32B-1mhzD:
0.0		 4d32A-1mhzD:
20.85
4d32B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.35A 4d3bA-1mhzD:
undetectable
4d3bB-1mhzD:
undetectable		 4d3bA-1mhzD:
20.85
4d3bB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.35A 4d3bA-1mhzD:
0.0
4d3bB-1mhzD:
0.0		 4d3bA-1mhzD:
20.85
4d3bB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.37A 4d7oA-1mhzD:
0.0
4d7oB-1mhzD:
0.0		 4d7oA-1mhzD:
20.85
4d7oB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.36A 4d7oA-1mhzD:
undetectable
4d7oB-1mhzD:
undetectable		 4d7oA-1mhzD:
20.85
4d7oB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.37A 4euxA-1mhzD:
0.0
4euxB-1mhzD:
0.0		 4euxA-1mhzD:
20.85
4euxB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.38A 4euxA-1mhzD:
0.0
4euxB-1mhzD:
0.0		 4euxA-1mhzD:
20.85
4euxB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.34A 4fvwA-1mhzD:
undetectable
4fvwB-1mhzD:
undetectable		 4fvwA-1mhzD:
20.85
4fvwB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.33A 4fvwA-1mhzD:
undetectable
4fvwB-1mhzD:
undetectable		 4fvwA-1mhzD:
20.85
4fvwB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.36A 4fvxA-1mhzD:
undetectable
4fvxB-1mhzD:
undetectable		 4fvxA-1mhzD:
20.85
4fvxB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.38A 4fvxA-1mhzD:
undetectable
4fvxB-1mhzD:
undetectable		 4fvxA-1mhzD:
20.85
4fvxB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.35A 4fvyA-1mhzD:
undetectable
4fvyB-1mhzD:
undetectable		 4fvyA-1mhzD:
20.85
4fvyB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.35A 4fvyA-1mhzD:
0.0
4fvyB-1mhzD:
0.0		 4fvyA-1mhzD:
20.85
4fvyB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.38A 4fvzA-1mhzD:
0.0
4fvzB-1mhzD:
0.0		 4fvzA-1mhzD:
20.85
4fvzB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.35A 4fvzA-1mhzD:
0.0
4fvzB-1mhzD:
0.0		 4fvzA-1mhzD:
20.85
4fvzB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.37A 4fw0A-1mhzD:
0.0
4fw0B-1mhzD:
0.0		 4fw0A-1mhzD:
20.85
4fw0B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.35A 4fw0A-1mhzD:
0.0
4fw0B-1mhzD:
0.0		 4fw0A-1mhzD:
20.85
4fw0B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.36A 4gqeA-1mhzD:
undetectable
4gqeB-1mhzD:
undetectable		 4gqeA-1mhzD:
20.85
4gqeB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.35A 4gqeA-1mhzD:
undetectable
4gqeB-1mhzD:
undetectable		 4gqeA-1mhzD:
20.85
4gqeB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA501_1
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		5 / 12 LYS D  74
ASP D  75
THR D 241
VAL D 239
GLU D 114
 None
None
None
None
FE  D 801 ( 2.7A)
 1.33A 4i41A-1mhzD:
undetectable		 4i41A-1mhzD:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.43A 4imtA-1mhzD:
0.0
4imtB-1mhzD:
0.0		 4imtA-1mhzD:
20.85
4imtB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.41A 4imtA-1mhzD:
0.0
4imtB-1mhzD:
0.0		 4imtA-1mhzD:
20.85
4imtB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.43A 4imuA-1mhzD:
0.0
4imuB-1mhzD:
0.0		 4imuA-1mhzD:
20.85
4imuB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMU_A_H4BA809_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.38A 4imuA-1mhzD:
0.0
4imuB-1mhzD:
0.0		 4imuA-1mhzD:
20.85
4imuB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSE_A_H4BA804_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.43A 4jseA-1mhzD:
0.0
4jseB-1mhzD:
0.0		 4jseA-1mhzD:
20.85
4jseB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.41A 4jseA-1mhzD:
0.0
4jseB-1mhzD:
0.0		 4jseA-1mhzD:
20.85
4jseB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.42A 4jsfA-1mhzD:
0.0
4jsfB-1mhzD:
0.0		 4jsfA-1mhzD:
20.85
4jsfB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.42A 4jsfA-1mhzD:
undetectable
4jsfB-1mhzD:
undetectable		 4jsfA-1mhzD:
20.85
4jsfB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.39A 4jsgA-1mhzD:
undetectable
4jsgB-1mhzD:
