SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1miq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHV_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		5 / 8 GLY A 216
GLY A 125
PHE A  33
LEU A 126
GLY A  36
 None
 1.27A 1jhvA-1miqA:
undetectable		 1jhvA-1miqA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHV_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		5 / 8 GLY A 216
GLY A 125
PHE A  33
LEU A 126
GLY A 127
 None
 1.44A 1jhvA-1miqA:
undetectable		 1jhvA-1miqA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_2
(DNA GYRASE SUBUNIT B)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		3 / 3 ASP A 121
PHE A  16
VAL A 118
 None
 0.59A 1kijB-1miqA:
0.0		 1kijB-1miqA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L4N_A_NIOA991_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		5 / 9 GLY A 216
GLY A 125
PHE A  33
LEU A 126
GLY A  36
 None
 1.31A 1l4nA-1miqA:
undetectable		 1l4nA-1miqA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_A_FLPA1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		5 / 12 LEU A 124
TYR A 100
GLY A 127
ALA A  38
SER A  37
 None
 1.09A 2aylA-1miqA:
undetectable		 2aylA-1miqA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		4 / 7 LEU A 126
PHE A 154
LEU A 168
PHE A  83
 None
 1.04A 2eimP-1miqA:
undetectable
2eimW-1miqA:
undetectable		 2eimP-1miqA:
20.42
2eimW-1miqA:
9.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1122_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		4 / 7 SER A  44
LYS A  46
SER A  87
SER A  60
 None
 1.10A 2j9cA-1miqA:
0.0
2j9cB-1miqA:
0.0
2j9cC-1miqA:
0.0		 2j9cA-1miqA:
16.80
2j9cB-1miqA:
16.80
2j9cC-1miqA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1122_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		4 / 7 SER A  87
SER A  60
SER A  44
LYS A  46
 None
 1.14A 2j9cA-1miqA:
0.0
2j9cB-1miqA:
0.0
2j9cC-1miqA:
0.0		 2j9cA-1miqA:
16.80
2j9cB-1miqA:
16.80
2j9cC-1miqA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		4 / 8 ASP A 107
SER A  50
SER A 116
ASP A 110
 None
 1.20A 2obvA-1miqA:
undetectable		 2obvA-1miqA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P02_A_SAMA2_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-2)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		4 / 8 ASP A 107
SER A  50
SER A 116
ASP A 110
 None
 1.15A 2p02A-1miqA:
undetectable		 2p02A-1miqA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_3
(PROTEASE RETROPEPSIN)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		5 / 12 ASP A  34
GLY A  36
ASN A  39
ILE A  75
ILE A 123
 None
 0.82A 2q64B-1miqA:
6.9		 2q64B-1miqA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		5 / 12 ASP A  34
GLY A  36
ASN A  39
ILE A  75
ILE A 123
 None
 0.78A 2qakA-1miqA:
7.2		 2qakA-1miqA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1162_1
(ALLERGEN ARG R 1)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		4 / 4 GLU A 175
ASP A 150
HIS A  78
GLU A 174
 None
 1.34A 2x45A-1miqA:
0.0		 2x45A-1miqA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1162_1
(ALLERGEN ARG R 1)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		3 / 3 GLU A 175
HIS A  78
GLU A 174
 None
 0.56A 2x45B-1miqA:
0.0		 2x45B-1miqA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1162_1
(ALLERGEN ARG R 1)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		3 / 3 GLU A 175
HIS A  78
GLU A 174
 None
 0.60A 2x45C-1miqA:
0.0		 2x45C-1miqA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_B_ACRB820_1
(ALPHA-AMYLASE, SUSG)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		4 / 7 TYR A 121
GLU A   2
LEU A 122
ASN A 228
 None
 1.29A 3k8mB-1miqA:
undetectable		 3k8mB-1miqA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_A_GJZA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		4 / 6 LEU A 227
PHE A 231
ILE A 287
THR A 219
 None
 0.95A 3mdrA-1miqA:
0.0		 3mdrA-1miqA:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_2
(CANDIDAPEPSIN-2)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		4 / 6 SER A  37
ILE A  75
TYR A  77
ASP A 121
 None
 1.06A 3q70A-1miqA:
9.4		 3q70A-1miqA:
27.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_C_ACTC502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		3 / 3 PRO A 223
ASP A 293
GLU A 225
 None
 0.88A 3v4tC-1miqA:
