SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mjl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CMA_A_SAMA105_0
(PROTEIN (MET
REPRESSOR))
1mjl METHIONINE REPRESSOR
PROTEIN METJ

(Escherichia
coli)
7 / 8 GLU A  39
ARG A  42
ARG A  43
LEU A  56
GLU A  59
HIS A  63
LEU A  70
None
None
None
None
None
SAM  A 200 ( 2.9A)
None
0.40A 1cmaA-1mjlA:
17.4
1cmaB-1mjlA:
15.5
1cmaA-1mjlA:
99.04
1cmaB-1mjlA:
99.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CMA_B_SAMB105_0
(PROTEIN (MET
REPRESSOR))
1mjl METHIONINE REPRESSOR
PROTEIN METJ

(Escherichia
coli)
7 / 11 GLU A  39
ARG A  42
ARG A  43
LEU A  56
GLU A  59
HIS A  63
LEU A  70
None
None
None
None
None
SAM  A 200 ( 2.9A)
None
0.34A 1cmaA-1mjlA:
17.4
1cmaB-1mjlA:
15.5
1cmaA-1mjlA:
99.04
1cmaB-1mjlA:
99.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CMC_A_SAMA105_0
(MET REPRESSOR)
1mjl METHIONINE REPRESSOR
PROTEIN METJ

(Escherichia
coli)
7 / 10 GLU A  39
ARG A  43
LEU A  56
GLU A  59
HIS A  63
LEU A  70
PRO A  71
None
None
None
None
SAM  A 200 ( 2.9A)
None
None
0.25A 1cmcA-1mjlA:
19.0
1cmcB-1mjlA:
18.7
1cmcA-1mjlA:
99.04
1cmcB-1mjlA:
99.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CMC_B_SAMB105_0
(MET REPRESSOR)
1mjl METHIONINE REPRESSOR
PROTEIN METJ

(Escherichia
coli)
7 / 10 GLU A  39
ARG A  42
ARG A  43
LEU A  56
GLU A  59
HIS A  63
LEU A  70
None
None
None
None
None
SAM  A 200 ( 2.9A)
None
0.31A 1cmcA-1mjlA:
19.0
1cmcB-1mjlA:
18.7
1cmcA-1mjlA:
99.04
1cmcB-1mjlA:
99.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CMC_B_SAMB105_0
(MET REPRESSOR)
1mjl METHIONINE REPRESSOR
PROTEIN METJ

(Escherichia
coli)
5 / 10 GLU A  39
ARG A  42
ARG A  43
LEU A  70
ALA A  60
None
1.36A 1cmcA-1mjlA:
19.0
1cmcB-1mjlA:
18.7
1cmcA-1mjlA:
99.04
1cmcB-1mjlA:
99.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MJ2_A_SAMA2200_0
(PROTEIN (METHIONINE
REPRESSOR))
1mjl METHIONINE REPRESSOR
PROTEIN METJ

(Escherichia
coli)
6 / 12 ALA A  60
GLU A  39
ARG A  42
ARG A  43
LEU A  70
PRO A  71
None
1.24A 1mj2A-1mjlA:
14.6
1mj2B-1mjlA:
15.5
1mj2A-1mjlA:
100.00
1mj2B-1mjlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MJ2_A_SAMA2200_0
(PROTEIN (METHIONINE
REPRESSOR))
1mjl METHIONINE REPRESSOR
PROTEIN METJ

(Escherichia
coli)
8 / 12 GLU A  39
ARG A  42
ARG A  43
LEU A  56
GLU A  59
HIS A  63
LEU A  70
PRO A  71
None
None
None
None
None
SAM  A 200 ( 2.9A)
None
None
0.32A 1mj2A-1mjlA:
14.6
1mj2B-1mjlA:
15.5
1mj2A-1mjlA:
100.00
1mj2B-1mjlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MJ2_A_SAMA2201_0
(PROTEIN (METHIONINE
REPRESSOR))
1mjl METHIONINE REPRESSOR
PROTEIN METJ

(Escherichia
coli)
9 / 9 GLU A  39
ARG A  42
ARG A  43
LEU A  56
GLU A  59
ALA A  60
HIS A  63
LEU A  70
PRO A  71
None
None
None
None
None
None
SAM  A 200 ( 2.9A)
None
None
0.29A 1mj2A-1mjlA:
14.6
1mj2A-1mjlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MJ2_A_SAMA2201_1
(PROTEIN (METHIONINE
REPRESSOR))
1mjl METHIONINE REPRESSOR
PROTEIN METJ

