SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1moe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G4L_A_ROFA901_1 (CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D)	1moe	ANTI-CEA MAB T84.66 (Mus musculus)	3 / 3	ASP A 86 LEU A 108 GLN A 6	None	0.80A	3g4lA-1moeA: undetectable	3g4lA-1moeA: 19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3I5U_B_SAMB401_1 (O-METHYLTRANSFERASE)	1moe	ANTI-CEA MAB T84.66 (Mus musculus)	3 / 3	ASP A 30 PHE A 36 SER A 56	None	0.92A	3i5uB-1moeA: undetectable	3i5uB-1moeA: 22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X1B_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	1moe	ANTI-CEA MAB T84.66 (Mus musculus)	4 / 5	ARG A 18 MET A 21 THR A 76 LEU A 77	None	1.45A	5x1bW-1moeA: 0.0	5x1bW-1moeA: 11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X7P_A_ACRA1421_1 (GLYCOSIDE HYDROLASE FAMILY 31 ALPHA-GLUCOSIDASE)	1moe	ANTI-CEA MAB T84.66 (Mus musculus)	4 / 5	TYR A 91 TYR A 90 GLY A 105 GLY A 104	None	1.22A	5x7pA-1moeA: 0.9	5x7pA-1moeA: 11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NKN_J_CHDJ102_0 (CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	1moe	ANTI-CEA MAB T84.66 (Mus musculus)	4 / 5	ARG A 18 MET A 21 THR A 76 LEU A 77	None	1.45A	6nknJ-1moeA: 0.0	6nknJ-1moeA: 11.25

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3G4L_A_ROFA901_1","CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D","1moe","ANTI-CEA MAB T84.66","Mus musculus",3,"ASP A  86;LEU A 108;GLN A   6","None","0.80A","3g4lA-1moeA:undetectable","3g4lA-1moeA:19.22"],["3I5U_B_SAMB401_1","O-METHYLTRANSFERASE","1moe","ANTI-CEA MAB T84.66","Mus musculus",3,"ASP A  30;PHE A  36;SER A  56","None","0.92A","3i5uB-1moeA:undetectable","3i5uB-1moeA:22.99"],["5X1B_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","1moe","ANTI-CEA MAB T84.66","Mus musculus",4,"ARG A  18;MET A  21;THR A  76;LEU A  77","None","1.45A","5x1bW-1moeA:0.0","5x1bW-1moeA:11.25"],["5X7P_A_ACRA1421_1","GLYCOSIDE HYDROLASE FAMILY 31 ALPHA-GLUCOSIDASE","1moe","ANTI-CEA MAB T84.66","Mus musculus",4,"TYR A  91;TYR A  90;GLY A 105;GLY A 104","None","1.22A","5x7pA-1moeA:0.9","5x7pA-1moeA:11.98"],["6NKN_J_CHDJ102_0","CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","1moe","ANTI-CEA MAB T84.66","Mus musculus",4,"ARG A  18;MET A  21;THR A  76;LEU A  77","None","1.45A","6nknJ-1moeA:0.0","6nknJ-1moeA:11.25"]]