SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1miv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_B_STRB2_1
(PROGESTERONE
RECEPTOR)		 1miv TRNA CCA-ADDING
ENZYME
(Geobacillus
stearothermophil
us) 		5 / 12 LEU A 234
LEU A 215
ASN A 221
LEU A 220
LEU A 255
 None
 1.18A 1a28B-1mivA:
undetectable		 1a28B-1mivA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_1
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 1miv TRNA CCA-ADDING
ENZYME
(Geobacillus
stearothermophil
us) 		3 / 3 ARG A 160
ARG A 163
ILE A 141
 None
 0.79A 1uobA-1mivA:
0.0		 1uobA-1mivA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)		 1miv TRNA CCA-ADDING
ENZYME
(Geobacillus
stearothermophil
us) 		4 / 5 ILE A 291
LEU A 302
ALA A 310
GLU A 314
 None
 1.15A 1xvaA-1mivA:
undetectable
1xvaB-1mivA:
undetectable		 1xvaA-1mivA:
19.90
1xvaB-1mivA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FR3_A_REAA300_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
2)		 1miv TRNA CCA-ADDING
ENZYME
(Geobacillus
stearothermophil
us) 		5 / 12 LEU A 104
ILE A 118
ALA A 119
VAL A  29
LEU A  15
 None
 1.01A 2fr3A-1mivA:
undetectable		 2fr3A-1mivA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 1miv TRNA CCA-ADDING
ENZYME
(Geobacillus
stearothermophil
us) 		5 / 12 PHE A 164
LEU A 168
GLU A 167
ARG A  36
ALA A  28
 None
 1.37A 3apvA-1mivA:
0.0		 3apvA-1mivA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 1miv TRNA CCA-ADDING
ENZYME
(Geobacillus
stearothermophil
us) 		5 / 12 VAL A  25
GLY A  26
PHE A 113
VAL A  41
ALA A 117
 None
 1.33A 3dh0A-1mivA:
undetectable		 3dh0A-1mivA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		 1miv TRNA CCA-ADDING
ENZYME
(Geobacillus
stearothermophil
us) 		5 / 12 GLY A 380
ARG A 375
ALA A 372
ALA A 369
ASP A 371
 None
 1.01A 3keeC-1mivA:
undetectable		 3keeC-1mivA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_A_CL6A506_1
(CHOLESTEROL
24-HYDROXYLASE)		 1miv TRNA CCA-ADDING
ENZYME
(Geobacillus
stearothermophil
us) 		5 / 9 VAL A  41
LEU A  15
ILE A  11
ALA A   8
ALA A  22
 None
 1.07A 3mdvA-1mivA:
0.0		 3mdvA-1mivA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1miv TRNA CCA-ADDING
ENZYME
(Geobacillus
stearothermophil
us) 		4 / 7 ALA A 119
ILE A 118
ARG A 111
GLY A  27
 None
 0.93A 3v4tH-1mivA:
undetectable		 3v4tH-1mivA:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_TESA1000_1
(ANDROGEN RECEPTOR)		 1miv TRNA CCA-ADDING
ENZYME
(Geobacillus
stearothermophil
us) 		5 / 12 LEU A 234
LEU A 215
ASN A 221
LEU A 220
MET A 195
 None
 1.15A 3zqtA-1mivA:
undetectable		 3zqtA-1mivA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_D_PARD500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 1miv TRNA CCA-ADDING
ENZYME
(Geobacillus
stearothermophil
us) 		4 / 8 PHE A 164
THR A 114
GLU A 134
ASP A 128
 None
 1.33A 4qb9D-1mivA:
0.0		 4qb9D-1mivA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_1
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 1miv TRNA CCA-ADDING
ENZYME
(Geobacillus
stearothermophil
us) 		3 / 3 ARG A 160
ASN A 116
ASP A  42
 None
 0.84A 5gwxA-1mivA:
undetectable		 5gwxA-1mivA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_1
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 1miv TRNA CCA-ADDING
ENZYME
(Geobacillus
stearothermophil
us) 		3 / 3 ARG A 160
ASN A 116
ASP A 107
 None
 0.84A 5gwxA-1mivA:
undetectable		 5gwxA-1mivA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQB_B_IBPB706_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 1miv TRNA CCA-ADDING
ENZYME
(Geobacillus
stearothermophil
us) 		5 / 8 ARG A 163
ALA A 161
LEU A 202
LEU A 220
LEU A 215
 None
 1.29A 5jqbA-1mivA:
undetectable
5jqbB-1mivA:
undetectable		 5jqbA-1mivA:
21.03
5jqbB-1mivA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 1miv TRNA CCA-ADDING
ENZYME
(Geobacillus
stearothermophil
us) 		3 / 3 ASP A 107
ARG A 110
ASP A  42
 None
 0.86A 5zvgA-1mivA:
undetectable		 5zvgA-1mivA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 1miv TRNA CCA-ADDING
ENZYME
(Geobacillus
stearothermophil
us) 		3 / 3 ASP A 107
ARG A 110
ASP A  42
 None
 0.86A 5zvgB-1mivA:
undetectable		 5zvgB-1mivA:
24.06