(Escherichia
coli)
4 / 4 HIS A  63
ALA A  64
PHE A  65
GLY A  67
SAM  A 200 ( 2.9A)
SAM  A 200 (-4.0A)
SAM  A 200 (-3.8A)
SAM  A 200 ( 4.1A)
0.27A 1mj2B-1mjlA:
15.5
1mj2B-1mjlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MJ2_C_SAMC1200_0
(PROTEIN (METHIONINE
REPRESSOR))
1mjl METHIONINE REPRESSOR
PROTEIN METJ

(Escherichia
coli)
9 / 9 GLU A  39
ARG A  42
ARG A  43
LEU A  56
GLU A  59
ALA A  60
HIS A  63
LEU A  70
PRO A  71
None
None
None
None
None
None
SAM  A 200 ( 2.9A)
None
None
0.32A 1mj2C-1mjlA:
13.7
1mj2C-1mjlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MJ2_C_SAMC1200_1
(PROTEIN (METHIONINE
REPRESSOR))
1mjl METHIONINE REPRESSOR
PROTEIN METJ

(Escherichia
coli)
4 / 4 HIS A  63
ALA A  64
PHE A  65
GLY A  67
SAM  A 200 ( 2.9A)
SAM  A 200 (-4.0A)
SAM  A 200 (-3.8A)
SAM  A 200 ( 4.1A)
0.25A 1mj2D-1mjlA:
15.5
1mj2D-1mjlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MJ2_C_SAMC2199_0
(PROTEIN (METHIONINE
REPRESSOR))
1mjl METHIONINE REPRESSOR
PROTEIN METJ

(Escherichia
coli)
6 / 12 ALA A  60
GLU A  39
ARG A  42
ARG A  43
LEU A  70
PRO A  71
None
1.22A 1mj2C-1mjlA:
13.7
1mj2D-1mjlA:
15.5
1mj2C-1mjlA:
100.00
1mj2D-1mjlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MJ2_C_SAMC2199_0
(PROTEIN (METHIONINE
REPRESSOR))
1mjl METHIONINE REPRESSOR
PROTEIN METJ

(Escherichia
coli)
8 / 12 GLU A  39
ARG A  42
ARG A  43
LEU A  56
GLU A  59
HIS A  63
LEU A  70
PRO A  71
None
None
None
None
None
SAM  A 200 ( 2.9A)
None
None
0.31A 1mj2C-1mjlA:
13.7
1mj2D-1mjlA:
15.5
1mj2C-1mjlA:
100.00
1mj2D-1mjlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MJL_A_SAMA200_0
(METHIONINE REPRESSOR
PROTEIN METJ)
1mjl METHIONINE REPRESSOR
PROTEIN METJ

(Escherichia
coli)
8 / 11 GLU A  39
ARG A  42
ARG A  43
LEU A  56
GLU A  59
ALA A  60
HIS A  63
LEU A  70
None
None
None
None
None
None
SAM  A 200 ( 2.9A)
None
0.18A 1mjlA-1mjlA:
21.9
1mjlB-1mjlA:
14.6
1mjlA-1mjlA:
100.00
1mjlB-1mjlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MJL_B_SAMB400_0
(METHIONINE REPRESSOR
PROTEIN METJ)
1mjl METHIONINE REPRESSOR
PROTEIN METJ

(Escherichia
coli)
6 / 9 GLU A  39
ARG A  43
LEU A  56
GLU A  59
HIS A  63
LEU A  70
None
None
None
None
SAM  A 200 ( 2.9A)
None
0.02A 1mjlA-1mjlA:
21.9
1mjlB-1mjlA:
14.6
1mjlA-1mjlA:
100.00
1mjlB-1mjlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MJO_A_SAMA199_0
(METHIONINE REPRESSOR)
1mjl METHIONINE REPRESSOR
PROTEIN METJ

(Escherichia
coli)
9 / 9 GLU A  39
ARG A  42
ARG A  43
LEU A  56
GLU A  59
ALA A  60
HIS A  63
LEU A  70
PRO A  71
None
None
None
None
None
None
SAM  A 200 ( 2.9A)
None
None
0.29A 1mjoA-1mjlA:
16.0
1mjoA-1mjlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MJO_A_SAMA199_1
(METHIONINE REPRESSOR)
1mjl METHIONINE REPRESSOR
PROTEIN METJ

(Escherichia
coli)
4 / 4 HIS A  63
ALA A  64
PHE A  65
GLY A  67
SAM  A 200 ( 2.9A)
SAM  A 200 (-4.0A)
SAM  A 200 (-3.8A)
SAM  A 200 ( 4.1A)
0.28A 1mjoB-1mjlA:
15.4
1mjoB-1mjlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MJO_B_SAMB200_0
(METHIONINE REPRESSOR)
1mjl METHIONINE REPRESSOR
PROTEIN METJ