0.0		 3v4tC-1miqA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA304_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		3 / 3 ARG A  87
HIS A 164
TYR A  89
 None
 1.24A 4fu8A-1miqA:
1.4		 4fu8A-1miqA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA312_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		3 / 3 ARG A  87
HIS A 164
TYR A  89
 None
 1.31A 4fu9A-1miqA:
undetectable		 4fu9A-1miqA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		4 / 6 TRP A 193
ILE A 195
VAL A 312
ASP A 316
 None
 0.99A 4iaqA-1miqA:
undetectable		 4iaqA-1miqA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		4 / 6 TRP A 193
ILE A 195
VAL A 312
SER A 261
 None
 0.99A 4iaqA-1miqA:
undetectable		 4iaqA-1miqA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		4 / 8 ASP A 107
SER A  50
SER A 116
ASP A 110
 None
 1.19A 4kttA-1miqA:
undetectable		 4kttA-1miqA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		4 / 8 ASP A 107
SER A  50
SER A 116
ASP A 110
 None
 1.12A 4kttC-1miqA:
undetectable		 4kttC-1miqA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		4 / 8 ASP A 107
SER A  50
SER A 116
ASP A 110
 None
 1.16A 4ndnA-1miqA:
undetectable		 4ndnA-1miqA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLA_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		4 / 5 LYS A 308
LEU A 268
GLU A 269
TYR A 272
 None
 1.47A 4olaA-1miqA:
0.0		 4olaA-1miqA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLB_A_TRPA902_0
(PROTEIN ARGONAUTE-2)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		4 / 5 LYS A 308
LEU A 268
GLU A 269
TYR A 272
 None
 1.38A 4olbA-1miqA:
undetectable		 4olbA-1miqA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_B_ML1B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1miq PLASMEPSIN
(Plasmodium
vivax) 		5 / 11 GLY A 216
MET A 306
ILE A 300
PHE A 313
PHE A 154
 None
 1.10A 4qoiA-1miqA:
undetectable
4qoiB-1miqA:
undetectable		 4qoiA-1miqA:
20.11
4qoiB-1miqA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_ADNA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		4 / 8 ASP A 107
SER A  50
SER A 116
ASP A 110
 None
 1.17A 5a1iA-1miqA:
undetectable		 5a1iA-1miqA:
22.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DZK_3_BEZ3801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		4 / 4 LEU A  40
ILE A 103
GLY A 125
ILE A  75
 None
 0.78A 5dzk3-1miqA:
undetectable
5dzkm-1miqA:
undetectable		 5dzk3-1miqA:
33.33
5dzkm-1miqA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_W_BEZW801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		4 / 5 ILE A 103
GLY A 125
ILE A  75
LEU A  40
 None
 0.79A 5dzkB-1miqA:
undetectable
5dzkI-1miqA:
undetectable
5dzkW-1miqA:
undetectable		 5dzkB-1miqA:
18.98
5dzkI-1miqA:
19.52
5dzkW-1miqA:
33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_X_BEZX801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		4 / 5 ILE A 103
GLY A 125
ILE A  75
LEU A  40
 None
 0.82A 5dzki-1miqA:
undetectable
5dzkj-1miqA:
undetectable
5dzkx-1miqA:
undetectable		 5dzki-1miqA:
19.52
5dzkj-1miqA:
19.52
5dzkx-1miqA:
33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_A_TLFA300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		5 / 12 PHE A 259
PHE A 226
VAL A 211
PHE A 299
HIS A 200
 None
 1.18A 6ap6A-1miqA:
undetectable		 6ap6A-1miqA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_B_TLFB300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		5 / 12 PHE A 259
PHE A 226
VAL A 211
PHE A 299
HIS A 200
 None
 1.18A 6ap6B-1miqA:
undetectable		 6ap6B-1miqA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		4 / 8 ASP A 107
SER A  50
SER A 116
ASP A 110
 None
 1.14A 6fbnB-1miqA:
undetectable		 6fbnB-1miqA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		4 / 8 ASP A 107
SER A  50
SER A 116
ASP A 110
 None
 1.19A 6fboA-1miqA:
undetectable		 6fboA-1miqA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCB_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		4 / 8 ASP A 107
SER A  50
SER A 116
ASP A 110
 None
 1.08A 6fcbA-1miqA:
undetectable		 6fcbA-1miqA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCD_A_ADNA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1miq PLASMEPSIN
(Plasmodium
vivax) 		4 / 8 ASP A 107
SER A  50
SER A 116
ASP A 110
 None
 1.17A 6fcdA-1miqA:
undetectable		 6fcdA-1miqA:
14.55