SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mor'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_A_NCAA700_0
(EXOTOXIN A)		 1mor GLUCOSAMINE
6-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 7 GLY A 471
TYR A 497
LEU A 480
ALA A 479
TYR A 476
 None
 1.02A 1dmaA-1morA:
undetectable		 1dmaA-1morA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		 1mor GLUCOSAMINE
6-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 11 ALA A 285
LEU A 289
LEU A 281
LEU A 389
ILE A 344
 None
 0.98A 1ha2A-1morA:
undetectable		 1ha2A-1morA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_F_BEZF5023_0
(CES1 PROTEIN)		 1mor GLUCOSAMINE
6-PHOSPHATE SYNTHASE
(Escherichia
coli) 		4 / 6 LEU A 346
GLY A 307
SER A 310
ILE A 295
 None
 0.90A 1yajF-1morA:
undetectable		 1yajF-1morA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1mor GLUCOSAMINE
6-PHOSPHATE SYNTHASE
(Escherichia
coli) 		4 / 5 LEU A 486
PRO A 515
ALA A 467
ILE A 492
 None
 0.93A 2aofB-1morA:
undetectable		 2aofB-1morA:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A163_1
(BETA-LACTOGLOBULIN)		 1mor GLUCOSAMINE
6-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 12 LEU A 409
VAL A 416
ILE A 344
ILE A 297
ALA A 299
 None
 1.14A 2gj5A-1morA:
undetectable		 2gj5A-1morA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RK8_A_PPFA3969_1
(PHOSPHOENOLPYRUVATE
CARBOXYKINASE,
CYTOSOLIC [GTP])		 1mor GLUCOSAMINE
6-PHOSPHATE SYNTHASE
(Escherichia
coli) 		4 / 8 HIS A 294
ASP A 323
ARG A 333
ALA A 336
 None
 1.35A 2rk8A-1morA:
undetectable		 2rk8A-1morA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN6_A_T44A1370_1
(THYROXINE-BINDING
GLOBULIN)		 1mor GLUCOSAMINE
6-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 10 LEU A 389
LEU A 371
LEU A 289
LEU A 281
ARG A 270
 None
 1.18A 2xn6A-1morA:
undetectable
2xn6B-1morA:
undetectable		 2xn6A-1morA:
21.55
2xn6B-1morA:
8.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_1
(PROTEASE)		 1mor GLUCOSAMINE
6-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 8 GLY A 540
ALA A 512
ASP A 511
ASP A 513
LEU A 543
 None
 1.49A 3em6A-1morA:
undetectable		 3em6A-1morA:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_B_SAMB270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 1mor GLUCOSAMINE
6-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 11 ALA A 372
GLY A 358
ILE A 344
SER A 347
LEU A 346
 None
None
None
G6P  A 609 (-2.8A)
None
 1.24A 3gyqB-1morA:
2.6		 3gyqB-1morA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILT_H_TRUH800_1
(GLUTAMATE RECEPTOR 2)		 1mor GLUCOSAMINE
6-PHOSPHATE SYNTHASE
(Escherichia
coli) 		3 / 3 ILE A 574
SER A 306
SER A 310
 None
 0.62A 3iltH-1morA:
undetectable		 3iltH-1morA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K5V_A_STIA2_2
(TYROSINE-PROTEIN
KINASE ABL1)		 1mor GLUCOSAMINE
6-PHOSPHATE SYNTHASE
(Escherichia
coli) 		4 / 6 LEU A 580
VAL A 411
VAL A 309
ILE A 574
 None
 1.08A 3k5vA-1morA:
undetectable		 3k5vA-1morA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB1_0
(INVASIN IPAD)		 1mor GLUCOSAMINE
6-PHOSPHATE SYNTHASE
(Escherichia
coli) 		4 / 7 ILE A 344
LEU A 371
LEU A 278
VAL A 434
 None
 0.96A 3r9vA-1morA:
1.3
3r9vB-1morA:
2.5		 3r9vA-1morA:
23.88
3r9vB-1morA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_A_NCAA1536_0
(DIPHTHERIA TOXIN)		 1mor GLUCOSAMINE
6-PHOSPHATE SYNTHASE
(Escherichia
coli) 		4 / 6 GLY A 471
TYR A 497
ALA A 479
TYR A 476
 None
 0.94A 4ae1A-1morA:
undetectable		 4ae1A-1morA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 1mor GLUCOSAMINE
6-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 12 GLY A 482
ALA A 479
VAL A 519
ALA A 584
GLN A 581
 None
 0.92A 4df3A-1morA:
undetectable		 4df3A-1morA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K38_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME
KP18CYS PEPTIDE)		 1mor GLUCOSAMINE
6-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 12 GLU A 396
GLN A 408
SER A 303
LEU A 346
LEU A 356
 None
None
G6P  A 609 (-2.7A)
None
None
 1.29A 4k38A-1morA:
undetectable
4k38D-1morA:
undetectable		 4k38A-1morA:
20.00
4k38D-1morA:
