SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1miu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_A_BEZA1162_0
(PEROXIREDOXIN 5)		 1miu BREAST CANCER TYPE 2
SUSCEPTIBILITY
PROTEIN
(Mus
musculus) 		5 / 10 THR A2528
PRO A2529
GLY A2530
LEU A2575
GLY A2429
 None
 1.21A 1h4oA-1miuA:
undetectable
1h4oB-1miuA:
undetectable		 1h4oA-1miuA:
13.34
1h4oB-1miuA:
13.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)		 1miu BREAST CANCER TYPE 2
SUSCEPTIBILITY
PROTEIN
(Mus
musculus) 		4 / 8 THR A2528
PRO A2529
GLY A2530
LEU A2575
 None
 0.60A 1h4oG-1miuA:
undetectable		 1h4oG-1miuA:
13.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_1
(TRANSTHYRETIN)		 1miu BREAST CANCER TYPE 2
SUSCEPTIBILITY
PROTEIN
(Mus
musculus) 		4 / 6 LEU A2906
ALA A2948
LEU A2946
SER A2933
 None
 1.04A 1ictB-1miuA:
undetectable		 1ictB-1miuA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_C_DESC129_1
(TRANSTHYRETIN)		 1miu BREAST CANCER TYPE 2
SUSCEPTIBILITY
PROTEIN
(Mus
musculus) 		4 / 6 LEU A2906
ALA A2948
LEU A2946
SER A2933
 None
 0.95A 1tz8C-1miuA:
undetectable
1tz8D-1miuA:
undetectable		 1tz8C-1miuA:
10.68
1tz8D-1miuA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_C_ADNC903_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 1miu BREAST CANCER TYPE 2
SUSCEPTIBILITY
PROTEIN
(Mus
musculus) 		5 / 12 ILE A2672
THR A2643
ALA A2648
VAL A2661
SER A2475
 None
 1.16A 2gl0A-1miuA:
undetectable
2gl0C-1miuA:
undetectable		 2gl0A-1miuA:
12.02
2gl0C-1miuA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_B_BEZB1162_0
(PEROXIREDOXIN-5)		 1miu BREAST CANCER TYPE 2
SUSCEPTIBILITY
PROTEIN
(Mus
musculus) 		4 / 7 THR A2528
PRO A2529
GLY A2530
LEU A2575
 None
 0.67A 2vl2B-1miuA:
undetectable		 2vl2B-1miuA:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA2_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 1miu BREAST CANCER TYPE 2
SUSCEPTIBILITY
PROTEIN
(Mus
musculus) 		3 / 3 LYS A3002
LYS A3033
VAL A3000
 None
 0.98A 3brfA-1miuA:
0.0		 3brfA-1miuA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_A_1FLA502_1
(TRANSTHYRETIN)		 1miu BREAST CANCER TYPE 2
SUSCEPTIBILITY
PROTEIN
(Mus
musculus) 		4 / 7 LEU A2906
ALA A2948
LEU A2946
SER A2933
 None
 0.96A 3d2tA-1miuA:
undetectable		 3d2tA-1miuA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_A_THHA401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 1miu BREAST CANCER TYPE 2
SUSCEPTIBILITY
PROTEIN
(Mus
musculus) 		6 / 12 LEU A2729
LEU A2724
ASN A2735
VAL A2736
PRO A2656
PRO A2655
 None
 1.44A 3dcjA-1miuA:
undetectable
3dcjB-1miuA:
undetectable		 3dcjA-1miuA:
14.66
3dcjB-1miuA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QF1_A_PZEA6951_1
(LACTOPEROXIDASE)		 1miu BREAST CANCER TYPE 2
SUSCEPTIBILITY
PROTEIN
(Mus
musculus) 		3 / 3 HIS A2544
ARG A2580
GLU A2584
 None
 0.98A 3qf1A-1miuA:
0.0		 3qf1A-1miuA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4APJ_A_ACTA1635_0
(ANGIOTENSIN-CONVERTI
NG ENZYME
BRADYKININ-POTENTIAT
ING PEPTIDE B)		 1miu BREAST CANCER TYPE 2
SUSCEPTIBILITY
PROTEIN
(Mus
musculus) 		4 / 6 HIS A2544
ASP A2644
SER A2591
PRO A2688
 None
 1.17A 4apjA-1miuA:
0.0
4apjP-1miuA:
undetectable		 4apjA-1miuA:
22.70
4apjP-1miuA:
1.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_A_TCWA1126_1