undetectable		 4jsgA-1mhzD:
20.85
4jsgB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.37A 4jsgA-1mhzD:
undetectable
4jsgB-1mhzD:
undetectable		 4jsgA-1mhzD:
20.85
4jsgB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.41A 4jshA-1mhzD:
0.0
4jshB-1mhzD:
0.0		 4jshA-1mhzD:
20.85
4jshB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.35A 4jsjA-1mhzD:
0.0
4jsjB-1mhzD:
0.0		 4jsjA-1mhzD:
20.85
4jsjB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.36A 4jsjA-1mhzD:
0.0
4jsjB-1mhzD:
0.0		 4jsjA-1mhzD:
20.85
4jsjB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.40A 4k5dA-1mhzD:
0.0
4k5dB-1mhzD:
0.0		 4k5dA-1mhzD:
20.85
4k5dB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.37A 4k5eA-1mhzD:
undetectable
4k5eB-1mhzD:
undetectable		 4k5eA-1mhzD:
20.85
4k5eB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.37A 4k5eA-1mhzD:
0.0
4k5eB-1mhzD:
0.0		 4k5eA-1mhzD:
20.85
4k5eB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.43A 4k5fA-1mhzD:
0.0
4k5fB-1mhzD:
0.0		 4k5fA-1mhzD:
20.85
4k5fB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.37A 4k5gA-1mhzD:
undetectable
4k5gB-1mhzD:
undetectable		 4k5gA-1mhzD:
20.85
4k5gB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.35A 4k5gA-1mhzD:
undetectable
4k5gB-1mhzD:
undetectable		 4k5gA-1mhzD:
20.85
4k5gB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.38A 4kchA-1mhzD:
0.0
4kchB-1mhzD:
0.0		 4kchA-1mhzD:
20.85
4kchB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.37A 4kchA-1mhzD:
0.0
4kchB-1mhzD:
0.0		 4kchA-1mhzD:
20.85
4kchB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.39A 4kciA-1mhzD:
0.0
4kciB-1mhzD:
0.0		 4kciA-1mhzD:
20.85
4kciB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.40A 4kciA-1mhzD:
0.0
4kciB-1mhzD:
0.0		 4kciA-1mhzD:
20.85
4kciB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.39A 4kcjA-1mhzD:
0.0
4kcjB-1mhzD:
0.0		 4kcjA-1mhzD:
20.85
4kcjB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.38A 4kcjA-1mhzD:
0.0
4kcjB-1mhzD:
0.0		 4kcjA-1mhzD:
20.85
4kcjB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.44A 4kckA-1mhzD:
0.0
4kckB-1mhzD:
0.0		 4kckA-1mhzD:
20.85
4kckB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.40A 4kckA-1mhzD:
0.0
4kckB-1mhzD:
0.0		 4kckA-1mhzD:
20.85
4kckB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.36A 4kclA-1mhzD:
0.0
4kclB-1mhzD:
0.0		 4kclA-1mhzD:
20.85
4kclB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.37A 4kclA-1mhzD:
0.0
4kclB-1mhzD:
0.0		 4kclA-1mhzD:
20.85
4kclB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.35A 4kcmA-1mhzD:
0.0
4kcmB-1mhzD:
0.0		 4kcmA-1mhzD:
20.85
4kcmB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.35A 4kcmA-1mhzD:
0.0
4kcmB-1mhzD:
0.0		 4kcmA-1mhzD:
20.85
4kcmB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.38A 4kcnA-1mhzD:
0.0
4kcnB-1mhzD:
0.0		 4kcnA-1mhzD:
20.85
4kcnB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.37A 4kcnA-1mhzD:
0.0
4kcnB-1mhzD:
0.0		 4kcnA-1mhzD:
20.85
4kcnB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.37A 4kcoA-1mhzD:
undetectable
4kcoB-1mhzD:
undetectable		 4kcoA-1mhzD:
20.85
4kcoB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.35A 4kcoA-1mhzD:
undetectable
4kcoB-1mhzD:
undetectable		 4kcoA-1mhzD:
20.85
4kcoB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.35A 4luxA-1mhzD:
undetectable
4luxB-1mhzD:
undetectable		 4luxA-1mhzD:
20.85
4luxB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.40A 4luxA-1mhzD:
0.0
4luxB-1mhzD:
0.0		 4luxA-1mhzD:
20.85
4luxB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA7_A_P2ZA301_1
(MAJOR PRION PROTEIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 8 VAL D 285
LEU D 346
ILE D 426
THR D 449
 None
 0.97A 4ma7A-1mhzD:
undetectable		 4ma7A-1mhzD:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA302_0
