SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mj8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H8S_A_AICA1000_1
(MUTANT AL2 6E7P9G)		 1mj8 IMMUNOGLOBULIN
MS6-126
(Mus
musculus) 		6 / 12 TRP H  33
ASN H  35
VAL H  37
ASN H  50
ALA H  93
TRP H 103
 PO4  H 805 (-4.7A)
PO4  H 805 ( 3.1A)
None
PO4  H 805 (-4.1A)
GOL  H 701 ( 4.2A)
None
 0.34A 1h8sA-1mj8H:
14.7		 1h8sA-1mj8H:
44.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M4I_A_KANA500_1
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 1mj8 IMMUNOGLOBULIN
MS6-126
(Mus
musculus) 		4 / 8 GLU H  10
GLY H   8
SER H  21
THR H  77
 None
 0.83A 1m4iA-1mj8H:
0.1		 1m4iA-1mj8H:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1mj8 IMMUNOGLOBULIN
MS6-126
(Mus
musculus) 		4 / 7 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.82A 1usqA-1mj8H:
2.1		 1usqA-1mj8H:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1mj8 IMMUNOGLOBULIN
MS6-126
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.83A 1usqB-1mj8H:
undetectable		 1usqB-1mj8H:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1mj8 IMMUNOGLOBULIN
MS6-126
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.82A 1usqC-1mj8H:
2.1		 1usqC-1mj8H:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1mj8 IMMUNOGLOBULIN
MS6-126
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.83A 1usqD-1mj8H:
undetectable		 1usqD-1mj8H:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1mj8 IMMUNOGLOBULIN
MS6-126
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.82A 1usqE-1mj8H:
2.2		 1usqE-1mj8H:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1mj8 IMMUNOGLOBULIN
MS6-126
(Mus
musculus) 		4 / 7 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.82A 1usqF-1mj8H:
2.1		 1usqF-1mj8H:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_E_CLME1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1mj8 IMMUNOGLOBULIN
MS6-126
(Mus
musculus) 		5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
 None
 1.19A 2jkjE-1mj8H:
2.1		 2jkjE-1mj8H:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1mj8 IMMUNOGLOBULIN
MS6-126
(Mus
musculus) 		4 / 7 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.88A 2jklC-1mj8H:
2.0		 2jklC-1mj8H:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1mj8 IMMUNOGLOBULIN
MS6-126
(Mus
musculus) 		4 / 7 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.87A 2jklD-1mj8H:
2.1		 2jklD-1mj8H:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1mj8 IMMUNOGLOBULIN
MS6-126
(Mus
musculus) 		5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
 None
 1.19A 2jklE-1mj8H:
2.0		 2jklE-1mj8H:
18.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MTH_A_ACTA302_0
(ANTIBODY FAB HEAVY
CHAIN)		 1mj8 IMMUNOGLOBULIN
MS6-126
(Mus
musculus) 		5 / 5 SER H 112
ALA H 114
PHE H 148
LEU H 178
ASP H 183
 None
 0.49A 5mthA-1mj8H:
28.2		 5mthA-1mj8H:
76.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_1
(PROTEIN CYP51)		 1mj8 IMMUNOGLOBULIN
MS6-126
(Mus
musculus) 		5 / 12 ALA H  16
PHE H 148
TYR H 147
LEU H 108
THR H  83
 None
 1.11A 5tl8A-1mj8H:
undetectable		 5tl8A-1mj8H:
17.28