(TRANSTHYRETIN)		 1miu BREAST CANCER TYPE 2
SUSCEPTIBILITY
PROTEIN
(Mus
musculus) 		4 / 6 LEU A2906
ALA A2948
LEU A2946
SER A2933
 None
 0.92A 4d7bB-1miuA:
0.0		 4d7bB-1miuA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I89_A_1FLA201_1
(TRANSTHYRETIN)		 1miu BREAST CANCER TYPE 2
SUSCEPTIBILITY
PROTEIN
(Mus
musculus) 		4 / 6 LEU A2906
ALA A2948
LEU A2946
SER A2933
 None
 1.00A 4i89A-1miuA:
undetectable		 4i89A-1miuA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA3_L_ACTL301_0
(C2095 HEAVY CHAIN
C2095 LIGHT CHAIN)		 1miu BREAST CANCER TYPE 2
SUSCEPTIBILITY
PROTEIN
(Mus
musculus) 		3 / 3 PRO A2688
ASN A2543
HIS A2544
 None
 0.97A 4ma3H-1miuA:
0.1
4ma3L-1miuA:
undetectable		 4ma3H-1miuA:
15.51
4ma3L-1miuA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 1miu BREAST CANCER TYPE 2
SUSCEPTIBILITY
PROTEIN
(Mus
musculus) 		5 / 12 ILE A2509
GLY A2497
GLY A2499
SER A2404
LEU A2401
 None
 1.10A 4mwzA-1miuA:
undetectable		 4mwzA-1miuA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_A_4TXA201_1
(TRANSTHYRETIN)		 1miu BREAST CANCER TYPE 2
SUSCEPTIBILITY
PROTEIN
(Mus
musculus) 		4 / 6 LEU A2906
ALA A2948
LEU A2946
SER A2933
 None
 0.99A 5bojA-1miuA:
undetectable		 5bojA-1miuA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_A_6J3A201_0
(TRANSTHYRETIN)		 1miu BREAST CANCER TYPE 2
SUSCEPTIBILITY
PROTEIN
(Mus
musculus) 		4 / 6 LEU A2906
ALA A2948
LEU A2946
SER A2933
 None
 0.95A 5l4iA-1miuA:
undetectable		 5l4iA-1miuA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		 1miu BREAST CANCER TYPE 2
SUSCEPTIBILITY
PROTEIN
(Mus
musculus) 		5 / 12 ILE A2672
LEU A2642
GLY A2676
ALA A2677
LEU A2697
 None
 1.11A 5zwrA-1miuA:
undetectable		 5zwrA-1miuA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_A_TKTA508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 1miu BREAST CANCER TYPE 2
SUSCEPTIBILITY
PROTEIN
(Mus
musculus) 		4 / 8 ASP A2527
ILE A2509
ARG A2415
ASN A2512
 None
 1.21A 6hisA-1miuA:
2.2
6hisB-1miuA:
2.2		 6hisA-1miuA:
8.14
6hisB-1miuA:
8.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_B_TKTB508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 1miu BREAST CANCER TYPE 2
SUSCEPTIBILITY
PROTEIN
(Mus
musculus) 		4 / 8 ASP A2527
ILE A2509
ARG A2415
ASN A2512
 None
 1.21A 6hisB-1miuA:
2.3
6hisC-1miuA:
2.3		 6hisB-1miuA:
8.14
6hisC-1miuA:
8.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_C_TKTC508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 1miu BREAST CANCER TYPE 2
SUSCEPTIBILITY
PROTEIN
(Mus
musculus) 		4 / 8 ASP A2527
ILE A2509
ARG A2415
ASN A2512
 None
 1.21A 6hisC-1miuA:
2.2
6hisD-1miuA:
2.4		 6hisC-1miuA:
8.14
6hisD-1miuA:
8.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_D_TKTD501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 1miu BREAST CANCER TYPE 2
SUSCEPTIBILITY
PROTEIN
(Mus
musculus) 		4 / 8 ASP A2527
ILE A2509
ARG A2415
ASN A2512
 None
 1.19A 6hisD-1miuA:
2.2
6hisE-1miuA:
2.3		 6hisD-1miuA:
8.14
6hisE-1miuA:
8.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_E_TKTE501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 1miu BREAST CANCER TYPE 2
SUSCEPTIBILITY
PROTEIN
(Mus
musculus) 		4 / 8 ASN A2512
ASP A2527
ILE A2509
ARG A2415
 None
 1.20A 6hisA-1miuA:
2.2
6hisE-1miuA:
2.3		 6hisA-1miuA:
8.14
6hisE-1miuA:
8.14