SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mmf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CTR_A_TFPA153_1
(CALMODULIN)		 1mmf GLYCEROL DEHYDRASE
BETA SUBUNIT
(Klebsiella
pneumoniae) 		5 / 9 ILE B  32
GLU B  64
GLU B  65
ALA B 140
VAL B  30
 None
 1.15A 1ctrA-1mmfB:
undetectable		 1ctrA-1mmfB:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JZS_A_MRCA1301_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 1mmf GLYCEROL DEHYDRASE
BETA SUBUNIT
(Klebsiella
pneumoniae) 		5 / 11 GLY B  35
PRO B  36
GLY B 103
GLN B 100
ILE B  47
 None
 1.21A 1jzsA-1mmfB:
undetectable		 1jzsA-1mmfB:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JZS_A_MRCA1301_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 1mmf GLYCEROL DEHYDRASE
BETA SUBUNIT
(Klebsiella
pneumoniae) 		5 / 11 GLY B  35
PRO B  36
HIS B  51
GLN B 100
LEU B 127
 None
 1.10A 1jzsA-1mmfB:
undetectable		 1jzsA-1mmfB:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB503_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1mmf GLYCEROL DEHYDRASE
BETA SUBUNIT
(Klebsiella
pneumoniae) 		4 / 6 ARG B  70
ALA B  21
ILE B  74
PRO B 184
 None
 1.16A 1oniB-1mmfB:
undetectable
1oniC-1mmfB:
undetectable		 1oniB-1mmfB:
20.41
1oniC-1mmfB:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_H_BEZH515_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1mmf GLYCEROL DEHYDRASE
BETA SUBUNIT
(Klebsiella
pneumoniae) 		4 / 6 ARG B  70
ALA B  21
ILE B  74
PRO B 184
 None
 1.18A 1oniH-1mmfB:
undetectable
1oniI-1mmfB:
undetectable		 1oniH-1mmfB:
20.41
1oniI-1mmfB:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_A_ADNA2001_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 1mmf GLYCEROL DEHYDRASE
BETA SUBUNIT
(Klebsiella
pneumoniae) 		4 / 7 ARG B  70
GLU B  63
ALA B 143
ALA B 140
 None
 0.90A 2ejfA-1mmfB:
undetectable		 2ejfA-1mmfB:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_A_BRLA1_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 1mmf GLYCEROL DEHYDRASE
BETA SUBUNIT
(Klebsiella
pneumoniae) 		3 / 3 ILE B  54
ILE B 135
LEU B 191
 None
 0.50A 2prgA-1mmfB:
undetectable		 2prgA-1mmfB:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCP_B_CHDB4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1mmf GLYCEROL DEHYDRASE
BETA SUBUNIT
(Klebsiella
pneumoniae) 		3 / 3 GLY B  33
PRO B 184
LEU B  90
 None
 0.64A 3hcpB-1mmfB:
undetectable		 3hcpB-1mmfB:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_B_CELB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1mmf GLYCEROL DEHYDRASE
BETA SUBUNIT
(Klebsiella
pneumoniae) 		5 / 12 LEU B  55
TYR B 132
PHE B  38
ILE B  99
GLY B  33
 None
 1.25A 3kk6B-1mmfB:
0.0		 3kk6B-1mmfB:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_1
(PROTEASE)		 1mmf GLYCEROL DEHYDRASE
BETA SUBUNIT
(Klebsiella
pneumoniae) 		5 / 12 ASP B  39
GLY B  35
ILE B  74
THR B 105
ILE B  97
 None
 1.10A 3s56A-1mmfB:
undetectable		 3s56A-1mmfB:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MRA_B_DM2B204_1
(SORCIN)		 1mmf GLYCEROL DEHYDRASE
BETA SUBUNIT
(Klebsiella
pneumoniae) 		4 / 6 PHE B  82
THR B  77
ARG B  76
GLY B  33
 None
 1.18A 5mraA-1mmfB:
0.0
5mraB-1mmfB:
0.0		 5mraA-1mmfB:
20.20
5mraB-1mmfB:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_E_PFLE406_1
(PROTON-GATED ION
CHANNEL)		 1mmf GLYCEROL DEHYDRASE
BETA SUBUNIT
(Klebsiella
pneumoniae) 		5 / 10 ILE B  54
THR B 105
ILE B  99
ILE B  97
ILE B  32
 None
 1.10A 5murE-1mmfB:
undetectable		 5murE-1mmfB:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB809_1
(CATALASE-PEROXIDASE)		 1mmf GLYCEROL DEHYDRASE
BETA SUBUNIT
(Klebsiella
pneumoniae) 		4 / 8 GLU B 174
GLY B 103
GLN B 100
THR B 105
 None
 0.99A 5syjB-1mmfB:
undetectable		 5syjB-1mmfB:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YSI_A_NCAA1001_0
(UBIQUITINATING/DEUBI
QUITINATING ENZYME
SDEA)		 1mmf GLYCEROL DEHYDRASE
BETA SUBUNIT
(Klebsiella
pneumoniae) 		4 / 6 GLY B  98
SER B 101
THR B 104
VAL B  80
 None
None
B12  B 601 (-3.0A)
None
 1.21A 5ysiA-1mmfB:
0.0		 5ysiA-1mmfB:
22.16