SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1mpp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Y_B_MK1B524_2
(PROTEIN (PROTEASE))		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 ASP A  32
GLY A  34
ASP A  37
THR A 112
ILE A 120
 None
 0.93A 1c6yB-1mppA:
7.0		 1c6yB-1mppA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDV_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 11 ASP A  32
GLY A  34
ASP A  37
ILE A  73
ILE A 120
 None
 0.69A 1sdvB-1mppA:
7.3		 1sdvB-1mppA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_2
(POL POLYPROTEIN)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		6 / 12 ASP A  32
GLY A  34
ASP A  37
ILE A  73
PRO A 111
ILE A 120
 None
 1.13A 2avoB-1mppA:
7.4		 2avoB-1mppA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_2
(GAG-POL POLYPROTEIN)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 11 ASP A 215
GLY A 217
ILE A 222
GLY A  76
ILE A 300
 None
 0.94A 2b60B-1mppA:
7.5		 2b60B-1mppA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA996_1
(GLUCOAMYLASE GLU1)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		4 / 7 ASN A 158
ASP A 159
GLY A 328
TYR A 329
 None
 1.05A 2f6dA-1mppA:
undetectable		 2f6dA-1mppA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_2
(HIV-1 PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 ASP A 215
GLY A 217
ILE A 222
GLY A  76
ILE A 300
 None
 0.87A 2hs1B-1mppA:
7.0		 2hs1B-1mppA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_2
(PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 9 LEU A  30
ASP A  32
GLY A  34
ASP A  37
ILE A 120
 None
 0.90A 2idwB-1mppA:
7.1		 2idwB-1mppA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_1
(PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ASP A  37
ILE A 120
 None
 0.86A 2ienA-1mppA:
7.3		 2ienA-1mppA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_1
(PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ASP A  37
ILE A 120
 None
 0.65A 2nmzA-1mppA:
7.1		 2nmzA-1mppA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_3
(PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ASP A  37
ILE A 120
 None
 0.73A 2nmzB-1mppA:
7.1		 2nmzB-1mppA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_B_SAMB201_1
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		4 / 5 PRO A  17
ALA A  15
ASP A  87
ASP A 118
 None
 1.00A 2nyuB-1mppA:
undetectable		 2nyuB-1mppA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4S_A_AB1A400_2
(PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 ASP A  32
GLY A  34
ASP A  37
ILE A  73
ILE A 120
 None
 0.66A 2o4sB-1mppA:
7.1		 2o4sB-1mppA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_2
(ADENOSINE KINASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		4 / 4 ALA A  15
VAL A  18
PHE A  31
THR A   4
 None
 1.09A 2pkkA-1mppA:
undetectable		 2pkkA-1mppA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_2
(PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 11 ASP A  32
GLY A  34
ASP A  37
ILE A  73
ILE A 120
 None
 0.66A 2r5qB-1mppA:
7.4		 2r5qB-1mppA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_2
(PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 10 ASP A  32
GLY A  34
ASP A  37
ILE A  73
ILE A 120
 None
 0.66A 2r5qD-1mppA:
7.4		 2r5qD-1mppA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_1
(PROTEASE RETROPEPSIN)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 ASP A 215
GLY A 217
ILE A 222
GLY A  76
ILE A 300
 None
 0.84A 2rkfA-1mppA:
7.3		 2rkfA-1mppA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_2
(PROTEASE RETROPEPSIN)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 ASP A 215
GLY A 217
ILE A 222
GLY A  76
ILE A 300
 None
 0.88A 2rkfB-1mppA:
7.4		 2rkfB-1mppA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_2
(PROTEASE RETROPEPSIN)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ASP A  37
ILE A 120
 None
 0.75A 2rkfB-1mppA:
7.4		 2rkfB-1mppA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_1
(PROTEASE RETROPEPSIN)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 ASP A 215
GLY A 217
ILE A 222
GLY A  76
ILE A 300
 None
 0.86A 2rkgA-1mppA:
7.5		 2rkgA-1mppA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_1
(PROTEASE RETROPEPSIN)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ASP A  37
ILE A 120
 None
 0.74A 2rkgA-1mppA:
7.5		 2rkgA-1mppA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_2
(PROTEASE RETROPEPSIN)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 ASP A 215
GLY A 217
ILE A 222
GLY A  76
