SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mi1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C3S_A_SHHA952_1
(HDLP (HISTONE
DEACETYLASE-LIKE
PROTEIN))		 1mi1 NEUROBEACHIN
(Homo
sapiens) 		5 / 11 PRO A2311
TYR A2429
PHE A2330
ASP A2332
LEU A2333
 None
 1.46A 1c3sA-1mi1A:
undetectable		 1c3sA-1mi1A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_A_EAAA223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 1mi1 NEUROBEACHIN
(Homo
sapiens) 		4 / 8 PHE A2397
GLY A2395
VAL A2186
PHE A2389
 None
 1.02A 1gsfA-1mi1A:
0.0		 1gsfA-1mi1A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_B_EAAB223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 1mi1 NEUROBEACHIN
(Homo
sapiens) 		4 / 8 PHE A2397
GLY A2395
VAL A2186
PHE A2389
 None
 1.02A 1gsfB-1mi1A:
0.0		 1gsfB-1mi1A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_C_EAAC223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 1mi1 NEUROBEACHIN
(Homo
sapiens) 		4 / 8 PHE A2397
GLY A2395
VAL A2186
PHE A2389
 None
 1.02A 1gsfC-1mi1A:
0.0		 1gsfC-1mi1A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_D_EAAD223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 1mi1 NEUROBEACHIN
(Homo
sapiens) 		4 / 8 PHE A2397
GLY A2395
VAL A2186
PHE A2389
 None
 1.02A 1gsfD-1mi1A:
0.0		 1gsfD-1mi1A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M2Z_D_DEXD401_1
(GLUCOCORTICOID
RECEPTOR)		 1mi1 NEUROBEACHIN
(Homo
sapiens) 		5 / 12 ASN A2393
GLY A2395
THR A2403
PHE A2389
LEU A2390
 None
 1.28A 1m2zD-1mi1A:
undetectable		 1m2zD-1mi1A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 1mi1 NEUROBEACHIN
(Homo
sapiens) 		4 / 8 LYS A2239
VAL A2240
THR A2164
LEU A2161
 None
 0.89A 1z2bB-1mi1A:
undetectable		 1z2bB-1mi1A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5P_A_TACA7101_1
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 1mi1 NEUROBEACHIN
(Homo
sapiens) 		5 / 12 ASN A2366
TYR A2363
ILE A2491
TYR A2513
TYR A2348
 None
 1.04A 3q5pA-1mi1A:
0.0		 3q5pA-1mi1A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UR0_B_SVRB516_1
(RNA-DEPENDENT RNA
POLYMERASE)		 1mi1 NEUROBEACHIN
(Homo
sapiens) 		4 / 7 PRO A2336
GLY A2338
ALA A2339
ALA A2349
 None
 0.85A 3ur0B-1mi1A:
0.0		 3ur0B-1mi1A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 1mi1 NEUROBEACHIN
(Homo
sapiens) 		5 / 12 PHE A2388
PHE A2385
PRO A2384
VAL A2172
ALA A2152
 None
 1.32A 4a84A-1mi1A:
0.0		 4a84A-1mi1A:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 1mi1 NEUROBEACHIN
(Homo
sapiens) 		4 / 7 PHE A2231
LEU A2144
VAL A2205
VAL A2219
 None
 1.01A 4cp4A-1mi1A:
0.0		 4cp4A-1mi1A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_B_LNLB701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1mi1 NEUROBEACHIN
(Homo
sapiens) 		4 / 7 VAL A2237
VAL A2241
LEU A2244
VAL A2247
 None
 1.02A 4e1gB-1mi1A:
undetectable		 4e1gB-1mi1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_1
(ADENOSINE KINASE)		 1mi1 NEUROBEACHIN
(Homo
sapiens) 		5 / 12 GLY A2195
GLY A2192
PHE A2170
PHE A2229
ALA A2152
 None
 1.09A 4ubeA-1mi1A:
undetectable		 4ubeA-1mi1A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_B_SAMB303_0
(CATECHOL
O-METHYLTRANSFERASE)		 1mi1 NEUROBEACHIN
(Homo
sapiens) 		5 / 12 TYR A2307
SER A2370
ILE A2151
ASN A2302
GLN A2149
 None
 1.46A 4xueB-1mi1A:
undetectable		 4xueB-1mi1A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_2
(ADENOSINE KINASE)		 1mi1 NEUROBEACHIN
(Homo
sapiens) 		4 / 4 ASN A2286
LEU A2475
SER A2477
LEU A2314
 None
 1.39A 5kb5A-1mi1A:
undetectable		 5kb5A-1mi1A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 1mi1 NEUROBEACHIN
(Homo
sapiens) 		5 / 12 GLY A2298
LEU A2293
VAL A2249
LEU A2269
ALA A2264
 None
 0.93A 5kpcA-1mi1A:
undetectable		 5kpcA-1mi1A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWY_A_YNUA1101_0
(MINERALOCORTICOID
RECEPTOR)		 1mi1 NEUROBEACHIN
(Homo
sapiens) 		5 / 12 LEU A2290
LEU A2293
ASN A2294
ALA A2297
LEU A2546
 None
 0.53A 5mwyA-1mi1A:
undetectable		 5mwyA-1mi1A:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_C_GLYC713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 1mi1 NEUROBEACHIN
(Homo
sapiens) 		3 / 3 GLN A2149
TYR A2210
ASN A2230
 None
 1.01A 6dwdC-1mi1A:
0.0		 6dwdC-1mi1A:
22.40