SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mp3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1mp3 GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Salmonella
enterica) 		3 / 3 LEU A  41
PRO A  40
LEU A  44
 None
 0.62A 2po5B-1mp3A:
2.6		 2po5B-1mp3A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1161_1
(ALLERGEN ARG R 1)		 1mp3 GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Salmonella
enterica) 		4 / 5 VAL A 148
TYR A 146
VAL A 140
ASP A 142
 None
 1.32A 2x45A-1mp3A:
0.0		 2x45A-1mp3A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_A_SAMA300_0
(PUTATIVE RRNA
METHYLASE)		 1mp3 GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Salmonella
enterica) 		5 / 12 ASP A 111
ILE A  52
ASN A 112
LEU A 107
THR A  43
 TTP  A 501 (-3.2A)
None
None
None
None
 1.11A 3eeyA-1mp3A:
undetectable		 3eeyA-1mp3A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_0
(PUTATIVE RRNA
METHYLASE)		 1mp3 GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Salmonella
enterica) 		5 / 12 ASP A 111
ILE A  52
ASN A 112
LEU A 107
THR A  43
 TTP  A 501 (-3.2A)
None
None
None
None
 1.12A 3eeyE-1mp3A:
undetectable		 3eeyE-1mp3A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_F_SAMF300_0
(PUTATIVE RRNA
METHYLASE)		 1mp3 GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Salmonella
enterica) 		5 / 12 ASP A 111
ILE A  52
ASN A 112
LEU A 107
THR A  43
 TTP  A 501 (-3.2A)
None
None
None
None
 1.13A 3eeyF-1mp3A:
undetectable		 3eeyF-1mp3A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_I_SAMI300_0
(PUTATIVE RRNA
METHYLASE)		 1mp3 GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Salmonella
enterica) 		5 / 12 ASP A 111
ILE A  52
ASN A 112
LEU A 107
THR A  43
 TTP  A 501 (-3.2A)
None
None
None
None
 1.17A 3eeyI-1mp3A:
undetectable		 3eeyI-1mp3A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 1mp3 GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Salmonella
enterica) 		5 / 9 LEU A 107
ILE A   7
ILE A   8
TYR A  38
ILE A  55
 None
 0.94A 3zosA-1mp3A:
undetectable		 3zosA-1mp3A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQT_C_C5EC301_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1mp3 GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Salmonella
enterica) 		4 / 8 VAL A 108
TYR A 179
CYH A 105
ILE A   7
 None
 1.30A 4bqtC-1mp3A:
undetectable
4bqtD-1mp3A:
0.0		 4bqtC-1mp3A:
22.26
4bqtD-1mp3A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4II8_A_010A210_0
(LYSOZYME C)		 1mp3 GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Salmonella
enterica) 		4 / 7 ASP A 111
GLN A  26
ASN A 112
ILE A   8
 TTP  A 501 (-3.2A)
TTP  A 501 (-4.0A)
None
None
 1.17A 4ii8A-1mp3A:
undetectable		 4ii8A-1mp3A:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1804_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1mp3 GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Salmonella
enterica) 		5 / 8 GLY A 175
LEU A 109
LEU A  53
ILE A 200
ILE A 100
 None
TTP  A 501 ( 3.9A)
None
None
None
 1.16A 5vkqB-1mp3A:
undetectable
5vkqC-1mp3A:
undetectable		 5vkqB-1mp3A:
10.67
5vkqC-1mp3A:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1401_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1mp3 GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Salmonella
enterica) 		5 / 9 GLN A  91
GLN A  83
ASP A 111
GLY A 196
SER A 193
 None
TTP  A 501 (-2.9A)
TTP  A 501 (-3.2A)
None
None
 1.33A 5x7pA-1mp3A:
0.3		 5x7pA-1mp3A:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z3J_A_NCAA302_0
(ABRIN A-CHAIN)		 1mp3 GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Salmonella
enterica) 		4 / 6 VAL A 289
TYR A 284
GLU A 256
ARG A 260
 None
None
TTP  A 504 (-3.5A)
None
 0.99A 5z3jA-1mp3A:
undetectable		 5z3jA-1mp3A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_D_ACTD404_0
(L-LYSINE
3-HYDROXYLASE)		 1mp3 GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E
(Salmonella
enterica) 		4 / 6 GLN A  83
GLU A 197
ALA A  90
GLN A  91
 TTP  A 501 (-2.9A)
TTP  A 501 ( 4.9A)
None
None
 1.45A 6f6jC-1mp3A:
0.0
6f6jD-1mp3A:
0.0		 6f6jC-1mp3A:
20.75
6f6jD-1mp3A:
20.75