SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mje'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		 1mje BREAST CANCER 2
(Mus
musculus) 		4 / 7 LEU A2892
VAL A2743
TYR A2925
LEU A2915
 None
 0.83A 1cqpA-1mjeA:
undetectable
1cqpB-1mjeA:
undetectable		 1cqpA-1mjeA:
15.49
1cqpB-1mjeA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		 1mje BREAST CANCER 2
(Mus
musculus) 		4 / 7 LEU A3043
VAL A2991
LYS A3076
LEU A3012
 None
 0.81A 1cqpA-1mjeA:
undetectable
1cqpB-1mjeA:
undetectable		 1cqpA-1mjeA:
15.49
1cqpB-1mjeA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FO4_B_SALB4005_1
(XANTHINE
DEHYDROGENASE)		 1mje BREAST CANCER 2
(Mus
musculus) 		4 / 7 SER A3049
THR A3055
VAL A3021
ALA A3007
 None
 1.06A 1fo4B-1mjeA:
undetectable		 1fo4B-1mjeA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_A_BEZA1162_0
(PEROXIREDOXIN 5)		 1mje BREAST CANCER 2
(Mus
musculus) 		5 / 10 THR A2528
PRO A2529
GLY A2530
LEU A2575
GLY A2429
 None
 1.10A 1h4oA-1mjeA:
undetectable
1h4oB-1mjeA:
undetectable		 1h4oA-1mjeA:
13.61
1h4oB-1mjeA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)		 1mje BREAST CANCER 2
(Mus
musculus) 		4 / 8 THR A2528
PRO A2529
GLY A2530
LEU A2575
 None
 0.72A 1h4oG-1mjeA:
undetectable		 1h4oG-1mjeA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_B_BEZB1162_0
(PEROXIREDOXIN-5)		 1mje BREAST CANCER 2
(Mus
musculus) 		4 / 7 THR A2528
PRO A2529
GLY A2530
LEU A2575
 None
 0.80A 2vl2B-1mjeA:
undetectable		 2vl2B-1mjeA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA2_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 1mje BREAST CANCER 2
(Mus
musculus) 		3 / 3 LYS A3002
LYS A3033
VAL A3000
 None
 0.97A 3brfA-1mjeA:
0.0		 3brfA-1mjeA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B304_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1mje BREAST CANCER 2
(Mus
musculus) 		4 / 5 ASN A2587
THR A2434
SER A2436
ARG A2441
 None
 1.20A 3hlwB-1mjeA:
undetectable		 3hlwB-1mjeA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_B_MTXB164_1
(DIHYDROFOLATE
REDUCTASE)		 1mje BREAST CANCER 2
(Mus
musculus) 		5 / 12 ILE A2614
LEU A2653
GLN A2652
ILE A2672
LEU A2642
 None
 1.32A 3ia4B-1mjeA:
undetectable		 3ia4B-1mjeA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1mje BREAST CANCER 2
(Mus
musculus) 		5 / 12 LEU A3009
LEU A3012
GLY A3025
ALA A3058
LEU A3043
 None
 1.12A 3n8xB-1mjeA:
1.6		 3n8xB-1mjeA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NV6_A_CAMA422_0
(CYTOCHROME P450)		 1mje BREAST CANCER 2
(Mus
musculus) 		3 / 3 GLY A2517
ILE A2548
VAL A2549
 None
 0.46A 3nv6A-1mjeA:
undetectable		 3nv6A-1mjeA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VM4_A_IZPA1_1
(FATTY ACID
ALPHA-HYDROXYLASE)		 1mje BREAST CANCER 2
(Mus
musculus) 		4 / 5 LEU A2502
PHE A2521
PRO A2510
ALA A2516
 None
 1.41A 3vm4A-1mjeA:
0.0		 3vm4A-1mjeA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUH_A_ACTA610_0
(SERUM ALBUMIN)		 1mje BREAST CANCER 2
(Mus
musculus) 		3 / 3 VAL A2959
SER A2960
THR A2963
 None
 0.44A 4luhA-1mjeA:
0.0		 4luhA-1mjeA:
22.64