(Escherichia
coli)
4 / 4 HIS A  63
ALA A  64
PHE A  65
GLY A  67
SAM  A 200 ( 2.9A)
SAM  A 200 (-4.0A)
SAM  A 200 (-3.8A)
SAM  A 200 ( 4.1A)
0.37A 1mjoA-1mjlA:
16.0
1mjoA-1mjlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MJO_B_SAMB200_1
(METHIONINE REPRESSOR)
1mjl METHIONINE REPRESSOR
PROTEIN METJ

(Escherichia
coli)
9 / 9 GLU A  39
ARG A  42
ARG A  43
LEU A  56
GLU A  59
ALA A  60
HIS A  63
LEU A  70
PRO A  71
None
None
None
None
None
None
SAM  A 200 ( 2.9A)
None
None
0.30A 1mjoB-1mjlA:
15.4
1mjoB-1mjlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MJO_C_SAMC200_0
(METHIONINE REPRESSOR)
1mjl METHIONINE REPRESSOR
PROTEIN METJ

(Escherichia
coli)
5 / 12 ALA A  60
GLU A  39
ARG A  42
ARG A  43
PRO A  71
None
1.14A 1mjoC-1mjlA:
14.3
1mjoD-1mjlA:
14.2
1mjoC-1mjlA:
100.00
1mjoD-1mjlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MJO_C_SAMC200_0
(METHIONINE REPRESSOR)
1mjl METHIONINE REPRESSOR
PROTEIN METJ

(Escherichia
coli)
8 / 12 GLU A  39
ARG A  42
ARG A  43
LEU A  56
GLU A  59
HIS A  63
LEU A  70
PRO A  71
None
None
None
None
None
SAM  A 200 ( 2.9A)
None
None
0.29A 1mjoC-1mjlA:
14.3
1mjoD-1mjlA:
14.2
1mjoC-1mjlA:
100.00
1mjoD-1mjlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MJO_D_SAMD200_0
(METHIONINE REPRESSOR)
1mjl METHIONINE REPRESSOR
PROTEIN METJ

(Escherichia
coli)
9 / 9 GLU A  39
ARG A  42
ARG A  43
LEU A  56
GLU A  59
ALA A  60
HIS A  63
LEU A  70
PRO A  71
None
None
None
None
None
None
SAM  A 200 ( 2.9A)
None
None
0.29A 1mjoC-1mjlA:
14.3
1mjoC-1mjlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MJO_D_SAMD200_1
(METHIONINE REPRESSOR)
1mjl METHIONINE REPRESSOR
PROTEIN METJ

(Escherichia
coli)
4 / 4 HIS A  63
ALA A  64
PHE A  65
GLY A  67
SAM  A 200 ( 2.9A)
SAM  A 200 (-4.0A)
SAM  A 200 (-3.8A)
SAM  A 200 ( 4.1A)
0.24A 1mjoD-1mjlA:
14.2
1mjoD-1mjlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MJQ_A_SAMA200_0
(METHIONINE REPRESSOR)
1mjl METHIONINE REPRESSOR
PROTEIN METJ

(Escherichia
coli)
7 / 11 GLU A  39
ARG A  43
LEU A  56
GLU A  59
HIS A  63
LEU A  70
PRO A  71
None
None
None
None
SAM  A 200 ( 2.9A)
None
None
0.34A 1mjqA-1mjlA:
14.0
1mjqB-1mjlA:
15.4
1mjqA-1mjlA:
100.00
1mjqB-1mjlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MJQ_A_SAMA200_0
(METHIONINE REPRESSOR)
1mjl METHIONINE REPRESSOR
PROTEIN METJ

(Escherichia
coli)
5 / 11 GLU A  39
ARG A  43
LEU A  70
PRO A  71
ALA A  60
None
1.25A 1mjqA-1mjlA:
14.0
1mjqB-1mjlA:
15.4
1mjqA-1mjlA:
100.00
1mjqB-1mjlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MJQ_B_SAMB200_0
(METHIONINE REPRESSOR)
1mjl METHIONINE REPRESSOR
PROTEIN METJ

(Escherichia
coli)
7 / 11 GLU A  39
ARG A  43
LEU A  56
GLU A  59
HIS A  63
LEU A  70
PRO A  71
None
None
None
None
SAM  A 200 ( 2.9A)
None
None
0.28A 1mjqA-1mjlA:
14.0
1mjqB-1mjlA:
15.4
1mjqA-1mjlA:
100.00
1mjqB-1mjlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MJQ_C_SAMC199_0
(METHIONINE REPRESSOR)
1mjl METHIONINE REPRESSOR
PROTEIN METJ

