SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mir'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_B_ADNB550_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 1mir PROCATHEPSIN B
(Rattus
norvegicus) 		5 / 11 GLY A  27
GLY A  73
ASP A  22
GLY A  24
LEU A  41
 None
 1.12A 1jg3B-1mirA:
undetectable		 1jg3B-1mirA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1STF_E_CCSE25_0
(PAPAIN
STEFIN B (CYSTATIN
B))		 1mir PROCATHEPSIN B
(Rattus
norvegicus) 		7 / 10 GLN A  23
GLY A  27
SER A  28
TRP A  30
PHE A  32
HIS A 199
ALA A 200
 None
 0.28A 1stfE-1mirA:
25.2
1stfI-1mirA:
undetectable		 1stfE-1mirA:
26.45
1stfI-1mirA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_A_SAMA501_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 1mir PROCATHEPSIN B
(Rattus
norvegicus) 		5 / 12 GLY A  33
SER A 220
VAL A 247
ALA A  79
ALA A  34
 None
 1.47A 2avdA-1mirA:
undetectable		 2avdA-1mirA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P16_A_GG2A298_1
(COAGULATION FACTOR X
(EC 3.4.21.6)
(STUART FACTOR)
(STUART-PROWER
FACTOR))		 1mir PROCATHEPSIN B
(Rattus
norvegicus) 		5 / 12 VAL A  45
TRP A  30
GLY A  70
GLY A  68
TYR A  75
 None
 1.12A 2p16A-1mirA:
undetectable		 2p16A-1mirA:
21.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AI8_A_HNQA255_1
(CATHEPSIN B)		 1mir PROCATHEPSIN B
(Rattus
norvegicus) 		4 / 7 GLN A  23
GLY A  27
HIS A 199
TRP A 221
 None
 0.46A 3ai8A-1mirA:
39.8		 3ai8A-1mirA:
75.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_B_ACTB1358_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 1mir PROCATHEPSIN B
(Rattus
norvegicus) 		4 / 7 PRO A 106
ILE A 105
GLY A 123
SER A  25
 None
 0.94A 4a3uB-1mirA:
undetectable		 4a3uB-1mirA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7H_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 1mir PROCATHEPSIN B
(Rattus
norvegicus) 		3 / 3 ARG A  49
THR A 253
TRP A 257
 None
 1.24A 4d7hA-1mirA:
undetectable		 4d7hA-1mirA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA8_C_Z80C301_1
(MAJOR PRION PROTEIN)		 1mir PROCATHEPSIN B
(Rattus
norvegicus) 		4 / 5 GLY A 193
ILE A  17
LYS A  19
GLN A  20
 None
 1.05A 4ma8C-1mirA:
0.0		 4ma8C-1mirA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UG5_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 1mir PROCATHEPSIN B
(Rattus
norvegicus) 		3 / 3 ARG A  49
THR A 253
TRP A 257
 None
 1.27A 4ug5A-1mirA:
undetectable		 4ug5A-1mirA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGL_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 1mir PROCATHEPSIN B
(Rattus
norvegicus) 		3 / 3 ARG A  49
THR A 253
TRP A 257
 None
 1.24A 4uglA-1mirA:
0.0		 4uglA-1mirA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6C_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 1mir PROCATHEPSIN B
(Rattus
norvegicus) 		3 / 3 ARG A  49
THR A 253
TRP A 257
 None
 1.25A 5g6cA-1mirA:
0.0		 5g6cA-1mirA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_2
(-)		 1mir PROCATHEPSIN B
(Rattus
norvegicus) 		4 / 8 VAL A  33
TYR A  37
HIS A 111
ASN A  29
 None
 1.32A 6gneB-1mirA:
undetectable		 6gneB-1mirA:
21.87