SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mim'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOJ_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1mim CHIMERIC SDZ CHI621
(Homo
sapiens) 		4 / 5 LEU L 176
GLY L 125
PRO L 117
VAL L 129
 None
 0.92A 2aojA-1mimL:
undetectable		 2aojA-1mimL:
15.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OMB_D_IPHD2002_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 1mim CHIMERIC SDZ CHI621
(Homo
sapiens) 		4 / 7 PRO L  43
TYR L  86
HIS L  88
TYR L  35
 None
 1.24A 2ombC-1mimL:
17.3
2ombD-1mimL:
20.1		 2ombC-1mimL:
42.98
2ombD-1mimL:
42.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TX2_A_BEZA251_0
(PROBABLE
6-PHOSPHOGLUCONOLACT
ONASE)		 1mim CHIMERIC SDZ CHI621
(Homo
sapiens) 		4 / 7 LYS L  44
ARG L  45
ALA L  54
TRP L  46
 None
 1.40A 3tx2A-1mimL:
undetectable		 3tx2A-1mimL:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA302_0
(THAUMATIN-1)		 1mim CHIMERIC SDZ CHI621
(Homo
sapiens) 		3 / 3 ARG L 139
GLN L 163
GLU L 162
 None
 0.93A 4tvtA-1mimL:
0.5		 4tvtA-1mimL:
19.00