ILE A 300
 None
 0.88A 2rkgB-1mppA:
7.5		 2rkgB-1mppA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1498_1
(CYTOCHROME P450 3A4)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 PHE A 284
LEU A 262
LEU A 260
PHE A 322
ALA A 211
 None
 1.23A 2v0mC-1mppA:
0.0		 2v0mC-1mppA:
21.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0Z_C_C41C1328_1
(RENIN)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		6 / 12 ASP A  32
GLY A  34
SER A  35
TYR A  75
ASP A 215
GLY A 217
 None
 0.32A 2v0zC-1mppA:
37.6		 2v0zC-1mppA:
31.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 10 THR A 213
GLY A  34
ASP A  32
THR A 218
ILE A 300
 None
 1.41A 3bexC-1mppA:
undetectable
3bexD-1mppA:
undetectable		 3bexC-1mppA:
21.24
3bexD-1mppA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 11 GLY A  34
ASP A  32
THR A 218
ILE A 300
THR A 213
 None
 1.37A 3bf1A-1mppA:
undetectable
3bf1B-1mppA:
undetectable		 3bf1A-1mppA:
21.24
3bf1B-1mppA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 11 THR A 213
GLY A  34
ASP A  32
THR A 218
ILE A 300
 None
 1.39A 3bf1E-1mppA:
undetectable
3bf1F-1mppA:
undetectable		 3bf1E-1mppA:
21.24
3bf1F-1mppA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUF_A_AEGA394_0
(BETA-SECRETASE 1)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		4 / 5 LEU A  30
ASP A  32
ILE A 120
GLY A 217
 None
 0.40A 3bufA-1mppA:
34.5		 3bufA-1mppA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_1
(HIV-1 PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ASP A  37
ILE A 120
 None
 0.67A 3cyxA-1mppA:
7.3		 3cyxA-1mppA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1X_A_ROCA201_2
(HIV-1 PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ASP A  37
ILE A 120
 None
 0.63A 3d1xB-1mppA:
6.8		 3d1xB-1mppA:
14.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D91_A_REMA350_1
(RENIN)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 ASP A 215
GLY A 217
LEU A  30
ASP A  32
SER A  36
 None
 0.85A 3d91A-1mppA:
37.5		 3d91A-1mppA:
31.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D91_B_REMB350_1
(RENIN)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 ASP A 215
GLY A 217
LEU A  30
ASP A  32
SER A  36
 None
 0.87A 3d91B-1mppA:
37.3		 3d91B-1mppA:
31.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_2
(PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 10 ASP A  32
GLY A  34
ASP A  37
ILE A  73
ILE A 120
 None
 0.88A 3ekpD-1mppA:
7.0		 3ekpD-1mppA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_1
(PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 10 LEU A  30
ASP A  32
GLY A  34
ASP A  37
ILE A 120
 None
 0.86A 3ekvA-1mppA:
6.8		 3ekvA-1mppA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_1
(PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 10 LEU A  30
ASP A  32
GLY A  34
ASP A  37
ILE A 120
 None
 0.82A 3em3A-1mppA:
6.8		 3em3A-1mppA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_1
(GAG-POL POLYPROTEIN)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ASP A  37
ILE A 120
 None
 0.86A 3jw2A-1mppA:
7.5		 3jw2A-1mppA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_1
(HIV-1 PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ASP A  37
ILE A 120
 None
 0.66A 3k4vA-1mppA:
7.0		 3k4vA-1mppA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_3
(HIV-1 PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ASP A  37
ILE A 120
 None
 0.61A 3k4vB-1mppA:
7.4		 3k4vB-1mppA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_1
(PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ASP A  37
ILE A 120
 None
 0.72A 3ndtA-1mppA:
7.0		 3ndtA-1mppA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_3
(PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ASP A  37
ILE A 120
 None
 0.62A 3ndtB-1mppA:
7.0		 3ndtB-1mppA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_2
(PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		6 / 11 LEU A  30
ASP A  32
GLY A  34
ASP A  37
PRO A 111
ILE A 120
 None
 1.18A 3nu3B-1mppA:
6.6		 3nu3B-1mppA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_2
(PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 9 ASP A 215
GLY A 217
ILE A 222
GLY A  76
ILE A 300
 None
 0.88A 3nu4B-1mppA:
7.0		 3nu4B-1mppA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_2
(PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 9 LEU A  30
ASP A  32
GLY A  34
ASP A  37
ILE A 120
 None
 0.73A 3nu4B-1mppA:
7.0		 3nu4B-1mppA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_1
(PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 ASP A  32
GLY A  34
ASP A  37
GLY A  76
ILE A 120
 None
 0.87A 3nu5A-1mppA:
7.3		 3nu5A-1mppA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUJ_B_478B401_2
(PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 9 LEU A  30
ASP A  32
GLY A  34
ASP A  37
ILE A 120
 None
 0.75A 3nujB-1mppA:
7.1		 3nujB-1mppA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUO_B_478B478_2
(PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 9 LEU A  30
ASP A  32
GLY A  34
ASP A  37
ILE A 120
 None
 0.79A 3nuoB-1mppA:
6.6		 3nuoB-1mppA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_1
(HIV-1 PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 9 LEU A  30
ASP A  32
GLY A  34
ASP A  37
ILE A 120
 None
 0.77A 3oxvA-1mppA:
7.1		 3oxvA-1mppA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_1
(HIV-1 PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 9 LEU A  30
ASP A  32
GLY A  34
ASP A  37
ILE A 120
 None
 0.81A 3oxvC-1mppA:
7.3		 3oxvC-1mppA:
13.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PRS_A_RITA1001_2
(ENDOTHIAPEPSIN)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		7 / 12 ASP A  32
GLY A  34
GLY A  76
PHE A 189
ASP A 215
THR A 218
ILE A 300
 None
 0.42A 3prsA-1mppA:
37.8		 3prsA-1mppA:
31.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_1
(PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ASP A  37
ILE A 120
 None
 0.68A 3pwrA-1mppA:
6.9		 3pwrA-1mppA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_3
(PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ASP A  37
ILE A 120
 None
 0.59A 3pwrB-1mppA:
7.2		 3pwrB-1mppA:
14.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PWW_A_ROCA1001_1
(ENDOTHIAPEPSIN)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		6 / 12 ASP A  32
GLY A  76
LEU A  30
PHE A 189
THR A 218
ILE A 300
 None
 1.25A 3pwwA-1mppA:
37.6		 3pwwA-1mppA:
31.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PWW_A_ROCA1001_2
(ENDOTHIAPEPSIN)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 8 GLY A  34
SER A  35
ILE A  73
TYR A  75
ASP A 215
 None
 0.36A 3pwwA-1mppA:
37.6		 3pwwA-1mppA:
31.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_1
(CANDIDAPEPSIN-2)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		7 / 12 ASP A  32
GLY A  34
GLY A  76
ASN A 128
ASP A 215
THR A 218
ILE A 300
 None
 0.30A 3q70A-1mppA:
11.1		 3q70A-1mppA:
29.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_2
(PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 10 ASP A 215
GLY A 217
ILE A 222
GLY A  76
ILE A 300
 None
 0.85A 3s43B-1mppA:
7.0		 3s43B-1mppA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_2
(PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 10 LEU A  30
ASP A  32
GLY A  34
ASP A  37
ILE A 120
 None
 0.69A 3s43B-1mppA:
7.0		 3s43B-1mppA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_1
(PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ASP A  37
ILE A 120
 None
 0.69A 3s54A-1mppA:
7.1		 3s54A-1mppA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_2
(PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ASP A  37
ILE A 120
 None
 0.71A 3s54B-1mppA:
6.4		 3s54B-1mppA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_C_9PLC1_1
(CYTOCHROME P450 2A13)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		4 / 7 PHE A 206
PHE A 227
PHE A 299
LEU A 260
 None
 1.06A 3t3sC-1mppA:
0.0		 3t3sC-1mppA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_1
(PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ASP A  37
ILE A 120
 None
 0.65A 3tkgA-1mppA:
7.2		 3tkgA-1mppA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_2
(PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ASP A  37
ILE A 120
 None
 0.84A 3tkwB-1mppA:
7.2		 3tkwB-1mppA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_1
(PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ASP A  37
ILE A 120
 None
 0.71A 3tl9A-1mppA:
6.9		 3tl9A-1mppA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_1
(SECRETED ASPARTIC
PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		6 / 12 ASP A  32
GLY A  34
ASP A   9
ASN A 128
ASP A 215
ILE A 300
 None
 1.46A 3tneA-1mppA:
37.5		 3tneA-1mppA:
29.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_1
(SECRETED ASPARTIC
PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		7 / 12 ASP A  32
GLY A  34
ILE A  73
GLY A  76
ASN A 128
ASP A 215
ILE A 300
 None
 0.49A 3tneA-1mppA:
37.5		 3tneA-1mppA:
29.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_1