(Escherichia
coli)
7 / 10 GLU A  39
ARG A  43
LEU A  56
GLU A  59
HIS A  63
LEU A  70
PRO A  71
None
None
None
None
SAM  A 200 ( 2.9A)
None
None
0.34A 1mjqC-1mjlA:
14.1
1mjqD-1mjlA:
15.3
1mjqC-1mjlA:
100.00
1mjqD-1mjlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MJQ_C_SAMC199_0
(METHIONINE REPRESSOR)
1mjl METHIONINE REPRESSOR
PROTEIN METJ

(Escherichia
coli)
5 / 10 GLU A  39
ARG A  43
LEU A  70
PRO A  71
ALA A  60
None
1.28A 1mjqC-1mjlA:
14.1
1mjqD-1mjlA:
15.3
1mjqC-1mjlA:
100.00
1mjqD-1mjlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MJQ_D_SAMD200_0
(METHIONINE REPRESSOR)
1mjl METHIONINE REPRESSOR
PROTEIN METJ

(Escherichia
coli)
8 / 12 GLU A  39
ARG A  43
LEU A  56
GLU A  59
ALA A  60
HIS A  63
LEU A  70
PRO A  71
None
None
None
None
None
SAM  A 200 ( 2.9A)
None
None
0.29A 1mjqC-1mjlA:
14.1
1mjqD-1mjlA:
15.3
1mjqC-1mjlA:
100.00
1mjqD-1mjlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MJQ_G_SAMG199_0
(METHIONINE REPRESSOR)
1mjl METHIONINE REPRESSOR
PROTEIN METJ

(Escherichia
coli)
7 / 10 GLU A  39
ARG A  43
GLU A  59
ALA A  60
HIS A  63
LEU A  70
PRO A  71
None
None
None
None
SAM  A 200 ( 2.9A)
None
None
0.33A 1mjqG-1mjlA:
14.1
1mjqH-1mjlA:
15.4
1mjqG-1mjlA:
100.00
1mjqH-1mjlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MJQ_G_SAMG199_0
(METHIONINE REPRESSOR)
1mjl METHIONINE REPRESSOR
PROTEIN METJ

(Escherichia
coli)
5 / 10 GLU A  39
ARG A  43
LEU A  70
PRO A  71
ALA A  60
None
1.23A 1mjqG-1mjlA:
14.1
1mjqH-1mjlA:
15.4
1mjqG-1mjlA:
100.00
1mjqH-1mjlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MJQ_H_SAMH200_0
(METHIONINE REPRESSOR)
1mjl METHIONINE REPRESSOR
PROTEIN METJ

(Escherichia
coli)
7 / 10 GLU A  39
ARG A  43
LEU A  56
GLU A  59
HIS A  63
LEU A  70
PRO A  71
None
None
None
None
SAM  A 200 ( 2.9A)
None
None
0.29A 1mjqG-1mjlA:
14.1
1mjqH-1mjlA:
15.4
1mjqG-1mjlA:
100.00
1mjqH-1mjlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MJQ_I_SAMI199_0
(METHIONINE REPRESSOR)
1mjl METHIONINE REPRESSOR
PROTEIN METJ

(Escherichia
coli)
7 / 11 GLU A  39
ARG A  43
LEU A  56
GLU A  59
HIS A  63
LEU A  70
PRO A  71
None
None
None
None
SAM  A 200 ( 2.9A)
None
None
0.32A 1mjqI-1mjlA:
13.8
1mjqJ-1mjlA:
15.5
1mjqI-1mjlA:
100.00
1mjqJ-1mjlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MJQ_I_SAMI199_0
(METHIONINE REPRESSOR)
1mjl METHIONINE REPRESSOR
PROTEIN METJ

(Escherichia
coli)
5 / 11 GLU A  39
ARG A  43
LEU A  70
PRO A  71
ALA A  60
None
1.29A 1mjqI-1mjlA:
13.8
1mjqJ-1mjlA:
15.5
1mjqI-1mjlA:
100.00
1mjqJ-1mjlA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MJQ_J_SAMJ200_0
(METHIONINE REPRESSOR)
1mjl METHIONINE REPRESSOR
PROTEIN METJ

(Escherichia
coli)
8 / 12 GLU A  39
ARG A  43
LEU A  56
GLU A  59
ALA A  60
HIS A  63
LEU A  70
PRO A  71
None
None
None
None
None
SAM  A 200 ( 2.9A)
None
None
0.29A 1mjqI-1mjlA:
13.8
1mjqJ-1mjlA:
15.5
1mjqI-1mjlA:
100.00
1mjqJ-1mjlA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LTW_A_HLZA302_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)
1mjl METHIONINE REPRESSOR
PROTEIN METJ

(Escherichia
coli)
4 / 6 LEU A  56
GLU A  59
ARG A  43
HIS A  50
None
1.39A 3ltwA-1mjlA:
undetectable
3ltwA-1mjlA:
16.19