(THAUMATIN-1)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		3 / 3 ARG D 463
GLN D 456
GLU D 199
 None
 0.92A 4tvtA-1mhzD:
0.0		 4tvtA-1mhzD:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.35A 4uchA-1mhzD:
undetectable
4uchB-1mhzD:
undetectable		 4uchA-1mhzD:
20.73
4uchB-1mhzD:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 8 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.37A 4uchA-1mhzD:
0.0
4uchB-1mhzD:
0.0		 4uchA-1mhzD:
20.73
4uchB-1mhzD:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.41A 4ugzA-1mhzD:
undetectable
4ugzB-1mhzD:
undetectable		 4ugzA-1mhzD:
20.85
4ugzB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.34A 4uh1A-1mhzD:
undetectable
4uh1B-1mhzD:
undetectable		 4uh1A-1mhzD:
20.85
4uh1B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.36A 4uh1A-1mhzD:
0.0
4uh1B-1mhzD:
0.0		 4uh1A-1mhzD:
20.85
4uh1B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.42A 4uh2A-1mhzD:
0.0
4uh2B-1mhzD:
0.0		 4uh2A-1mhzD:
20.85
4uh2B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.41A 4uh2A-1mhzD:
undetectable
4uh2B-1mhzD:
undetectable		 4uh2A-1mhzD:
20.85
4uh2B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.39A 4uh3A-1mhzD:
undetectable
4uh3B-1mhzD:
undetectable		 4uh3A-1mhzD:
20.85
4uh3B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.36A 4uh4A-1mhzD:
0.0
4uh4B-1mhzD:
0.0		 4uh4A-1mhzD:
20.85
4uh4B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.35A 4uh4A-1mhzD:
0.0
4uh4B-1mhzD:
0.0		 4uh4A-1mhzD:
20.85
4uh4B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.32A 4uh5A-1mhzD:
0.0
4uh5B-1mhzD:
0.0		 4uh5A-1mhzD:
20.77
4uh5B-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.40A 4uh5A-1mhzD:
undetectable
4uh5B-1mhzD:
undetectable		 4uh5A-1mhzD:
20.77
4uh5B-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.34A 4uh6A-1mhzD:
0.0
4uh6B-1mhzD:
0.0		 4uh6A-1mhzD:
20.77
4uh6B-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.43A 4uh6A-1mhzD:
0.0
4uh6B-1mhzD:
0.0		 4uh6A-1mhzD:
20.77
4uh6B-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.35A 4upmA-1mhzD:
undetectable
4upmB-1mhzD:
undetectable		 4upmA-1mhzD:
20.85
4upmB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.36A 4upmA-1mhzD:
0.0
4upmB-1mhzD:
0.0		 4upmA-1mhzD:
20.85
4upmB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.39A 4upnA-1mhzD:
undetectable
4upnB-1mhzD:
undetectable		 4upnA-1mhzD:
20.85
4upnB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.38A 4upnA-1mhzD:
0.0
4upnB-1mhzD:
0.0		 4upnA-1mhzD:
20.85
4upnB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.35A 4upoA-1mhzD:
0.0
4upoB-1mhzD:
0.0		 4upoA-1mhzD:
20.85
4upoB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.35A 4upoA-1mhzD:
0.0
4upoB-1mhzD:
0.0		 4upoA-1mhzD:
20.85
4upoB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.42A 4uppA-1mhzD:
0.0
4uppB-1mhzD:
0.0		 4uppA-1mhzD:
20.85
4uppB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.34A 4v3uA-1mhzD:
0.0
4v3uB-1mhzD:
0.0		 4v3uA-1mhzD:
20.82
4v3uB-1mhzD:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.38A 4v3uA-1mhzD:
undetectable
4v3uB-1mhzD:
undetectable		 4v3uA-1mhzD:
20.82
4v3uB-1mhzD:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.37A 4v3uC-1mhzD:
0.0
4v3uD-1mhzD:
0.0		 4v3uC-1mhzD:
20.82
4v3uD-1mhzD:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.39A 4v3uC-1mhzD:
0.0
4v3uD-1mhzD:
0.0		 4v3uC-1mhzD:
20.82
4v3uD-1mhzD:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.42A 4v3vA-1mhzD:
0.0
4v3vB-1mhzD:
0.0		 4v3vA-1mhzD:
20.85
4v3vB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.39A 4v3vA-1mhzD:
undetectable
4v3vB-1mhzD:
undetectable		 4v3vA-1mhzD:
20.85
4v3vB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3W_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.40A 4v3wA-1mhzD:
0.0
4v3wB-1mhzD:
0.0		 4v3wA-1mhzD:
20.85