3.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K39_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 1mor GLUCOSAMINE
6-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 12 PHE A 314
ASN A 305
SER A 303
ILE A 373
LEU A 415
 None
None
G6P  A 609 (-2.7A)
None
None
 1.39A 4k39A-1morA:
undetectable		 4k39A-1morA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KT0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 1mor GLUCOSAMINE
6-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 11 SER A 362
LEU A 342
GLY A 369
ILE A 433
LEU A 437
 None
 1.05A 4kt0A-1morA:
undetectable
4kt0J-1morA:
undetectable		 4kt0A-1morA:
18.92
4kt0J-1morA:
8.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1X_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1mor GLUCOSAMINE
6-PHOSPHATE SYNTHASE
(Escherichia
coli) 		4 / 8 LEU A 389
VAL A 411
LEU A 288
LEU A 289
 None
 0.87A 4l1xA-1morA:
0.9		 4l1xA-1morA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0R_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 1mor GLUCOSAMINE
6-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 12 LEU A 371
LEU A 342
ILE A 344
LEU A 346
ILE A 297
 None
 0.83A 4y0rA-1morA:
0.1		 4y0rA-1morA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0S_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 1mor GLUCOSAMINE
6-PHOSPHATE SYNTHASE
(Escherichia
coli) 		6 / 12 LEU A 389
LEU A 371
ILE A 373
GLU A 481
ILE A 297
LEU A 278
 None
 1.10A 4y0sA-1morA:
0.0		 4y0sA-1morA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_N_EVPN2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 1mor GLUCOSAMINE
6-PHOSPHATE SYNTHASE
(Escherichia
coli) 		4 / 6 GLU A 563
GLY A 473
ARG A 472
GLY A 471
 None
 0.77A 5cdnR-1morA:
0.0
5cdnS-1morA:
3.5		 5cdnR-1morA:
23.46
5cdnS-1morA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1mor GLUCOSAMINE
6-PHOSPHATE SYNTHASE
(Escherichia
coli) 		4 / 4 LEU A 484
TYR A 497
PRO A 477
ILE A 478
 None
 1.21A 5esgA-1morA:
0.5		 5esgA-1morA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_1_PQN1842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 1mor GLUCOSAMINE
6-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 10 SER A 362
LEU A 342
GLY A 369
ILE A 433
LEU A 437
 None
 1.04A 5oy01-1morA:
undetectable
5oy07-1morA:
undetectable		 5oy01-1morA:
12.75
5oy07-1morA:
8.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WM2_A_ACTA605_0
(SALICYLATE-AMP
LIGASE)		 1mor GLUCOSAMINE
6-PHOSPHATE SYNTHASE
(Escherichia
coli) 		3 / 3 THR A 391
THR A 266
ARG A 270
 None
 1.04A 5wm2A-1morA:
2.2		 5wm2A-1morA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_D_HISD402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 1mor GLUCOSAMINE
6-PHOSPHATE SYNTHASE
(Escherichia
coli) 		4 / 8 LEU A 509
VAL A 516
VAL A 536
LEU A 468
 None
 0.84A 6czmD-1morA:
undetectable
6czmF-1morA:
undetectable		 6czmD-1morA:
24.70
6czmF-1morA:
24.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA810_0
(UNCHARACTERIZED
PROTEIN)		 1mor GLUCOSAMINE
6-PHOSPHATE SYNTHASE
(Escherichia
coli) 		4 / 6 HIS A 250
TYR A 585
GLU A 255
GLN A 253
 None
 1.24A 6d8pA-1morA:
0.0		 6d8pA-1morA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 1mor GLUCOSAMINE
6-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 10 SER A 362
LEU A 346
LEU A 381
ILE A 297
SER A 370
 None
 1.42A 6dlzB-1morA:
4.7
6dlzC-1morA:
2.0		 6dlzB-1morA:
13.47
6dlzC-1morA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 1mor GLUCOSAMINE
6-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 11 ILE A 297
SER A 370
SER A 362
LEU A 346
LEU A 381
 None
 1.42A 6dlzA-1morA:
2.1
6dlzD-1morA:
5.0		 6dlzA-1morA:
13.47
6dlzD-1morA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 1mor GLUCOSAMINE
6-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 10 SER A 362
LEU A 346
LEU A 381
ILE A 297
SER A 370
 None
 1.42A 6dm1B-1morA:
4.7
6dm1C-1morA:
2.0		 6dm1B-1morA:
13.47
6dm1C-1morA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 1mor GLUCOSAMINE
6-PHOSPHATE SYNTHASE
(Escherichia
coli) 		5 / 11 ILE A 297
SER A 370
SER A 362
LEU A 346
LEU A 381
 None
 1.42A 6dm1A-1morA:
2.0
6dm1D-1morA:
5.1		 6dm1A-1morA:
13.47
6dm1D-1morA:
13.47