(SECRETED ASPARTIC
PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		6 / 12 ILE A 120
ASP A  32
GLY A  34
GLY A  76
ASP A 215
ILE A 300
 None
 1.37A 3tneA-1mppA:
37.5		 3tneA-1mppA:
29.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		6 / 12 ASP A  32
GLY A  34
ASP A   9
ASN A 128
ASP A 215
ILE A 300
 None
 1.45A 3tneB-1mppA:
37.5		 3tneB-1mppA:
29.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		7 / 12 ASP A  32
GLY A  34
ILE A  73
GLY A  76
ASN A 128
ASP A 215
ILE A 300
 None
 0.50A 3tneB-1mppA:
37.5		 3tneB-1mppA:
29.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		6 / 12 ILE A 120
ASP A  32
GLY A  34
GLY A  76
ASP A 215
ILE A 300
 None
 1.34A 3tneB-1mppA:
37.5		 3tneB-1mppA:
29.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_2
(SECRETED ASPARTIC
PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		4 / 7 SER A  35
TYR A  75
ILE A 120
THR A 218
 None
 0.50A 3tneB-1mppA:
37.5		 3tneB-1mppA:
29.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		4 / 5 TYR A 133
SER A  35
ASP A  87
ILE A  20
 None
 1.31A 3uj7B-1mppA:
undetectable		 3uj7B-1mppA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 TYR A 133
VAL A  91
LEU A  29
PHE A  31
VAL A  18
 None
 0.99A 3w68B-1mppA:
undetectable		 3w68B-1mppA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		6 / 12 TYR A 133
VAL A  91
ILE A  73
ILE A 120
LEU A  29
VAL A  18
 None
 1.26A 3w68D-1mppA:
undetectable		 3w68D-1mppA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 TYR A 133
VAL A  91
LEU A  29
PHE A  31
VAL A  18
 None
 0.90A 3w68D-1mppA:
undetectable		 3w68D-1mppA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_B_NCAB300_0
(PROTOGLOBIN)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		4 / 7 VAL A 286
PHE A 227
VAL A 205
ILE A 271
 None
 1.00A 3zjqB-1mppA:
undetectable		 3zjqB-1mppA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_2
(ASPARTYL PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 10 LEU A  30
ASP A  32
GLY A  34
ASP A  37
ILE A 120
 None
 0.86A 4dqfB-1mppA:
7.1		 4dqfB-1mppA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_B_NCTB501_1
(CYTOCHROME P450 2A6)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		4 / 7 PHE A 258
PHE A 227
GLY A 196
PHE A 221
 None
 0.99A 4ejjB-1mppA:
0.0		 4ejjB-1mppA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H2F_A_ADNA601_1
(5'-NUCLEOTIDASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 9 ASN A 156
GLY A 162
GLY A 161
PHE A  10
GLY A 163
 None
 1.49A 4h2fA-1mppA:
undetectable		 4h2fA-1mppA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H2G_A_ADNA603_1
(5'-NUCLEOTIDASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 9 ASN A 156
GLY A 162
GLY A 161
PHE A  10
GLY A 163
 None
 1.50A 4h2gA-1mppA:
undetectable		 4h2gA-1mppA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_1
(PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 ASP A  32
GLY A  34
ASP A  37
PRO A 111
ILE A 120
 None
 1.00A 4hlaA-1mppA:
7.2		 4hlaA-1mppA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A201_2
(PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 10 LEU A  30
ASP A  32
GLY A  34
ASP A  37
ILE A 120
 None
 0.84A 4ll3B-1mppA:
7.2		 4ll3B-1mppA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A202_1
(PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 10 LEU A  30
ASP A  32
GLY A  34
ASP A  37
ILE A 120
 None
 0.88A 4ll3A-1mppA:
7.2		 4ll3A-1mppA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_2
(HIV-1 PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 9 LEU A  30
ASP A  32
GLY A  34
ASP A  37
ILE A 120
 None
 0.79A 4rvjB-1mppA:
7.0		 4rvjB-1mppA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_2
(HIV-1 PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 9 LEU A  30
ASP A  32
GLY A  34
ASP A  37
ILE A 120
 None
 0.80A 4rvjD-1mppA:
7.2		 4rvjD-1mppA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		4 / 5 PHE A 212
PRO A 193
VAL A 194
ALA A 211
 None
 1.15A 4w5oA-1mppA:
0.0		 4w5oA-1mppA:
18.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		4 / 6 LEU A 306
LEU A 260
PHE A 305
ILE A 300
 None
 1.26A 4y4dA-1mppA:
37.8		 4y4dA-1mppA:
31.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YOA_A_017A100_1
(HIV-1 PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		4 / 6 ASN A 134
ASP A 127
PRO A 149
VAL A 138
 SO4  A 501 (-3.9A)
None
None
None
 1.15A 4yoaA-1mppA:
6.4		 4yoaA-1mppA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		4 / 5 PHE A 212
PRO A 193
VAL A 194
