SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mi8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_1
(FTSJ)		 1mi8 DNAB INTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 ASP A  21
ASP A  24
ASP A   5
 None
 0.74A 1eizA-1mi8A:
undetectable		 1eizA-1mi8A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_1
(FTSJ)		 1mi8 DNAB INTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 ASP A  21
ASP A  24
ASP A   5
 None
 0.71A 1ej0A-1mi8A:
undetectable		 1ej0A-1mi8A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_D_RBFD504_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1mi8 DNAB INTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 LEU A  87
HIS A  73
TRP A  81
GLY A  80
ILE A  93
 None
 1.19A 1kyvC-1mi8A:
undetectable
1kyvD-1mi8A:
undetectable		 1kyvC-1mi8A:
21.02
1kyvD-1mi8A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_E_RBFE505_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1mi8 DNAB INTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 LEU A  87
HIS A  73
TRP A  81
GLY A  80
ILE A  93
 None
 1.19A 1kyvD-1mi8A:
undetectable
1kyvE-1mi8A:
undetectable		 1kyvD-1mi8A:
21.02
1kyvE-1mi8A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_0
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1mi8 DNAB INTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 SER A   3
PHE A  75
PHE A 145
ILE A 150
LEU A  23
 None
 1.45A 3aocC-1mi8A:
undetectable		 3aocC-1mi8A:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 1mi8 DNAB INTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 ASP A  21
ASP A  24
ASP A   5
 None
 0.77A 3douA-1mi8A:
undetectable		 3douA-1mi8A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EIG_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 1mi8 DNAB INTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 ILE A 151
ALA A 147
LEU A 137
GLU A  41
PRO A 140
 None
 1.17A 3eigA-1mi8A:
undetectable		 3eigA-1mi8A:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_1
(PROTEASE)		 1mi8 DNAB INTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 8 LEU A 137
ASP A 136
GLY A  -1
ALA A   1
ILE A  67
 None
 1.17A 3ekpA-1mi8A:
undetectable		 3ekpA-1mi8A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_A_NCAA300_0
(PROTOGLOBIN)		 1mi8 DNAB INTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 7 VAL A  48
PHE A  28
PHE A 145
ILE A   2
 None
 0.90A 3zjqA-1mi8A:
undetectable		 3zjqA-1mi8A:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_B_NCAB300_0
(PROTOGLOBIN)		 1mi8 DNAB INTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 7 VAL A  48
PHE A  28
PHE A 145
ILE A   2
 None
 0.94A 3zjqB-1mi8A:
undetectable		 3zjqB-1mi8A:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H8T_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 1mi8 DNAB INTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 PHE A  75
LEU A  84
ALA A  69
SER A   6
LEU A  95
 None
 1.16A 5h8tA-1mi8A:
undetectable		 5h8tA-1mi8A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUM_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 1mi8 DNAB INTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 8 ILE A 123
LEU A  87
ILE A  93
ILE A 150
SER A   3
 None
 1.50A 5numA-1mi8A:
undetectable		 5numA-1mi8A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLP_A_GAWA1501_0
(SUBSTANCE-P
RECEPTOR,SUBSTANCE-P
RECEPTOR)		 1mi8 DNAB INTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 ILE A  58
ILE A 126
THR A  61
PHE A  75
PRO A  96
 None
 1.05A 6hlpA-1mi8A:
undetectable		 6hlpA-1mi8A:
15.97