SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mj0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_E_IPHE101_0
(INSULIN)		 1mj0 SANK E3_5 PROTEIN
(-) 		5 / 11 ILE A  95
LEU A  84
HIS A 102
LEU A 100
ALA A 104
 TRS  A 200 (-3.9A)
None
None
None
None
 1.09A 4p65E-1mj0A:
undetectable
4p65F-1mj0A:
undetectable
4p65J-1mj0A:
undetectable
4p65L-1mj0A:
undetectable		 4p65E-1mj0A:
11.01
4p65F-1mj0A:
13.51
4p65J-1mj0A:
13.51
4p65L-1mj0A:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_E_IPHE101_0
(INSULIN)		 1mj0 SANK E3_5 PROTEIN
(-) 		5 / 11 ILE A 128
LEU A 117
HIS A 135
LEU A 133
ALA A 137
 None
 1.07A 4p65E-1mj0A:
undetectable
4p65F-1mj0A:
undetectable
4p65J-1mj0A:
undetectable
4p65L-1mj0A:
undetectable		 4p65E-1mj0A:
11.01
4p65F-1mj0A:
13.51
4p65J-1mj0A:
13.51
4p65L-1mj0A:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_I_IPHI101_0
(INSULIN)		 1mj0 SANK E3_5 PROTEIN
(-) 		5 / 12 VAL A  30
LEU A  18
LEU A  51
ILE A  62
ALA A  71
 None
 0.98A 4p65B-1mj0A:
undetectable
4p65D-1mj0A:
undetectable
4p65I-1mj0A:
undetectable
4p65J-1mj0A:
undetectable		 4p65B-1mj0A:
13.51
4p65D-1mj0A:
13.51
4p65I-1mj0A:
11.01
4p65J-1mj0A:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_I_IPHI101_0
(INSULIN)		 1mj0 SANK E3_5 PROTEIN
(-) 		5 / 12 VAL A  96
LEU A  84
LEU A 117
ILE A 128
ALA A 137
 None
 1.02A 4p65B-1mj0A:
undetectable
4p65D-1mj0A:
undetectable
4p65I-1mj0A:
undetectable
4p65J-1mj0A:
undetectable		 4p65B-1mj0A:
13.51
4p65D-1mj0A:
13.51
4p65I-1mj0A:
11.01
4p65J-1mj0A:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_K_IPHK101_0
(INSULIN)		 1mj0 SANK E3_5 PROTEIN
(-) 		5 / 12 LEU A 117
VAL A  96
LEU A  84
ILE A 128
ALA A 137
 None
 1.06A 4p65F-1mj0A:
undetectable
4p65H-1mj0A:
undetectable
4p65K-1mj0A:
undetectable
4p65L-1mj0A:
undetectable		 4p65F-1mj0A:
13.51
4p65H-1mj0A:
13.51
4p65K-1mj0A:
11.01
4p65L-1mj0A:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_A_SAMA301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 1mj0 SANK E3_5 PROTEIN
(-) 		3 / 3 THR A  90
SER A  56
ASP A  77
 None
 0.73A 5kvaA-1mj0A:
undetectable		 5kvaA-1mj0A:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 1mj0 SANK E3_5 PROTEIN
(-) 		3 / 3 THR A  90
SER A  56
ASP A  77
 None
 0.72A 5kvaB-1mj0A:
undetectable		 5kvaB-1mj0A:
24.34