ALA A 211
 None
 1.16A 4z4dA-1mppA:
undetectable		 4z4dA-1mppA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		4 / 5 PHE A 212
PRO A 193
VAL A 194
ALA A 211
 None
 1.14A 4z4eA-1mppA:
undetectable		 4z4eA-1mppA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_S_BEZS801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		4 / 6 PHE A 121
SER A  35
LEU A  30
LEU A  29
 None
 1.00A 5dzke-1mppA:
undetectable
5dzks-1mppA:
undetectable		 5dzke-1mppA:
20.65
5dzks-1mppA:
5.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_1
(PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 ASP A 215
GLY A 217
ILE A 222
GLY A  76
ILE A 300
 None
 0.84A 5e5jA-1mppA:
6.7		 5e5jA-1mppA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_2
(PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 ASP A 215
GLY A 217
ILE A 222
GLY A  76
ILE A 300
 None
 0.85A 5e5jB-1mppA:
7.0		 5e5jB-1mppA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_1
(HIV-1 PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 ASP A 215
GLY A 217
ILE A 222
GLY A  76
ILE A 300
 None
 0.84A 5e5kA-1mppA:
6.6		 5e5kA-1mppA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_1
(HIV-1 PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ASP A  37
ILE A 120
 None
 0.76A 5e5kA-1mppA:
6.6		 5e5kA-1mppA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_2
(HIV-1 PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 ASP A 215
GLY A 217
ILE A 222
GLY A  76
ILE A 300
 None
 0.85A 5e5kB-1mppA:
6.5		 5e5kB-1mppA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		3 / 3 ASP A 215
ASN A 219
PHE A 121
 None
 0.83A 5jglB-1mppA:
undetectable		 5jglB-1mppA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_2
(PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ASP A  37
PRO A 111
ILE A 120
 None
 1.25A 5t2zB-1mppA:
7.5		 5t2zB-1mppA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		4 / 6 PHE A 212
PRO A 193
VAL A 194
ALA A 211
 None
 1.17A 5t7bA-1mppA:
undetectable		 5t7bA-1mppA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_1
(PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 ASP A 215
GLY A 217
ILE A 222
GLY A  76
ILE A 300
 None
 0.85A 5t8hA-1mppA:
6.3		 5t8hA-1mppA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_2
(PROTEASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 ASP A 215
GLY A 217
ILE A 222
GLY A  76
ILE A 300
 None
 0.86A 5t8hB-1mppA:
7.3		 5t8hB-1mppA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		3 / 3 TYR A 133
ALA A 102
TYR A  84
 None
 0.57A 5uunB-1mppA:
0.0		 5uunB-1mppA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_B_ZITB501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		5 / 12 ASP A 289
LEU A 235
VAL A 247
PHE A 258
GLY A 302
 None
 1.13A 5uxdB-1mppA:
0.0		 5uxdB-1mppA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		3 / 3 GLY A 217
VAL A 153
MET A 155
 None
 0.63A 5ycpA-1mppA:
undetectable		 5ycpA-1mppA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA608_0
(ALPHA-AMYLASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		4 / 6 GLY A 122
THR A  38
GLN A  99
TYR A 133
 None
 1.13A 6ag0A-1mppA:
undetectable		 6ag0A-1mppA:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA608_0
(ALPHA-AMYLASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		4 / 6 PHE A 121
GLY A 122
GLN A  99
TYR A 133
 None
 1.25A 6ag0A-1mppA:
undetectable		 6ag0A-1mppA:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC606_0
(ALPHA-AMYLASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		4 / 6 GLY A 122
THR A  38
GLN A  99
TYR A 133
 None
 1.12A 6ag0C-1mppA:
undetectable		 6ag0C-1mppA:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC606_0
(ALPHA-AMYLASE)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		4 / 6 PHE A 121
GLY A 122
GLN A  99
TYR A 133
 None
 1.21A 6ag0C-1mppA:
undetectable		 6ag0C-1mppA:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		4 / 6 GLY A 119
LEU A 117
VAL A 136
PHE A  31
 None
 1.05A 6h7lA-1mppA:
undetectable		 6h7lA-1mppA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		4 / 6 GLY A 176
LEU A 175
VAL A 269
PHE A 322
 None
 1.03A 6h7lA-1mppA:
undetectable		 6h7lA-1mppA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		4 / 6 GLY A 119
LEU A 117
VAL A 136
PHE A  31
 None
 1.04A 6h7lB-1mppA:
undetectable		 6h7lB-1mppA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1mpp PEPSIN
(Rhizomucor
pusillus) 		4 / 6 GLY A 176
LEU A 175
VAL A 269
PHE A 322
 None
 1.04A 6h7lB-1mppA:
undetectable		 6h7lB-1mppA:
11.52