SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mnn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 1mnn NDT80 PROTEIN
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 101
ASP A  49
ASN A 330
 None
 0.76A 1wg8B-1mnnA:
undetectable		 1wg8B-1mnnA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1mnn NDT80 PROTEIN
(Saccharomyces
cerevisiae) 		5 / 9 VAL A  78
LEU A 137
PHE A 130
SER A 240
LEU A 313
 None
 1.20A 1wrkA-1mnnA:
undetectable
1wrkB-1mnnA:
undetectable		 1wrkA-1mnnA:
14.12
1wrkB-1mnnA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1mnn NDT80 PROTEIN
(Saccharomyces
cerevisiae) 		4 / 6 VAL A  78
LEU A 137
PHE A 130
SER A 240
 None
 0.99A 1wrlB-1mnnA:
undetectable		 1wrlB-1mnnA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 1mnn NDT80 PROTEIN
(Saccharomyces
cerevisiae) 		3 / 3 PHE A 257
ARG A 177
ASN A 112
 None
 0.92A 1xzxX-1mnnA:
undetectable		 1xzxX-1mnnA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H9T_H_SVRH301_1
(THROMBIN)		 1mnn NDT80 PROTEIN
(Saccharomyces
cerevisiae) 		5 / 11 ARG A  85
VAL A 150
GLN A 151
GLY A 308
GLU A 299
 None
 1.25A 2h9tH-1mnnA:
undetectable		 2h9tH-1mnnA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMB_A_PXBA692_1
(LACTOTRANSFERRIN)		 1mnn NDT80 PROTEIN
(Saccharomyces
cerevisiae) 		3 / 3 PRO A 185
GLU A 253
TYR A 252
 None
 0.80A 2zmbA-1mnnA:
undetectable		 2zmbA-1mnnA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF6_H_SVRH301_1
(THROMBIN, HEAVY
CHAIN)		 1mnn NDT80 PROTEIN
(Saccharomyces
cerevisiae) 		5 / 11 ARG A  85
VAL A 150
GLN A 151
GLY A 308
GLU A 299
 None
 1.30A 3bf6H-1mnnA:
undetectable		 3bf6H-1mnnA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA201_1
(PROTEIN S100-A4)		 1mnn NDT80 PROTEIN
(Saccharomyces
cerevisiae) 		5 / 9 ILE A 157
PHE A 273
PHE A 114
GLY A  98
PHE A  99
 None
 1.32A 3ko0A-1mnnA:
undetectable
3ko0C-1mnnA:
undetectable		 3ko0A-1mnnA:
14.95
3ko0C-1mnnA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH201_1
(PROTEIN S100-A4)		 1mnn NDT80 PROTEIN
(Saccharomyces
cerevisiae) 		5 / 9 ILE A 157
PHE A 273
PHE A 114
GLY A  98
PHE A  99
 None
 1.38A 3ko0H-1mnnA:
undetectable
3ko0I-1mnnA:
undetectable		 3ko0H-1mnnA:
14.95
3ko0I-1mnnA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_N_TFPN201_1
(PROTEIN S100-A4)		 1mnn NDT80 PROTEIN
(Saccharomyces
cerevisiae) 		5 / 10 PHE A 114
GLY A  98
PHE A  99
ILE A 157
PHE A 273
 None
 1.49A 3ko0L-1mnnA:
undetectable
3ko0N-1mnnA:
undetectable		 3ko0L-1mnnA:
14.95
3ko0N-1mnnA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ201_1
(PROTEIN S100-A4)		 1mnn NDT80 PROTEIN
(Saccharomyces
cerevisiae) 		5 / 8 PHE A 114
GLY A  98
PHE A  99
ILE A 157
PHE A 273
 None
 1.34A 3ko0O-1mnnA:
undetectable
3ko0Q-1mnnA:
undetectable		 3ko0O-1mnnA:
14.95
3ko0Q-1mnnA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_R_TFPR201_1
(PROTEIN S100-A4)		 1mnn NDT80 PROTEIN
(Saccharomyces
cerevisiae) 		5 / 10 ILE A 157
PHE A 273
PHE A 114
GLY A  98
PHE A  99
 None
 1.37A 3ko0R-1mnnA:
undetectable
3ko0T-1mnnA:
undetectable		 3ko0R-1mnnA:
14.95
3ko0T-1mnnA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_2
(FIV PROTEASE)		 1mnn NDT80 PROTEIN
(Saccharomyces
cerevisiae) 		5 / 10 LEU A 148
ALA A 281
VAL A  78
VAL A 139
LEU A 137
 None
 1.13A 3ogpB-1mnnA:
undetectable		 3ogpB-1mnnA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VM4_A_IZPA1_1
(FATTY ACID
ALPHA-HYDROXYLASE)		 1mnn NDT80 PROTEIN
(Saccharomyces
cerevisiae) 		4 / 5 LEU A 300
PHE A 310
PRO A 189
ALA A 154
 None
 1.45A 3vm4A-1mnnA:
0.0		 3vm4A-1mnnA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI507_0
(RNA POLYMERASE
3D-POL)		 1mnn NDT80 PROTEIN
(Saccharomyces
cerevisiae) 		3 / 3 LYS A 265
PRO A 266
SER A 267
 None
 0.43A 4k50I-1mnnA:
0.0		 4k50I-1mnnA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJ4_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1mnn NDT80 PROTEIN
(Saccharomyces
cerevisiae) 		4 / 8 LEU A 148
LEU A 137
VAL A 139
ILE A 295
 None
 0.82A 4oj4A-1mnnA:
0.0		 4oj4A-1mnnA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDA_A_DEXA1985_2
(MINERALOCORTICOID
RECEPTOR)		 1mnn NDT80 PROTEIN
(Saccharomyces
cerevisiae) 		4 / 6 LEU A 131
LEU A 190
PHE A 120
THR A 122
 None
 1.07A 4udaA-1mnnA:
undetectable		 4udaA-1mnnA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1mnn NDT80 PROTEIN
(Saccharomyces
cerevisiae) 		4 / 8 PRO A 192
SER A 133
THR A  83
PHE A 135
 None
 1.21A 5t8sB-1mnnA:
undetectable		 5t8sB-1mnnA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_2
(CYTOCHROME P450 3A5)		 1mnn NDT80 PROTEIN
(Saccharomyces
cerevisiae) 		4 / 5 PHE A 310
PHE A 153
LEU A 279
LEU A 148
 None
 1.37A 5veuH-1mnnA:
0.0		 5veuH-1mnnA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1mnn NDT80 PROTEIN
(Saccharomyces
cerevisiae) 		4 / 8 GLU A 243
PHE A 153
PHE A 120
LEU A  87
 None
 1.05A 5y2tB-1mnnA:
undetectable		 5y2tB-1mnnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1mnn NDT80 PROTEIN
(Saccharomyces
cerevisiae) 		4 / 7 ILE A 155
ARG A 251
THR A 115
LEU A 116
 None
 0.92A 5zcpA-1mnnA:
undetectable
5zcpJ-1mnnA:
undetectable		 5zcpA-1mnnA:
19.89
5zcpJ-1mnnA:
14.42