4v3wB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.37A 4v3xA-1mhzD:
0.0
4v3xB-1mhzD:
0.0		 4v3xA-1mhzD:
20.85
4v3xB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.37A 4v3xA-1mhzD:
0.0
4v3xB-1mhzD:
0.0		 4v3xA-1mhzD:
20.85
4v3xB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.37A 4v3yA-1mhzD:
undetectable
4v3yB-1mhzD:
undetectable		 4v3yA-1mhzD:
20.85
4v3yB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 8 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.35A 4v3yA-1mhzD:
0.0
4v3yB-1mhzD:
0.0		 4v3yA-1mhzD:
20.85
4v3yB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.36A 4v3zA-1mhzD:
0.0
4v3zB-1mhzD:
0.0		 4v3zA-1mhzD:
20.85
4v3zB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.35A 4v3zA-1mhzD:
0.0
4v3zB-1mhzD:
0.0		 4v3zA-1mhzD:
20.85
4v3zB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.41A 5ad5A-1mhzD:
0.0
5ad5B-1mhzD:
0.0		 5ad5A-1mhzD:
20.85
5ad5B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.44A 5ad7A-1mhzD:
0.0
5ad7B-1mhzD:
0.0		 5ad7A-1mhzD:
20.85
5ad7B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.38A 5adcA-1mhzD:
0.0
5adcB-1mhzD:
0.0		 5adcA-1mhzD:
20.85
5adcB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.34A 5adcA-1mhzD:
0.0
5adcB-1mhzD:
0.0		 5adcA-1mhzD:
20.85
5adcB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.35A 5adfA-1mhzD:
0.0
5adfB-1mhzD:
0.0		 5adfA-1mhzD:
20.77
5adfB-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.33A 5adgA-1mhzD:
undetectable
5adgB-1mhzD:
undetectable		 5adgA-1mhzD:
20.77
5adgB-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.42A 5adgA-1mhzD:
undetectable
5adgB-1mhzD:
undetectable		 5adgA-1mhzD:
20.77
5adgB-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADI_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.42A 5adiA-1mhzD:
0.0
5adiB-1mhzD:
0.0		 5adiA-1mhzD:
20.77
5adiB-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.40A 5agkA-1mhzD:
undetectable
5agkB-1mhzD:
undetectable		 5agkA-1mhzD:
20.85
5agkB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.38A 5agkA-1mhzD:
undetectable
5agkB-1mhzD:
undetectable		 5agkA-1mhzD:
20.85
5agkB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.36A 5aglA-1mhzD:
undetectable
5aglB-1mhzD:
undetectable		 5aglA-1mhzD:
20.85
5aglB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.36A 5aglA-1mhzD:
0.0
5aglB-1mhzD:
0.0		 5aglA-1mhzD:
20.85
5aglB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.34A 5agmA-1mhzD:
undetectable
5agmB-1mhzD:
undetectable		 5agmA-1mhzD:
20.85
5agmB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.31A 5agmA-1mhzD:
0.0
5agmB-1mhzD:
0.0		 5agmA-1mhzD:
20.85
5agmB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.35A 5agnA-1mhzD:
0.0
5agnB-1mhzD:
0.0		 5agnA-1mhzD:
20.85
5agnB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.33A 5agnA-1mhzD:
0.0
5agnB-1mhzD:
0.0		 5agnA-1mhzD:
20.85
5agnB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.37A 5agoA-1mhzD:
undetectable
5agoB-1mhzD:
undetectable		 5agoA-1mhzD:
20.85
5agoB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.37A 5agoA-1mhzD:
undetectable
5agoB-1mhzD:
undetectable		 5agoA-1mhzD:
20.85
5agoB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.43A 5agpA-1mhzD:
0.0
5agpB-1mhzD:
0.0		 5agpA-1mhzD:
20.85
5agpB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.40A 5agpA-1mhzD:
0.0
5agpB-1mhzD:
0.0		 5agpA-1mhzD:
20.85
5agpB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 ILE D 318
LEU D 321
ARG D 330
THR D 269
 None
 0.99A 5b1aN-1mhzD:
0.3
5b1aW-1mhzD:
0.0		 5b1aN-1mhzD:
21.42
5b1aW-1mhzD:
6.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_B_ACTB404_0
(D-ALANINE--D-ALANINE
LIGASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 TYR D 137
GLY D 250
SER D 201
LEU D 204
 None
 1.05A 5bphB-1mhzD:
undetectable		 5bphB-1mhzD:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.45A 5fvpA-1mhzD:
0.0
5fvpB-1mhzD:
0.0		 5fvpA-1mhzD:
20.85
5fvpB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.34A 5fvqA-1mhzD:
0.0
5fvqB-1mhzD:
0.0		 5fvqA-1mhzD:
20.85
5fvqB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.35A 5fvqA-1mhzD:
0.0
5fvqB-1mhzD:
0.0		 5fvqA-1mhzD:
20.85
5fvqB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.33A 5fvrA-1mhzD:
0.0
5fvrB-1mhzD:
0.0		 5fvrA-1mhzD:
20.85
5fvrB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.35A 5fvrA-1mhzD:
0.0
5fvrB-1mhzD:
0.0		 5fvrA-1mhzD:
20.85
5fvrB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.34A 5fvsA-1mhzD:
0.0
5fvsB-1mhzD:
0.0		 5fvsA-1mhzD:
20.85
5fvsB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.36A 5fvsA-1mhzD:
0.0
5fvsB-1mhzD:
0.0		 5fvsA-1mhzD:
20.85
5fvsB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.34A 5fvtA-1mhzD:
0.0
5fvtB-1mhzD:
0.0		 5fvtA-1mhzD:
20.85
5fvtB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.34A 5fvtA-1mhzD:
0.0
5fvtB-1mhzD:
0.0		 5fvtA-1mhzD:
20.85
5fvtB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.30A 5fvuA-1mhzD:
0.0
5fvuB-1mhzD:
0.0		 5fvuA-1mhzD:
20.77
5fvuB-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.38A 5fvuA-1mhzD:
0.0
5fvuB-1mhzD:
0.0		 5fvuA-1mhzD:
20.77
5fvuB-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.32A 5fvvA-1mhzD:
0.0
5fvvB-1mhzD:
0.0		 5fvvA-1mhzD:
20.77
5fvvB-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.37A 5fvvA-1mhzD:
undetectable
5fvvB-1mhzD:
undetectable		 5fvvA-1mhzD:
20.77
5fvvB-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.28A 5fvwA-1mhzD:
undetectable
5fvwB-1mhzD:
undetectable		 5fvwA-1mhzD:
20.77
5fvwB-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.35A 5fvwA-1mhzD:
0.0
5fvwB-1mhzD:
0.0		 5fvwA-1mhzD:
20.77
5fvwB-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.31A 5fvxA-1mhzD:
0.0
5fvxB-1mhzD:
0.0		 5fvxA-1mhzD:
20.77
5fvxB-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.42A 5fw0A-1mhzD:
undetectable
5fw0B-1mhzD:
undetectable		 5fw0A-1mhzD:
20.85
5fw0B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.45A 5fw0A-1mhzD:
undetectable
5fw0B-1mhzD:
undetectable		 5fw0A-1mhzD:
20.85
5fw0B-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.36A 5g0nA-1mhzD:
0.0
5g0nB-1mhzD:
0.0		 5g0nA-1mhzD:
20.85
5g0nB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.36A 5g0nA-1mhzD:
0.0
5g0nB-1mhzD:
0.0		 5g0nA-1mhzD:
20.85
5g0nB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.44A 5g0oA-1mhzD:
0.0
5g0oB-1mhzD:
0.0		 5g0oA-1mhzD:
20.85
5g0oB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.39A 5g0oA-1mhzD:
0.0
5g0oB-1mhzD:
0.0		 5g0oA-1mhzD:
20.85
5g0oB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_2
(TUBULIN BETA-2B
CHAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		3 / 3 THR D 283
PRO D 329
ARG D 330
 None
 0.70A 5nd7B-1mhzD:
undetectable		 5nd7B-1mhzD:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.36A 5unrA-1mhzD:
0.0
5unrB-1mhzD:
0.0		 5unrA-1mhzD:
20.85
5unrB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.40A 5unsA-1mhzD:
0.0
5unsB-1mhzD:
0.0		 5unsA-1mhzD:
20.85
5unsB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.39A 5unsA-1mhzD:
0.0
5unsB-1mhzD:
0.0		 5unsA-1mhzD:
20.85
5unsB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.37A 5untA-1mhzD:
0.0
5untB-1mhzD:
0.0		 5untA-1mhzD:
20.85
5untB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.38A 5untA-1mhzD:
0.0
5untB-1mhzD:
0.0		 5untA-1mhzD:
20.85
5untB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.39A 5unuA-1mhzD:
0.0
5unuB-1mhzD:
0.0		 5unuA-1mhzD:
20.85
5unuB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.44A 5unwA-1mhzD:
0.0
5unwB-1mhzD:
0.0		 5unwA-1mhzD:
20.85
5unwB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.46A 5unxA-1mhzD:
0.0
5unxB-1mhzD:
0.0		 5unxA-1mhzD:
20.85
5unxB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.44A 5unyA-1mhzD:
0.0
5unyB-1mhzD:
0.0		 5unyA-1mhzD:
20.85
5unyB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.34A 5uo1A-1mhzD:
0.0
5uo1B-1mhzD:
0.0		 5uo1A-1mhzD:
20.77
5uo1B-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.37A 5uo1A-1mhzD:
0.0
5uo1B-1mhzD:
0.0		 5uo1A-1mhzD:
20.77
5uo1B-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.38A 5uo2A-1mhzD:
0.0
5uo2B-1mhzD:
0.0		 5uo2A-1mhzD:
20.77
5uo2B-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.40A 5uo2A-1mhzD:
0.0
5uo2B-1mhzD:
0.0		 5uo2A-1mhzD:
20.77
5uo2B-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.36A 5uo3A-1mhzD:
0.0
5uo3B-1mhzD:
0.0		 5uo3A-1mhzD:
20.77
5uo3B-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.33A 5uo4A-1mhzD:
undetectable
5uo4B-1mhzD:
undetectable		 5uo4A-1mhzD:
20.77
5uo4B-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.40A 5uo4A-1mhzD:
0.0
5uo4B-1mhzD:
0.0		 5uo4A-1mhzD:
20.77
5uo4B-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.32A 5uo5A-1mhzD:
undetectable
5uo5B-1mhzD:
undetectable		 5uo5A-1mhzD:
20.77
5uo5B-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.43A 5uo5A-1mhzD:
0.0
5uo5B-1mhzD:
0.0		 5uo5A-1mhzD:
20.77
5uo5B-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO6_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.40A 5uo6A-1mhzD:
0.0
5uo6B-1mhzD:
0.0		 5uo6A-1mhzD:
20.77
5uo6B-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.41A 5uo7A-1mhzD:
0.0
5uo7B-1mhzD:
0.0		 5uo7A-1mhzD:
20.77
5uo7B-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		3 / 3 ASP D 170
ASN D 169
ASP D 164
 None
 0.85A 5vopA-1mhzD:
undetectable		 5vopA-1mhzD:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.42A 5vuiA-1mhzD:
undetectable
5vuiB-1mhzD:
undetectable		 5vuiA-1mhzD:
20.85
5vuiB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.42A 5vulA-1mhzD:
0.0
5vulB-1mhzD:
0.0		 5vulA-1mhzD:
20.85
5vulB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.41A 5vulA-1mhzD:
0.0
5vulB-1mhzD:
0.0		 5vulA-1mhzD:
20.85
5vulB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.38A 5vumA-1mhzD:
undetectable
5vumB-1mhzD:
undetectable		 5vumA-1mhzD:
20.85
5vumB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.40A 5vumA-1mhzD:
undetectable
5vumB-1mhzD:
undetectable		 5vumA-1mhzD:
20.85
5vumB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.36A 5vunA-1mhzD:
0.0
5vunB-1mhzD:
0.0		 5vunA-1mhzD:
20.85
5vunB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.35A 5vunA-1mhzD:
0.0
5vunB-1mhzD:
0.0		 5vunA-1mhzD:
20.85
5vunB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.39A 5vuoA-1mhzD:
0.0
5vuoB-1mhzD:
0.0		 5vuoA-1mhzD:
20.85
5vuoB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.37A 5vuoA-1mhzD:
undetectable
5vuoB-1mhzD:
undetectable		 5vuoA-1mhzD:
20.85
5vuoB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.39A 5vupA-1mhzD:
0.0
5vupB-1mhzD:
0.0		 5vupA-1mhzD:
20.85
5vupB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.40A 5vupA-1mhzD:
0.0
5vupB-1mhzD:
0.0		 5vupA-1mhzD:
20.85
5vupB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.43A 5vuqA-1mhzD:
0.0
5vuqB-1mhzD:
0.0		 5vuqA-1mhzD:
20.85
5vuqB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.42A 5vuqA-1mhzD:
undetectable
5vuqB-1mhzD:
undetectable		 5vuqA-1mhzD:
20.85
5vuqB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.39A 5vutA-1mhzD:
0.0
5vutB-1mhzD:
0.0		 5vutA-1mhzD:
20.85
5vutB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.36A 5vutA-1mhzD:
0.0
5vutB-1mhzD:
0.0		 5vutA-1mhzD:
20.85
5vutB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.41A 5vuuA-1mhzD:
0.0
5vuuB-1mhzD:
0.0		 5vuuA-1mhzD:
20.85
5vuuB-1mhzD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.37A 5vuvA-1mhzD:
undetectable
5vuvB-1mhzD:
undetectable		 5vuvA-1mhzD:
20.77
5vuvB-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.37A 5vuvA-1mhzD:
undetectable
5vuvB-1mhzD:
undetectable		 5vuvA-1mhzD:
20.77
5vuvB-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.35A 5vuwA-1mhzD:
undetectable
5vuwB-1mhzD:
undetectable		 5vuwA-1mhzD:
20.77
5vuwB-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.40A 5vuwA-1mhzD:
0.0
5vuwB-1mhzD:
0.0		 5vuwA-1mhzD:
20.77
5vuwB-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.32A 5vuxA-1mhzD:
undetectable
5vuxB-1mhzD:
undetectable		 5vuxA-1mhzD:
20.77
5vuxB-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.41A 5vuyA-1mhzD:
0.0
5vuyB-1mhzD:
0.0		 5vuyA-1mhzD:
20.77
5vuyB-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.42A 5vuyA-1mhzD:
undetectable
5vuyB-1mhzD:
undetectable		 5vuyA-1mhzD:
20.77
5vuyB-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.38A 5vuzA-1mhzD:
undetectable
5vuzB-1mhzD:
undetectable		 5vuzA-1mhzD:
20.77
5vuzB-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.38A 5vv0A-1mhzD:
0.0
5vv0B-1mhzD:
0.0		 5vv0A-1mhzD:
20.77
5vv0B-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.41A 5vv1A-1mhzD:
0.0
5vv1B-1mhzD:
0.0		 5vv1A-1mhzD:
20.77
5vv1B-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.36A 5vv2A-1mhzD:
undetectable
5vv2B-1mhzD:
undetectable		 5vv2A-1mhzD:
20.77
5vv2B-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.43A 5vv2A-1mhzD:
0.0
5vv2B-1mhzD:
0.0		 5vv2A-1mhzD:
20.77
5vv2B-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.42A 5vv3A-1mhzD:
undetectable
5vv3B-1mhzD:
undetectable		 5vv3A-1mhzD:
20.77
5vv3B-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.48A 5vv3A-1mhzD:
undetectable
5vv3B-1mhzD:
undetectable		 5vv3A-1mhzD:
20.77
5vv3B-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.43A 5vv4A-1mhzD:
undetectable
5vv4B-1mhzD:
undetectable		 5vv4A-1mhzD:
20.77
5vv4B-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.37A 5vv5A-1mhzD:
undetectable
5vv5B-1mhzD:
undetectable		 5vv5A-1mhzD:
20.77
5vv5B-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.43A 5vv5A-1mhzD:
0.0
5vv5B-1mhzD:
0.0		 5vv5A-1mhzD:
20.77
5vv5B-1mhzD:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.34A 6aurA-1mhzD:
0.0
6aurB-1mhzD:
0.0		 6aurA-1mhzD:
9.02
6aurB-1mhzD:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.34A 6aurA-1mhzD:
0.0
6aurB-1mhzD:
0.0		 6aurA-1mhzD:
9.02
6aurB-1mhzD:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.35A 6ausA-1mhzD:
undetectable
6ausB-1mhzD:
undetectable		 6ausA-1mhzD:
9.02
6ausB-1mhzD:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.35A 6ausA-1mhzD:
0.0
6ausB-1mhzD:
0.0		 6ausA-1mhzD:
9.02
6ausB-1mhzD:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.35A 6autA-1mhzD:
undetectable
6autB-1mhzD:
undetectable		 6autA-1mhzD:
9.02
6autB-1mhzD:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.36A 6autA-1mhzD:
0.0
6autB-1mhzD:
0.0		 6autA-1mhzD:
9.02
6autB-1mhzD:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.41A 6auuA-1mhzD:
0.0
6auuB-1mhzD:
0.0		 6auuA-1mhzD:
9.02
6auuB-1mhzD:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.40A 6auuA-1mhzD:
0.0
6auuB-1mhzD:
0.0		 6auuA-1mhzD:
9.02
6auuB-1mhzD:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.33A 6auvA-1mhzD:
0.0
6auvB-1mhzD:
0.0		 6auvA-1mhzD:
9.02
6auvB-1mhzD:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.33A 6auvA-1mhzD:
0.0
6auvB-1mhzD:
0.0		 6auvA-1mhzD:
9.02
6auvB-1mhzD:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.42A 6auwA-1mhzD:
0.0
6auwB-1mhzD:
0.0		 6auwA-1mhzD:
9.02
6auwB-1mhzD:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.38A 6auwA-1mhzD:
0.0
6auwB-1mhzD:
0.0		 6auwA-1mhzD:
9.02
6auwB-1mhzD:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.46A 6auxA-1mhzD:
0.0
6auxB-1mhzD:
0.0		 6auxA-1mhzD:
9.02
6auxB-1mhzD:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.45A 6auxA-1mhzD:
0.0
6auxB-1mhzD:
0.0		 6auxA-1mhzD:
9.02
6auxB-1mhzD:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.33A 6auyA-1mhzD:
undetectable
6auyB-1mhzD:
undetectable		 6auyA-1mhzD:
9.79
6auyB-1mhzD:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.41A 6auyA-1mhzD:
0.0
6auyB-1mhzD:
0.0		 6auyA-1mhzD:
9.79
6auyB-1mhzD:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.33A 6auzA-1mhzD:
undetectable
6auzB-1mhzD:
undetectable		 6auzA-1mhzD:
9.79
6auzB-1mhzD:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.39A 6auzA-1mhzD:
0.0
6auzB-1mhzD:
0.0		 6auzA-1mhzD:
9.79
6auzB-1mhzD:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.33A 6av0A-1mhzD:
0.0
6av0B-1mhzD:
0.0		 6av0A-1mhzD:
9.79
6av0B-1mhzD:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.38A 6av0A-1mhzD:
0.0
6av0B-1mhzD:
0.0		 6av0A-1mhzD:
9.79
6av0B-1mhzD:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.29A 6av1A-1mhzD:
0.0
6av1B-1mhzD:
0.0		 6av1A-1mhzD:
9.79
6av1B-1mhzD:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.42A 6av1A-1mhzD:
0.0
6av1B-1mhzD:
0.0		 6av1A-1mhzD:
9.79
6av1B-1mhzD:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.39A 6av2A-1mhzD:
0.0
6av2B-1mhzD:
0.0		 6av2A-1mhzD:
9.79
6av2B-1mhzD:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.47A 6av2A-1mhzD:
0.0
6av2B-1mhzD:
0.0		 6av2A-1mhzD:
9.79
6av2B-1mhzD:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.32A 6av3A-1mhzD:
undetectable
6av3B-1mhzD:
undetectable		 6av3A-1mhzD:
9.79
6av3B-1mhzD:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.36A 6av3A-1mhzD:
0.0
6av3B-1mhzD:
0.0		 6av3A-1mhzD:
9.79
6av3B-1mhzD:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.31A 6av4A-1mhzD:
undetectable
6av4B-1mhzD:
undetectable		 6av4A-1mhzD:
9.79
6av4B-1mhzD:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.38A 6av4A-1mhzD:
0.0
6av4B-1mhzD:
0.0		 6av4A-1mhzD:
9.79
6av4B-1mhzD:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.31A 6av5A-1mhzD:
0.0
6av5B-1mhzD:
0.0		 6av5A-1mhzD:
9.79
6av5B-1mhzD:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.37A 6av5A-1mhzD:
0.0
6av5B-1mhzD:
0.0		 6av5A-1mhzD:
9.79
6av5B-1mhzD:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.34A 6cicA-1mhzD:
0.0
6cicB-1mhzD:
0.0		 6cicA-1mhzD:
9.79
6cicB-1mhzD:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_B_H4BB802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.33A 6cicA-1mhzD:
0.0
6cicB-1mhzD:
0.0		 6cicA-1mhzD:
9.79
6cicB-1mhzD:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 VAL D  28
TRP D  31
PHE D  35
GLU D 132
 None
 1.31A 6cidA-1mhzD:
undetectable
6cidB-1mhzD:
undetectable		 6cidA-1mhzD:
9.79
6cidB-1mhzD:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_B_H4BB803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 7 PHE D  35
GLU D 132
VAL D  28
TRP D  31
 None
 1.36A 6cidA-1mhzD:
0.0
6cidB-1mhzD:
0.0		 6cidA-1mhzD:
9.79
6cidB-1mhzD:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 GLN D 150
VAL D 239
GLU D 209
ALA D 120
 None
None
FE  D 802 ( 3.2A)
None
 1.12A 6djzB-1mhzD:
undetectable		 6djzB-1mhzD:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_D_ACTD404_0
(L-LYSINE
3-HYDROXYLASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 GLN D 369
GLU D 367
TRP D 371
ALA D 370
 None
 1.35A 6f6jC-1mhzD:
0.0
6f6jD-1mhzD:
0.0		 6f6jC-1mhzD:
20.56
6f6jD-1mhzD:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		4 / 6 ILE D 318
LEU D 321
ARG D 330
THR D 269
 None
 1.10A 6nmfN-1mhzD:
0.5
6nmfW-1mhzD:
undetectable		 6nmfN-1mhzD:
21.42
6nmfW-1mhzD:
6.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_H_FFOH403_0
(THYMIDYLATE SYNTHASE)		 1mhz METHANE
MONOOXYGENASE
HYDROXYLASE
(Methylosinus
trichosporium) 		5 / 12 TYR D 281
LEU D 346
LEU D 356
GLY D 178
MET D 353
 None
 1.28A 6r2eH-1mhzD:
0.0		 6r2eH-1mhzD:
20.54