SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mo2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_5
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1mo2 ERYTHRONOLIDE
SYNTHASE, MODULES 5
AND 6
(Saccharopolyspor
a
erythraea) 		4 / 4 LEU A  56
VAL A 101
CYH A  73
ALA A 148
 None
 1.29A 1mz9E-1mo2A:
0.0		 1mz9E-1mo2A:
9.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_A_FUAA702_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1mo2 ERYTHRONOLIDE
SYNTHASE, MODULES 5
AND 6
(Saccharopolyspor
a
erythraea) 		5 / 12 LEU A  56
VAL A 122
PHE A  48
ALA A 150
ALA A 120
 None
 0.98A 1q23A-1mo2A:
0.0
1q23B-1mo2A:
0.0		 1q23A-1mo2A:
19.67
1q23B-1mo2A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OC8_A_HU5A999_1
(HEPATITIS C VIRUS)		 1mo2 ERYTHRONOLIDE
SYNTHASE, MODULES 5
AND 6
(Saccharopolyspor
a
erythraea) 		5 / 12 ARG A 202
LEU A  38
GLY A  40
SER A  42
ALA A 205
 None
 0.81A 2oc8A-1mo2A:
undetectable		 2oc8A-1mo2A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_A_TPFA1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 1mo2 ERYTHRONOLIDE
SYNTHASE, MODULES 5
AND 6
(Saccharopolyspor
a
erythraea) 		5 / 10 ALA A 148
ALA A 139
LEU A  88
MET A  61
VAL A  98
 None
 1.37A 2wuzA-1mo2A:
undetectable		 2wuzA-1mo2A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_B_TPFB1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 1mo2 ERYTHRONOLIDE
SYNTHASE, MODULES 5
AND 6
(Saccharopolyspor
a
erythraea) 		5 / 10 ALA A 148
ALA A 139
LEU A  88
MET A  61
VAL A  98
 None
 1.35A 2wuzB-1mo2A:
undetectable		 2wuzB-1mo2A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F33_A_PFLA2001_1
(FERRITIN LIGHT CHAIN)		 1mo2 ERYTHRONOLIDE
SYNTHASE, MODULES 5
AND 6
(Saccharopolyspor
a
erythraea) 		4 / 6 SER A  33
TYR A  34
LEU A  37
LEU A 190
 None
 0.98A 3f33A-1mo2A:
undetectable		 3f33A-1mo2A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_A_ACRA720_1
(ALPHA-AMYLASE, SUSG)		 1mo2 ERYTHRONOLIDE
SYNTHASE, MODULES 5
AND 6
(Saccharopolyspor
a
erythraea) 		4 / 7 TYR A 149
TRP A 216
LEU A 146
TRP A 246
 None
 1.21A 3k8mA-1mo2A:
undetectable		 3k8mA-1mo2A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_B_ACRB820_1
(ALPHA-AMYLASE, SUSG)		 1mo2 ERYTHRONOLIDE
SYNTHASE, MODULES 5
AND 6
(Saccharopolyspor
a
erythraea) 		4 / 7 TYR A 149
TRP A 216
LEU A 146
TRP A 246
 None
 1.23A 3k8mB-1mo2A:
undetectable		 3k8mB-1mo2A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 1mo2 ERYTHRONOLIDE
SYNTHASE, MODULES 5
AND 6
(Saccharopolyspor
a
erythraea) 		5 / 12 LEU A 212
ALA A 121
HIS A  47
SER A  42
ASP A  43
 None
 1.30A 4aqlA-1mo2A:
2.9		 4aqlA-1mo2A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1mo2 ERYTHRONOLIDE
SYNTHASE, MODULES 5
AND 6
(Saccharopolyspor
a
erythraea) 		5 / 12 LEU A 212
LEU A 206
GLY A 207
ALA A  39
SER A  42
 None
 1.06A 4rrwC-1mo2A:
0.0		 4rrwC-1mo2A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1mo2 ERYTHRONOLIDE
SYNTHASE, MODULES 5
AND 6
(Saccharopolyspor
a
erythraea) 		5 / 12 LEU A 212
LEU A 206
GLY A 207
ALA A  39
SER A  42
 None
 1.06A 4rrzC-1mo2A:
0.0		 4rrzC-1mo2A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_B_BQ1B1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 1mo2 ERYTHRONOLIDE
SYNTHASE, MODULES 5
AND 6
(Saccharopolyspor
a
erythraea) 		5 / 8 ALA A  78
ALA A  77
ILE A  79
GLU A 185
ALA A 181
 None
 1.45A 4v1fA-1mo2A:
undetectable
4v1fB-1mo2A:
undetectable		 4v1fA-1mo2A:
17.69
4v1fB-1mo2A:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1mo2 ERYTHRONOLIDE
SYNTHASE, MODULES 5
AND 6
(Saccharopolyspor
a
erythraea) 		5 / 12 GLY A 231
ILE A  71
GLY A 164
THR A 225
LEU A 167
 None
 1.22A 4zdyA-1mo2A:
0.0		 4zdyA-1mo2A:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUJ_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 1mo2 ERYTHRONOLIDE
SYNTHASE, MODULES 5
AND 6
(Saccharopolyspor
a
erythraea) 		5 / 8 ALA A 100
VAL A  98
LEU A  92
ILE A 168
VAL A 166
 None
 1.19A 5nujA-1mo2A:
0.0		 5nujA-1mo2A:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_1
(REGULATORY PROTEIN
TETR)		 1mo2 ERYTHRONOLIDE
SYNTHASE, MODULES 5
AND 6
(Saccharopolyspor
a
erythraea) 		4 / 7 GLY A 144
TRP A 246
ASP A 169
TYR A 171
 None
 1.20A 5vlmG-1mo2A:
0.4		 5vlmG-1mo2A:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_2
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 1mo2 ERYTHRONOLIDE
SYNTHASE, MODULES 5
AND 6
(Saccharopolyspor
a
erythraea) 		4 / 6 PHE A  85
ARG A  87
LEU A  88
ALA A 139
 None
 1.09A 6b89B-1mo2A:
undetectable		 6b89B-1mo2A:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_A_SUEA1202_0
(NS3 PROTEASE)		 1mo2 ERYTHRONOLIDE
SYNTHASE, MODULES 5
AND 6
(Saccharopolyspor
a
erythraea) 		5 / 12 ARG A 202
LEU A  38
GLY A  40
SER A  42
ALA A 205
 None
 0.95A 6c2mA-1mo2A:
undetectable		 6c2mA-1mo2A:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_D_HISD402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 1mo2 ERYTHRONOLIDE
SYNTHASE, MODULES 5
AND 6
(Saccharopolyspor
a
erythraea) 		4 / 8 GLY A 279
VAL A 166
VAL A  68
LEU A 226
 None
 0.81A 6czmD-1mo2A:
undetectable
6czmF-1mo2A:
undetectable		 6czmD-1mo2A:
22.44
6czmF-1mo2A:
22.44